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The map label for this gene is glnA [H]

Identifier: 83591120

GI number: 83591120

Start: 2413292

End: 2414719

Strand: Reverse

Name: glnA [H]

Synonym: Moth_2299

Alternate gene names: 83591120

Gene position: 2414719-2413292 (Counterclockwise)

Preceding gene: 83591121

Following gene: 83591117

Centisome position: 91.86

GC content: 55.32

Gene sequence:

>1428_bases
ATGAGTAAGACACCAGGCGAAGTACTTGAGATGGCCCGAAAGAACAATATCCAGATGGTCGATCTCAAATTTATCGACCT
GCCAGGGACCTGGCAGCACTTCAGTGTGCCCTTAGACGAATTCGATGAAGGCGCTTTTACCAGCGGCGTGGGTTTTGACG
GCTCCAGCATTCGCGGTTTTAAAACCATTAACGAGAGCGATATGATCTTAGTTCCCGACCCCGATACCGCCTTTATCGAT
CCCTTCTGTGATGTGCCCACCCTCAGCCTGGTATGCAATGTCTACGACCCTATGACCGGGCAGAATTACAACCGCGATCC
CCGGTTTGTGGCCAAAAAGGCTGAAGCCTATCTAAAGGAGACCGGCATTGCCGATACCAGTTACTGGGGACCCGAGGCCG
AGTTCTTTATCCTCGATCATGTCCGCTTTGACCAGAGCCAGTACGCTGGTTACTATTTCCTGGATTCTGATGAAGGCTTC
TGGAACTCGGGCGTGGAAATGAACGGTCATCCCAACCTCGGCTACCGGCCGCGCTATAAAGAAGGTTATTTCCCGGTACC
ACCTACCGACACCCTGCAAAACTTGCGGACGGAGATGGTCCTGCTGCTGAAGCAGATGGGCATCGCCGTGGAAGCCCATC
ACCACGAGGTGGCTACTGCCGGCCAGGGCGAGATCGATATGAAGTACGCCCCCCTGACCCGGATGGCCGACCAGCTGATG
ATGTTCAAATATGTGGTCAAGAATGTGGCCATCAAGCATAATAAGACGGCTACCTTCATGCCCAAACCGGTTTTCCAGGA
CAACGGCTCGGGCATGCACGTCCACCAGAGCCTGTGGAAGGGTAACGAACCCCTCTTCTACGATGCCAATGGTTATGCGG
GGCTTAGCGAACTGGCCCTGTATTATATCGGCGGTTTGTTAAAACACGCCCCCGTCCTGACGGCCTTCTGCAGCCCGACC
ACCAACTCCTTCAAACGATTGGTGCCCGGCTTTGAAGCCCCCGTCAACCTGGTTTACTCCCAGCGTAACCGCAGCGCGGC
CATCCGCATTCCCATGTACTCCAGCAGCCCGGCCGCCAAGAGGATCGAATACCGGCCGCCCGATCCTTCCTGCAACCCGT
ACCTGGCCTTTGCCGCCCTGTTAATGGCCGGCCTGGACGGTATTAAGAACAAGATCCACCCCGGCGAGCCCCTGGATAAA
GATATCTATGACCTGCCGCCGGAAGAAGCGGCCAGGGTGAAGTCCCTGCCCGACTCCCTGGAGGAAGCCATCGCCGCCCT
GGAAAAAGACCACGAGTTCCTGCTTCAGGGAGGCGTCTTCGACGAGGACCTCATCAACGCCTGGATTGAATACAAGCAAA
AGCGGGAGATCAACCAGATCAAGCTGCGTCCCCATCCCTATGAGTTCGTTTTGTATTATGATGTTTAA

Upstream 100 bases:

>100_bases
CAAAATAGCAACCGGCAGGCTATTTAAAAAGCCGTACCTGTTGCTCCTAGATTTGGGCTACCAAAGTTTAATTTGATCTC
ACGGGAAAGGAGTTACCGGC

Downstream 100 bases:

>100_bases
ACCTGAAGACCAGCACTGCCTGCCCCCTCACCCAGGGGGCGGTTTTTTTATGGGTGGTGCAGGAGTGTCCTATTTGCTCT
ATTCCTGGCGGCTGAAGGAC

Product: L-glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSKTPGEVLEMARKNNIQMVDLKFIDLPGTWQHFSVPLDEFDEGAFTSGVGFDGSSIRGFKTINESDMILVPDPDTAFID
PFCDVPTLSLVCNVYDPMTGQNYNRDPRFVAKKAEAYLKETGIADTSYWGPEAEFFILDHVRFDQSQYAGYYFLDSDEGF
WNSGVEMNGHPNLGYRPRYKEGYFPVPPTDTLQNLRTEMVLLLKQMGIAVEAHHHEVATAGQGEIDMKYAPLTRMADQLM
MFKYVVKNVAIKHNKTATFMPKPVFQDNGSGMHVHQSLWKGNEPLFYDANGYAGLSELALYYIGGLLKHAPVLTAFCSPT
TNSFKRLVPGFEAPVNLVYSQRNRSAAIRIPMYSSSPAAKRIEYRPPDPSCNPYLAFAALLMAGLDGIKNKIHPGEPLDK
DIYDLPPEEAARVKSLPDSLEEAIAALEKDHEFLLQGGVFDEDLINAWIEYKQKREINQIKLRPHPYEFVLYYDV

Sequences:

>Translated_475_residues
MSKTPGEVLEMARKNNIQMVDLKFIDLPGTWQHFSVPLDEFDEGAFTSGVGFDGSSIRGFKTINESDMILVPDPDTAFID
PFCDVPTLSLVCNVYDPMTGQNYNRDPRFVAKKAEAYLKETGIADTSYWGPEAEFFILDHVRFDQSQYAGYYFLDSDEGF
WNSGVEMNGHPNLGYRPRYKEGYFPVPPTDTLQNLRTEMVLLLKQMGIAVEAHHHEVATAGQGEIDMKYAPLTRMADQLM
MFKYVVKNVAIKHNKTATFMPKPVFQDNGSGMHVHQSLWKGNEPLFYDANGYAGLSELALYYIGGLLKHAPVLTAFCSPT
TNSFKRLVPGFEAPVNLVYSQRNRSAAIRIPMYSSSPAAKRIEYRPPDPSCNPYLAFAALLMAGLDGIKNKIHPGEPLDK
DIYDLPPEEAARVKSLPDSLEEAIAALEKDHEFLLQGGVFDEDLINAWIEYKQKREINQIKLRPHPYEFVLYYDV
>Mature_474_residues
SKTPGEVLEMARKNNIQMVDLKFIDLPGTWQHFSVPLDEFDEGAFTSGVGFDGSSIRGFKTINESDMILVPDPDTAFIDP
FCDVPTLSLVCNVYDPMTGQNYNRDPRFVAKKAEAYLKETGIADTSYWGPEAEFFILDHVRFDQSQYAGYYFLDSDEGFW
NSGVEMNGHPNLGYRPRYKEGYFPVPPTDTLQNLRTEMVLLLKQMGIAVEAHHHEVATAGQGEIDMKYAPLTRMADQLMM
FKYVVKNVAIKHNKTATFMPKPVFQDNGSGMHVHQSLWKGNEPLFYDANGYAGLSELALYYIGGLLKHAPVLTAFCSPTT
NSFKRLVPGFEAPVNLVYSQRNRSAAIRIPMYSSSPAAKRIEYRPPDPSCNPYLAFAALLMAGLDGIKNKIHPGEPLDKD
IYDLPPEEAARVKSLPDSLEEAIAALEKDHEFLLQGGVFDEDLINAWIEYKQKREINQIKLRPHPYEFVLYYDV

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=483, Percent_Identity=24.223602484472, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1790301, Length=468, Percent_Identity=55.7692307692308, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI87081870, Length=187, Percent_Identity=32.620320855615, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 53633; Mature: 53502

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTPGEVLEMARKNNIQMVDLKFIDLPGTWQHFSVPLDEFDEGAFTSGVGFDGSSIRGF
CCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHCCCCCEECCCCCCCCCCCCE
KTINESDMILVPDPDTAFIDPFCDVPTLSLVCNVYDPMTGQNYNRDPRFVAKKAEAYLKE
EECCCCCEEEECCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
TGIADTSYWGPEAEFFILDHVRFDQSQYAGYYFLDSDEGFWNSGVEMNGHPNLGYRPRYK
CCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCC
EGYFPVPPTDTLQNLRTEMVLLLKQMGIAVEAHHHEVATAGQGEIDMKYAPLTRMADQLM
CCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHCCCCCCCEEEEECCHHHHHHHHH
MFKYVVKNVAIKHNKTATFMPKPVFQDNGSGMHVHQSLWKGNEPLFYDANGYAGLSELAL
HHHHHHHHHHEECCCCEEECCCCCCCCCCCCEEHHHHHHCCCCCEEECCCCCCCHHHHHH
YYIGGLLKHAPVLTAFCSPTTNSFKRLVPGFEAPVNLVYSQRNRSAAIRIPMYSSSPAAK
HHHHHHHHHCHHHEEECCCCHHHHHHHCCCCCCCHHHEEECCCCCEEEEEEEECCCCHHH
RIEYRPPDPSCNPYLAFAALLMAGLDGIKNKIHPGEPLDKDIYDLPPEEAARVKSLPDSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHCCHHHH
EEAIAALEKDHEFLLQGGVFDEDLINAWIEYKQKREINQIKLRPHPYEFVLYYDV
HHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEC
>Mature Secondary Structure 
SKTPGEVLEMARKNNIQMVDLKFIDLPGTWQHFSVPLDEFDEGAFTSGVGFDGSSIRGF
CCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHCCCCCEECCCCCCCCCCCCE
KTINESDMILVPDPDTAFIDPFCDVPTLSLVCNVYDPMTGQNYNRDPRFVAKKAEAYLKE
EECCCCCEEEECCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
TGIADTSYWGPEAEFFILDHVRFDQSQYAGYYFLDSDEGFWNSGVEMNGHPNLGYRPRYK
CCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCC
EGYFPVPPTDTLQNLRTEMVLLLKQMGIAVEAHHHEVATAGQGEIDMKYAPLTRMADQLM
CCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHCCCCCCCEEEEECCHHHHHHHHH
MFKYVVKNVAIKHNKTATFMPKPVFQDNGSGMHVHQSLWKGNEPLFYDANGYAGLSELAL
HHHHHHHHHHEECCCCEEECCCCCCCCCCCCEEHHHHHHCCCCCEEECCCCCCCHHHHHH
YYIGGLLKHAPVLTAFCSPTTNSFKRLVPGFEAPVNLVYSQRNRSAAIRIPMYSSSPAAK
HHHHHHHHHCHHHEEECCCCHHHHHHHCCCCCCCHHHEEECCCCCEEEEEEEECCCCHHH
RIEYRPPDPSCNPYLAFAALLMAGLDGIKNKIHPGEPLDKDIYDLPPEEAARVKSLPDSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHCCHHHH
EEAIAALEKDHEFLLQGGVFDEDLINAWIEYKQKREINQIKLRPHPYEFVLYYDV
HHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7727755; 8905231 [H]