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The map label for this gene is sdcS [H]

Identifier: 83591088

GI number: 83591088

Start: 2373679

End: 2375229

Strand: Reverse

Name: sdcS [H]

Synonym: Moth_2267

Alternate gene names: 83591088

Gene position: 2375229-2373679 (Counterclockwise)

Preceding gene: 83591089

Following gene: 83591087

Centisome position: 90.35

GC content: 52.03

Gene sequence:

>1551_bases
ATGGTAAGCTGTAACCTGCTCCCTGCTCCTTATATCTTAATAATAAAATCACCCTTTGGCAACGACAATTCAACTAATTG
CAAAGGCGGGGATAATATGGCCACTGCCACTCAAACCGGCACACAGGCGGTAGCAACCGGCAAAAAAGCTGGTACCAGGT
GGGCTTATTTTATAATCGGCCTGGCTGTCCTGGGCCTCTTCTATATCTTACCTGTTCCGGCAGGTATGAAACCTGCGGCC
ATGCGCACCCTGGGGGTAATGGCGACCACAGTTTTCTGGTGGCTGACGGAGACGCTGCCCATTCCAGTTACGGCCTTAAT
GGTGCCGTTAATGCTTCATTTTACCGGAATCCTTAGTCTGGATAAATCTGTAGCCCAGAGTTTTGGTGATAGTTTTGTTC
CTTTTTTGATAGGTGTTCTGGCCCTGTCGGTGGCCTTTACCATGTCCGGCCTGGGTAAACGGATCACTTATCTGCTGCTG
GCCCTTTCAGGTACCAAAGTTAGCCGGGTAATCGGCATTTACTTCCTGGTATCCTTTGTAATCTCCATGTTCGTCACCGA
TGTGGCCGTGGTGGCGATGATGCTGCCGATCGTAGTAGGCTTGTTACAATCCGTGGATGCCAAACCGGGGGAGAGTAACC
TGGGCCGGGGCTTGATGATGGCCATTATGTTTGGTTCTACCCTGGGCGGTATTTGTACACCTTCGGGGGTAGCTTCCAAT
GTCATTACCATGAGTTTTCTGACAAAAAACGCCAAAATAGGAGTATCGTTTCTTGACTGGGTAGCTATTGCTACACCTAT
CTTCGTAGCAGTCGGCATTATTGCCTGGTGGCTGATTCTCAAGATCTTTCCGCCGGAAATTAAAGAATTGCCCTACGGCA
AAGATATGATTCACAAAGAACTCAAGGGAATGGGCTCCTGGTCCATCGAGGAAATAACTACCATGGTTGTTTTTCTCCTG
GCGGTAGTCCTCTGGCTGACCAGTTCATGGAATGGATTGCCGATAGCTTTTGTCTCCCTTCTCATCCTGGGACTTTTATC
AATGCCGGGTGTTGGAGTTTTCAAGAAATGGAGCGATGTGGAGAAACGCCTGGAATGGGGGGCCCTGATGCTTGTAGTAG
GCGGCTTCGCCCTGGGCCTGGCAGCCAGCCAGAGTGGCCTGGCCCAGTGGGTGGCCCAGCACGCCCTGAAACCCATGACT
ATTCTTCCCCGGCCGCTGCAGCCACTGGCGGTGACCCTGTTGGTAGCAGTGGATTCCCTGGGCTTCTCCAGCTTTACAGC
AGCTGCTTCGGTTAATGTACCCTTTATCATTGCCTACGCCCAGCAGAACGCCCTGCCAGTGCTGTCGATGGCCCTGGCGG
CCGGTTTCGCCGCTTCCACCCATTTCATCCTGGTTACCGAGAGCCCGTCCTTTGTGTTACCCTATGCTTACGGGTACTTT
AGTTTTAAGGACCTTTTCAAGATTGGCGTGATTCTAACCATAGTGAGCGCCGGGGCCATTGCCATCGGCCTGGTTCTCGC
CGGCATGCCGGCAGGTGTACCGTTGCATTAA

Upstream 100 bases:

>100_bases
TCGTCAACCGCAAAGACGGGGCCATGAAGGTGGTTATCAACCCCTAAAAAAGGCTAACGGCCCGGAGCAGGCCGTTAGCG
ACGGCGGGGAGCAGTGACGG

Downstream 100 bases:

>100_bases
TATGTACCATTGCATTAATAATTGTATAAAAGGGGCCAGTCAGGCTCCTTATTTTTTTGCCCCAAAAAGCATCTATAAAA
AAGAGGAATCTGCTATTCTA

Product: Sodium/sulphate symporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MVSCNLLPAPYILIIKSPFGNDNSTNCKGGDNMATATQTGTQAVATGKKAGTRWAYFIIGLAVLGLFYILPVPAGMKPAA
MRTLGVMATTVFWWLTETLPIPVTALMVPLMLHFTGILSLDKSVAQSFGDSFVPFLIGVLALSVAFTMSGLGKRITYLLL
ALSGTKVSRVIGIYFLVSFVISMFVTDVAVVAMMLPIVVGLLQSVDAKPGESNLGRGLMMAIMFGSTLGGICTPSGVASN
VITMSFLTKNAKIGVSFLDWVAIATPIFVAVGIIAWWLILKIFPPEIKELPYGKDMIHKELKGMGSWSIEEITTMVVFLL
AVVLWLTSSWNGLPIAFVSLLILGLLSMPGVGVFKKWSDVEKRLEWGALMLVVGGFALGLAASQSGLAQWVAQHALKPMT
ILPRPLQPLAVTLLVAVDSLGFSSFTAAASVNVPFIIAYAQQNALPVLSMALAAGFAASTHFILVTESPSFVLPYAYGYF
SFKDLFKIGVILTIVSAGAIAIGLVLAGMPAGVPLH

Sequences:

>Translated_516_residues
MVSCNLLPAPYILIIKSPFGNDNSTNCKGGDNMATATQTGTQAVATGKKAGTRWAYFIIGLAVLGLFYILPVPAGMKPAA
MRTLGVMATTVFWWLTETLPIPVTALMVPLMLHFTGILSLDKSVAQSFGDSFVPFLIGVLALSVAFTMSGLGKRITYLLL
ALSGTKVSRVIGIYFLVSFVISMFVTDVAVVAMMLPIVVGLLQSVDAKPGESNLGRGLMMAIMFGSTLGGICTPSGVASN
VITMSFLTKNAKIGVSFLDWVAIATPIFVAVGIIAWWLILKIFPPEIKELPYGKDMIHKELKGMGSWSIEEITTMVVFLL
AVVLWLTSSWNGLPIAFVSLLILGLLSMPGVGVFKKWSDVEKRLEWGALMLVVGGFALGLAASQSGLAQWVAQHALKPMT
ILPRPLQPLAVTLLVAVDSLGFSSFTAAASVNVPFIIAYAQQNALPVLSMALAAGFAASTHFILVTESPSFVLPYAYGYF
SFKDLFKIGVILTIVSAGAIAIGLVLAGMPAGVPLH
>Mature_516_residues
MVSCNLLPAPYILIIKSPFGNDNSTNCKGGDNMATATQTGTQAVATGKKAGTRWAYFIIGLAVLGLFYILPVPAGMKPAA
MRTLGVMATTVFWWLTETLPIPVTALMVPLMLHFTGILSLDKSVAQSFGDSFVPFLIGVLALSVAFTMSGLGKRITYLLL
ALSGTKVSRVIGIYFLVSFVISMFVTDVAVVAMMLPIVVGLLQSVDAKPGESNLGRGLMMAIMFGSTLGGICTPSGVASN
VITMSFLTKNAKIGVSFLDWVAIATPIFVAVGIIAWWLILKIFPPEIKELPYGKDMIHKELKGMGSWSIEEITTMVVFLL
AVVLWLTSSWNGLPIAFVSLLILGLLSMPGVGVFKKWSDVEKRLEWGALMLVVGGFALGLAASQSGLAQWVAQHALKPMT
ILPRPLQPLAVTLLVAVDSLGFSSFTAAASVNVPFIIAYAQQNALPVLSMALAAGFAASTHFILVTESPSFVLPYAYGYF
SFKDLFKIGVILTIVSAGAIAIGLVLAGMPAGVPLH

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=502, Percent_Identity=25.2988047808765, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI31377715, Length=535, Percent_Identity=23.9252336448598, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4506979, Length=520, Percent_Identity=22.8846153846154, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI58761541, Length=511, Percent_Identity=23.679060665362, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI219802232, Length=448, Percent_Identity=24.5535714285714, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI301069346, Length=489, Percent_Identity=24.5398773006135, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI301069349, Length=481, Percent_Identity=23.9085239085239, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI225637552, Length=492, Percent_Identity=22.1544715447154, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI225637549, Length=483, Percent_Identity=22.360248447205, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI301069353, Length=454, Percent_Identity=21.8061674008811, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI19923838, Length=358, Percent_Identity=21.5083798882682, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI1786829, Length=467, Percent_Identity=22.9122055674518, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551790, Length=503, Percent_Identity=22.8628230616302, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71989118, Length=500, Percent_Identity=21.4, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988385, Length=449, Percent_Identity=22.9398663697105, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32565804, Length=447, Percent_Identity=22.8187919463087, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32564681, Length=478, Percent_Identity=24.0585774058577, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324340, Length=371, Percent_Identity=23.4501347708895, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322263, Length=358, Percent_Identity=23.7430167597765, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319885, Length=355, Percent_Identity=23.6619718309859, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281366409, Length=498, Percent_Identity=23.4939759036145, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737623, Length=498, Percent_Identity=23.4939759036145, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666468, Length=498, Percent_Identity=23.4939759036145, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45551633, Length=498, Percent_Identity=23.4939759036145, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281362116, Length=461, Percent_Identity=22.7765726681128, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362114, Length=461, Percent_Identity=22.7765726681128, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281362112, Length=461, Percent_Identity=22.7765726681128, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 54734; Mature: 54734

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSCNLLPAPYILIIKSPFGNDNSTNCKGGDNMATATQTGTQAVATGKKAGTRWAYFIIG
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHH
LAVLGLFYILPVPAGMKPAAMRTLGVMATTVFWWLTETLPIPVTALMVPLMLHFTGILSL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DKSVAQSFGDSFVPFLIGVLALSVAFTMSGLGKRITYLLLALSGTKVSRVIGIYFLVSFV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ISMFVTDVAVVAMMLPIVVGLLQSVDAKPGESNLGRGLMMAIMFGSTLGGICTPSGVASN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
VITMSFLTKNAKIGVSFLDWVAIATPIFVAVGIIAWWLILKIFPPEIKELPYGKDMIHKE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHH
LKGMGSWSIEEITTMVVFLLAVVLWLTSSWNGLPIAFVSLLILGLLSMPGVGVFKKWSDV
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
EKRLEWGALMLVVGGFALGLAASQSGLAQWVAQHALKPMTILPRPLQPLAVTLLVAVDSL
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GFSSFTAAASVNVPFIIAYAQQNALPVLSMALAAGFAASTHFILVTESPSFVLPYAYGYF
CCCHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEECHHHHHH
SFKDLFKIGVILTIVSAGAIAIGLVLAGMPAGVPLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVSCNLLPAPYILIIKSPFGNDNSTNCKGGDNMATATQTGTQAVATGKKAGTRWAYFIIG
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHH
LAVLGLFYILPVPAGMKPAAMRTLGVMATTVFWWLTETLPIPVTALMVPLMLHFTGILSL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DKSVAQSFGDSFVPFLIGVLALSVAFTMSGLGKRITYLLLALSGTKVSRVIGIYFLVSFV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ISMFVTDVAVVAMMLPIVVGLLQSVDAKPGESNLGRGLMMAIMFGSTLGGICTPSGVASN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
VITMSFLTKNAKIGVSFLDWVAIATPIFVAVGIIAWWLILKIFPPEIKELPYGKDMIHKE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHH
LKGMGSWSIEEITTMVVFLLAVVLWLTSSWNGLPIAFVSLLILGLLSMPGVGVFKKWSDV
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
EKRLEWGALMLVVGGFALGLAASQSGLAQWVAQHALKPMTILPRPLQPLAVTLLVAVDSL
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GFSSFTAAASVNVPFIIAYAQQNALPVLSMALAAGFAASTHFILVTESPSFVLPYAYGYF
CCCHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEECHHHHHH
SFKDLFKIGVILTIVSAGAIAIGLVLAGMPAGVPLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA