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The map label for this gene is csd [H]

Identifier: 83591037

GI number: 83591037

Start: 2311666

End: 2312817

Strand: Reverse

Name: csd [H]

Synonym: Moth_2214

Alternate gene names: 83591037

Gene position: 2312817-2311666 (Counterclockwise)

Preceding gene: 83591038

Following gene: 83591036

Centisome position: 87.98

GC content: 58.77

Gene sequence:

>1152_bases
GTGGCCATTTACCTGGATAACGCCGCCACTACCTTTCCCAAGCCGCCGGCGGTCTGGCAGGCCATGGAGCATTTTATGAA
GAATATAGGAGCCAGCGCCGGCAGGGGCGGCTACCGACGCGCCCTGGCGGCGGAAGAGATAGTCTTCCAGTGCCGGCGGC
TACTGGGGAAGTTATTTAACATTAATGACGCCACCCGCATCGTTTTTACCGCCAATGCCACTGAGGCCATCAACCTGGCC
CTCAAGGGCTGGTTGAACCCCGGCGATCATGTCATTACTACGGCTATGGAACATAATGCCGTCTGGCGCTGTTTGAAAAC
CCTGGAGAAGGAGCGCGGGATAAGCATTACCGTGGTGCCCTGCCGGGAAGACGGCGAACTGCTACTGCCAGAGCTGGATG
CGGCCTTCCGTAAGGAAACGCGCCTGCTGGCCTGCACCCATGCCTCCAATGTTACGGGAACGGTGATGCCGGTGCAGGCA
ATTACTGCCGCAGCCCACCGGCACGAGGTGCCTGTCCTGCTGGACACCGCCCAGACAGCCGGAGTATATCCCATAGATGT
CCAGGAACTGGATATCGATTTCCTGGCCTTTACCGGTCACAAAGGCCTGCTCGGACCCATGGGTACCGGCGGCCTCTATA
TACGTCCCGGTTTCGATCTGCGTCCCCTGAAGGAAGGGGGTACCGGTTCGGTGTCCCGCCTGGAGTACATGCCTGAGGGC
CTGCCGGATCGCTTCGAGGCCGGGACGCTGAATGTTGTCGGCATTGCCGGCCTTAAAGCCGCTGTGGAATATGTCCTCAA
CCAGGGGATCAGCCGGATCCGTTCCCACGAGGAGGTTCTGACGGCCAGGATGCTGGCCGGGCTGGAAGAGTTACCTGCGG
TGACCGTCTATGGTCCGAGGGAAACGGCACCCAAGGTGGGCGTGGTTTCCTTTAACATTAAAGAACTGGCCCCGGAAGAG
GTAGCCTACGCCCTGGACGAGGGCCACGAAATTATGGTCCGGGTGGGCCTGCACTGCGCGCCTCTGGCCCATAAAACCAT
AAGCACTCTGGAGCGGGGAACGGTGCGGGCCAGCGTAAGTTATTTTAATACCACGGAAGAGATAGACGCCTTTTTAACGG
CGGTAAGGGAAATTGTAGAATTAACAAGCTGA

Upstream 100 bases:

>100_bases
TCCGGGGTCGGACAGGGAGGATAGTAAGTTATCCCCCCCTTATCAGATTCCGGAAAAAAGTTGAGGCCGAATAAGAATGC
CCTGGTAGGGGGTGTAAATA

Downstream 100 bases:

>100_bases
AGTATTGAGAGTACTTGTTATCATAAGGCCCGAGCATTTCTTTCCATTTCTTATGGTGCAGGATTTAGGCAATATTAGAA
ATATGGGAGGCGGCACCCGT

Product: cysteine desulphurase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MAIYLDNAATTFPKPPAVWQAMEHFMKNIGASAGRGGYRRALAAEEIVFQCRRLLGKLFNINDATRIVFTANATEAINLA
LKGWLNPGDHVITTAMEHNAVWRCLKTLEKERGISITVVPCREDGELLLPELDAAFRKETRLLACTHASNVTGTVMPVQA
ITAAAHRHEVPVLLDTAQTAGVYPIDVQELDIDFLAFTGHKGLLGPMGTGGLYIRPGFDLRPLKEGGTGSVSRLEYMPEG
LPDRFEAGTLNVVGIAGLKAAVEYVLNQGISRIRSHEEVLTARMLAGLEELPAVTVYGPRETAPKVGVVSFNIKELAPEE
VAYALDEGHEIMVRVGLHCAPLAHKTISTLERGTVRASVSYFNTTEEIDAFLTAVREIVELTS

Sequences:

>Translated_383_residues
MAIYLDNAATTFPKPPAVWQAMEHFMKNIGASAGRGGYRRALAAEEIVFQCRRLLGKLFNINDATRIVFTANATEAINLA
LKGWLNPGDHVITTAMEHNAVWRCLKTLEKERGISITVVPCREDGELLLPELDAAFRKETRLLACTHASNVTGTVMPVQA
ITAAAHRHEVPVLLDTAQTAGVYPIDVQELDIDFLAFTGHKGLLGPMGTGGLYIRPGFDLRPLKEGGTGSVSRLEYMPEG
LPDRFEAGTLNVVGIAGLKAAVEYVLNQGISRIRSHEEVLTARMLAGLEELPAVTVYGPRETAPKVGVVSFNIKELAPEE
VAYALDEGHEIMVRVGLHCAPLAHKTISTLERGTVRASVSYFNTTEEIDAFLTAVREIVELTS
>Mature_382_residues
AIYLDNAATTFPKPPAVWQAMEHFMKNIGASAGRGGYRRALAAEEIVFQCRRLLGKLFNINDATRIVFTANATEAINLAL
KGWLNPGDHVITTAMEHNAVWRCLKTLEKERGISITVVPCREDGELLLPELDAAFRKETRLLACTHASNVTGTVMPVQAI
TAAAHRHEVPVLLDTAQTAGVYPIDVQELDIDFLAFTGHKGLLGPMGTGGLYIRPGFDLRPLKEGGTGSVSRLEYMPEGL
PDRFEAGTLNVVGIAGLKAAVEYVLNQGISRIRSHEEVLTARMLAGLEELPAVTVYGPRETAPKVGVVSFNIKELAPEEV
AYALDEGHEIMVRVGLHCAPLAHKTISTLERGTVRASVSYFNTTEEIDAFLTAVREIVELTS

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=384, Percent_Identity=27.6041666666667, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI156713448, Length=295, Percent_Identity=31.5254237288136, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1787970, Length=390, Percent_Identity=38.2051282051282, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1789175, Length=391, Percent_Identity=31.9693094629156, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI48994898, Length=401, Percent_Identity=32.1695760598504, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25143064, Length=384, Percent_Identity=27.6041666666667, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17533177, Length=247, Percent_Identity=29.9595141700405, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=395, Percent_Identity=28.1012658227848, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI20129463, Length=383, Percent_Identity=28.1984334203655, Blast_Score=117, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41652; Mature: 41521

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYLDNAATTFPKPPAVWQAMEHFMKNIGASAGRGGYRRALAAEEIVFQCRRLLGKLFN
CEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
INDATRIVFTANATEAINLALKGWLNPGDHVITTAMEHNAVWRCLKTLEKERGISITVVP
CCCCEEEEEEECCHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEE
CREDGELLLPELDAAFRKETRLLACTHASNVTGTVMPVQAITAAAHRHEVPVLLDTAQTA
ECCCCCEECCHHHHHHHHCCEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCEEEECCCCC
GVYPIDVQELDIDFLAFTGHKGLLGPMGTGGLYIRPGFDLRPLKEGGTGSVSRLEYMPEG
CCCEECHHHCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCC
LPDRFEAGTLNVVGIAGLKAAVEYVLNQGISRIRSHEEVLTARMLAGLEELPAVTVYGPR
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCEEEEECCC
ETAPKVGVVSFNIKELAPEEVAYALDEGHEIMVRVGLHCAPLAHKTISTLERGTVRASVS
CCCCCEEEEEECHHHHCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEE
YFNTTEEIDAFLTAVREIVELTS
ECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIYLDNAATTFPKPPAVWQAMEHFMKNIGASAGRGGYRRALAAEEIVFQCRRLLGKLFN
EEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
INDATRIVFTANATEAINLALKGWLNPGDHVITTAMEHNAVWRCLKTLEKERGISITVVP
CCCCEEEEEEECCHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEE
CREDGELLLPELDAAFRKETRLLACTHASNVTGTVMPVQAITAAAHRHEVPVLLDTAQTA
ECCCCCEECCHHHHHHHHCCEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCEEEECCCCC
GVYPIDVQELDIDFLAFTGHKGLLGPMGTGGLYIRPGFDLRPLKEGGTGSVSRLEYMPEG
CCCEECHHHCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCC
LPDRFEAGTLNVVGIAGLKAAVEYVLNQGISRIRSHEEVLTARMLAGLEELPAVTVYGPR
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCEEEEECCC
ETAPKVGVVSFNIKELAPEEVAYALDEGHEIMVRVGLHCAPLAHKTISTLERGTVRASVS
CCCCCEEEEEECHHHHCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEE
YFNTTEEIDAFLTAVREIVELTS
ECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]