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The map label for this gene is gcp

Identifier: 83590980

GI number: 83590980

Start: 2261054

End: 2262082

Strand: Reverse

Name: gcp

Synonym: Moth_2157

Alternate gene names: 83590980

Gene position: 2262082-2261054 (Counterclockwise)

Preceding gene: 83590981

Following gene: 83590979

Centisome position: 86.05

GC content: 63.46

Gene sequence:

>1029_bases
ATGGTAAAGGAATTGGCGACAGAAACGAATATCCTGGCCATCGAGAGTTCCTGTGATGAGACGGCGGCGGCCATTGTCAG
CGACGGCACCAGGGTCCGGGCCAACATCATCGCCTCCCAGATCGCCGTTCACCGCCGCTTTGGCGGCGTGGTGCCGGAAA
TAGCTTCCCGCCACCATATGGAGAATATAGTACCGGTGGTATCGGAGGCCCTGGCTACAGCCGGCCTGGCCTTTAGCGAT
GTGGACGCCGTGGCGGTGACCTATGGTCCCGGACTGGTAGGGGCCCTGCTGGTGGGTGTCGCTTACGCCAAGAGCCTGGC
CTACGCCCTGGGTAAGCCCCTCATCGGTGTCCACCACCTCCTGGGGCATATCTATGCCGGTTTTCTGGCCTACCCTGGCC
TGCCCTTGCCGGCGGTCTCCCTGGTGGTCTCGGGCGGGCATACCAACCTGGTCTACCTGGAGGATCACACCACCCGTCGT
ATCCTGGGGTCAACCCGGGATGACGCCGCCGGGGAAGCCTTCGACAAGGTGGCCAGGGTCCTGGGGTTGCCCTATCCGGG
CGGGCCGGAGCTGGAAAAACTGGCCCGGGAAGGCAATCCCCGGGCCATTCCTTTCCCCCGGGCCTGGCTGGAGGAAAACA
GCCTTGATTTCAGCTTTAGCGGCCTGAAATCTGCGGTCATCAACTACCTGCACCACGCCCGCCAGGTGGGCCAGGAGGTT
AACCGGGCCGACGTGGCTGCCAGTTTCCAGGCGGCGGTGGCCGAGGTCCTGGTGACCAAGACCCTGCTGGCGGCTACCAG
CTACCGGGCCAGGTCTATCCTTCTCGCCGGTGGGGTGGCGGCCAATTCGGTCCTGCGCCGGGAACTTCGTTCAGCCGGGG
AGCAGGCGGGCCTCCCGGTCTTTTTTCCACCGCGGGAACTCTGCACCGACAACGCGGCCATGATCGGCTGTGCCGCTTAT
TACCAGTACCTGCGCCGGGATTTTGCCCCTTTAAGCCTCAACGCTATCCCCGATTTACCCCTTAATTGA

Upstream 100 bases:

>100_bases
TATGAACGCCTGGGTTTTGTCAGGGCCGGGGTCCGCAGGGGCTACTATAACGACAACCGCGAAGACGCCATTATCATGTG
GAAACACCTTTTTGAGGAGA

Downstream 100 bases:

>100_bases
GAATCTCGCCATTTCGGGGGCAAAAACCCAGCAAAATCAAGGCCGGACGGGATTTGACATAATAAGGAAGTCAAAAATAG
TCCAGGTTAAAACCTAGTAA

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVKELATETNILAIESSCDETAAAIVSDGTRVRANIIASQIAVHRRFGGVVPEIASRHHMENIVPVVSEALATAGLAFSD
VDAVAVTYGPGLVGALLVGVAYAKSLAYALGKPLIGVHHLLGHIYAGFLAYPGLPLPAVSLVVSGGHTNLVYLEDHTTRR
ILGSTRDDAAGEAFDKVARVLGLPYPGGPELEKLAREGNPRAIPFPRAWLEENSLDFSFSGLKSAVINYLHHARQVGQEV
NRADVAASFQAAVAEVLVTKTLLAATSYRARSILLAGGVAANSVLRRELRSAGEQAGLPVFFPPRELCTDNAAMIGCAAY
YQYLRRDFAPLSLNAIPDLPLN

Sequences:

>Translated_342_residues
MVKELATETNILAIESSCDETAAAIVSDGTRVRANIIASQIAVHRRFGGVVPEIASRHHMENIVPVVSEALATAGLAFSD
VDAVAVTYGPGLVGALLVGVAYAKSLAYALGKPLIGVHHLLGHIYAGFLAYPGLPLPAVSLVVSGGHTNLVYLEDHTTRR
ILGSTRDDAAGEAFDKVARVLGLPYPGGPELEKLAREGNPRAIPFPRAWLEENSLDFSFSGLKSAVINYLHHARQVGQEV
NRADVAASFQAAVAEVLVTKTLLAATSYRARSILLAGGVAANSVLRRELRSAGEQAGLPVFFPPRELCTDNAAMIGCAAY
YQYLRRDFAPLSLNAIPDLPLN
>Mature_342_residues
MVKELATETNILAIESSCDETAAAIVSDGTRVRANIIASQIAVHRRFGGVVPEIASRHHMENIVPVVSEALATAGLAFSD
VDAVAVTYGPGLVGALLVGVAYAKSLAYALGKPLIGVHHLLGHIYAGFLAYPGLPLPAVSLVVSGGHTNLVYLEDHTTRR
ILGSTRDDAAGEAFDKVARVLGLPYPGGPELEKLAREGNPRAIPFPRAWLEENSLDFSFSGLKSAVINYLHHARQVGQEV
NRADVAASFQAAVAEVLVTKTLLAATSYRARSILLAGGVAANSVLRRELRSAGEQAGLPVFFPPRELCTDNAAMIGCAAY
YQYLRRDFAPLSLNAIPDLPLN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=326, Percent_Identity=34.6625766871166, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI8923380, Length=330, Percent_Identity=33.6363636363636, Blast_Score=141, Evalue=7e-34,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=44.1087613293051, Blast_Score=258, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17557464, Length=345, Percent_Identity=30.4347826086957, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71995670, Length=312, Percent_Identity=31.7307692307692, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=32.1808510638298, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=309, Percent_Identity=28.4789644012945, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129063, Length=341, Percent_Identity=32.8445747800587, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21357207, Length=317, Percent_Identity=33.4384858044164, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_MOOTA (Q2RGJ3)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430989.1
- ProteinModelPortal:   Q2RGJ3
- SMR:   Q2RGJ3
- STRING:   Q2RGJ3
- MEROPS:   M22.001
- GeneID:   3833006
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2157
- NMPDR:   fig|264732.9.peg.2183
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q2RGJ3
- BioCyc:   MTHE264732:MOTH_2157-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36282; Mature: 36282

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKELATETNILAIESSCDETAAAIVSDGTRVRANIIASQIAVHRRFGGVVPEIASRHHM
CCCHHHCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ENIVPVVSEALATAGLAFSDVDAVAVTYGPGLVGALLVGVAYAKSLAYALGKPLIGVHHL
HHHHHHHHHHHHHHCCCHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGHIYAGFLAYPGLPLPAVSLVVSGGHTNLVYLEDHTTRRILGSTRDDAAGEAFDKVARV
HHHHHHHHHHCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHH
LGLPYPGGPELEKLAREGNPRAIPFPRAWLEENSLDFSFSGLKSAVINYLHHARQVGQEV
HCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRADVAASFQAAVAEVLVTKTLLAATSYRARSILLAGGVAANSVLRRELRSAGEQAGLPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHCCCCE
FFPPRELCTDNAAMIGCAAYYQYLRRDFAPLSLNAIPDLPLN
EECCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKELATETNILAIESSCDETAAAIVSDGTRVRANIIASQIAVHRRFGGVVPEIASRHHM
CCCHHHCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ENIVPVVSEALATAGLAFSDVDAVAVTYGPGLVGALLVGVAYAKSLAYALGKPLIGVHHL
HHHHHHHHHHHHHHCCCHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGHIYAGFLAYPGLPLPAVSLVVSGGHTNLVYLEDHTTRRILGSTRDDAAGEAFDKVARV
HHHHHHHHHHCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHH
LGLPYPGGPELEKLAREGNPRAIPFPRAWLEENSLDFSFSGLKSAVINYLHHARQVGQEV
HCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRADVAASFQAAVAEVLVTKTLLAATSYRARSILLAGGVAANSVLRRELRSAGEQAGLPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHCCCCE
FFPPRELCTDNAAMIGCAAYYQYLRRDFAPLSLNAIPDLPLN
EECCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA