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The map label for this gene is moeZ [H]

Identifier: 83590802

GI number: 83590802

Start: 2053138

End: 2053947

Strand: Reverse

Name: moeZ [H]

Synonym: Moth_1970

Alternate gene names: 83590802

Gene position: 2053947-2053138 (Counterclockwise)

Preceding gene: 83590809

Following gene: 83590801

Centisome position: 78.13

GC content: 58.15

Gene sequence:

>810_bases
ATGGCCTTATCAAATGAAGAGATAGAGCGCTACAGCCGGCAAATTATCCTCAAGAACATCGGCGGCCGGGGTCAGGAAAG
GCTCAAACAGGGAAAAGTCCTGATTGTCGGCGCCGGGGGCCTTGGCTCGCCGGTAGCCTACTACCTGGCGGCGGCCGGGG
TCGGTACCCTGGGGATAATCGACAGCGATAACGTCGACCTGTCCAACCTGCAGCGCCAGATTCTCCACACCACCGGTCGT
CTCGGGCAGCCCAAGGCGGAATCCGCCCGGGAAACCCTCCTGGCCTTAAATCCAGCGCTGACCATAAACACCTACCCGCT
GAGGCTGGGTAAAGAGAATATCCTGGATATTATCCGCGATTATGACGTTATTGTTGATGGCGTCGATAACTTTCCTACCC
GTTATCTGCTCAATGACGCCTGTGTCATGACGGGTAAAACCCTGGTCGAGGCGGGCGTTCTGCAGTGGGACGGGCTGGTC
ATGACCATCAAGCCCGGCCAGGGACCCTGCTACCGTTGCATCTTTCCCGACCCGCCTCCGCCCGGAGCCGTACCGAGCTG
TCAGGAAGCCGGGGTGGTCGGCCCGGTACCAGGCGTTATCGGCTGTATCCAGGCCACGGAAGTCCTGAAGATATTGCTGG
CAACGGGGGAAACCCTTACCGGCAGGCTATTGATTTATAATGCCCTGGAGATGCGCTTCCGCGAGATCAAGGCCGAACGC
AATCCCGACTGTCCTGTCTGCGGCGATAACCCCAGCATCCGGGAACTGGAAGAGTATACTTTTGTTTGCGAAACTCAATG
CGGCAGGTGA

Upstream 100 bases:

>100_bases
ATTGACAGGATATTGTTAAAAATATTTTCTTGACCTTGGCGTTAGATCTTGATATAATCAATGCAACCCGATAAGTTTAC
TCAAGATTGGGGGCGGGGGC

Downstream 100 bases:

>100_bases
AGCCTGCTATGACCAACGATTATAAGGATATTGATTTTAATCAACTAAAAAAGGGCGGCTTTATCAGACAGCAGGGTCCC
GACCTTTTTATCATGCGGCT

Product: UBA/THIF-type NAD/FAD binding fold

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MALSNEEIERYSRQIILKNIGGRGQERLKQGKVLIVGAGGLGSPVAYYLAAAGVGTLGIIDSDNVDLSNLQRQILHTTGR
LGQPKAESARETLLALNPALTINTYPLRLGKENILDIIRDYDVIVDGVDNFPTRYLLNDACVMTGKTLVEAGVLQWDGLV
MTIKPGQGPCYRCIFPDPPPPGAVPSCQEAGVVGPVPGVIGCIQATEVLKILLATGETLTGRLLIYNALEMRFREIKAER
NPDCPVCGDNPSIRELEEYTFVCETQCGR

Sequences:

>Translated_269_residues
MALSNEEIERYSRQIILKNIGGRGQERLKQGKVLIVGAGGLGSPVAYYLAAAGVGTLGIIDSDNVDLSNLQRQILHTTGR
LGQPKAESARETLLALNPALTINTYPLRLGKENILDIIRDYDVIVDGVDNFPTRYLLNDACVMTGKTLVEAGVLQWDGLV
MTIKPGQGPCYRCIFPDPPPPGAVPSCQEAGVVGPVPGVIGCIQATEVLKILLATGETLTGRLLIYNALEMRFREIKAER
NPDCPVCGDNPSIRELEEYTFVCETQCGR
>Mature_268_residues
ALSNEEIERYSRQIILKNIGGRGQERLKQGKVLIVGAGGLGSPVAYYLAAAGVGTLGIIDSDNVDLSNLQRQILHTTGRL
GQPKAESARETLLALNPALTINTYPLRLGKENILDIIRDYDVIVDGVDNFPTRYLLNDACVMTGKTLVEAGVLQWDGLVM
TIKPGQGPCYRCIFPDPPPPGAVPSCQEAGVVGPVPGVIGCIQATEVLKILLATGETLTGRLLIYNALEMRFREIKAERN
PDCPVCGDNPSIRELEEYTFVCETQCGR

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=263, Percent_Identity=49.0494296577947, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI4885649, Length=149, Percent_Identity=33.5570469798658, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI13376212, Length=273, Percent_Identity=29.3040293040293, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI38327032, Length=257, Percent_Identity=28.7937743190661, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI23510338, Length=187, Percent_Identity=27.807486631016, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI23510340, Length=187, Percent_Identity=27.807486631016, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI38045948, Length=152, Percent_Identity=34.2105263157895, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI38045942, Length=181, Percent_Identity=30.939226519337, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI38045944, Length=181, Percent_Identity=30.939226519337, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787048, Length=251, Percent_Identity=43.0278884462151, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=42.5101214574899, Blast_Score=171, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17540406, Length=263, Percent_Identity=42.9657794676806, Blast_Score=236, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI193203301, Length=165, Percent_Identity=29.6969696969697, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17508819, Length=273, Percent_Identity=28.9377289377289, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71984476, Length=180, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=257, Percent_Identity=46.3035019455253, Blast_Score=221, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6320598, Length=177, Percent_Identity=28.8135593220339, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322639, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325323, Length=170, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=262, Percent_Identity=50.763358778626, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24660640, Length=154, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573937, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641311, Length=258, Percent_Identity=29.4573643410853, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20129973, Length=174, Percent_Identity=28.735632183908, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29123; Mature: 28992

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSNEEIERYSRQIILKNIGGRGQERLKQGKVLIVGAGGLGSPVAYYLAAAGVGTLGII
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEE
DSDNVDLSNLQRQILHTTGRLGQPKAESARETLLALNPALTINTYPLRLGKENILDIIRD
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHHH
YDVIVDGVDNFPTRYLLNDACVMTGKTLVEAGVLQWDGLVMTIKPGQGPCYRCIFPDPPP
HHHEEECCCCCCHHHHHCCHHHHCCHHHHHHCCEEECCEEEEEECCCCCEEEEECCCCCC
PGAVPSCQEAGVVGPVPGVIGCIQATEVLKILLATGETLTGRLLIYNALEMRFREIKAER
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
NPDCPVCGDNPSIRELEEYTFVCETQCGR
CCCCCCCCCCCCHHHHHHHHEEEECCCCC
>Mature Secondary Structure 
ALSNEEIERYSRQIILKNIGGRGQERLKQGKVLIVGAGGLGSPVAYYLAAAGVGTLGII
CCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEE
DSDNVDLSNLQRQILHTTGRLGQPKAESARETLLALNPALTINTYPLRLGKENILDIIRD
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHHH
YDVIVDGVDNFPTRYLLNDACVMTGKTLVEAGVLQWDGLVMTIKPGQGPCYRCIFPDPPP
HHHEEECCCCCCHHHHHCCHHHHCCHHHHHHCCEEECCEEEEEECCCCCEEEEECCCCCC
PGAVPSCQEAGVVGPVPGVIGCIQATEVLKILLATGETLTGRLLIYNALEMRFREIKAER
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
NPDCPVCGDNPSIRELEEYTFVCETQCGR
CCCCCCCCCCCCHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]