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The map label for this gene is lytT [H]

Identifier: 83590796

GI number: 83590796

Start: 2044836

End: 2045603

Strand: Reverse

Name: lytT [H]

Synonym: Moth_1964

Alternate gene names: 83590796

Gene position: 2045603-2044836 (Counterclockwise)

Preceding gene: 83590797

Following gene: 83590795

Centisome position: 77.82

GC content: 53.52

Gene sequence:

>768_bases
ATGACCTTTACCGCCGTTGTGGTTGATGACCAGCCCCTGGCTCGGGATGAACTAAAATACCTGCTGTCTGCCTACGAAGA
ATGCCAGGTCATCGGCGAAGCTGAAGACGGGGGGGAAGCCCTGCAACTGGTGGCCAGGCTGCATCCGGATGTAGTTTTCC
TGGATATCGAGATGCGGGGCATGTCCGGTTATGATGCCGCCAGGAAGATGCTGGCTGAACCCAAACCGCCCCTGATTGTT
TTTGCGACCGCCTACAACGAATACGCTGTCGGGGCCTTCGAACTGGGAGCGATAGATTATTTATTGAAACCCTTTGTGGA
CGAACGCCTGGCGAAAACCATTGAGCGGATTAAAAATCTCAAGGCGCGCCAGGAGGACTGGCAGGAGGCAGTGGCCCGGG
TCGCCCGGTTGCTGGAAGATAATCAGCAGTCAGTAAAAAAATTGCCCGTTGAGAAGAACGGGGCTATCAAACTCCTGGAT
TACGGCGACATTTTTTATGGCCGCGCCCGGGGCGGCGGGGTGCAAGTTTTTACTACCGATGATTCCTATACCTTTAGCGG
CACCATGGCGGAACTGGAAGAACGGTTAAACAGGGAAGGTTTTTTCAGGGTGCATAAGAGCTTTCTGGTTAACTTAAGAA
AGGTGGAGGGGGTGTTACCCTGGTTCAAGGGCACCTACTGGCTGGTTATGGGTGACCGGAAACGGACCCAGATTCCGGTA
AGCAAAGGTCAGGTGAAGGAGCTAAAGGTTCTGCTGGGTCTCAACTAA

Upstream 100 bases:

>100_bases
CCGGAATACGCCGTCCGGGTGAAGAGTGTCCCCGGCCAGGGTACCGAGGTGGTCCTGCGTTTTCCTAAAAAAGTTGAGCA
CCGGGAGGTGAAGGAGGAAG

Downstream 100 bases:

>100_bases
TACTCAACTAATAACGACAGCTACAGGCGAGAATCTCGGGCAAGAGCCCGAATTTTCCTACAATCGTTGCCTTCATCAGC
CCCTCCTCAAAGGGGCTCTT

Product: LytR/AlgR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTFTAVVVDDQPLARDELKYLLSAYEECQVIGEAEDGGEALQLVARLHPDVVFLDIEMRGMSGYDAARKMLAEPKPPLIV
FATAYNEYAVGAFELGAIDYLLKPFVDERLAKTIERIKNLKARQEDWQEAVARVARLLEDNQQSVKKLPVEKNGAIKLLD
YGDIFYGRARGGGVQVFTTDDSYTFSGTMAELEERLNREGFFRVHKSFLVNLRKVEGVLPWFKGTYWLVMGDRKRTQIPV
SKGQVKELKVLLGLN

Sequences:

>Translated_255_residues
MTFTAVVVDDQPLARDELKYLLSAYEECQVIGEAEDGGEALQLVARLHPDVVFLDIEMRGMSGYDAARKMLAEPKPPLIV
FATAYNEYAVGAFELGAIDYLLKPFVDERLAKTIERIKNLKARQEDWQEAVARVARLLEDNQQSVKKLPVEKNGAIKLLD
YGDIFYGRARGGGVQVFTTDDSYTFSGTMAELEERLNREGFFRVHKSFLVNLRKVEGVLPWFKGTYWLVMGDRKRTQIPV
SKGQVKELKVLLGLN
>Mature_254_residues
TFTAVVVDDQPLARDELKYLLSAYEECQVIGEAEDGGEALQLVARLHPDVVFLDIEMRGMSGYDAARKMLAEPKPPLIVF
ATAYNEYAVGAFELGAIDYLLKPFVDERLAKTIERIKNLKARQEDWQEAVARVARLLEDNQQSVKKLPVEKNGAIKLLDY
GDIFYGRARGGGVQVFTTDDSYTFSGTMAELEERLNREGFFRVHKSFLVNLRKVEGVLPWFKGTYWLVMGDRKRTQIPVS
KGQVKELKVLLGLN

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=250, Percent_Identity=32, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87082052, Length=251, Percent_Identity=35.0597609561753, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=34.1269841269841, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788521, Length=114, Percent_Identity=34.2105263157895, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28856; Mature: 28724

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTAVVVDDQPLARDELKYLLSAYEECQVIGEAEDGGEALQLVARLHPDVVFLDIEMRG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEEEEEEECC
MSGYDAARKMLAEPKPPLIVFATAYNEYAVGAFELGAIDYLLKPFVDERLAKTIERIKNL
CCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARQEDWQEAVARVARLLEDNQQSVKKLPVEKNGAIKLLDYGDIFYGRARGGGVQVFTTD
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEECC
DSYTFSGTMAELEERLNREGFFRVHKSFLVNLRKVEGVLPWFKGTYWLVMGDRKRTQIPV
CCEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCC
SKGQVKELKVLLGLN
CCCCHHHHHEEECCC
>Mature Secondary Structure 
TFTAVVVDDQPLARDELKYLLSAYEECQVIGEAEDGGEALQLVARLHPDVVFLDIEMRG
EEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEEEEEEECC
MSGYDAARKMLAEPKPPLIVFATAYNEYAVGAFELGAIDYLLKPFVDERLAKTIERIKNL
CCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARQEDWQEAVARVARLLEDNQQSVKKLPVEKNGAIKLLDYGDIFYGRARGGGVQVFTTD
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEECC
DSYTFSGTMAELEERLNREGFFRVHKSFLVNLRKVEGVLPWFKGTYWLVMGDRKRTQIPV
CCEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCC
SKGQVKELKVLLGLN
CCCCHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]