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The map label for this gene is glgC [C]

Identifier: 83590759

GI number: 83590759

Start: 1996599

End: 1999064

Strand: Reverse

Name: glgC [C]

Synonym: Moth_1925

Alternate gene names: 83590759

Gene position: 1999064-1996599 (Counterclockwise)

Preceding gene: 83590760

Following gene: 83590758

Centisome position: 76.05

GC content: 63.83

Gene sequence:

>2466_bases
ATGAAAGCAATCATCATGGCCGGCGGGGAAGGGTCGCGCTTGCGGCCCCTGACCTGCAAGCGGCCCAAACCCCTGGTGCC
GGTGGCCAACCGGCCGGTGATGGAGTACTGCGTGGACCTGCTGCGTGAACTTGGTATCAAAGAGGTAGGGGTGACCCTGC
AGTACCTGCCGCAACTTATTGAGGAATATTTTGGGGACGGCAGTGATTTCGGCCTGCACCTGCATTACTTTGTCGAGGAT
AAGCCCCTGGGTACCGCCGGGAGCGTCAAGAATGCGGCCGCTATTTTAGATGAAACCTTTGTGGTGGTGAGCGGCGACGC
CCTGACGGATTTTGACCTGCGGCCGGCCATTGCCCGGCATAAGGAAAGCGGCGCCCTGGCCACCCTGGTACTTACTGCAG
TGGATAACCCCCTGGAGTACGGGGTGGTTATCACCAACCCCGACGGCAGCATCCGTTCCTTCCTGGAGAAACCGAGCTGG
GGCGAGGTTTTCAGCGACCGGGTCAACACAGGCATCTATATCCTGGAGCCGGAGGTCCTGGAACTGATCCCCGAGGGCCG
GCCCTTTGATTTCAGCAAGGACCTCTTTCCCCGGCTGTTAAAGGAAAAGCGACCCCTCTACGGGGTGACCCTTTCCGGCT
ACTGGTGCGATATCGGTAACCTTACCCAATACCGCCAGGCCCAGGAGGATATCCTGCGGGGCCGGGTGAAGGTCCGGGTG
GTGGGCCAGGATAAGGGTGGCGGTGTGGTGATGGGTGAAGGGGTGGAGATTGCCCCCGGGGCGCGGATTGAAGGCCCGGT
CCTTATCGGTGGAGCCTGCCACATTGCCACCGGGGCCGTTGTTGGCCCCTTTACCGTTCTCGGGCCCTACACCCGGGTGG
AAGAAGGGGCCACTGTCAGGCGATCCGTCCTTTGGGACAACGTTTATACCGGTGAAGGGGCCAACGTCAGGGGGGCGGTA
GTTTGTAGCCGGGCCAGCCTCCAGCGCCGGGTACAGGTCTATGAAGGTGCCGTCATTGGCGACGGCACCCAGGTGGATGC
CGGGGCCGAGGTGCGCCCGGAGGTCAAGGTCTGGCCGGAGAAAACCCTGGGCCGGGAGACGGTGGTCCATGAGAGCCTTA
TCTGGGGCCGGGGTGTAGCCCGCCCCCTTTTTGTCGGCAGCCAGGCCCCTGGTTACCTGCACGGCGACCTGACTCCCTTC
CAGGTAACAAGGCTGGGTATGGCTTACGGCGCCAGTTTCCCTCCCGGCACTACGGTGGGCCTCAGCACCTTCGCCGGCGG
GGCCGGGGAAATGCTTTATAAAGCCCTGGCCGCCGGCCTAATGGCTGCCGGGGTGCAGGTGGCCGATCTGGGCCGGTTGT
TGACGCCCATACACCGTTTTGCCGTCCGTTCCCTGGGGCTCGACGGCGGTTGCCATATCAAGCGAGATGCAGCGGAAAGG
GACAAGGTGTGGCTGCACCTGGTAAACTCTCGGGGCCACGACTTAAACCCCGCAGCGGTGCGCAAGATTGAGAACCTCTA
CTGGCGGGAGGACGGTCGCCGGGTGCAGGAGGTCCCGGCCAGCATTTATTTTCCGGGCCTTGAAGGGGCCTACCGGGATT
GGTTGCTGGCGACCCTGGGAGACCATGGCCTGAAGAAAAGGGCCCTGCGGGTAGCCCTGGGGGGACAGGGACAGGTAGCC
GGGGTGGCCGGCACCATCCTCCAGGACGCCGGGGCCGAAGTTATTCGCCTGGACCTGGATCCCGCCAAAACCTGGCAGGC
CGTCCAGGAAGATTTGCCCTACTTCGCCGGGGAAATCCGGCGTTATGGCGCTGATCTGGGGGCGGCCCTGGACTCCAATG
GCGAGGAATTGATCCTCTTCACCGGCGAGGGACGGCGGGTGGCCCCGGCGCAGCAAATGACCCTCCTGGCCCGGGTTTAC
CTGGAGACCCACCGGGGAGCCAGCCTGGTTTTACCCGTGACGGCACCGCGGGTGCTGGAACAGGTCGCCGGGGGTCTCCA
CGGCCGGGTGGAGCGGGTGAAGGGCCATCCCGGCATCTATCATGAGGCCATGGCCCGGGCGGACGGGGAAACAGCTTTAG
GTCAGCAGCACCTGCAACTGGACGCCCTGGCGGCCCTCGTGCACATCCTGGACTGGCTGGCCAGCAGGGAGGAAAGCCTG
GACTCTGCAGTGGCCGCCCTGCCTCCGGTTTACACCGCGAGCCGTACCGTAGCCTGCCCCTGGGAGGCCAAGGGGAGGGT
CATGCGCACTCTCATCAGCGAGGAACCGGCAGACGGGGTGGAGCTCCTCGACGGGGTCCAGGTGCGCCATGGGAAGGGCT
GGTCCTTGGTTCTGCCTGACGGGGAGACGCCCCATTACCACATCTATAGCGAGGCCTTTTCCCAGGAGGCGGCCGAAGAG
CTGGCCGGCTTTTATGAGGAACGCCTCAAGGAGCTAATCGCCAGGGAAAAAAGTAAAGGGAGGTAG

Upstream 100 bases:

>100_bases
TGGTTTTTCTGGGAGTATATAGTAATAATAGAAAAGGCGCCAAAGGGGCATACTGCCTCTGGGAAATTTTTAATCCGGAG
GCAGGAGGTAGAAATATTTT

Downstream 100 bases:

>100_bases
GCCCTCCCCGGGCTCGCCGGGAACCCCGGGATTAATCATTCCCAGTGTTTCCTGGTGCTGCGACCCGGGCGGCAGGGATG
TTTGACCTCGACATATGGAG

Product: nucleotidyl transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 821; Mature: 821

Protein sequence:

>821_residues
MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVGVTLQYLPQLIEEYFGDGSDFGLHLHYFVED
KPLGTAGSVKNAAAILDETFVVVSGDALTDFDLRPAIARHKESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSW
GEVFSDRVNTGIYILEPEVLELIPEGRPFDFSKDLFPRLLKEKRPLYGVTLSGYWCDIGNLTQYRQAQEDILRGRVKVRV
VGQDKGGGVVMGEGVEIAPGARIEGPVLIGGACHIATGAVVGPFTVLGPYTRVEEGATVRRSVLWDNVYTGEGANVRGAV
VCSRASLQRRVQVYEGAVIGDGTQVDAGAEVRPEVKVWPEKTLGRETVVHESLIWGRGVARPLFVGSQAPGYLHGDLTPF
QVTRLGMAYGASFPPGTTVGLSTFAGGAGEMLYKALAAGLMAAGVQVADLGRLLTPIHRFAVRSLGLDGGCHIKRDAAER
DKVWLHLVNSRGHDLNPAAVRKIENLYWREDGRRVQEVPASIYFPGLEGAYRDWLLATLGDHGLKKRALRVALGGQGQVA
GVAGTILQDAGAEVIRLDLDPAKTWQAVQEDLPYFAGEIRRYGADLGAALDSNGEELILFTGEGRRVAPAQQMTLLARVY
LETHRGASLVLPVTAPRVLEQVAGGLHGRVERVKGHPGIYHEAMARADGETALGQQHLQLDALAALVHILDWLASREESL
DSAVAALPPVYTASRTVACPWEAKGRVMRTLISEEPADGVELLDGVQVRHGKGWSLVLPDGETPHYHIYSEAFSQEAAEE
LAGFYEERLKELIAREKSKGR

Sequences:

>Translated_821_residues
MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVGVTLQYLPQLIEEYFGDGSDFGLHLHYFVED
KPLGTAGSVKNAAAILDETFVVVSGDALTDFDLRPAIARHKESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSW
GEVFSDRVNTGIYILEPEVLELIPEGRPFDFSKDLFPRLLKEKRPLYGVTLSGYWCDIGNLTQYRQAQEDILRGRVKVRV
VGQDKGGGVVMGEGVEIAPGARIEGPVLIGGACHIATGAVVGPFTVLGPYTRVEEGATVRRSVLWDNVYTGEGANVRGAV
VCSRASLQRRVQVYEGAVIGDGTQVDAGAEVRPEVKVWPEKTLGRETVVHESLIWGRGVARPLFVGSQAPGYLHGDLTPF
QVTRLGMAYGASFPPGTTVGLSTFAGGAGEMLYKALAAGLMAAGVQVADLGRLLTPIHRFAVRSLGLDGGCHIKRDAAER
DKVWLHLVNSRGHDLNPAAVRKIENLYWREDGRRVQEVPASIYFPGLEGAYRDWLLATLGDHGLKKRALRVALGGQGQVA
GVAGTILQDAGAEVIRLDLDPAKTWQAVQEDLPYFAGEIRRYGADLGAALDSNGEELILFTGEGRRVAPAQQMTLLARVY
LETHRGASLVLPVTAPRVLEQVAGGLHGRVERVKGHPGIYHEAMARADGETALGQQHLQLDALAALVHILDWLASREESL
DSAVAALPPVYTASRTVACPWEAKGRVMRTLISEEPADGVELLDGVQVRHGKGWSLVLPDGETPHYHIYSEAFSQEAAEE
LAGFYEERLKELIAREKSKGR
>Mature_821_residues
MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVGVTLQYLPQLIEEYFGDGSDFGLHLHYFVED
KPLGTAGSVKNAAAILDETFVVVSGDALTDFDLRPAIARHKESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSW
GEVFSDRVNTGIYILEPEVLELIPEGRPFDFSKDLFPRLLKEKRPLYGVTLSGYWCDIGNLTQYRQAQEDILRGRVKVRV
VGQDKGGGVVMGEGVEIAPGARIEGPVLIGGACHIATGAVVGPFTVLGPYTRVEEGATVRRSVLWDNVYTGEGANVRGAV
VCSRASLQRRVQVYEGAVIGDGTQVDAGAEVRPEVKVWPEKTLGRETVVHESLIWGRGVARPLFVGSQAPGYLHGDLTPF
QVTRLGMAYGASFPPGTTVGLSTFAGGAGEMLYKALAAGLMAAGVQVADLGRLLTPIHRFAVRSLGLDGGCHIKRDAAER
DKVWLHLVNSRGHDLNPAAVRKIENLYWREDGRRVQEVPASIYFPGLEGAYRDWLLATLGDHGLKKRALRVALGGQGQVA
GVAGTILQDAGAEVIRLDLDPAKTWQAVQEDLPYFAGEIRRYGADLGAALDSNGEELILFTGEGRRVAPAQQMTLLARVY
LETHRGASLVLPVTAPRVLEQVAGGLHGRVERVKGHPGIYHEAMARADGETALGQQHLQLDALAALVHILDWLASREESL
DSAVAALPPVYTASRTVACPWEAKGRVMRTLISEEPADGVELLDGVQVRHGKGWSLVLPDGETPHYHIYSEAFSQEAAEE
LAGFYEERLKELIAREKSKGR

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=371, Percent_Identity=31.8059299191375, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI11761619, Length=342, Percent_Identity=32.4561403508772, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI31881779, Length=386, Percent_Identity=26.9430051813472, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI45447090, Length=386, Percent_Identity=26.9430051813472, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1789837, Length=400, Percent_Identity=26, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788351, Length=198, Percent_Identity=33.8383838383838, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790224, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788361, Length=407, Percent_Identity=26.2899262899263, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788355, Length=270, Percent_Identity=24.8148148148148, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=362, Percent_Identity=32.0441988950276, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17509979, Length=343, Percent_Identity=24.7813411078717, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509981, Length=328, Percent_Identity=24.0853658536585, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=386, Percent_Identity=32.1243523316062, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI21355443, Length=345, Percent_Identity=31.5942028985507, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24644084, Length=345, Percent_Identity=31.5942028985507, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653912, Length=202, Percent_Identity=29.2079207920792, Blast_Score=81, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 88961; Mature: 88961

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVGVTLQYLPQLI
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EEYFGDGSDFGLHLHYFVEDKPLGTAGSVKNAAAILDETFVVVSGDALTDFDLRPAIARH
HHHCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEECCCEECCCCCHHHHHC
KESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSWGEVFSDRVNTGIYILEPEVL
CCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHCCCCEEEECCHHH
ELIPEGRPFDFSKDLFPRLLKEKRPLYGVTLSGYWCDIGNLTQYRQAQEDILRGRVKVRV
HHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECEEECCCCHHHHHHHHHHHHCCEEEEEE
VGQDKGGGVVMGEGVEIAPGARIEGPVLIGGACHIATGAVVGPFTVLGPYTRVEEGATVR
EECCCCCCEEEECCEEECCCCCCCCCEEECCHHHHHCCCEECCHHHHCCCHHHHCCCHHH
RSVLWDNVYTGEGANVRGAVVCSRASLQRRVQVYEGAVIGDGTQVDAGAEVRPEVKVWPE
HHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCEEECCCCEECCCCCCCCCEEECCC
KTLGRETVVHESLIWGRGVARPLFVGSQAPGYLHGDLTPFQVTRLGMAYGASFPPGTTVG
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCC
LSTFAGGAGEMLYKALAAGLMAAGVQVADLGRLLTPIHRFAVRSLGLDGGCHIKRDAAER
HHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCC
DKVWLHLVNSRGHDLNPAAVRKIENLYWREDGRRVQEVPASIYFPGLEGAYRDWLLATLG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEECCCCCCHHHHHHHHHHC
DHGLKKRALRVALGGQGQVAGVAGTILQDAGAEVIRLDLDPAKTWQAVQEDLPYFAGEIR
CCHHHHHEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCHHHHHHH
RYGADLGAALDSNGEELILFTGEGRRVAPAQQMTLLARVYLETHRGASLVLPVTAPRVLE
HHHHHHHHHHCCCCCEEEEEECCCCEECHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
QVAGGLHGRVERVKGHPGIYHEAMARADGETALGQQHLQLDALAALVHILDWLASREESL
HHHCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSAVAALPPVYTASRTVACPWEAKGRVMRTLISEEPADGVELLDGVQVRHGKGWSLVLPD
HHHHHHCCCCEECCCEEECCCHHCHHHHHHHHHCCCCCCHHHHCCCEEECCCCEEEEECC
GETPHYHIYSEAFSQEAAEELAGFYEERLKELIAREKSKGR
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVGVTLQYLPQLI
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EEYFGDGSDFGLHLHYFVEDKPLGTAGSVKNAAAILDETFVVVSGDALTDFDLRPAIARH
HHHCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEECCCEECCCCCHHHHHC
KESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSWGEVFSDRVNTGIYILEPEVL
CCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHCCCCEEEECCHHH
ELIPEGRPFDFSKDLFPRLLKEKRPLYGVTLSGYWCDIGNLTQYRQAQEDILRGRVKVRV
HHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECEEECCCCHHHHHHHHHHHHCCEEEEEE
VGQDKGGGVVMGEGVEIAPGARIEGPVLIGGACHIATGAVVGPFTVLGPYTRVEEGATVR
EECCCCCCEEEECCEEECCCCCCCCCEEECCHHHHHCCCEECCHHHHCCCHHHHCCCHHH
RSVLWDNVYTGEGANVRGAVVCSRASLQRRVQVYEGAVIGDGTQVDAGAEVRPEVKVWPE
HHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCEEECCCCEECCCCCCCCCEEECCC
KTLGRETVVHESLIWGRGVARPLFVGSQAPGYLHGDLTPFQVTRLGMAYGASFPPGTTVG
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCC
LSTFAGGAGEMLYKALAAGLMAAGVQVADLGRLLTPIHRFAVRSLGLDGGCHIKRDAAER
HHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCC
DKVWLHLVNSRGHDLNPAAVRKIENLYWREDGRRVQEVPASIYFPGLEGAYRDWLLATLG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEECCCCCCHHHHHHHHHHC
DHGLKKRALRVALGGQGQVAGVAGTILQDAGAEVIRLDLDPAKTWQAVQEDLPYFAGEIR
CCHHHHHEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCHHHHHHH
RYGADLGAALDSNGEELILFTGEGRRVAPAQQMTLLARVYLETHRGASLVLPVTAPRVLE
HHHHHHHHHHCCCCCEEEEEECCCCEECHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
QVAGGLHGRVERVKGHPGIYHEAMARADGETALGQQHLQLDALAALVHILDWLASREESL
HHHCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSAVAALPPVYTASRTVACPWEAKGRVMRTLISEEPADGVELLDGVQVRHGKGWSLVLPD
HHHHHHCCCCEECCCEEECCCHHCHHHHHHHHHCCCCCCHHHHCCCEEECCCCEEEEECC
GETPHYHIYSEAFSQEAAEELAGFYEERLKELIAREKSKGR
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA