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The map label for this gene is yfnA [H]

Identifier: 83590754

GI number: 83590754

Start: 1991746

End: 1993146

Strand: Reverse

Name: yfnA [H]

Synonym: Moth_1920

Alternate gene names: 83590754

Gene position: 1993146-1991746 (Counterclockwise)

Preceding gene: 83590755

Following gene: 83590752

Centisome position: 75.82

GC content: 54.89

Gene sequence:

>1401_bases
ATGGCCAGCAGTATCTTGCGCAAAAAAGATATCGCTACAGCCATGGAAATGGCTGCCATGGACCAATATCGGCTTCGCCG
GGAGTTGAAGGCCATGGATCTCTTTTTTCTGGTAATAGGTATTACCATAGGTGGGGGGATATTCGTCCTGCCGGGGGTCA
TGGCGGCGGAACACGCAGGTCCCGGGGTTACTATTTCTTTTTTAATCGGCGCGGTGGTAGCCATCTTTACCGGCCTGTGT
TATGTTGAGTTTGCTTCTATGGTCCCGGTGGCGGGAAGCGCTTATACTTATTCTTATATTGCCCTGGGAGAGATATTTGC
CTGGATCATCGGTTGGGATGTCCTCCTGGAGTTCACCCTGGTCTGCAGCGCCGTGGCTGTGGGCTGGTCCGGCTATATCG
TTGAGTTGTTAAAGGATATGGGCCTGAGTCTGCCCCCGGCCTTTACTACCGATATAGCCCACGGCGGTATAGTCAACCTG
CCGGCGGTTTTCATCCTCCTGGTGGTGGCTTATATTATTTACGGCGGTATCAGCCTGACAGGTAAGGTCAACGATGCCAT
TGGGATTATAAAGCTCCTCACCGTGGTGTTTTTTATTATCGTGGCCCTCCCCTTTGTTAAACCGGTAAACTGGCAACCCT
TTTTGCCCTTCGGCTGGCAAGGGGTTATGACTGCTGCCGCCCTGGGCTTCTTTGCTTACGGTGGTTTCGACGCCGTCACA
ACTGCCGCCGAGGAGACCCGGAACCCCAACCGCGATATACCCTTAGGCCTGATCCTGGGACTGGTGGTAGTGGCTTCTCT
TTATGTTCTTGTCTCCCTGGTGCTGACGGGGGTTATTCCTTACACCAAACTCGATACCCCGGCACCTGTGGCTTTTGCCC
TCTCCTACCTGGGCAAACGCTGGGGCGGGAGTCTGGTAGCCGCCGGGGCCATCTGCGGCCTTTTTACAGTTATGATGGGG
GCTATGCTGGGTGGGAGCCGCATCCTGTTCGCCCTCAGCCGCGACGGTCTATTGCCGCCGGTTTTTTCCCGGGTACACGC
AACCAGGCGTACTCCCTACGTTGCCACATTGATCGTCCTGACAGTGGCCGTCCTGACAGGCGGTTTCCTCTCCCTGGGAG
AATTGGTGGAACTGGTGAATATCGGCATGCTCACCGCCTACCTCCTGACCTCTATTTCCATCCTGGTCATGCGCTTGAGA
TACCCGGAAATTGAACGACCCTTCAGGGTTCCCGCCGTATGGTTGGTGGCGCCGGTAGCCACCCTGGGAGTCGTGGCCCT
GACCTTCAGCTTGCCAGGAGCGACGTTGGTTAGATTTGCCATCTGGTTTATAGTCGGGATGCTTATCTACTTTGGCTATG
GTATCAGGCACTCGAAGCTGGCTAACCGGGAAAATAATTAA

Upstream 100 bases:

>100_bases
GCCTTAAAAATCAGGAGGCGCTAAATTTTAGGGCAAGGTCATGGCGGGATAAAGAAGGAAATATAGAAGGAAAATGGTTT
AAGGGATGGGGAGAAAGAAT

Downstream 100 bases:

>100_bases
TCTTCATGGCTTCCCGGACCTGGGCCATAGTTTCTTTCGCCACCGCCCGGGCGCGCGCCGTCCCGGCCAGGAGGATTTCA
TCAACCAATTTAGGGTTGGC

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MASSILRKKDIATAMEMAAMDQYRLRRELKAMDLFFLVIGITIGGGIFVLPGVMAAEHAGPGVTISFLIGAVVAIFTGLC
YVEFASMVPVAGSAYTYSYIALGEIFAWIIGWDVLLEFTLVCSAVAVGWSGYIVELLKDMGLSLPPAFTTDIAHGGIVNL
PAVFILLVVAYIIYGGISLTGKVNDAIGIIKLLTVVFFIIVALPFVKPVNWQPFLPFGWQGVMTAAALGFFAYGGFDAVT
TAAEETRNPNRDIPLGLILGLVVVASLYVLVSLVLTGVIPYTKLDTPAPVAFALSYLGKRWGGSLVAAGAICGLFTVMMG
AMLGGSRILFALSRDGLLPPVFSRVHATRRTPYVATLIVLTVAVLTGGFLSLGELVELVNIGMLTAYLLTSISILVMRLR
YPEIERPFRVPAVWLVAPVATLGVVALTFSLPGATLVRFAIWFIVGMLIYFGYGIRHSKLANRENN

Sequences:

>Translated_466_residues
MASSILRKKDIATAMEMAAMDQYRLRRELKAMDLFFLVIGITIGGGIFVLPGVMAAEHAGPGVTISFLIGAVVAIFTGLC
YVEFASMVPVAGSAYTYSYIALGEIFAWIIGWDVLLEFTLVCSAVAVGWSGYIVELLKDMGLSLPPAFTTDIAHGGIVNL
PAVFILLVVAYIIYGGISLTGKVNDAIGIIKLLTVVFFIIVALPFVKPVNWQPFLPFGWQGVMTAAALGFFAYGGFDAVT
TAAEETRNPNRDIPLGLILGLVVVASLYVLVSLVLTGVIPYTKLDTPAPVAFALSYLGKRWGGSLVAAGAICGLFTVMMG
AMLGGSRILFALSRDGLLPPVFSRVHATRRTPYVATLIVLTVAVLTGGFLSLGELVELVNIGMLTAYLLTSISILVMRLR
YPEIERPFRVPAVWLVAPVATLGVVALTFSLPGATLVRFAIWFIVGMLIYFGYGIRHSKLANRENN
>Mature_465_residues
ASSILRKKDIATAMEMAAMDQYRLRRELKAMDLFFLVIGITIGGGIFVLPGVMAAEHAGPGVTISFLIGAVVAIFTGLCY
VEFASMVPVAGSAYTYSYIALGEIFAWIIGWDVLLEFTLVCSAVAVGWSGYIVELLKDMGLSLPPAFTTDIAHGGIVNLP
AVFILLVVAYIIYGGISLTGKVNDAIGIIKLLTVVFFIIVALPFVKPVNWQPFLPFGWQGVMTAAALGFFAYGGFDAVTT
AAEETRNPNRDIPLGLILGLVVVASLYVLVSLVLTGVIPYTKLDTPAPVAFALSYLGKRWGGSLVAAGAICGLFTVMMGA
MLGGSRILFALSRDGLLPPVFSRVHATRRTPYVATLIVLTVAVLTGGFLSLGELVELVNIGMLTAYLLTSISILVMRLRY
PEIERPFRVPAVWLVAPVATLGVVALTFSLPGATLVRFAIWFIVGMLIYFGYGIRHSKLANRENN

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=433, Percent_Identity=33.4872979214781, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI258614005, Length=433, Percent_Identity=32.3325635103926, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI258614003, Length=433, Percent_Identity=32.3325635103926, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=32.5635103926097, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI110347453, Length=408, Percent_Identity=34.8039215686275, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=31.4814814814815, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=31.4814814814815, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI181337167, Length=417, Percent_Identity=34.5323741007194, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI187423910, Length=469, Percent_Identity=26.0127931769723, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7657591, Length=469, Percent_Identity=26.0127931769723, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI115648063, Length=424, Percent_Identity=24.7641509433962, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI115648022, Length=424, Percent_Identity=24.7641509433962, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI186910308, Length=403, Percent_Identity=24.5657568238213, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI186910306, Length=403, Percent_Identity=24.5657568238213, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI186910304, Length=403, Percent_Identity=24.5657568238213, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI71979932, Length=402, Percent_Identity=26.865671641791, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI33286428, Length=405, Percent_Identity=25.1851851851852, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7657683, Length=356, Percent_Identity=25.561797752809, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI71999149, Length=409, Percent_Identity=26.4058679706601, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI87081869, Length=469, Percent_Identity=24.9466950959488, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788480, Length=411, Percent_Identity=23.3576642335766, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786602, Length=416, Percent_Identity=22.3557692307692, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786302, Length=413, Percent_Identity=24.2130750605327, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082250, Length=427, Percent_Identity=25.5269320843091, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787768, Length=274, Percent_Identity=24.0875912408759, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786908, Length=331, Percent_Identity=21.4501510574018, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789017, Length=357, Percent_Identity=24.0896358543417, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081708, Length=363, Percent_Identity=22.8650137741047, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786789, Length=424, Percent_Identity=22.4056603773585, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87082023, Length=249, Percent_Identity=25.7028112449799, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=389, Percent_Identity=33.1619537275064, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17531343, Length=421, Percent_Identity=31.353919239905, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17533459, Length=413, Percent_Identity=30.2663438256659, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17540018, Length=427, Percent_Identity=25.0585480093677, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982612, Length=393, Percent_Identity=23.9185750636132, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71982608, Length=393, Percent_Identity=23.9185750636132, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17537453, Length=356, Percent_Identity=23.0337078651685, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=422, Percent_Identity=24.6445497630332, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=395, Percent_Identity=20.5063291139241, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=395, Percent_Identity=20.5063291139241, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71993915, Length=414, Percent_Identity=22.9468599033816, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568033, Length=407, Percent_Identity=24.5700245700246, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71990446, Length=423, Percent_Identity=20.3309692671395, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24667468, Length=419, Percent_Identity=34.6062052505967, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24668806, Length=409, Percent_Identity=35.2078239608802, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI21356285, Length=409, Percent_Identity=35.2078239608802, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24668802, Length=409, Percent_Identity=35.2078239608802, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI221512776, Length=424, Percent_Identity=33.7264150943396, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24666159, Length=424, Percent_Identity=33.7264150943396, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI161077963, Length=406, Percent_Identity=36.9458128078818, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI281366235, Length=422, Percent_Identity=31.9905213270142, Blast_Score=185, Evalue=7e-47,
Organism=Drosophila melanogaster, GI116007820, Length=422, Percent_Identity=31.9905213270142, Blast_Score=185, Evalue=7e-47,
Organism=Drosophila melanogaster, GI116007818, Length=407, Percent_Identity=31.6953316953317, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI85725152, Length=407, Percent_Identity=31.6953316953317, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21357367, Length=433, Percent_Identity=26.3279445727483, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI45550968, Length=405, Percent_Identity=24.4444444444444, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19921172, Length=405, Percent_Identity=24.4444444444444, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221331183, Length=416, Percent_Identity=26.2019230769231, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17647653, Length=416, Percent_Identity=26.2019230769231, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24664379, Length=416, Percent_Identity=26.2019230769231, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24651635, Length=408, Percent_Identity=24.7549019607843, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24651633, Length=408, Percent_Identity=24.7549019607843, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641995, Length=406, Percent_Identity=24.8768472906404, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641993, Length=406, Percent_Identity=24.8768472906404, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49933; Mature: 49802

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
>Mature Secondary Structure 
ASSILRKKDIATAMEMAAMDQYRLRRELKAMDLFFLVIGITIGGGIFVLPGVMAAEHAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCC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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]