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The map label for this gene is fadR [H]

Identifier: 83590682

GI number: 83590682

Start: 1906246

End: 1906878

Strand: Reverse

Name: fadR [H]

Synonym: Moth_1848

Alternate gene names: 83590682

Gene position: 1906878-1906246 (Counterclockwise)

Preceding gene: 83590684

Following gene: 83590681

Centisome position: 72.54

GC content: 59.08

Gene sequence:

>633_bases
TTGGTTTACCGGCGGACAAAAAAGGTGGATCAAAAATTGGAAGCGCGCCTGCAGGCCATTATGCAGGCGGCGCGGGAAGA
ATTCGCCCGGAACGGTTTCTACGGAACCTCGATTAAAGATATCGCCCGCCGGGCGGGGGTGGGCATCGGTACGATTTATT
TATACCTGCGTAATAAAGAAGCCCTCTTTGCCGCCCTGGTCAACGAAGCCTATGAAATGGTCCTGGACCGTATTGCCCGG
GCCCGCAAAAACGCTACCGGCGGGAAGCAAAAGCTCCGGGCCTCTATGGAGGCGGCCCTGGCGGTCTTACAGGAGAACCG
CGACCTGGCGCGGGTAATGCTTGTCCAATCGCCGGCGGGCCACCCGGCAGTGGCGGAACAACTCTACGATTTGCTGCGCC
GTCTGGCCAGGCTGGTGGAGGAAGACGTGCTGGAGGAGATCGAGAGAGGGGAACTACCGCCCCAGGATGCCCATGTCGCG
GCCCTGGCCTTTGTAGGTACCTTTTACCAGGTAGTCATCAGCTGGCTCAAGGAGGGTATCCCGGCCGACCTGACGGCGGC
CGGCAAAGAGCTGATAGCCTATAACCTGCGCGGTTTGGGTTACCCAGTGGAGGGAGTAATTGAGAATGCTTGA

Upstream 100 bases:

>100_bases
ATTGTTCCCGGAAGACATTGACGTCGTCCCCCAAAAGGTTTAAAATCGCTGTTGAAGAATTGAATTACCGTTCATTGTTT
GAAAATTGGAGGAAGAACTT

Downstream 100 bases:

>100_bases
AGAAAAGATCCAGGCAGACATCGGCTTTATCGGCGGCTCGGGCACCTTCAGCCTGAACTTTCCTGACGCCTTAAGGGATC
CCGGGACGGAGGTGCTGGCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MVYRRTKKVDQKLEARLQAIMQAAREEFARNGFYGTSIKDIARRAGVGIGTIYLYLRNKEALFAALVNEAYEMVLDRIAR
ARKNATGGKQKLRASMEAALAVLQENRDLARVMLVQSPAGHPAVAEQLYDLLRRLARLVEEDVLEEIERGELPPQDAHVA
ALAFVGTFYQVVISWLKEGIPADLTAAGKELIAYNLRGLGYPVEGVIENA

Sequences:

>Translated_210_residues
MVYRRTKKVDQKLEARLQAIMQAAREEFARNGFYGTSIKDIARRAGVGIGTIYLYLRNKEALFAALVNEAYEMVLDRIAR
ARKNATGGKQKLRASMEAALAVLQENRDLARVMLVQSPAGHPAVAEQLYDLLRRLARLVEEDVLEEIERGELPPQDAHVA
ALAFVGTFYQVVISWLKEGIPADLTAAGKELIAYNLRGLGYPVEGVIENA
>Mature_210_residues
MVYRRTKKVDQKLEARLQAIMQAAREEFARNGFYGTSIKDIARRAGVGIGTIYLYLRNKEALFAALVNEAYEMVLDRIAR
ARKNATGGKQKLRASMEAALAVLQENRDLARVMLVQSPAGHPAVAEQLYDLLRRLARLVEEDVLEEIERGELPPQDAHVA
ALAFVGTFYQVVISWLKEGIPADLTAAGKELIAYNLRGLGYPVEGVIENA

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23341; Mature: 23341

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00356 HTH_LACI_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYRRTKKVDQKLEARLQAIMQAAREEFARNGFYGTSIKDIARRAGVGIGTIYLYLRNKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHEEEEEECCH
ALFAALVNEAYEMVLDRIARARKNATGGKQKLRASMEAALAVLQENRDLARVMLVQSPAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
HPAVAEQLYDLLRRLARLVEEDVLEEIERGELPPQDAHVAALAFVGTFYQVVISWLKEGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PADLTAAGKELIAYNLRGLGYPVEGVIENA
CCCHHHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MVYRRTKKVDQKLEARLQAIMQAAREEFARNGFYGTSIKDIARRAGVGIGTIYLYLRNKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHEEEEEECCH
ALFAALVNEAYEMVLDRIARARKNATGGKQKLRASMEAALAVLQENRDLARVMLVQSPAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
HPAVAEQLYDLLRRLARLVEEDVLEEIERGELPPQDAHVAALAFVGTFYQVVISWLKEGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PADLTAAGKELIAYNLRGLGYPVEGVIENA
CCCHHHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]