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The map label for this gene is pepQ [H]

Identifier: 83590647

GI number: 83590647

Start: 1872523

End: 1873680

Strand: Reverse

Name: pepQ [H]

Synonym: Moth_1813

Alternate gene names: 83590647

Gene position: 1873680-1872523 (Counterclockwise)

Preceding gene: 83590649

Following gene: 83590641

Centisome position: 71.28

GC content: 63.99

Gene sequence:

>1158_bases
ATGGCAAAGCTGGAATACATAGAATATAAGAATCGCCTGAGGCGTTTCCAGGAGTCCCTGCAAGCTCTGGACCTGGACGG
GGCCCTGGTCTACCAGGCCGCCGACCTGTACTACCTGACAGGAACGGCCCAGAGCTGCCACCTTTTCGTTCCGGCTGCCG
GGGAGCCCCTCCTCCTGGCCTACCGGGATTTTGAGCGGGCACGGGAGGAATCCGCCTGGCAGGTCAGGCCCCTGGGTAGT
TTTAAGGATATCCCAGGTCTCCTGGCGGAGGCCGGGTTGACCGGGCTGCGGCGCCTGGGACTGGAGCTGGACGTCATTCC
CTTAAGCCTTTTCCGGCGCTACGAGGCCCTCTTGCCCGGCGTTCAGTGGGCCGACATCGGCCAGGTCCTGCGACGGCAAC
GAATGGTCAAATCGCCGGCCGAACTGGAGGCCCTGCGGTGGTCCGCCGCCAAACACGCAGAGGTCTTCCGTTACATAACT
GCCAGGATCCGGCCTGGTATGACAGAGCTGGAGATTGCCGCCGAGTTTGAAAGCTATGCCCGCCGCCTGGGCCACCAGGG
CGCCAAGCGCTTCCGGGGTCAGGAGCAGGGCATGATTCCGGGCCTGGTTGCCGCCGGGGCCAACTCCGCCCGGACCTCCT
GCTTCAACCTGCCTCTGGCCGGCCTGGGCCTCTCACCCCTTTACCCTATGGGAGCCAGCCAGCACGTCTGGGAGGAAGGT
GAACCCCTCCTTATCGACTACGCCGGGGTTTACGGCGACTACACCGTCGACCAGACCAGGATCTACCTTGGTAAGGGGGT
ACCGGAAGACTTACGGCAGGCCCAGGAAGTGGCTATGGAGATTGCCAGCCGGGTGGCGGAAGAGGCCCGGCCCGGAGTAA
CGGCCGGCGCCCTCTACGACCTGGCCGTGGCCATGGCGGCCCGCGCTGGTTTGCAGGAGCACTTTATGGGCTACGGCCGG
CAGGTGACTTACATCGGTCACGGCGTCGGCCTGGACCTGAACGAGTGGCCGGTGATAGCCAGGGGGGACAAGACTGTCCT
GGCCGCGGGCATGGTCTTCGCCCTGGAGCCCAAGTTTGTCTTCCCGGGGATGGGCAGCGCCGGGGTGGAGGATACGTATG
TGGTTACTGATAGGGGAGCGGAAAAGTTGACATATTAG

Upstream 100 bases:

>100_bases
TCCTCACAGTATTTACCTAGATGGAATAATCTTGGTAATATAATATGGGGCTGGTAACTCTTGTGTGCAATAACGAGTTT
AGATAAAGGTGGTTGTTTAT

Downstream 100 bases:

>100_bases
GTAACAGTTAGCCGCAGCGTCGTCCGTTGAGCAAGTTTATTAGTTTTAACCAGTTATACAAATATACCGGCAGGATAAAA
CGCTGCCGGACATGTTCCCG

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAKLEYIEYKNRLRRFQESLQALDLDGALVYQAADLYYLTGTAQSCHLFVPAAGEPLLLAYRDFERAREESAWQVRPLGS
FKDIPGLLAEAGLTGLRRLGLELDVIPLSLFRRYEALLPGVQWADIGQVLRRQRMVKSPAELEALRWSAAKHAEVFRYIT
ARIRPGMTELEIAAEFESYARRLGHQGAKRFRGQEQGMIPGLVAAGANSARTSCFNLPLAGLGLSPLYPMGASQHVWEEG
EPLLIDYAGVYGDYTVDQTRIYLGKGVPEDLRQAQEVAMEIASRVAEEARPGVTAGALYDLAVAMAARAGLQEHFMGYGR
QVTYIGHGVGLDLNEWPVIARGDKTVLAAGMVFALEPKFVFPGMGSAGVEDTYVVTDRGAEKLTY

Sequences:

>Translated_385_residues
MAKLEYIEYKNRLRRFQESLQALDLDGALVYQAADLYYLTGTAQSCHLFVPAAGEPLLLAYRDFERAREESAWQVRPLGS
FKDIPGLLAEAGLTGLRRLGLELDVIPLSLFRRYEALLPGVQWADIGQVLRRQRMVKSPAELEALRWSAAKHAEVFRYIT
ARIRPGMTELEIAAEFESYARRLGHQGAKRFRGQEQGMIPGLVAAGANSARTSCFNLPLAGLGLSPLYPMGASQHVWEEG
EPLLIDYAGVYGDYTVDQTRIYLGKGVPEDLRQAQEVAMEIASRVAEEARPGVTAGALYDLAVAMAARAGLQEHFMGYGR
QVTYIGHGVGLDLNEWPVIARGDKTVLAAGMVFALEPKFVFPGMGSAGVEDTYVVTDRGAEKLTY
>Mature_384_residues
AKLEYIEYKNRLRRFQESLQALDLDGALVYQAADLYYLTGTAQSCHLFVPAAGEPLLLAYRDFERAREESAWQVRPLGSF
KDIPGLLAEAGLTGLRRLGLELDVIPLSLFRRYEALLPGVQWADIGQVLRRQRMVKSPAELEALRWSAAKHAEVFRYITA
RIRPGMTELEIAAEFESYARRLGHQGAKRFRGQEQGMIPGLVAAGANSARTSCFNLPLAGLGLSPLYPMGASQHVWEEGE
PLLIDYAGVYGDYTVDQTRIYLGKGVPEDLRQAQEVAMEIASRVAEEARPGVTAGALYDLAVAMAARAGLQEHFMGYGRQ
VTYIGHGVGLDLNEWPVIARGDKTVLAAGMVFALEPKFVFPGMGSAGVEDTYVVTDRGAEKLTY

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=294, Percent_Identity=27.891156462585, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 42435; Mature: 42304

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLEYIEYKNRLRRFQESLQALDLDGALVYQAADLYYLTGTAQSCHLFVPAAGEPLLLA
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCEEEEEECCCCCEEEE
YRDFERAREESAWQVRPLGSFKDIPGLLAEAGLTGLRRLGLELDVIPLSLFRRYEALLPG
EHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCC
VQWADIGQVLRRQRMVKSPAELEALRWSAAKHAEVFRYITARIRPGMTELEIAAEFESYA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRLGHQGAKRFRGQEQGMIPGLVAAGANSARTSCFNLPLAGLGLSPLYPMGASQHVWEEG
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHCCC
EPLLIDYAGVYGDYTVDQTRIYLGKGVPEDLRQAQEVAMEIASRVAEEARPGVTAGALYD
CEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LAVAMAARAGLQEHFMGYGRQVTYIGHGVGLDLNEWPVIARGDKTVLAAGMVFALEPKFV
HHHHHHHHHCHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCCEEEECCEEEEECCCEE
FPGMGSAGVEDTYVVTDRGAEKLTY
CCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
AKLEYIEYKNRLRRFQESLQALDLDGALVYQAADLYYLTGTAQSCHLFVPAAGEPLLLA
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCEEEEEECCCCCEEEE
YRDFERAREESAWQVRPLGSFKDIPGLLAEAGLTGLRRLGLELDVIPLSLFRRYEALLPG
EHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCC
VQWADIGQVLRRQRMVKSPAELEALRWSAAKHAEVFRYITARIRPGMTELEIAAEFESYA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRLGHQGAKRFRGQEQGMIPGLVAAGANSARTSCFNLPLAGLGLSPLYPMGASQHVWEEG
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHCCC
EPLLIDYAGVYGDYTVDQTRIYLGKGVPEDLRQAQEVAMEIASRVAEEARPGVTAGALYD
CEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LAVAMAARAGLQEHFMGYGRQVTYIGHGVGLDLNEWPVIARGDKTVLAAGMVFALEPKFV
HHHHHHHHHCHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCCEEEECCEEEEECCCEE
FPGMGSAGVEDTYVVTDRGAEKLTY
CCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]