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The map label for this gene is patA [H]

Identifier: 83590620

GI number: 83590620

Start: 1837980

End: 1839371

Strand: Reverse

Name: patA [H]

Synonym: Moth_1785

Alternate gene names: 83590620

Gene position: 1839371-1837980 (Counterclockwise)

Preceding gene: 83590621

Following gene: 83590619

Centisome position: 69.97

GC content: 60.13

Gene sequence:

>1392_bases
TTGACAGGAGAGAAAATAATCAGCCTGGAGACGGCCCTGCAGGCCGGCCGCCAGGAAACCAGGGATCTCTACCGTCGTTA
TATCAATCCTGGCCTGGCCACGATGCTGGCCCTGCTGGACTTCGACAAGGCCTTTGTCCGGGCCGAGGGAATGGCGGTCT
GGGATAAGGACGGTAAACGCTACCTTGATTTCCTGGGCGGCTACGGCGCCCTGAACCTGGGCCATAACCCGCCGGAGGTG
CTGGCGGCAGTCAAAGAGGCCATGGGCCGCCCCAACCTCCTCCAGGCTTCCCTCAATCCCCTGGCGGCAGCCCTGGCCCA
TAACCTGGCCCAGGTTACTCCGGGCGACCTGGAGCGGGTTTTTTTTAGCAACAGCGGGACTGAAACGGTGGAGGGCGCCC
TGAAACTCGCCCGGGCGTCTACAGGTAGGGAGAAGATTATTTACTGCCAGAACTCCTTTCATGGCAAGAGTTTCGGTTCT
TTATCGGTCACCGGGCGCCAGAAATATCAGCGTCCCTTCGGTCCCCTGTTACCTGGCTGTGAGGCCGTCCCCTATGACGA
CCTGGAAGCCCTGGAGGCCAAACTCTCCCGCCGGGACGCGGCCGCCTTTATCGTCGAACCCATCCAGGGCGAAGGCGGGG
TTATCGTTCCCCATGACGGTTACCTTAAAGGGGCGCGGGAACTCTGCGACCGCTACGGCAGCCTGCTGATTATCGATGAG
ATCCAGACGGGCTTTGGCCGGACTGGTTATCTATTTGCCTGCGAGCATGAGGGCGTGGTCCCGGATATTATGTGCCTGGC
CAAGTCCCTGGGCGGCGGCGTCATGCCAATCGGCGCCTATATTGCCCGGCCGGCAGTATGGGATCGGGCTTACGGCGGTA
TGGACAAAGCCCTGCTCCACACCTCCACCTTCGGCGGCAACAGCCTGGCCACAGCCGCCGGCCTGGCAGCCCTGCAGAGC
ATCCTGGATCAGGACCTGGCCGGCCGGGCGGCTGCTATGGGGCGTTATTTCCTGGAGAGGTTACGGCAGCTAAAGGAAAA
GTACGATCTAATTAAAGACGTCCGCGGCCGCGGCCTGATCATCGGCCTGGAATTTAACCAGCCGGTGGGAGGGCTGTTAG
ATAAACTGACCCGGGGCAAGGTTAACGAACTGGCAGGAGAGTACTTCGGTTCCCTGGTAGCCGGCGAACTCATGAACAAG
TACCAGGTGATAACAGCTTACACCCTGAACAACCCCAACGTCATCCGCCTGGAGCCGCCCCTGATCGTCGGTGAGGAAGA
GATTGACCATGTAGTGAATGCCCTCGAAGCCGTGCTTCGTGGCCATGGTTTCCTGGGGGTAACCTTAAGCAGCACCCGGA
CCGCCCTGGGTTCCCTCTTTAAACGTAAATAG

Upstream 100 bases:

>100_bases
CCTTAAAGGGAGAGCCCTTTAGGGTCAATTATTTTTTGCACCCTTAAAAGGGCCGACCCCTGTTTGGTTAAATATTTTTG
CGGAAAGGTAAGTGGGAGGA

Downstream 100 bases:

>100_bases
GGCATAAATACTTGCTATTCCCGGCAGACTAAATAAAAAATCAGCCGGGAGGTGCGAGTGCTTTTTAAACTATGCCTGAA
GACAACGTCATCGTTTATAC

Product: aminotransferase

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTGEKIISLETALQAGRQETRDLYRRYINPGLATMLALLDFDKAFVRAEGMAVWDKDGKRYLDFLGGYGALNLGHNPPEV
LAAVKEAMGRPNLLQASLNPLAAALAHNLAQVTPGDLERVFFSNSGTETVEGALKLARASTGREKIIYCQNSFHGKSFGS
LSVTGRQKYQRPFGPLLPGCEAVPYDDLEALEAKLSRRDAAAFIVEPIQGEGGVIVPHDGYLKGARELCDRYGSLLIIDE
IQTGFGRTGYLFACEHEGVVPDIMCLAKSLGGGVMPIGAYIARPAVWDRAYGGMDKALLHTSTFGGNSLATAAGLAALQS
ILDQDLAGRAAAMGRYFLERLRQLKEKYDLIKDVRGRGLIIGLEFNQPVGGLLDKLTRGKVNELAGEYFGSLVAGELMNK
YQVITAYTLNNPNVIRLEPPLIVGEEEIDHVVNALEAVLRGHGFLGVTLSSTRTALGSLFKRK

Sequences:

>Translated_463_residues
MTGEKIISLETALQAGRQETRDLYRRYINPGLATMLALLDFDKAFVRAEGMAVWDKDGKRYLDFLGGYGALNLGHNPPEV
LAAVKEAMGRPNLLQASLNPLAAALAHNLAQVTPGDLERVFFSNSGTETVEGALKLARASTGREKIIYCQNSFHGKSFGS
LSVTGRQKYQRPFGPLLPGCEAVPYDDLEALEAKLSRRDAAAFIVEPIQGEGGVIVPHDGYLKGARELCDRYGSLLIIDE
IQTGFGRTGYLFACEHEGVVPDIMCLAKSLGGGVMPIGAYIARPAVWDRAYGGMDKALLHTSTFGGNSLATAAGLAALQS
ILDQDLAGRAAAMGRYFLERLRQLKEKYDLIKDVRGRGLIIGLEFNQPVGGLLDKLTRGKVNELAGEYFGSLVAGELMNK
YQVITAYTLNNPNVIRLEPPLIVGEEEIDHVVNALEAVLRGHGFLGVTLSSTRTALGSLFKRK
>Mature_462_residues
TGEKIISLETALQAGRQETRDLYRRYINPGLATMLALLDFDKAFVRAEGMAVWDKDGKRYLDFLGGYGALNLGHNPPEVL
AAVKEAMGRPNLLQASLNPLAAALAHNLAQVTPGDLERVFFSNSGTETVEGALKLARASTGREKIIYCQNSFHGKSFGSL
SVTGRQKYQRPFGPLLPGCEAVPYDDLEALEAKLSRRDAAAFIVEPIQGEGGVIVPHDGYLKGARELCDRYGSLLIIDEI
QTGFGRTGYLFACEHEGVVPDIMCLAKSLGGGVMPIGAYIARPAVWDRAYGGMDKALLHTSTFGGNSLATAAGLAALQSI
LDQDLAGRAAAMGRYFLERLRQLKEKYDLIKDVRGRGLIIGLEFNQPVGGLLDKLTRGKVNELAGEYFGSLVAGELMNKY
QVITAYTLNNPNVIRLEPPLIVGEEEIDHVVNALEAVLRGHGFLGVTLSSTRTALGSLFKRK

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=418, Percent_Identity=31.5789473684211, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI13994255, Length=478, Percent_Identity=28.6610878661088, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI284507298, Length=337, Percent_Identity=32.6409495548961, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI37574042, Length=450, Percent_Identity=28.8888888888889, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI226442705, Length=453, Percent_Identity=28.6975717439294, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=29.7709923664122, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=27.3809523809524, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI145693181, Length=448, Percent_Identity=42.4107142857143, Blast_Score=336, Evalue=1e-93,
Organism=Escherichia coli, GI1789759, Length=391, Percent_Identity=37.0843989769821, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1788044, Length=390, Percent_Identity=36.9230769230769, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789016, Length=341, Percent_Identity=36.0703812316716, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787560, Length=412, Percent_Identity=33.9805825242718, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786991, Length=347, Percent_Identity=34.8703170028818, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786349, Length=284, Percent_Identity=36.2676056338028, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=401, Percent_Identity=32.6683291770574, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI25144274, Length=392, Percent_Identity=30.3571428571429, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=29.7727272727273, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=463, Percent_Identity=26.133909287257, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17541228, Length=396, Percent_Identity=25.7575757575758, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=155, Percent_Identity=31.6129032258064, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=34.4827586206897, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324432, Length=354, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324386, Length=355, Percent_Identity=28.169014084507, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=393, Percent_Identity=24.1730279898219, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=33.4134615384615, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI161085790, Length=460, Percent_Identity=31.0869565217391, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI28574759, Length=453, Percent_Identity=31.1258278145695, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356575, Length=450, Percent_Identity=29.5555555555556, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 50130; Mature: 49999

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEKIISLETALQAGRQETRDLYRRYINPGLATMLALLDFDKAFVRAEGMAVWDKDGKR
CCCCCEEHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHH
YLDFLGGYGALNLGHNPPEVLAAVKEAMGRPNLLQASLNPLAAALAHNLAQVTPGDLERV
HHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FFSNSGTETVEGALKLARASTGREKIIYCQNSFHGKSFGSLSVTGRQKYQRPFGPLLPGC
EECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCHHHHCCCCCCCCCCC
EAVPYDDLEALEAKLSRRDAAAFIVEPIQGEGGVIVPHDGYLKGARELCDRYGSLLIIDE
CCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCEEEEEC
IQTGFGRTGYLFACEHEGVVPDIMCLAKSLGGGVMPIGAYIARPAVWDRAYGGMDKALLH
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHCCCHHHHHE
TSTFGGNSLATAAGLAALQSILDQDLAGRAAAMGRYFLERLRQLKEKYDLIKDVRGRGLI
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IGLEFNQPVGGLLDKLTRGKVNELAGEYFGSLVAGELMNKYQVITAYTLNNPNVIRLEPP
EEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEECCC
LIVGEEEIDHVVNALEAVLRGHGFLGVTLSSTRTALGSLFKRK
EEECHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure 
TGEKIISLETALQAGRQETRDLYRRYINPGLATMLALLDFDKAFVRAEGMAVWDKDGKR
CCCCEEHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHH
YLDFLGGYGALNLGHNPPEVLAAVKEAMGRPNLLQASLNPLAAALAHNLAQVTPGDLERV
HHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FFSNSGTETVEGALKLARASTGREKIIYCQNSFHGKSFGSLSVTGRQKYQRPFGPLLPGC
EECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCHHHHCCCCCCCCCCC
EAVPYDDLEALEAKLSRRDAAAFIVEPIQGEGGVIVPHDGYLKGARELCDRYGSLLIIDE
CCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCEEEEEC
IQTGFGRTGYLFACEHEGVVPDIMCLAKSLGGGVMPIGAYIARPAVWDRAYGGMDKALLH
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHCCCHHHHHE
TSTFGGNSLATAAGLAALQSILDQDLAGRAAAMGRYFLERLRQLKEKYDLIKDVRGRGLI
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IGLEFNQPVGGLLDKLTRGKVNELAGEYFGSLVAGELMNKYQVITAYTLNNPNVIRLEPP
EEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEECCC
LIVGEEEIDHVVNALEAVLRGHGFLGVTLSSTRTALGSLFKRK
EEECHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA