Click here to switch to the map view.

The map label for this gene is nadC [H]

Identifier: 83590614

GI number: 83590614

Start: 1834084

End: 1834887

Strand: Reverse

Name: nadC [H]

Synonym: Moth_1779

Alternate gene names: 83590614

Gene position: 1834887-1834084 (Counterclockwise)

Preceding gene: 83590615

Following gene: 83590613

Centisome position: 69.8

GC content: 64.3

Gene sequence:

>804_bases
ATGCCAGTGGAGCTTAGGGATTTCCTCTTTGCCCCCCTGGAGGGGAAAAAATTCATCTTTAAGATAACGTCCCGGGAAAA
AGGGATCTTTTCCGGGGCTGCCCGGTTGGAGCAACAGGCCAGGGAGCTGGGCCTTGAGTTTACGATCCTGGCCTCCGAAG
GAGCGCCCCTGGAACCCGGAAGCTGTATCCTTCGGGGCCAAGGCGGGGCGGAGGAGGTCATCCGGGCCGAAGAAATGCTC
CTGGGTGCCATTGGTAAACCCTCGGGGGTGGCTACGGCGGCGGCCGATTTTGTCCGCCGGGCCGGGGGTCGCATCAAAGT
CGTCTGCGGCGCCTGGAAGAAGGTAGCCCCGGAGGTAAGGTCCGACCTGCGCCGGGCCATCGCCACTGGCGGGGCGGGGG
TACGCATTACCGACCGGCCCTTTATCTACCTGGATAAAAACTATGTCCGCCTCCTGGGCGGTGTCGGCCCGGCTGTTGCC
CGGGCCCGGGCCTATGATCCGGAACGGGTAATTGCCGTGCAGCTGCGTGGCGAACTCCAGCCTGTGGCAGTCGAAGCCGC
AGTAGCCGCAGAGGCCGGGGCCGGCATCCTGATGGTGGATACCGGGAACCTCCGGGACCTGAAGGCGGCAGTGACGGCGG
CCAGAACCGGAGGCTGGCGGGAACAGGTCCAGATAGCCTTTGCCGGTGGTGTCACCCCGGCCGGATTGGAGGCCGTTATC
GCCGCCGGCGCCGACATTGTGGACGTAGGCCGGGCCATCATCGATGCCCCCCTGTTAGATCTGAGCATGGATGTAGCAGA
GTAG

Upstream 100 bases:

>100_bases
CGGATGGACGGAGAGAGGCTGCAGCTGGCGATAGATCGTATTACCCGGACGGCGGCCGAGATTTCGGCCGGGTTGGGTTA
CCGGCCCGTCGTGGAGAGTG

Downstream 100 bases:

>100_bases
TTTAACTAGATGAAACCTAATTAATTCCCTATAGATTCCAACTAAAGCAAATTATATCTCGGTATCCGTGACGCAGGAAA
GGAGGGAAAACTATGGAGTG

Product: nicotinate-nucleotide pyrophosphorylase

Products: NA

Alternate protein names: Quinolinate phosphoribosyltransferase [decarboxylating]; QAPRTase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPVELRDFLFAPLEGKKFIFKITSREKGIFSGAARLEQQARELGLEFTILASEGAPLEPGSCILRGQGGAEEVIRAEEML
LGAIGKPSGVATAAADFVRRAGGRIKVVCGAWKKVAPEVRSDLRRAIATGGAGVRITDRPFIYLDKNYVRLLGGVGPAVA
RARAYDPERVIAVQLRGELQPVAVEAAVAAEAGAGILMVDTGNLRDLKAAVTAARTGGWREQVQIAFAGGVTPAGLEAVI
AAGADIVDVGRAIIDAPLLDLSMDVAE

Sequences:

>Translated_267_residues
MPVELRDFLFAPLEGKKFIFKITSREKGIFSGAARLEQQARELGLEFTILASEGAPLEPGSCILRGQGGAEEVIRAEEML
LGAIGKPSGVATAAADFVRRAGGRIKVVCGAWKKVAPEVRSDLRRAIATGGAGVRITDRPFIYLDKNYVRLLGGVGPAVA
RARAYDPERVIAVQLRGELQPVAVEAAVAAEAGAGILMVDTGNLRDLKAAVTAARTGGWREQVQIAFAGGVTPAGLEAVI
AAGADIVDVGRAIIDAPLLDLSMDVAE
>Mature_266_residues
PVELRDFLFAPLEGKKFIFKITSREKGIFSGAARLEQQARELGLEFTILASEGAPLEPGSCILRGQGGAEEVIRAEEMLL
GAIGKPSGVATAAADFVRRAGGRIKVVCGAWKKVAPEVRSDLRRAIATGGAGVRITDRPFIYLDKNYVRLLGGVGPAVAR
ARAYDPERVIAVQLRGELQPVAVEAAVAAEAGAGILMVDTGNLRDLKAAVTAARTGGWREQVQIAFAGGVTPAGLEAVIA
AGADIVDVGRAIIDAPLLDLSMDVAE

Specific function: Involved in the catabolism of quinolinic acid (QA) [H]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004393
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: =2.4.2.19 [H]

Molecular weight: Translated: 27954; Mature: 27822

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVELRDFLFAPLEGKKFIFKITSREKGIFSGAARLEQQARELGLEFTILASEGAPLEPG
CCCCHHHHEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
SCILRGQGGAEEVIRAEEMLLGAIGKPSGVATAAADFVRRAGGRIKVVCGAWKKVAPEVR
CEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
SDLRRAIATGGAGVRITDRPFIYLDKNYVRLLGGVGPAVARARAYDPERVIAVQLRGELQ
HHHHHHHHCCCCCEEECCCCEEEECCHHHHHHCCCCHHHHHHHCCCCCEEEEEEECCCCC
PVAVEAAVAAEAGAGILMVDTGNLRDLKAAVTAARTGGWREQVQIAFAGGVTPAGLEAVI
CEEEHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHEEEEEEECCCCCHHHHHHH
AAGADIVDVGRAIIDAPLLDLSMDVAE
HCCCCHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
PVELRDFLFAPLEGKKFIFKITSREKGIFSGAARLEQQARELGLEFTILASEGAPLEPG
CCCHHHHEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
SCILRGQGGAEEVIRAEEMLLGAIGKPSGVATAAADFVRRAGGRIKVVCGAWKKVAPEVR
CEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
SDLRRAIATGGAGVRITDRPFIYLDKNYVRLLGGVGPAVARARAYDPERVIAVQLRGELQ
HHHHHHHHCCCCCEEECCCCEEEECCHHHHHHCCCCHHHHHHHCCCCCEEEEEEECCCCC
PVAVEAAVAAEAGAGILMVDTGNLRDLKAAVTAARTGGWREQVQIAFAGGVTPAGLEAVI
CEEEHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHEEEEEEECCCCCHHHHHHH
AAGADIVDVGRAIIDAPLLDLSMDVAE
HCCCCHHHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]