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The map label for this gene is pheS

Identifier: 83590586

GI number: 83590586

Start: 1805870

End: 1806892

Strand: Reverse

Name: pheS

Synonym: Moth_1751

Alternate gene names: 83590586

Gene position: 1806892-1805870 (Counterclockwise)

Preceding gene: 83590587

Following gene: 83590585

Centisome position: 68.73

GC content: 59.63

Gene sequence:

>1023_bases
ATGTTAGAAGTTATCGCCAAAATTCGGGAGGAAGCCCTGGCCCGGGTGGCAGCGGCCACCAGCAGCGAGGAACTGGAGGC
CTTACGGGTCCGGTACCTGGGAAAAAAGGGTGAACTGACCCGGGTTTTACGGGGGATGGGTAAACTTCCGCCTGAAGAGC
GGCCCCGGGTAGGACAGATGGCCAACAAGGTACGGGAAGAGCTGGAAGGGGCTCTGAAAGAACACCGGGAGAATCTCTCC
CGCCGCGAACAGGCGGAGCGCTTGCGGGCGGAAGCCCTTGATGTGACCCTGCCGGGACGTCCGGTTACCAGGGGCAACCG
TCACCCCCTTTATCAGATATTGAACGAAATCAAGGCCGTTTTTATCGGCCTGGGGTTTGACGTCGCCGAGGGGCCGGAGG
TGGAGAGCGACTACTATAACTTTGAGGCCCTGAACTTACCCAAGGAGCACCCGGCGCGGGATATGCAGGATTCCTTTTAC
ATTACCGAAGACGTACTCCTGCGTACCCATACCTCCCCGGTACAAGTGAGGGTGATGGAAGCGCGGCATCCCCAACTGCC
AATCCGTATTATTGCGCCGGGTAAAGTCTACCGGCGCGACGATGACGCCACCCACTCCCCCTTGTTCCACCAGGTGGAGG
GCCTGCTGGTGGACCGGCGGGTGACCTTCGGCGACCTTAAAGGCACCTTGATGGCTTTTTTAAAGCAGATGTTCGGCGAA
CAGGTCCGGGTGCGTTTCCGGCCCAGCTATTTCCCCTTCACCGAGCCCAGCGCGGAAGTAGATATGTCCTGCGTCATGTG
CGGCGGCAGCGGCTGTCGTGTCTGTTCCCACACCGGCTGGCTGGAGATCCTTGGCTGCGGTATGGTTCACCCTAAGGTTT
TAAGCATGTCCGGCTACGACCCGGAGGAGGTCAGCGGCTTTGCCTTTGGCCTGGGCGTGGAGCGGGTGGCCATGCTGAAG
TACGGCATCGACGACCTGCGCCTCTTCTATGAAAACGACCTGCGCTTCCTGCGGCAGTTTTAA

Upstream 100 bases:

>100_bases
GCATGATGGTGCCGGGTAACTTGGGGTGGTTTGAGGATGTTATTAGCTTTCGTCCCGAAGGGGCGAAGGCTTTTTATTTT
GTCAGAACGAGGTGACCTCA

Downstream 100 bases:

>100_bases
AGGAGTGAATGCCTTTGCGAGTCCCGTATAAATGGCTACAGCAATACGTCGACGTCACCCTGCCGCCTGCAGAGCTGGCC
GACAAGCTCACCATGGCCGG

Product: phenylalanyl-tRNA synthetase, alpha subunit

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLEVIAKIREEALARVAAATSSEELEALRVRYLGKKGELTRVLRGMGKLPPEERPRVGQMANKVREELEGALKEHRENLS
RREQAERLRAEALDVTLPGRPVTRGNRHPLYQILNEIKAVFIGLGFDVAEGPEVESDYYNFEALNLPKEHPARDMQDSFY
ITEDVLLRTHTSPVQVRVMEARHPQLPIRIIAPGKVYRRDDDATHSPLFHQVEGLLVDRRVTFGDLKGTLMAFLKQMFGE
QVRVRFRPSYFPFTEPSAEVDMSCVMCGGSGCRVCSHTGWLEILGCGMVHPKVLSMSGYDPEEVSGFAFGLGVERVAMLK
YGIDDLRLFYENDLRFLRQF

Sequences:

>Translated_340_residues
MLEVIAKIREEALARVAAATSSEELEALRVRYLGKKGELTRVLRGMGKLPPEERPRVGQMANKVREELEGALKEHRENLS
RREQAERLRAEALDVTLPGRPVTRGNRHPLYQILNEIKAVFIGLGFDVAEGPEVESDYYNFEALNLPKEHPARDMQDSFY
ITEDVLLRTHTSPVQVRVMEARHPQLPIRIIAPGKVYRRDDDATHSPLFHQVEGLLVDRRVTFGDLKGTLMAFLKQMFGE
QVRVRFRPSYFPFTEPSAEVDMSCVMCGGSGCRVCSHTGWLEILGCGMVHPKVLSMSGYDPEEVSGFAFGLGVERVAMLK
YGIDDLRLFYENDLRFLRQF
>Mature_340_residues
MLEVIAKIREEALARVAAATSSEELEALRVRYLGKKGELTRVLRGMGKLPPEERPRVGQMANKVREELEGALKEHRENLS
RREQAERLRAEALDVTLPGRPVTRGNRHPLYQILNEIKAVFIGLGFDVAEGPEVESDYYNFEALNLPKEHPARDMQDSFY
ITEDVLLRTHTSPVQVRVMEARHPQLPIRIIAPGKVYRRDDDATHSPLFHQVEGLLVDRRVTFGDLKGTLMAFLKQMFGE
QVRVRFRPSYFPFTEPSAEVDMSCVMCGGSGCRVCSHTGWLEILGCGMVHPKVLSMSGYDPEEVSGFAFGLGVERVAMLK
YGIDDLRLFYENDLRFLRQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5729820, Length=291, Percent_Identity=31.6151202749141, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI4758340, Length=270, Percent_Identity=30.7407407407407, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1788007, Length=336, Percent_Identity=51.7857142857143, Blast_Score=356, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17508957, Length=268, Percent_Identity=31.3432835820896, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32563657, Length=271, Percent_Identity=30.9963099630996, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI32566635, Length=278, Percent_Identity=31.6546762589928, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321087, Length=287, Percent_Identity=29.616724738676, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6325304, Length=279, Percent_Identity=30.1075268817204, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18858079, Length=290, Percent_Identity=32.0689655172414, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI17137424, Length=250, Percent_Identity=30.4, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_MOOTA (Q2RHN7)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430595.1
- ProteinModelPortal:   Q2RHN7
- SMR:   Q2RHN7
- STRING:   Q2RHN7
- GeneID:   3832896
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1751
- NMPDR:   fig|264732.9.peg.1758
- eggNOG:   COG0016
- HOGENOM:   HBG284353
- OMA:   FRASYFP
- PhylomeDB:   Q2RHN7
- BioCyc:   MTHE264732:MOTH_1751-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38650; Mature: 38650

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVIAKIREEALARVAAATSSEELEALRVRYLGKKGELTRVLRGMGKLPPEERPRVGQM
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHH
ANKVREELEGALKEHRENLSRREQAERLRAEALDVTLPGRPVTRGNRHPLYQILNEIKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHH
FIGLGFDVAEGPEVESDYYNFEALNLPKEHPARDMQDSFYITEDVLLRTHTSPVQVRVME
HHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHEECCCCEEEEEEE
ARHPQLPIRIIAPGKVYRRDDDATHSPLFHQVEGLLVDRRVTFGDLKGTLMAFLKQMFGE
CCCCCCCEEEECCCCEEECCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCH
QVRVRFRPSYFPFTEPSAEVDMSCVMCGGSGCRVCSHTGWLEILGCGMVHPKVLSMSGYD
HEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCC
PEEVSGFAFGLGVERVAMLKYGIDDLRLFYENDLRFLRQF
HHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEVIAKIREEALARVAAATSSEELEALRVRYLGKKGELTRVLRGMGKLPPEERPRVGQM
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHH
ANKVREELEGALKEHRENLSRREQAERLRAEALDVTLPGRPVTRGNRHPLYQILNEIKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHH
FIGLGFDVAEGPEVESDYYNFEALNLPKEHPARDMQDSFYITEDVLLRTHTSPVQVRVME
HHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHEECCCCEEEEEEE
ARHPQLPIRIIAPGKVYRRDDDATHSPLFHQVEGLLVDRRVTFGDLKGTLMAFLKQMFGE
CCCCCCCEEEECCCCEEECCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCH
QVRVRFRPSYFPFTEPSAEVDMSCVMCGGSGCRVCSHTGWLEILGCGMVHPKVLSMSGYD
HEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCC
PEEVSGFAFGLGVERVAMLKYGIDDLRLFYENDLRFLRQF
HHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA