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The map label for this gene is atoC [H]

Identifier: 83590549

GI number: 83590549

Start: 1754916

End: 1757162

Strand: Reverse

Name: atoC [H]

Synonym: Moth_1713

Alternate gene names: 83590549

Gene position: 1757162-1754916 (Counterclockwise)

Preceding gene: 83590550

Following gene: 83590548

Centisome position: 66.84

GC content: 59.77

Gene sequence:

>2247_bases
GTGCGGGAAATAGTGAAAACAATCACAGGCAAATGCCGGATGTGTTATGCTTGCATCCGCAACTGCCCGGTCAAGGCGAT
CAAGGTAGTCGACGGCCAGGCCCGGGTGGTACCGGAGCTTTGTATCGCCTGCGGCCACTGCGTCCAGGTCTGTGCCCAGG
GAGCCAAGCTGGTCGAGCGGGAAATAGACAAAGTAGAGGAATTCCTGGCTGCCGGCCGGGTCATAGCCTGCCTGGCGCCT
TCTTTTGTCGCGGAATTTCACCCCGCCTGGCCCGGCCAGGTGGTGGCGGCCCTGCGGAAGCTGGGTTTTGACGAGGTTTA
TGAAGTGGCTTACGGCGCCCATCTGGTTACCCTGGAGTATCAAAAGTACCTCCAGGAAGCCGGCGACCGCCAGGGGCTCA
TCAGCACCCCATGCCCGGCGATAGTCAACCTGGTGACCAAATACTACCCCCGCCTGCTGCCCCAGCTGGTGCCGGTGGTA
TCGCCCATGATCGCCCTGGGACGCTACCTGAAAGCCCGCAAGGGTCCCGATGTCCGCCTGGTCTTCATTGGTCCCTGCGT
GGCCAAGAAAGGAGAGGCCAGGGAGGAAGAAGTAGCCGGGGCGATTGACGCCGTCCTGACCTTTCTGGAGCTAAAGGAGA
TGCTGGTCGCCAGGGAGATCGACATTAATCTCTGCGGTAACAGCGATTTCGATAATGACCCGGCCTATCTGGGCCGCCTC
TACCCCGTCGGGGGCGGCCTCTTACGTAGCGCCGGCATCGATGCCGATATCCTGACCAACCAGGTCCTGGTAGTTGAAGG
CCGTGAAGACTGCCTGGATTTTTTAAAAGCAGTAAACGAGGGCAAGATGGTGCCTCAGATGGCTGATATGCTCTTCTGCA
AGGGGTGCATCAACGGCCCCATGCAGGAAAACGATTTTTCGCCCTACCGGCGGCGGAAGATTGTGGCCGAATTTACCCGC
CAGGGATTGCAAAATACCCGTCCCCAGCCCCTGGATCTCACAGGGATAAACTTGCGCCGGGAGTTTCATGATCAGAGCGT
TTTCTTTCCCCGGCCCAGCGAGGCGGATATCCGGGCCATCCTGGCAGAACTGGGTAAGTATACCCCGGAGGACGAGCTCA
ATTGCGGTGCCTGTGGCTATCCCTCCTGCCGGGAGAAGGCCGTTGCCGTTTATCACGGCCTGGCGGAGAATCGCATGTGC
CTGCCCTACTTCATTGCCCAGCTGGAAAAGAGCAACTTCCACCTGCGCCAGGAGCTTAAAGCCTTCCAGGGCAAGTTTGG
CCAGCTGGTGGGCAACAGTGCAGCCATGCAGGAGGTCTACCGCCTGATAGAGAAGGTAGCTAAAACCGATGCCACCGTCC
TCATCCGGGGGGAGAGCGGTACCGGCAAGGAGCTGGTGGCTAGGGCCATACATTATCACAGCCGCCGGAGCGAGGCGCCC
TTCGTCAGCATCAACTGCGCCGCCCTGCCGGAAACCTTGCTGGAGAGCGAGCTCTTCGGCCATGCCCGGGGCGCCTTTAC
CGGGGCGGTCACGGCTAAGAAAGGACTCTTTGAGGAGGCCAACGAAGGCACCATTTTCCTGGATGAAATCGGCGATATCA
GCCTGGGACTCCAGAGCAAGCTCCTGCGCGTCCTCCAGGAAGGGGAATTCTTACGGGTGGGAGAGACCAGGCCGACCAGG
GTGAACGTCCGCGTCCTGGCGGCCACCAACCGGGACCTGGAGAAGGCCGTCAAGGATGGCGCCTTCCGGCCCGAGCTCCT
TTATCGCCTCAACGTCATTACCATCTGGCTGCCGCCCTTGCGGGAACGGCGGGATGATATCCCCCTGCTGGCCCGTCACT
TCCTGGAAAAATCCTGCCAGCGCCTGGGTAAAGAAGTCAATGGCTTCACCCACGAGGCCATGGACGCCCTGATACGGGCC
GACTGGCCGGGCAATGTTCGGGAACTGGAGAACGTCATCGAGCGGGCGGTTATTTTGACCGAGAGTAAGAGAATCGAGCT
GGGCGATTTACCGCGGCAGTTCCGTAACATGGCCGCCGGGGCTTCCGGCTGGGCCTTCACCCGGGGCATGAGTTTTAAAG
AGGCTGTGGCCGCCTACGAATCGCGCCTTATTCTGCAGGCTCTGGAGGAGAGCCAGGGGGTCCAGGCCCGGGCGGCAGAG
ATCCTGGGCCTGAAGCGGAGCACTTTGAATGAGATGATAAAACGCTATAATTTAATGGGCCGCAAAAATGGTGGTACAAA
TAAATGA

Upstream 100 bases:

>100_bases
TTAAGGGCCATCCACATCCGGTCCGGAAATTCGTCTCCCCATCCAGATAGATGTATTGTATAATAGAGTTTAGGAAAAAT
AGTGCGGCGAGGGATGAATT

Downstream 100 bases:

>100_bases
ACGCTGTACAAAAATATGAATAGCACGGAAACGGCCAACTATCAGGATTAAGACCAATTCCATTCAAAAAAATGTATAGA
AGAAAACAGGCATGGGCTTG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 748; Mature: 748

Protein sequence:

>748_residues
MREIVKTITGKCRMCYACIRNCPVKAIKVVDGQARVVPELCIACGHCVQVCAQGAKLVEREIDKVEEFLAAGRVIACLAP
SFVAEFHPAWPGQVVAALRKLGFDEVYEVAYGAHLVTLEYQKYLQEAGDRQGLISTPCPAIVNLVTKYYPRLLPQLVPVV
SPMIALGRYLKARKGPDVRLVFIGPCVAKKGEAREEEVAGAIDAVLTFLELKEMLVAREIDINLCGNSDFDNDPAYLGRL
YPVGGGLLRSAGIDADILTNQVLVVEGREDCLDFLKAVNEGKMVPQMADMLFCKGCINGPMQENDFSPYRRRKIVAEFTR
QGLQNTRPQPLDLTGINLRREFHDQSVFFPRPSEADIRAILAELGKYTPEDELNCGACGYPSCREKAVAVYHGLAENRMC
LPYFIAQLEKSNFHLRQELKAFQGKFGQLVGNSAAMQEVYRLIEKVAKTDATVLIRGESGTGKELVARAIHYHSRRSEAP
FVSINCAALPETLLESELFGHARGAFTGAVTAKKGLFEEANEGTIFLDEIGDISLGLQSKLLRVLQEGEFLRVGETRPTR
VNVRVLAATNRDLEKAVKDGAFRPELLYRLNVITIWLPPLRERRDDIPLLARHFLEKSCQRLGKEVNGFTHEAMDALIRA
DWPGNVRELENVIERAVILTESKRIELGDLPRQFRNMAAGASGWAFTRGMSFKEAVAAYESRLILQALEESQGVQARAAE
ILGLKRSTLNEMIKRYNLMGRKNGGTNK

Sequences:

>Translated_748_residues
MREIVKTITGKCRMCYACIRNCPVKAIKVVDGQARVVPELCIACGHCVQVCAQGAKLVEREIDKVEEFLAAGRVIACLAP
SFVAEFHPAWPGQVVAALRKLGFDEVYEVAYGAHLVTLEYQKYLQEAGDRQGLISTPCPAIVNLVTKYYPRLLPQLVPVV
SPMIALGRYLKARKGPDVRLVFIGPCVAKKGEAREEEVAGAIDAVLTFLELKEMLVAREIDINLCGNSDFDNDPAYLGRL
YPVGGGLLRSAGIDADILTNQVLVVEGREDCLDFLKAVNEGKMVPQMADMLFCKGCINGPMQENDFSPYRRRKIVAEFTR
QGLQNTRPQPLDLTGINLRREFHDQSVFFPRPSEADIRAILAELGKYTPEDELNCGACGYPSCREKAVAVYHGLAENRMC
LPYFIAQLEKSNFHLRQELKAFQGKFGQLVGNSAAMQEVYRLIEKVAKTDATVLIRGESGTGKELVARAIHYHSRRSEAP
FVSINCAALPETLLESELFGHARGAFTGAVTAKKGLFEEANEGTIFLDEIGDISLGLQSKLLRVLQEGEFLRVGETRPTR
VNVRVLAATNRDLEKAVKDGAFRPELLYRLNVITIWLPPLRERRDDIPLLARHFLEKSCQRLGKEVNGFTHEAMDALIRA
DWPGNVRELENVIERAVILTESKRIELGDLPRQFRNMAAGASGWAFTRGMSFKEAVAAYESRLILQALEESQGVQARAAE
ILGLKRSTLNEMIKRYNLMGRKNGGTNK
>Mature_748_residues
MREIVKTITGKCRMCYACIRNCPVKAIKVVDGQARVVPELCIACGHCVQVCAQGAKLVEREIDKVEEFLAAGRVIACLAP
SFVAEFHPAWPGQVVAALRKLGFDEVYEVAYGAHLVTLEYQKYLQEAGDRQGLISTPCPAIVNLVTKYYPRLLPQLVPVV
SPMIALGRYLKARKGPDVRLVFIGPCVAKKGEAREEEVAGAIDAVLTFLELKEMLVAREIDINLCGNSDFDNDPAYLGRL
YPVGGGLLRSAGIDADILTNQVLVVEGREDCLDFLKAVNEGKMVPQMADMLFCKGCINGPMQENDFSPYRRRKIVAEFTR
QGLQNTRPQPLDLTGINLRREFHDQSVFFPRPSEADIRAILAELGKYTPEDELNCGACGYPSCREKAVAVYHGLAENRMC
LPYFIAQLEKSNFHLRQELKAFQGKFGQLVGNSAAMQEVYRLIEKVAKTDATVLIRGESGTGKELVARAIHYHSRRSEAP
FVSINCAALPETLLESELFGHARGAFTGAVTAKKGLFEEANEGTIFLDEIGDISLGLQSKLLRVLQEGEFLRVGETRPTR
VNVRVLAATNRDLEKAVKDGAFRPELLYRLNVITIWLPPLRERRDDIPLLARHFLEKSCQRLGKEVNGFTHEAMDALIRA
DWPGNVRELENVIERAVILTESKRIELGDLPRQFRNMAAGASGWAFTRGMSFKEAVAAYESRLILQALEESQGVQARAAE
ILGLKRSTLNEMIKRYNLMGRKNGGTNK

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=336, Percent_Identity=49.1071428571429, Blast_Score=319, Evalue=5e-88,
Organism=Escherichia coli, GI87082117, Length=392, Percent_Identity=44.3877551020408, Blast_Score=295, Evalue=8e-81,
Organism=Escherichia coli, GI1790437, Length=433, Percent_Identity=43.64896073903, Blast_Score=295, Evalue=1e-80,
Organism=Escherichia coli, GI1790299, Length=381, Percent_Identity=41.7322834645669, Blast_Score=288, Evalue=1e-78,
Organism=Escherichia coli, GI1789087, Length=354, Percent_Identity=47.1751412429379, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1788905, Length=303, Percent_Identity=46.8646864686469, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI87082152, Length=349, Percent_Identity=44.6991404011461, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=42.8571428571429, Blast_Score=249, Evalue=6e-67,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=41.8238993710692, Blast_Score=232, Evalue=6e-62,
Organism=Escherichia coli, GI1786524, Length=324, Percent_Identity=41.0493827160494, Blast_Score=215, Evalue=1e-56,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=38.0503144654088, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1789828, Length=235, Percent_Identity=37.8723404255319, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081858, Length=331, Percent_Identity=29.3051359516616, Blast_Score=139, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 83173; Mature: 83173

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00198 4FE4S_FERREDOXIN ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVKTITGKCRMCYACIRNCPVKAIKVVDGQARVVPELCIACGHCVQVCAQGAKLVER
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIDKVEEFLAAGRVIACLAPSFVAEFHPAWPGQVVAALRKLGFDEVYEVAYGAHLVTLEY
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEHHH
QKYLQEAGDRQGLISTPCPAIVNLVTKYYPRLLPQLVPVVSPMIALGRYLKARKGPDVRL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VFIGPCVAKKGEAREEEVAGAIDAVLTFLELKEMLVAREIDINLCGNSDFDNDPAYLGRL
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHCEE
YPVGGGLLRSAGIDADILTNQVLVVEGREDCLDFLKAVNEGKMVPQMADMLFCKGCINGP
ECCCCHHHHHCCCCHHHHCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
MQENDFSPYRRRKIVAEFTRQGLQNTRPQPLDLTGINLRREFHDQSVFFPRPSEADIRAI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHH
LAELGKYTPEDELNCGACGYPSCREKAVAVYHGLAENRMCLPYFIAQLEKSNFHLRQELK
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHH
AFQGKFGQLVGNSAAMQEVYRLIEKVAKTDATVLIRGESGTGKELVARAIHYHSRRSEAP
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCC
FVSINCAALPETLLESELFGHARGAFTGAVTAKKGLFEEANEGTIFLDEIGDISLGLQSK
EEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LLRVLQEGEFLRVGETRPTRVNVRVLAATNRDLEKAVKDGAFRPELLYRLNVITIWLPPL
HHHHHHCCCEEEECCCCCCEEEEEEEEECCHHHHHHHHCCCCCHHHHHEEEEEEEECCCH
RERRDDIPLLARHFLEKSCQRLGKEVNGFTHEAMDALIRADWPGNVRELENVIERAVILT
HCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
ESKRIELGDLPRQFRNMAAGASGWAFTRGMSFKEAVAAYESRLILQALEESQGVQARAAE
CCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILGLKRSTLNEMIKRYNLMGRKNGGTNK
HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MREIVKTITGKCRMCYACIRNCPVKAIKVVDGQARVVPELCIACGHCVQVCAQGAKLVER
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIDKVEEFLAAGRVIACLAPSFVAEFHPAWPGQVVAALRKLGFDEVYEVAYGAHLVTLEY
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEHHH
QKYLQEAGDRQGLISTPCPAIVNLVTKYYPRLLPQLVPVVSPMIALGRYLKARKGPDVRL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VFIGPCVAKKGEAREEEVAGAIDAVLTFLELKEMLVAREIDINLCGNSDFDNDPAYLGRL
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHCEE
YPVGGGLLRSAGIDADILTNQVLVVEGREDCLDFLKAVNEGKMVPQMADMLFCKGCINGP
ECCCCHHHHHCCCCHHHHCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
MQENDFSPYRRRKIVAEFTRQGLQNTRPQPLDLTGINLRREFHDQSVFFPRPSEADIRAI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHH
LAELGKYTPEDELNCGACGYPSCREKAVAVYHGLAENRMCLPYFIAQLEKSNFHLRQELK
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHH
AFQGKFGQLVGNSAAMQEVYRLIEKVAKTDATVLIRGESGTGKELVARAIHYHSRRSEAP
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCC
FVSINCAALPETLLESELFGHARGAFTGAVTAKKGLFEEANEGTIFLDEIGDISLGLQSK
EEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LLRVLQEGEFLRVGETRPTRVNVRVLAATNRDLEKAVKDGAFRPELLYRLNVITIWLPPL
HHHHHHCCCEEEECCCCCCEEEEEEEEECCHHHHHHHHCCCCCHHHHHEEEEEEEECCCH
RERRDDIPLLARHFLEKSCQRLGKEVNGFTHEAMDALIRADWPGNVRELENVIERAVILT
HCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
ESKRIELGDLPRQFRNMAAGASGWAFTRGMSFKEAVAAYESRLILQALEESQGVQARAAE
CCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILGLKRSTLNEMIKRYNLMGRKNGGTNK
HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]