Click here to switch to the map view.

The map label for this gene is ruvB

Identifier: 83590536

GI number: 83590536

Start: 1737592

End: 1738602

Strand: Reverse

Name: ruvB

Synonym: Moth_1700

Alternate gene names: 83590536

Gene position: 1738602-1737592 (Counterclockwise)

Preceding gene: 83590537

Following gene: 83590535

Centisome position: 66.14

GC content: 62.22

Gene sequence:

>1011_bases
TTGGCAACGGAGAGGTTAGTAGCCGGAAACCTGCATAATGAAGACCAGGAACTTGAATTGAGCCTGCGACCGCGCTGCCT
GGCAGAGTACATCGGCCAGGAACATGTCAAGGAGACCCTGGGCATCTTTATCCAGGCGGCCCGTGAACGGGGTGAAGCCT
TGGACCACGTCCTTCTCTACGGGCCCCCGGGGCTTGGTAAGACCACCCTGGCCGGGATTATCGCCAATGAGCTAGGGGTC
CAGCTGCGGGTCACCTCGGGACCGGCCCTGGAACGGGCCGGGGACCTGGCAGCCATCTTGACCAACCTGCAGCCCCGGGA
CGTCCTCTTTATCGATGAAATCCACCGCCTGCCCCGCCAGGTGGAGGAGATCCTTTACCCGGCCATGGAAGACTTCGTCT
TAGATATTATCCTGGGTAAGGGTCCCGGCGCCCGTTCCATTCGCCTGGACCTGCCCCCCTTTACCCTGGTGGGAGCGACT
ACCAGGGCGGGGTTGCTATCTTCCCCTTTAAGGGATCGCTTCGGCATCAATTCCCGCCTGGAGTTTTACCAGGTGGCCGA
GCTGGAAGAGATTATCAGGCGGGCGGCCACCATCCTCCAGGTTGCCATCGAGCCGGAAGGAGCCAGGGAGATCGCCCGGC
GCGCCCGGGGGACGCCCAGGGTAGCCAACCGCTTGTTGAAGCGGGTCAGGGATTACGCCGAGATCCGGGCCGGAGGAGTC
ATTACCAGGGAGGTGGCCCGGGAGGCCCTGGAACTCCTGCAGGTTGATGCCGCCGGCCTGGATAGTTCAGACCGGCGCCT
TCTGCTCACCCTTATCCGCAAGTTTAACGGGGGACCCGTCGGTCTCGAGACCCTGGCCGCAGCCATCAGCGAGGAACCGG
ACACCATTGAGGACGTCTACGAACCCTTTTTACTCCAGATGGGCTACCTCCAGCGTACTCCCAGGGGCCGGGTGGCTACC
CCCGGAGCCTATGCACACCTGGGTATTAAGCCGGAAGACCGGTTGTTTTGA

Upstream 100 bases:

>100_bases
GATCCTGGCCAGGGTACGGCAGGAACTGGGGAATGCTGCCCCTACGACAGCCGTCCTCCAGGCGGTACTAAAAACCTTTG
GCCGGGGGGGAGGGGATTAA

Downstream 100 bases:

>100_bases
TAGAACCCTTCATTGGGAACTAACGCCCTGTACAAGCCCGGAAAGTGAACTGTATAGAGGGTAGACCTCTATTTTTTGGA
GGGGGAAAGTTTCGTGGGCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MATERLVAGNLHNEDQELELSLRPRCLAEYIGQEHVKETLGIFIQAARERGEALDHVLLYGPPGLGKTTLAGIIANELGV
QLRVTSGPALERAGDLAAILTNLQPRDVLFIDEIHRLPRQVEEILYPAMEDFVLDIILGKGPGARSIRLDLPPFTLVGAT
TRAGLLSSPLRDRFGINSRLEFYQVAELEEIIRRAATILQVAIEPEGAREIARRARGTPRVANRLLKRVRDYAEIRAGGV
ITREVAREALELLQVDAAGLDSSDRRLLLTLIRKFNGGPVGLETLAAAISEEPDTIEDVYEPFLLQMGYLQRTPRGRVAT
PGAYAHLGIKPEDRLF

Sequences:

>Translated_336_residues
MATERLVAGNLHNEDQELELSLRPRCLAEYIGQEHVKETLGIFIQAARERGEALDHVLLYGPPGLGKTTLAGIIANELGV
QLRVTSGPALERAGDLAAILTNLQPRDVLFIDEIHRLPRQVEEILYPAMEDFVLDIILGKGPGARSIRLDLPPFTLVGAT
TRAGLLSSPLRDRFGINSRLEFYQVAELEEIIRRAATILQVAIEPEGAREIARRARGTPRVANRLLKRVRDYAEIRAGGV
ITREVAREALELLQVDAAGLDSSDRRLLLTLIRKFNGGPVGLETLAAAISEEPDTIEDVYEPFLLQMGYLQRTPRGRVAT
PGAYAHLGIKPEDRLF
>Mature_335_residues
ATERLVAGNLHNEDQELELSLRPRCLAEYIGQEHVKETLGIFIQAARERGEALDHVLLYGPPGLGKTTLAGIIANELGVQ
LRVTSGPALERAGDLAAILTNLQPRDVLFIDEIHRLPRQVEEILYPAMEDFVLDIILGKGPGARSIRLDLPPFTLVGATT
RAGLLSSPLRDRFGINSRLEFYQVAELEEIIRRAATILQVAIEPEGAREIARRARGTPRVANRLLKRVRDYAEIRAGGVI
TREVAREALELLQVDAAGLDSSDRRLLLTLIRKFNGGPVGLETLAAAISEEPDTIEDVYEPFLLQMGYLQRTPRGRVATP
GAYAHLGIKPEDRLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=328, Percent_Identity=62.1951219512195, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1787119, Length=134, Percent_Identity=37.3134328358209, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_MOOTA (Q2RHT7)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430545.1
- ProteinModelPortal:   Q2RHT7
- SMR:   Q2RHT7
- STRING:   Q2RHT7
- GeneID:   3833300
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1700
- NMPDR:   fig|264732.9.peg.1699
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q2RHT7
- ProtClustDB:   PRK00080
- BioCyc:   MTHE264732:MOTH_1700-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37109; Mature: 36978

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATERLVAGNLHNEDQELELSLRPRCLAEYIGQEHVKETLGIFIQAARERGEALDHVLLY
CCCCCCEECCCCCCCCCEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEE
GPPGLGKTTLAGIIANELGVQLRVTSGPALERAGDLAAILTNLQPRDVLFIDEIHRLPRQ
CCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VEEILYPAMEDFVLDIILGKGPGARSIRLDLPPFTLVGATTRAGLLSSPLRDRFGINSRL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHHHCCHHHHCCCCCCH
EFYQVAELEEIIRRAATILQVAIEPEGAREIARRARGTPRVANRLLKRVRDYAEIRAGGV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCH
ITREVAREALELLQVDAAGLDSSDRRLLLTLIRKFNGGPVGLETLAAAISEEPDTIEDVY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHH
EPFLLQMGYLQRTPRGRVATPGAYAHLGIKPEDRLF
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHCCC
>Mature Secondary Structure 
ATERLVAGNLHNEDQELELSLRPRCLAEYIGQEHVKETLGIFIQAARERGEALDHVLLY
CCCCCEECCCCCCCCCEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEE
GPPGLGKTTLAGIIANELGVQLRVTSGPALERAGDLAAILTNLQPRDVLFIDEIHRLPRQ
CCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VEEILYPAMEDFVLDIILGKGPGARSIRLDLPPFTLVGATTRAGLLSSPLRDRFGINSRL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHHHCCHHHHCCCCCCH
EFYQVAELEEIIRRAATILQVAIEPEGAREIARRARGTPRVANRLLKRVRDYAEIRAGGV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCH
ITREVAREALELLQVDAAGLDSSDRRLLLTLIRKFNGGPVGLETLAAAISEEPDTIEDVY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHH
EPFLLQMGYLQRTPRGRVATPGAYAHLGIKPEDRLF
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA