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The map label for this gene is cymR [H]

Identifier: 83590489

GI number: 83590489

Start: 1687783

End: 1688235

Strand: Reverse

Name: cymR [H]

Synonym: Moth_1653

Alternate gene names: 83590489

Gene position: 1688235-1687783 (Counterclockwise)

Preceding gene: 83590490

Following gene: 83590488

Centisome position: 64.22

GC content: 56.95

Gene sequence:

>453_bases
GTGAAACTCTCGACCCGGGGTGAGTATGGCCTCCGGGCCATGTTCGACCTGGCCCAGCATTATGGCGAAGGCCCCATCCC
CATTAAAAGCGTTGCCGAGAGGCAGGACATATCTGAACACTACCTGGAGCAATTGATCGCCGTCTTGCGTAAAGCTGGCC
TGGTCAAGAGCATCCGCGGCGCCCAGGGCGGATATGTCCTCAGCCGGGAACCCGAGGAGATTACGGTAGGGGATATTATC
CGGGTTTTGGAAGGCCCTATTGCTCCGGTGGAATGCCTGAATACCGCCGAAGGCGAGAGCTGCGAGCGGGCCGAGACTTG
CGTCACCAGGGGCATCTGGGAGAAGGTGCGGGATAGCATTAGCGACGTCCTGGATAGCTTTACCCTGGCGGATATGGTCG
CCAAGGCCAATCAAATGCGCCAGGACAGCAAATACTATATGTATTATATCTAG

Upstream 100 bases:

>100_bases
TAAAAGCTGAGTAAAAAAGTCGAGTTTAGCGTTGACAATATCCGAGTCAATTGCTAAGATATTATTGCCTAGGAAACTAG
TAGGGATTGGAGGTGGTGGG

Downstream 100 bases:

>100_bases
AAAAGGGTGGACGAGATGCGCAGGGTTTACCTTGATCATAGCGCCACAACTCCGGTAAGGCCCGAAGTCCTGGAGGCCAT
GTTACCCTTTTTGAAGGATG

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKLSTRGEYGLRAMFDLAQHYGEGPIPIKSVAERQDISEHYLEQLIAVLRKAGLVKSIRGAQGGYVLSREPEEITVGDII
RVLEGPIAPVECLNTAEGESCERAETCVTRGIWEKVRDSISDVLDSFTLADMVAKANQMRQDSKYYMYYI

Sequences:

>Translated_150_residues
MKLSTRGEYGLRAMFDLAQHYGEGPIPIKSVAERQDISEHYLEQLIAVLRKAGLVKSIRGAQGGYVLSREPEEITVGDII
RVLEGPIAPVECLNTAEGESCERAETCVTRGIWEKVRDSISDVLDSFTLADMVAKANQMRQDSKYYMYYI
>Mature_150_residues
MKLSTRGEYGLRAMFDLAQHYGEGPIPIKSVAERQDISEHYLEQLIAVLRKAGLVKSIRGAQGGYVLSREPEEITVGDII
RVLEGPIAPVECLNTAEGESCERAETCVTRGIWEKVRDSISDVLDSFTLADMVAKANQMRQDSKYYMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=133, Percent_Identity=36.0902255639098, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790621, Length=133, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16820; Mature: 16820

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTRGEYGLRAMFDLAQHYGEGPIPIKSVAERQDISEHYLEQLIAVLRKAGLVKSIRG
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQGGYVLSREPEEITVGDIIRVLEGPIAPVECLNTAEGESCERAETCVTRGIWEKVRDSI
CCCCEEECCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SDVLDSFTLADMVAKANQMRQDSKYYMYYI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKLSTRGEYGLRAMFDLAQHYGEGPIPIKSVAERQDISEHYLEQLIAVLRKAGLVKSIRG
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQGGYVLSREPEEITVGDIIRVLEGPIAPVECLNTAEGESCERAETCVTRGIWEKVRDSI
CCCCEEECCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SDVLDSFTLADMVAKANQMRQDSKYYMYYI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]