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The map label for this gene is hmeD [H]

Identifier: 83590469

GI number: 83590469

Start: 1668041

End: 1669420

Strand: Reverse

Name: hmeD [H]

Synonym: Moth_1633

Alternate gene names: 83590469

Gene position: 1669420-1668041 (Counterclockwise)

Preceding gene: 83590470

Following gene: 83590468

Centisome position: 63.51

GC content: 55.22

Gene sequence:

>1380_bases
ATGCGTAAAGTCTTTGACGATTACCGGGTGCTCTCAGATGAGACCCTGAAACCAGACGCGCCACGGGTGGAAAAATTCCT
CCAGGCCATGGGGAAATCCCTCCGGCAGCGGGATAACTGGACCTTTTGGCTCCCCTATACCCTATCCCTGGATACCTGCA
TGAAGTGCGGTACCTGCGCCGAGGTCTGCCCGGTCTACCTGGCCAGCGGCCGCAAAGACATCTACCATCCGGTCTACCGT
TCCGACATGCTGCGTAAGGTTTATAAACGGTATTTTACCCTGGCAGGAAGGTTTTTTCCGGGCCTGGTGGGAGCGGAAGA
CCTGACGGAAGATAAACTCAATGCCATGGCCGAGAATATTTACCGGTGTACCATTTGCCGCCGCTGTGCCTATGTTTGCC
CGGTAGCCATTGATAACGGCTTGATTGCCCGGGAAGCACGGAAAATCTTCGACGCCATCGATATCGCCCCCGACGAGCTG
AAGAAAAACGGCACCCGGAAACAGGTCCGGCTGGGTAACGCCACCGGTATGCCGGCCAACGCCTTTTTTGACATGATTGA
GTTCCTGGAGGAAGAGATTGAGGATACACGGGGATATAAAATTAAAATACCGGTTGATAAGCAGGGCGCCGAGTACCTCC
TCATGCATAACGCCGGCGACTACCTGGCCTTTGCCGAGACGGTAATGGGCGCCGCCGAAGTCATGAACGCCGCCGGTGTC
GACTGGACCCTCAATTCCCCGGAAACGGGCCTCAACGATGCCGTCAATTACGGCGTCTTTTACAGCGATACCGAGTTCGC
CAGTGTTGCCAGGGCCCATATCGAAACTGCCAAAAAGTTAGGGATTAAGACTTTCGTCGTAGGCGAGTGCGGTCATGCCT
TCGAGGCGCTGAAGTACCTGATCTTGCGCCTCGTCCCCCCGGAAGAAAGGCCTTTTGAGGTCAAGAGCATCCTGGAACTG
GAGGATCAATGGATCCGGGAAGGGCGGATTAAGGTCGACCCCCAGAAGAACCCTGAACCTGTGACCTACCATGATTCCTG
CAAGCTGGGCCGCCTGGGAGGGCTCTATGAGGAGCCGCGGCGCATCCTCAAAGCCTGCTGCACTGATTTTCGCGAAATGA
CGCCCAACCGGGAAATGAGTATTTGCTGCGGCGGTGGCAGCGGTTTTGCCATTATGGATAAGGGCGACTTCCTTAAATTC
CGCATGGAAACCTACGGTAAGCTCAAAGCCGAGCAGCTAAAAGCCACCGGCGCCAGCATTGTAGCCCTGGCCTGCTCCAA
TTGTAAGGGCCAGTTCCGGGAGATTATCAACTACTATAAGCTGCCGGTACGTTTCATGGGTGTCAGTGAGCTGGTGGCTA
ATGCCCTGGTGTACAATTAA

Upstream 100 bases:

>100_bases
TATTTGAGCTTTTCTTGGTTTACCTGCCCTTTACCCGAATGGCGCATTTCGCCGTCAAGTATTTTACCTACCACAAGGTC
AAGTGGGGTGAAATGGAATA

Downstream 100 bases:

>100_bases
TTGTTAATCATGGTGTTTTTAGCCTGTAGCCTTTAATCGAGGGTACAGGTATAATAAAATCTGGCAGGAGGTGTTTGACA
TGCCGACGGTAAATCTCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Hme subunit D [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRKVFDDYRVLSDETLKPDAPRVEKFLQAMGKSLRQRDNWTFWLPYTLSLDTCMKCGTCAEVCPVYLASGRKDIYHPVYR
SDMLRKVYKRYFTLAGRFFPGLVGAEDLTEDKLNAMAENIYRCTICRRCAYVCPVAIDNGLIAREARKIFDAIDIAPDEL
KKNGTRKQVRLGNATGMPANAFFDMIEFLEEEIEDTRGYKIKIPVDKQGAEYLLMHNAGDYLAFAETVMGAAEVMNAAGV
DWTLNSPETGLNDAVNYGVFYSDTEFASVARAHIETAKKLGIKTFVVGECGHAFEALKYLILRLVPPEERPFEVKSILEL
EDQWIREGRIKVDPQKNPEPVTYHDSCKLGRLGGLYEEPRRILKACCTDFREMTPNREMSICCGGGSGFAIMDKGDFLKF
RMETYGKLKAEQLKATGASIVALACSNCKGQFREIINYYKLPVRFMGVSELVANALVYN

Sequences:

>Translated_459_residues
MRKVFDDYRVLSDETLKPDAPRVEKFLQAMGKSLRQRDNWTFWLPYTLSLDTCMKCGTCAEVCPVYLASGRKDIYHPVYR
SDMLRKVYKRYFTLAGRFFPGLVGAEDLTEDKLNAMAENIYRCTICRRCAYVCPVAIDNGLIAREARKIFDAIDIAPDEL
KKNGTRKQVRLGNATGMPANAFFDMIEFLEEEIEDTRGYKIKIPVDKQGAEYLLMHNAGDYLAFAETVMGAAEVMNAAGV
DWTLNSPETGLNDAVNYGVFYSDTEFASVARAHIETAKKLGIKTFVVGECGHAFEALKYLILRLVPPEERPFEVKSILEL
EDQWIREGRIKVDPQKNPEPVTYHDSCKLGRLGGLYEEPRRILKACCTDFREMTPNREMSICCGGGSGFAIMDKGDFLKF
RMETYGKLKAEQLKATGASIVALACSNCKGQFREIINYYKLPVRFMGVSELVANALVYN
>Mature_459_residues
MRKVFDDYRVLSDETLKPDAPRVEKFLQAMGKSLRQRDNWTFWLPYTLSLDTCMKCGTCAEVCPVYLASGRKDIYHPVYR
SDMLRKVYKRYFTLAGRFFPGLVGAEDLTEDKLNAMAENIYRCTICRRCAYVCPVAIDNGLIAREARKIFDAIDIAPDEL
KKNGTRKQVRLGNATGMPANAFFDMIEFLEEEIEDTRGYKIKIPVDKQGAEYLLMHNAGDYLAFAETVMGAAEVMNAAGV
DWTLNSPETGLNDAVNYGVFYSDTEFASVARAHIETAKKLGIKTFVVGECGHAFEALKYLILRLVPPEERPFEVKSILEL
EDQWIREGRIKVDPQKNPEPVTYHDSCKLGRLGGLYEEPRRILKACCTDFREMTPNREMSICCGGGSGFAIMDKGDFLKF
RMETYGKLKAEQLKATGASIVALACSNCKGQFREIINYYKLPVRFMGVSELVANALVYN

Specific function: Has menaquinol-oxidizing activity. HmeC and hmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51896; Mature: 51896

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVFDDYRVLSDETLKPDAPRVEKFLQAMGKSLRQRDNWTFWLPYTLSLDTCMKCGTCA
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHCCCCHH
EVCPVYLASGRKDIYHPVYRSDMLRKVYKRYFTLAGRFFPGLVGAEDLTEDKLNAMAENI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YRCTICRRCAYVCPVAIDNGLIAREARKIFDAIDIAPDELKKNGTRKQVRLGNATGMPAN
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHEEEECCCCCCCHH
AFFDMIEFLEEEIEDTRGYKIKIPVDKQGAEYLLMHNAGDYLAFAETVMGAAEVMNAAGV
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCC
DWTLNSPETGLNDAVNYGVFYSDTEFASVARAHIETAKKLGIKTFVVGECGHAFEALKYL
CEECCCCCCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHH
ILRLVPPEERPFEVKSILELEDQWIREGRIKVDPQKNPEPVTYHDSCKLGRLGGLYEEPR
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEECCCCCCCCCCCCHHHHH
RILKACCTDFREMTPNREMSICCGGGSGFAIMDKGDFLKFRMETYGKLKAEQLKATGASI
HHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCHHEEEHHHHCCHHHHHHHHCCCCE
VALACSNCKGQFREIINYYKLPVRFMGVSELVANALVYN
EEHHHHCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRKVFDDYRVLSDETLKPDAPRVEKFLQAMGKSLRQRDNWTFWLPYTLSLDTCMKCGTCA
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHCCCCHH
EVCPVYLASGRKDIYHPVYRSDMLRKVYKRYFTLAGRFFPGLVGAEDLTEDKLNAMAENI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YRCTICRRCAYVCPVAIDNGLIAREARKIFDAIDIAPDELKKNGTRKQVRLGNATGMPAN
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHEEEECCCCCCCHH
AFFDMIEFLEEEIEDTRGYKIKIPVDKQGAEYLLMHNAGDYLAFAETVMGAAEVMNAAGV
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCC
DWTLNSPETGLNDAVNYGVFYSDTEFASVARAHIETAKKLGIKTFVVGECGHAFEALKYL
CEECCCCCCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHH
ILRLVPPEERPFEVKSILELEDQWIREGRIKVDPQKNPEPVTYHDSCKLGRLGGLYEEPR
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEECCCCCCCCCCCCHHHHH
RILKACCTDFREMTPNREMSICCGGGSGFAIMDKGDFLKFRMETYGKLKAEQLKATGASI
HHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCHHEEEHHHHCCHHHHHHHHCCCCE
VALACSNCKGQFREIINYYKLPVRFMGVSELVANALVYN
EEHHHHCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]