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The map label for this gene is aroA [H]

Identifier: 83590179

GI number: 83590179

Start: 1378015

End: 1379322

Strand: Reverse

Name: aroA [H]

Synonym: Moth_1332

Alternate gene names: 83590179

Gene position: 1379322-1378015 (Counterclockwise)

Preceding gene: 83590180

Following gene: 83590178

Centisome position: 52.47

GC content: 62.54

Gene sequence:

>1308_bases
ATGCGGCTTATTATTCAACCCCCGCCATCCCTGGAAGGGAATATCCAGCCGCCGGGGGATAAATCCATATCCCACCGGGC
GGCCATCATCGGCGCCCTGGCCGAAGGTACAACTGTCATCGACGGCTTCCTGGCGGGGGCTGACTGCCTCAGTACCTTGA
ATTGCCTGCGCGCCCTGGGGGTAGACATTGCAGGACCGGACGGGGGCCGGGTAGTGGTGCGGGGCGGGGGGTTAGATTCC
CTTAAGGAGCCGGAGACGGTTCTCGATGCCGGCAATTCCGGGACGACCATGCGCCTTCTCCTGGGTGTCCTGGCCGGGCA
GCCCTTTTACAGTGTAATTAATGGCGATGAATCCTTACGCCGACGACCCATGGGCCGGGTTACGGGACCACTGAGGTCGA
TGGGGGCCGCAATCTGGGGCCGGCAGAATGGGGAACTGGCACCCTTAAGTGTCCGGGGCGGCAAGTTAGAACCCCTGGCG
TACACCTTGCCTGTAGCCAGCGCCCAGGTTAAATCGGCCCTCCTCCTGGCCGGCCTTTTCACCTCCGGGGAAACCATCGT
TACCGAGCCCTGCCGCTCACGGGACCACAGCGAAAGGATGCTCCGGGCCGCCGGGGCCGACCTCCGGGTTGAGGGCTTGC
GGGTGAGGATCAGGGGCCGGAAACCCCTTAAACCTCTGACCATTAACGTGCCCGGTGATATCTCGGCAGCCGCCTTTTTC
CTGGTGGCCGGTTGCCTGCACCCCCGGGCCGCCCTTACACTGGAAAAAGTAAACTTAAATCCCACCAGGACGGGCATTAT
CGACGTCCTGACGGCAATGGGGGCGCCACTTGAAATAATCCCCGGGGAAGAAACAGCTGGGGAACCTGCCGGGTCAATCC
GGGTGACCTCCGGCAGACTTCACGGCCTGGAAGTGGGCGGGGCCATGATCCCCCGGTTAATCGATGAAATACCGGTCCTG
GCGGTGGCCGCCGCCCTGGCCGAAGGGGAAACCCTTATCCGTGGCGCCGCCGAGCTAAAAGTGAAGGAAAGCGACCGCAT
TGCCATGGTGGCCGGGGAACTGGCCCGCATGGGAGCGGAGATTTATGCCCGGCCCGATGGTTTCCGGATCAAGGGGGTAC
GCCGCCTTCGCGGGGCGGTGGTTGACAGTCACGGGGATCATCGCCTGGCCATGGCCCTGGCGATGGCGGGCCTGGTGGCT
GAAGGTACAACAGAGGTCAGGGGAGCGGAATGTATCGCTATATCATATCCCGGCTTTACTGCCGATCTGGCCAGGCTGGG
GGTTATGGTGAAGGAAGAAGATGATTGA

Upstream 100 bases:

>100_bases
CAAAATTCCGGGATTAATGTACGACTACTGGAAAATGCTTGACACCGCGGGTTATTCCTGGTAGTTTGAGAAAAGAAACC
TAGCTTTTGCGGAGGAAAAG

Downstream 100 bases:

>100_bases
GAAAATGCAGGGTAATATTGCCATCGACGGCCCGGCAGGAGCCGGTAAGAGTACCGTGGCCCGACTCCTGGCGGCCAGAT
TGGGTTATCTATATATCGAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MRLIIQPPPSLEGNIQPPGDKSISHRAAIIGALAEGTTVIDGFLAGADCLSTLNCLRALGVDIAGPDGGRVVVRGGGLDS
LKEPETVLDAGNSGTTMRLLLGVLAGQPFYSVINGDESLRRRPMGRVTGPLRSMGAAIWGRQNGELAPLSVRGGKLEPLA
YTLPVASAQVKSALLLAGLFTSGETIVTEPCRSRDHSERMLRAAGADLRVEGLRVRIRGRKPLKPLTINVPGDISAAAFF
LVAGCLHPRAALTLEKVNLNPTRTGIIDVLTAMGAPLEIIPGEETAGEPAGSIRVTSGRLHGLEVGGAMIPRLIDEIPVL
AVAAALAEGETLIRGAAELKVKESDRIAMVAGELARMGAEIYARPDGFRIKGVRRLRGAVVDSHGDHRLAMALAMAGLVA
EGTTEVRGAECIAISYPGFTADLARLGVMVKEEDD

Sequences:

>Translated_435_residues
MRLIIQPPPSLEGNIQPPGDKSISHRAAIIGALAEGTTVIDGFLAGADCLSTLNCLRALGVDIAGPDGGRVVVRGGGLDS
LKEPETVLDAGNSGTTMRLLLGVLAGQPFYSVINGDESLRRRPMGRVTGPLRSMGAAIWGRQNGELAPLSVRGGKLEPLA
YTLPVASAQVKSALLLAGLFTSGETIVTEPCRSRDHSERMLRAAGADLRVEGLRVRIRGRKPLKPLTINVPGDISAAAFF
LVAGCLHPRAALTLEKVNLNPTRTGIIDVLTAMGAPLEIIPGEETAGEPAGSIRVTSGRLHGLEVGGAMIPRLIDEIPVL
AVAAALAEGETLIRGAAELKVKESDRIAMVAGELARMGAEIYARPDGFRIKGVRRLRGAVVDSHGDHRLAMALAMAGLVA
EGTTEVRGAECIAISYPGFTADLARLGVMVKEEDD
>Mature_435_residues
MRLIIQPPPSLEGNIQPPGDKSISHRAAIIGALAEGTTVIDGFLAGADCLSTLNCLRALGVDIAGPDGGRVVVRGGGLDS
LKEPETVLDAGNSGTTMRLLLGVLAGQPFYSVINGDESLRRRPMGRVTGPLRSMGAAIWGRQNGELAPLSVRGGKLEPLA
YTLPVASAQVKSALLLAGLFTSGETIVTEPCRSRDHSERMLRAAGADLRVEGLRVRIRGRKPLKPLTINVPGDISAAAFF
LVAGCLHPRAALTLEKVNLNPTRTGIIDVLTAMGAPLEIIPGEETAGEPAGSIRVTSGRLHGLEVGGAMIPRLIDEIPVL
AVAAALAEGETLIRGAAELKVKESDRIAMVAGELARMGAEIYARPDGFRIKGVRRLRGAVVDSHGDHRLAMALAMAGLVA
EGTTEVRGAECIAISYPGFTADLARLGVMVKEEDD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=29.3577981651376, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=463, Percent_Identity=26.9978401727862, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45467; Mature: 45467

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00626 RCC1_2 ; PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIIQPPPSLEGNIQPPGDKSISHRAAIIGALAEGTTVIDGFLAGADCLSTLNCLRALG
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
VDIAGPDGGRVVVRGGGLDSLKEPETVLDAGNSGTTMRLLLGVLAGQPFYSVINGDESLR
CEEECCCCCEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCEEHHCCCHHHH
RRPMGRVTGPLRSMGAAIWGRQNGELAPLSVRGGKLEPLAYTLPVASAQVKSALLLAGLF
HCCCCHHCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHH
TSGETIVTEPCRSRDHSERMLRAAGADLRVEGLRVRIRGRKPLKPLTINVPGDISAAAFF
CCCCEEEECCCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEECCCCHHHHHHH
LVAGCLHPRAALTLEKVNLNPTRTGIIDVLTAMGAPLEIIPGEETAGEPAGSIRVTSGRL
HHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCE
HGLEVGGAMIPRLIDEIPVLAVAAALAEGETLIRGAAELKVKESDRIAMVAGELARMGAE
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHEEEECCCCEEEHHHHHHHCCCC
IYARPDGFRIKGVRRLRGAVVDSHGDHRLAMALAMAGLVAEGTTEVRGAECIAISYPGFT
EEECCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCH
ADLARLGVMVKEEDD
HHHHHHCEEEEECCC
>Mature Secondary Structure
MRLIIQPPPSLEGNIQPPGDKSISHRAAIIGALAEGTTVIDGFLAGADCLSTLNCLRALG
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
VDIAGPDGGRVVVRGGGLDSLKEPETVLDAGNSGTTMRLLLGVLAGQPFYSVINGDESLR
CEEECCCCCEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCEEHHCCCHHHH
RRPMGRVTGPLRSMGAAIWGRQNGELAPLSVRGGKLEPLAYTLPVASAQVKSALLLAGLF
HCCCCHHCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHH
TSGETIVTEPCRSRDHSERMLRAAGADLRVEGLRVRIRGRKPLKPLTINVPGDISAAAFF
CCCCEEEECCCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEECCCCHHHHHHH
LVAGCLHPRAALTLEKVNLNPTRTGIIDVLTAMGAPLEIIPGEETAGEPAGSIRVTSGRL
HHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCE
HGLEVGGAMIPRLIDEIPVLAVAAALAEGETLIRGAAELKVKESDRIAMVAGELARMGAE
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHEEEECCCCEEEHHHHHHHCCCC
IYARPDGFRIKGVRRLRGAVVDSHGDHRLAMALAMAGLVAEGTTEVRGAECIAISYPGFT
EEECCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCH
ADLARLGVMVKEEDD
HHHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA