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The map label for this gene is gpsA

Identifier: 83590167

GI number: 83590167

Start: 1365487

End: 1366494

Strand: Reverse

Name: gpsA

Synonym: Moth_1320

Alternate gene names: 83590167

Gene position: 1366494-1365487 (Counterclockwise)

Preceding gene: 83590168

Following gene: 83590166

Centisome position: 51.98

GC content: 59.52

Gene sequence:

>1008_bases
GTGAAGGAAAGTATAGCCGTTCTTGGCGCCGGCAGCTGGGGGACGGCCCTGGCCGTACTACTGGCCCATAAGGGCTTCAG
GGTCAACCTCTGGGCCCGGCGGCCGGAACTGGCGACGGCTTTAAGGGAAACTGGAGAAAACAAAACCTATCTACCGGGAG
TGAGATTAACTGGGACGATTATTCCCACGGCCGATCTGCCTGCGGCTGTCAAAGGCGCAGGGCTGGTGGTCTTGAGCGTA
CCCTCCCATGCCGTCCGTTCGACGGCCCGGCTTCTCAAACCCTTTTTGCCTAAGGGAACCGTTGTTGTCAATACAGCCAA
GGGCCTGGAGTTGGAGACGAAAAAACGTTTATCCCAGGTTCTGGTTGAAGAAGGCCTGGACCGGGTAGCCGTTCTATCCG
GCCCCAGTCATGCTGAGGAAGTCGGGCGTGGCCTGCCGACTACGGTTGTGGTTGCTGCTGCTGACCGGGAGACGGCCGAA
TATGTCCAGGACGTTTTTATGGACCCGACCTTCCGGGTCTATACCAACCCTGACATTATAGGTGTAGAATTCGGGGGAGC
TTTAAAGAATATCATTGCCCTGGCCACCGGCATGGCCGACGGCCTGGGCCTGGGTGATAATACCCGGGCCGCCCTGATGA
CCAGGGGTATGGCGGAGATTGCCCGCCTGGGTGTCGCCCTGGGGGGCAAAGTCTTGACCTTTGCCGGTTTGAGCGGTATC
GGCGATTTGATTGTAACCTGCACCTCCATGTACAGTCGCAATCGCCGCGCCGGCATCCTCCTGGGCAAGGGTCAATCCCT
GGAAGAGGTCCTGGACGCGGTGGGCATGGTGGTGGAGGGTGTCCGGACCACGGCCGCGGCTCGGGAACTGGCCTGCCAGC
ATGGCATCAAAATGCCCATCACCGAAGAGATCTACCAGGTGCTTTATAAGGGTAAACCCGTGGGCGATTGTGTCGCCGCC
CTGATGGAACGGCCCCGGACCCATGAAGTGGAGTCAGGCGACTGGTAA

Upstream 100 bases:

>100_bases
GTTTACCTTTGTGGCGGCAGCCCTGGTAATCTACCGTCACCGGCCAAACATTAAACGCCTGCTGGCAGGTACCGAACACA
AACTGGGGGAGCGAAGCTAA

Downstream 100 bases:

>100_bases
GGTCATTGCTGGAAACCCGCCCTTCAGGCGGGTCTTTTATTTTTACCCCGATATTCCTGCCTTTCCCGGTTCTTTTCGTG
TGGCTGCCTGAATATATTCT

Product: NAD-dependent glycerol-3-phosphate dehydrogenase-like

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKESIAVLGAGSWGTALAVLLAHKGFRVNLWARRPELATALRETGENKTYLPGVRLTGTIIPTADLPAAVKGAGLVVLSV
PSHAVRSTARLLKPFLPKGTVVVNTAKGLELETKKRLSQVLVEEGLDRVAVLSGPSHAEEVGRGLPTTVVVAAADRETAE
YVQDVFMDPTFRVYTNPDIIGVEFGGALKNIIALATGMADGLGLGDNTRAALMTRGMAEIARLGVALGGKVLTFAGLSGI
GDLIVTCTSMYSRNRRAGILLGKGQSLEEVLDAVGMVVEGVRTTAAARELACQHGIKMPITEEIYQVLYKGKPVGDCVAA
LMERPRTHEVESGDW

Sequences:

>Translated_335_residues
MKESIAVLGAGSWGTALAVLLAHKGFRVNLWARRPELATALRETGENKTYLPGVRLTGTIIPTADLPAAVKGAGLVVLSV
PSHAVRSTARLLKPFLPKGTVVVNTAKGLELETKKRLSQVLVEEGLDRVAVLSGPSHAEEVGRGLPTTVVVAAADRETAE
YVQDVFMDPTFRVYTNPDIIGVEFGGALKNIIALATGMADGLGLGDNTRAALMTRGMAEIARLGVALGGKVLTFAGLSGI
GDLIVTCTSMYSRNRRAGILLGKGQSLEEVLDAVGMVVEGVRTTAAARELACQHGIKMPITEEIYQVLYKGKPVGDCVAA
LMERPRTHEVESGDW
>Mature_335_residues
MKESIAVLGAGSWGTALAVLLAHKGFRVNLWARRPELATALRETGENKTYLPGVRLTGTIIPTADLPAAVKGAGLVVLSV
PSHAVRSTARLLKPFLPKGTVVVNTAKGLELETKKRLSQVLVEEGLDRVAVLSGPSHAEEVGRGLPTTVVVAAADRETAE
YVQDVFMDPTFRVYTNPDIIGVEFGGALKNIIALATGMADGLGLGDNTRAALMTRGMAEIARLGVALGGKVLTFAGLSGI
GDLIVTCTSMYSRNRRAGILLGKGQSLEEVLDAVGMVVEGVRTTAAARELACQHGIKMPITEEIYQVLYKGKPVGDCVAA
LMERPRTHEVESGDW

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=346, Percent_Identity=28.6127167630058, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=29.512893982808, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=44.8795180722892, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17507425, Length=280, Percent_Identity=29.2857142857143, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32564399, Length=329, Percent_Identity=28.2674772036474, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193210136, Length=338, Percent_Identity=27.810650887574, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32564403, Length=338, Percent_Identity=27.810650887574, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=326, Percent_Identity=25.4601226993865, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=27.4566473988439, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320181, Length=359, Percent_Identity=27.0194986072423, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136202, Length=347, Percent_Identity=26.8011527377522, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136200, Length=347, Percent_Identity=26.8011527377522, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136204, Length=347, Percent_Identity=26.8011527377522, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI22026922, Length=344, Percent_Identity=25, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281362270, Length=287, Percent_Identity=28.2229965156794, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45551945, Length=287, Percent_Identity=28.2229965156794, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24648969, Length=275, Percent_Identity=27.6363636363636, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_MOOTA (Q2RIV6)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430176.1
- ProteinModelPortal:   Q2RIV6
- SMR:   Q2RIV6
- STRING:   Q2RIV6
- GeneID:   3831030
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1320
- NMPDR:   fig|264732.9.peg.1315
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   Q2RIV6
- BioCyc:   MTHE264732:MOTH_1320-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35391; Mature: 35391

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 189-189 BINDING 107-107 BINDING 107-107 BINDING 138-138 BINDING 253-253 BINDING 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESIAVLGAGSWGTALAVLLAHKGFRVNLWARRPELATALRETGENKTYLPGVRLTGTI
CCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEECCCCEEEEEE
IPTADLPAAVKGAGLVVLSVPSHAVRSTARLLKPFLPKGTVVVNTAKGLELETKKRLSQV
ECCCCCCCHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHH
LVEEGLDRVAVLSGPSHAEEVGRGLPTTVVVAAADRETAEYVQDVFMDPTFRVYTNPDII
HHHCCCCEEEEECCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCEE
GVEFGGALKNIIALATGMADGLGLGDNTRAALMTRGMAEIARLGVALGGKVLTFAGLSGI
EEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEHHCCCHH
GDLIVTCTSMYSRNRRAGILLGKGQSLEEVLDAVGMVVEGVRTTAAARELACQHGIKMPI
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TEEIYQVLYKGKPVGDCVAALMERPRTHEVESGDW
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKESIAVLGAGSWGTALAVLLAHKGFRVNLWARRPELATALRETGENKTYLPGVRLTGTI
CCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEECCCCEEEEEE
IPTADLPAAVKGAGLVVLSVPSHAVRSTARLLKPFLPKGTVVVNTAKGLELETKKRLSQV
ECCCCCCCHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHH
LVEEGLDRVAVLSGPSHAEEVGRGLPTTVVVAAADRETAEYVQDVFMDPTFRVYTNPDII
HHHCCCCEEEEECCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCEE
GVEFGGALKNIIALATGMADGLGLGDNTRAALMTRGMAEIARLGVALGGKVLTFAGLSGI
EEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEHHCCCHH
GDLIVTCTSMYSRNRRAGILLGKGQSLEEVLDAVGMVVEGVRTTAAARELACQHGIKMPI
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TEEIYQVLYKGKPVGDCVAALMERPRTHEVESGDW
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA