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The map label for this gene is metX

Identifier: 83590155

GI number: 83590155

Start: 1351668

End: 1352792

Strand: Reverse

Name: metX

Synonym: Moth_1308

Alternate gene names: 83590155

Gene position: 1352792-1351668 (Counterclockwise)

Preceding gene: 83590156

Following gene: 83590154

Centisome position: 51.46

GC content: 57.51

Gene sequence:

>1125_bases
ATGGATGGAGTCGGTATTGTAACAACCAGGTTTTATGAATGGTCGCAATGCCTCCACCTGGAAAGCGGGGCCCAGCTGGG
CTCCCTTACCATAGCCTATGAGACCTATGGGGAACTGAACGCGGCCGGAAATAACGCCATCCTGGTCCTCCACGCCCTTA
CCGGTAATGCCCATATCGCCGGCCGAAATTTTCCGGACGAGAGGTATCCCGGCTGGTGGGACCCCCTGGTAGGGCCGGGC
CGGGCCCTGGACACCAGGCGCTATTTCATTGTCTGTGCCAACGTCCTGGGAAGCTGCTATGGTACCACCGGGCCGGCCAG
CATTAATCCAGCCACCGGCAAGCCCTACGGGATGGATTTTCCGGCCATCACTATCCGCGATATGGTACGGGCACAAAAAA
TCCTCCTTGACTATCTGGGGGTCAAGCGCCTGGTGGCGGCCATCGGTGGTTCCATGGGCGGGATGCAGGTCCTGGAGTGG
GGTTTTCTTTATCCTCAGATGCTGGACGCCATTATTCCCATTGCCACCTGCGGCCGGACTACTCCCATGCAGATTGCCTT
TCACCACGTGCAGCGGGAAGCCATTTACGCCGACCCCGACTGGCAGGGAGGCAATTATTACGGCACTGCCGGGCCCCGGC
GGGGACTGGCCCTGGCCCGGCAGATCGGGATTATTACTTATAAAAGCGACCCCTCCTGGAACATGAAATTTGGCCGCAAC
CTGGTGGACCCCCGGAAATACTTCCAACTGGAAGGGCAGTTCGAAGTAGAGAGCTACCTGGCCTACCAGGGGAGGAAGCT
GGTAGATCGTTTCGACGCCAACTCTTACCTGTACCTTACCAAAGCAGTAGACCTCCACGATGTGAGCCAGGGACGGGGAA
GCTATAATGAAGTCTGGCGGGATTTCCCCTGCCCCTGCCTGGGTATAGGCATATCAAGCGATTTTCTTTTCCCTCCCTAT
CAGGTGCAGGAGATTGTCCGGATGATTAACGACGGCGGCGGCCATGCCCGTTACGCAGAGATTGATTCCCCCTATGGCCA
CGACGCCTTTTTAATCGAGTTTAACCAGCTGGCAGCCATTATCCAGCCGTTTCTGAAAGAGTTGCGCCCGGACCTGGCCG
CTTGA

Upstream 100 bases:

>100_bases
TCGGGTGTTACCGAAGATCTGGTCCGCATCTCCGTGGGCCTGGAGGACGTAGAAGACCTGATTGCCGACCTGGACCAGGC
ATTAAACAGGAGCCGGTAGC

Downstream 100 bases:

>100_bases
AAGGTGAGTTCTTCCAATTATGGTTTGCCTGCCAAGAACCACCGGAGCCCGGAAGCCTTTAGCAAAAAGACAGAAGAAAC
AAGTCCATAGGACAGTGAAT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDGVGIVTTRFYEWSQCLHLESGAQLGSLTIAYETYGELNAAGNNAILVLHALTGNAHIAGRNFPDERYPGWWDPLVGPG
RALDTRRYFIVCANVLGSCYGTTGPASINPATGKPYGMDFPAITIRDMVRAQKILLDYLGVKRLVAAIGGSMGGMQVLEW
GFLYPQMLDAIIPIATCGRTTPMQIAFHHVQREAIYADPDWQGGNYYGTAGPRRGLALARQIGIITYKSDPSWNMKFGRN
LVDPRKYFQLEGQFEVESYLAYQGRKLVDRFDANSYLYLTKAVDLHDVSQGRGSYNEVWRDFPCPCLGIGISSDFLFPPY
QVQEIVRMINDGGGHARYAEIDSPYGHDAFLIEFNQLAAIIQPFLKELRPDLAA

Sequences:

>Translated_374_residues
MDGVGIVTTRFYEWSQCLHLESGAQLGSLTIAYETYGELNAAGNNAILVLHALTGNAHIAGRNFPDERYPGWWDPLVGPG
RALDTRRYFIVCANVLGSCYGTTGPASINPATGKPYGMDFPAITIRDMVRAQKILLDYLGVKRLVAAIGGSMGGMQVLEW
GFLYPQMLDAIIPIATCGRTTPMQIAFHHVQREAIYADPDWQGGNYYGTAGPRRGLALARQIGIITYKSDPSWNMKFGRN
LVDPRKYFQLEGQFEVESYLAYQGRKLVDRFDANSYLYLTKAVDLHDVSQGRGSYNEVWRDFPCPCLGIGISSDFLFPPY
QVQEIVRMINDGGGHARYAEIDSPYGHDAFLIEFNQLAAIIQPFLKELRPDLAA
>Mature_374_residues
MDGVGIVTTRFYEWSQCLHLESGAQLGSLTIAYETYGELNAAGNNAILVLHALTGNAHIAGRNFPDERYPGWWDPLVGPG
RALDTRRYFIVCANVLGSCYGTTGPASINPATGKPYGMDFPAITIRDMVRAQKILLDYLGVKRLVAAIGGSMGGMQVLEW
GFLYPQMLDAIIPIATCGRTTPMQIAFHHVQREAIYADPDWQGGNYYGTAGPRRGLALARQIGIITYKSDPSWNMKFGRN
LVDPRKYFQLEGQFEVESYLAYQGRKLVDRFDANSYLYLTKAVDLHDVSQGRGSYNEVWRDFPCPCLGIGISSDFLFPPY
QVQEIVRMINDGGGHARYAEIDSPYGHDAFLIEFNQLAAIIQPFLKELRPDLAA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=223, Percent_Identity=42.6008968609865, Blast_Score=185, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_MOOTA (Q2RIW8)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430164.1
- ProteinModelPortal:   Q2RIW8
- SMR:   Q2RIW8
- STRING:   Q2RIW8
- GeneID:   3831794
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1308
- NMPDR:   fig|264732.9.peg.1302
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q2RIW8
- ProtClustDB:   CLSK941146
- BioCyc:   MTHE264732:MOTH_1308-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41586; Mature: 41586

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: ACT_SITE 151-151 ACT_SITE 347-347

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVGIVTTRFYEWSQCLHLESGAQLGSLTIAYETYGELNAAGNNAILVLHALTGNAHIA
CCCCEEEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCEEEE
GRNFPDERYPGWWDPLVGPGRALDTRRYFIVCANVLGSCYGTTGPASINPATGKPYGMDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PAITIRDMVRAQKILLDYLGVKRLVAAIGGSMGGMQVLEWGFLYPQMLDAIIPIATCGRT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TPMQIAFHHVQREAIYADPDWQGGNYYGTAGPRRGLALARQIGIITYKSDPSWNMKFGRN
CHHHHHHHHHHHHEEECCCCCCCCCEECCCCCHHHHHHHHHEEEEEECCCCCCCHHHCCC
LVDPRKYFQLEGQFEVESYLAYQGRKLVDRFDANSYLYLTKAVDLHDVSQGRGSYNEVWR
CCCCHHHEEECCCCCHHHHHHHCCHHHHHHHCCCCEEEEEEECCHHHHHCCCCCHHHHHH
DFPCPCLGIGISSDFLFPPYQVQEIVRMINDGGGHARYAEIDSPYGHDAFLIEFNQLAAI
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHHHH
IQPFLKELRPDLAA
HHHHHHHHCHHHCC
>Mature Secondary Structure
MDGVGIVTTRFYEWSQCLHLESGAQLGSLTIAYETYGELNAAGNNAILVLHALTGNAHIA
CCCCEEEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCEEEE
GRNFPDERYPGWWDPLVGPGRALDTRRYFIVCANVLGSCYGTTGPASINPATGKPYGMDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PAITIRDMVRAQKILLDYLGVKRLVAAIGGSMGGMQVLEWGFLYPQMLDAIIPIATCGRT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TPMQIAFHHVQREAIYADPDWQGGNYYGTAGPRRGLALARQIGIITYKSDPSWNMKFGRN
CHHHHHHHHHHHHEEECCCCCCCCCEECCCCCHHHHHHHHHEEEEEECCCCCCCHHHCCC
LVDPRKYFQLEGQFEVESYLAYQGRKLVDRFDANSYLYLTKAVDLHDVSQGRGSYNEVWR
CCCCHHHEEECCCCCHHHHHHHCCHHHHHHHCCCCEEEEEEECCHHHHHCCCCCHHHHHH
DFPCPCLGIGISSDFLFPPYQVQEIVRMINDGGGHARYAEIDSPYGHDAFLIEFNQLAAI
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHHHH
IQPFLKELRPDLAA
HHHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA