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The map label for this gene is yugH [H]

Identifier: 83590036

GI number: 83590036

Start: 1220262

End: 1221476

Strand: Reverse

Name: yugH [H]

Synonym: Moth_1188

Alternate gene names: 83590036

Gene position: 1221476-1220262 (Counterclockwise)

Preceding gene: 83590037

Following gene: 83590035

Centisome position: 46.47

GC content: 58.19

Gene sequence:

>1215_bases
ATGACCATTGCCCACGGTTTTGAAGCCAGGCGTTTTATCACACCGGTGGTTAGGGATCTGCCGCCTTCAGGAATCCGCCG
CTTTTTTGAACTGGTAGCCAGCACCAAGGGCGTAATCTCCCTCGGGGTGGGAGAACCAGATTTCGTCACTCCCTGGCATA
TCCGGGAGGCCTGCGTCCAATCCCTGGAACGGGGCTATACCATGTACACCTCCAACTACGGCCTGCCCGAACTGCGCCGG
GCCATAGCCGATTACCTGGCCTGGCGTTTCGGCTTGACCTATGATCCCATGAAGCAGATTATGGTGACCATTGGTGCCAG
TGAAGCAGTCGACCTGGCACTGCGGACGGTATTGAACCCCGGGGATGAAGTCTTGATCCCCGAGCCCTGTTATGTTTCCT
ACCAGCCCATAACGCAACTGGCGGGGGGTATCCCGGTCCCTATCCCGACGACAATGACTGACGGTTTTGCCCTTACGGCC
GCCCGCCTGGAGCACTACATTACCCCCCGGAGTAAAGTCTTGATTCTTTGCTTTCCCAATAACCCGACCGGCGCCGTCCT
CAGCCGGGAGGAGATGCAGGCCATTGCCCGGCTGGTTGAAAAGTACAACCTGCTGGTGATCAGCGATGAAATCTATGCAG
AATTGCGTTATGAGGGCCAACCGTTATCCTTTGCCTCTCTGCCCGGCATGCAGGAGCGCACCATCCTGGTGAGCGGTTTT
TCCAAGGCCTTTGCCATGACCGGATGGCGCATCGGTTATGTAGCGGCTCATCCCGATTTTCTGGCAGCTATGGTTAAAAT
CCACCAGTATACCATCCTCTGCGCTCCCGTCATGGGTCAGATGGCGGCCCTGGAAGCCCTGCGCCACGGCCGCCAGGACG
TGGAGAGGATGGTGGAGCAATACGACCAGCGACGGCGCCTGGTTTACAGCCGGCTGCGGGAGATGGGCCTGGATTGTTTT
GAACCCCGGGGGGCCTTTTACATCTTCCCCTCCATAGCTGCCACCGGCCTGGATTCCGTCACTTTCGCCGAAGAGCTTCT
TAAGGAAGAAAAGGTGGCCGTAGTACCGGGTACAGCCTTTGGCGCCAGTGGCGAAGGTTTTATCCGCTGTTCCTATGCCG
CCTCCCTGGCCGACCTGACAGAAGCCATGAATCGCATGGAACGCTTTGTCGCCCGGCGTCTGGCCTTTAACCAGCGGGCC
GTAGCCCAGGCTTAA

Upstream 100 bases:

>100_bases
ACGTCCAGAGTACCATGACCCATTTCATCCTTAAAAGGTATAAACAGGATGGCGTCATTTTTGAAGATCAAGAAGCAGAC
CGGAGGCAGGCGTTGCAACC

Downstream 100 bases:

>100_bases
AAGAAAAAATTATTTCCGGGAGAGGAATTATGATTAAATTACAGTTTTGCGGCGCTGCTGGAACGGTTACCGGTTCCTGT
TACCTCCTTGATACCGGCCG

Product: aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTIAHGFEARRFITPVVRDLPPSGIRRFFELVASTKGVISLGVGEPDFVTPWHIREACVQSLERGYTMYTSNYGLPELRR
AIADYLAWRFGLTYDPMKQIMVTIGASEAVDLALRTVLNPGDEVLIPEPCYVSYQPITQLAGGIPVPIPTTMTDGFALTA
ARLEHYITPRSKVLILCFPNNPTGAVLSREEMQAIARLVEKYNLLVISDEIYAELRYEGQPLSFASLPGMQERTILVSGF
SKAFAMTGWRIGYVAAHPDFLAAMVKIHQYTILCAPVMGQMAALEALRHGRQDVERMVEQYDQRRRLVYSRLREMGLDCF
EPRGAFYIFPSIAATGLDSVTFAEELLKEEKVAVVPGTAFGASGEGFIRCSYAASLADLTEAMNRMERFVARRLAFNQRA
VAQA

Sequences:

>Translated_404_residues
MTIAHGFEARRFITPVVRDLPPSGIRRFFELVASTKGVISLGVGEPDFVTPWHIREACVQSLERGYTMYTSNYGLPELRR
AIADYLAWRFGLTYDPMKQIMVTIGASEAVDLALRTVLNPGDEVLIPEPCYVSYQPITQLAGGIPVPIPTTMTDGFALTA
ARLEHYITPRSKVLILCFPNNPTGAVLSREEMQAIARLVEKYNLLVISDEIYAELRYEGQPLSFASLPGMQERTILVSGF
SKAFAMTGWRIGYVAAHPDFLAAMVKIHQYTILCAPVMGQMAALEALRHGRQDVERMVEQYDQRRRLVYSRLREMGLDCF
EPRGAFYIFPSIAATGLDSVTFAEELLKEEKVAVVPGTAFGASGEGFIRCSYAASLADLTEAMNRMERFVARRLAFNQRA
VAQA
>Mature_403_residues
TIAHGFEARRFITPVVRDLPPSGIRRFFELVASTKGVISLGVGEPDFVTPWHIREACVQSLERGYTMYTSNYGLPELRRA
IADYLAWRFGLTYDPMKQIMVTIGASEAVDLALRTVLNPGDEVLIPEPCYVSYQPITQLAGGIPVPIPTTMTDGFALTAA
RLEHYITPRSKVLILCFPNNPTGAVLSREEMQAIARLVEKYNLLVISDEIYAELRYEGQPLSFASLPGMQERTILVSGFS
KAFAMTGWRIGYVAAHPDFLAAMVKIHQYTILCAPVMGQMAALEALRHGRQDVERMVEQYDQRRRLVYSRLREMGLDCFE
PRGAFYIFPSIAATGLDSVTFAEELLKEEKVAVVPGTAFGASGEGFIRCSYAASLADLTEAMNRMERFVARRLAFNQRAV
AQA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=325, Percent_Identity=32.6153846153846, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI169881279, Length=325, Percent_Identity=32.6153846153846, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=28.9002557544757, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=28.9002557544757, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI169881281, Length=228, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=25.5208333333333, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI187936925, Length=390, Percent_Identity=28.7179487179487, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI14211921, Length=390, Percent_Identity=28.7179487179487, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI19263340, Length=368, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI149944424, Length=394, Percent_Identity=24.8730964467005, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4885351, Length=379, Percent_Identity=25.065963060686, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=31.25, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=29.2553191489362, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1788627, Length=372, Percent_Identity=28.7634408602151, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790797, Length=303, Percent_Identity=26.0726072607261, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787909, Length=345, Percent_Identity=25.2173913043478, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787710, Length=330, Percent_Identity=25.1515151515152, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788332, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=377, Percent_Identity=30.7692307692308, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71994472, Length=377, Percent_Identity=30.7692307692308, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17567369, Length=376, Percent_Identity=27.9255319148936, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17567663, Length=390, Percent_Identity=26.9230769230769, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71981209, Length=340, Percent_Identity=23.8235294117647, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=158, Percent_Identity=27.8481012658228, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=323, Percent_Identity=26.9349845201238, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=353, Percent_Identity=26.3456090651558, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=369, Percent_Identity=25.7452574525745, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=26.9430051813472, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=26.9430051813472, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=26.9430051813472, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=26.9430051813472, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=23.5602094240838, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641770, Length=340, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24641760, Length=340, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24641768, Length=340, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24641766, Length=340, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24641764, Length=340, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI45551451, Length=340, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 45016; Mature: 44885

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAHGFEARRFITPVVRDLPPSGIRRFFELVASTKGVISLGVGEPDFVTPWHIREACVQ
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
SLERGYTMYTSNYGLPELRRAIADYLAWRFGLTYDPMKQIMVTIGASEAVDLALRTVLNP
HHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCC
GDEVLIPEPCYVSYQPITQLAGGIPVPIPTTMTDGFALTAARLEHYITPRSKVLILCFPN
CCCEECCCCCEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
NPTGAVLSREEMQAIARLVEKYNLLVISDEIYAELRYEGQPLSFASLPGMQERTILVSGF
CCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHHHEECCCCCCHHCCCCCCCCEEEEECH
SKAFAMTGWRIGYVAAHPDFLAAMVKIHQYTILCAPVMGQMAALEALRHGRQDVERMVEQ
HHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YDQRRRLVYSRLREMGLDCFEPRGAFYIFPSIAATGLDSVTFAEELLKEEKVAVVPGTAF
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHCCCCHHHHHHHHHHCCCEEEECCCCC
GASGEGFIRCSYAASLADLTEAMNRMERFVARRLAFNQRAVAQA
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
TIAHGFEARRFITPVVRDLPPSGIRRFFELVASTKGVISLGVGEPDFVTPWHIREACVQ
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
SLERGYTMYTSNYGLPELRRAIADYLAWRFGLTYDPMKQIMVTIGASEAVDLALRTVLNP
HHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCC
GDEVLIPEPCYVSYQPITQLAGGIPVPIPTTMTDGFALTAARLEHYITPRSKVLILCFPN
CCCEECCCCCEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
NPTGAVLSREEMQAIARLVEKYNLLVISDEIYAELRYEGQPLSFASLPGMQERTILVSGF
CCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHHHEECCCCCCHHCCCCCCCCEEEEECH
SKAFAMTGWRIGYVAAHPDFLAAMVKIHQYTILCAPVMGQMAALEALRHGRQDVERMVEQ
HHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YDQRRRLVYSRLREMGLDCFEPRGAFYIFPSIAATGLDSVTFAEELLKEEKVAVVPGTAF
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHCCCCHHHHHHHHHHCCCEEEECCCCC
GASGEGFIRCSYAASLADLTEAMNRMERFVARRLAFNQRAVAQA
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]