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The map label for this gene is ubiE [H]

Identifier: 83590024

GI number: 83590024

Start: 1207242

End: 1207934

Strand: Reverse

Name: ubiE [H]

Synonym: Moth_1176

Alternate gene names: 83590024

Gene position: 1207934-1207242 (Counterclockwise)

Preceding gene: 83590025

Following gene: 83590023

Centisome position: 45.95

GC content: 57.72

Gene sequence:

>693_bases
ATGGCTGAAATCTTTGATCGTAAAGCCGGGGATTACGACGACTGGTATACGCGTCCCCTGGGAGCCCTGGTCGACCGGGT
GGAAAAGGAGCCTATCTATGCTTACCTGGACCCCCATGCCGGAGAACATATCCTAGACGTCGGCTGTGGTACCGGTAACT
TCTCCCTGGAACTGGCCCGCAGGGGCGTAAAGGTGACGGGTATCGACATATCTGATCCCATGCTGGCCAAAGCCAGGAAA
AAGGCGGCCGACGCTGGCCTGGCGATTGAGTTTCTCCATGCCGACGCCATGAATTTGCCCTTTGGCGATAATACCTTTGA
CAAGATAGTATCGGTTACGGCCCTGGAGTTTGCCCCGGATTTAAAGGCCGTCCTGGAAGAGAGTTACCGCGTGTTGAAGC
CCGGGGGGAGGATGGTCATCGGCCTCATCGGCGGCAACAGCCTCTGGAGCCGCCATTATGAGGCCCGGGCAGCCCGGGAG
CCGGATTGTCTCTTCCGGTACGCCAGATTCTACACCCTGGACGAACTTCTGGCCGCCATGCCCGGTAAAAACGTCCAGGG
TAAAGCCGTCCTCTTCTTTGGCCCTGACTTCGACGGCACCAAAGTCGATGAAGCCCTGGCCATCGAGGCTGCCGCCGCCC
GTGAGGGTCGTACCAATGGTGGCTTTATCACCGCTGTGAGTTATAAAGACTAA

Upstream 100 bases:

>100_bases
TTACTTGCCAGGGAAGAGGAAAAAAGCCGTTGAGGGCGAATATGGTATACCAGAGGTAAAAGGCGCCGGTAAAACTTTTC
CCTGAAAGGGGTTGGCAACT

Downstream 100 bases:

>100_bases
AGAGGCCAGCCAAAGATGATTATCAAAGTATTGCCCCTTCCGGAGTATTACCACGGGAGGGGTGTTTTTTGTCCCTTTAG
GTTATTTAACCTTGACGCCT

Product: UbiE/COQ5 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAEIFDRKAGDYDDWYTRPLGALVDRVEKEPIYAYLDPHAGEHILDVGCGTGNFSLELARRGVKVTGIDISDPMLAKARK
KAADAGLAIEFLHADAMNLPFGDNTFDKIVSVTALEFAPDLKAVLEESYRVLKPGGRMVIGLIGGNSLWSRHYEARAARE
PDCLFRYARFYTLDELLAAMPGKNVQGKAVLFFGPDFDGTKVDEALAIEAAAAREGRTNGGFITAVSYKD

Sequences:

>Translated_230_residues
MAEIFDRKAGDYDDWYTRPLGALVDRVEKEPIYAYLDPHAGEHILDVGCGTGNFSLELARRGVKVTGIDISDPMLAKARK
KAADAGLAIEFLHADAMNLPFGDNTFDKIVSVTALEFAPDLKAVLEESYRVLKPGGRMVIGLIGGNSLWSRHYEARAARE
PDCLFRYARFYTLDELLAAMPGKNVQGKAVLFFGPDFDGTKVDEALAIEAAAAREGRTNGGFITAVSYKD
>Mature_229_residues
AEIFDRKAGDYDDWYTRPLGALVDRVEKEPIYAYLDPHAGEHILDVGCGTGNFSLELARRGVKVTGIDISDPMLAKARKK
AADAGLAIEFLHADAMNLPFGDNTFDKIVSVTALEFAPDLKAVLEESYRVLKPGGRMVIGLIGGNSLWSRHYEARAAREP
DCLFRYARFYTLDELLAAMPGKNVQGKAVLFFGPDFDGTKVDEALAIEAAAAREGRTNGGFITAVSYKD

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=164, Percent_Identity=32.3170731707317, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994983, Length=105, Percent_Identity=38.0952380952381, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25143945, Length=127, Percent_Identity=34.6456692913386, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561380, Length=110, Percent_Identity=33.6363636363636, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323635, Length=103, Percent_Identity=40.7766990291262, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014122
- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: NA

Molecular weight: Translated: 25168; Mature: 25037

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIFDRKAGDYDDWYTRPLGALVDRVEKEPIYAYLDPHAGEHILDVGCGTGNFSLELAR
CCCCCCCCCCCCCHHHHCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCEEHHHHH
RGVKVTGIDISDPMLAKARKKAADAGLAIEFLHADAMNLPFGDNTFDKIVSVTALEFAPD
CCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCH
LKAVLEESYRVLKPGGRMVIGLIGGNSLWSRHYEARAAREPDCLFRYARFYTLDELLAAM
HHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
PGKNVQGKAVLFFGPDFDGTKVDEALAIEAAAAREGRTNGGFITAVSYKD
CCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
AEIFDRKAGDYDDWYTRPLGALVDRVEKEPIYAYLDPHAGEHILDVGCGTGNFSLELAR
CCCCCCCCCCCCHHHHCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCEEHHHHH
RGVKVTGIDISDPMLAKARKKAADAGLAIEFLHADAMNLPFGDNTFDKIVSVTALEFAPD
CCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCH
LKAVLEESYRVLKPGGRMVIGLIGGNSLWSRHYEARAAREPDCLFRYARFYTLDELLAAM
HHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
PGKNVQGKAVLFFGPDFDGTKVDEALAIEAAAAREGRTNGGFITAVSYKD
CCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]