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The map label for this gene is asrC [H]

Identifier: 83590016

GI number: 83590016

Start: 1199708

End: 1200691

Strand: Reverse

Name: asrC [H]

Synonym: Moth_1168

Alternate gene names: 83590016

Gene position: 1200691-1199708 (Counterclockwise)

Preceding gene: 83590017

Following gene: 83590014

Centisome position: 45.67

GC content: 58.94

Gene sequence:

>984_bases
ATGTATAATACGAAAGAATTGATCAAGAACGCCTACCGCATTACCAGCCGCAGGGGTTATACGGCCCTGCGTCTCCGGGT
GCCCGGCGGGCACCTGGCGGCCGAATATTTAGGCTTAATCCAGGATATAGCCCGGCGCTACGGCAACGGTACCGTTCATC
TGACTACCCGCCAGGGTTTTGAAATCCCCGGCATACCCCTTGACAAAGTACCGGAGGTAAACCAACTGCTGGCACCTATG
TTGCAACAAGAGGCCGCCCTGGGAGTGGCCATCGAGAATATCCATGCCGGTTACCCGGCGGCGGGCACCCGGAACGTCAC
GGCCTGCATTGGCAGCAGAGTCTGCCCCTTTGCCAACTTTGACACCACGGCCCTGGCGCAAAAAATCGAAGGTCTCATCT
ATCCCAACCACTACCACGTCAAGATTGCCATTACCGGTTGCCCCAACGACTGCATCAAGGCCCACCTCCAGGACATCGGC
ATCATCGGCCAGGTGGAGCCGGAGTATGATCCCGGCCGCTGTATCGCCTGCCAGGCTTGTGTCAAGAACTGCCGCCAGTT
TATCGTCGGCGCCCTGGAGCTGGTCAATTACCAGGTGGAACGCGACGGCAAGCGCTGCCTGGGCTGCGGCGAGTGTATCC
TGCAATGTCCCATGGCGGCCTGGACCAGGGGGCGCCAGTACTACCGGATCGTGGCCCTGGGTCGCACCGGGAAAAAGAGC
CCGCGCCTGGCGGCCAACTTCCTGGAATGTATTGATGAAAAGGCCGTCCTGCAGGTAATCGCCAACCTGTACCGTTATAT
TGAGCGGCACATTGATCGCTCCCTGCCCAAGGAGCACGTTGGCTATATCGTCGACCGCACGGGCTACCAGGTCTTTAGGG
ATGAACTCCTGGATGGTGTTGATCTGGGTCCGAAAGGCCGGGTGGCCCGGGAATTGCCCTTTTACGGCTACAGCTACGAC
CGCGACTTGCTGTGGAGCAAATAG

Upstream 100 bases:

>100_bases
GCGGTCACTGCAAGATCAACGACGTATACGTTTGCCTGGAAGGGCCGGTGTTTAACTATAGCCGGGCCCGGGACCTGGTC
GACTGAAGGAGGAGGGAGCC

Downstream 100 bases:

>100_bases
TTGGGGTGCCAGTTATACCATGATATGACTTCAAGACCTACTGGCAACCGAAGATAGGTGAGGTAATTATTAAATAACGG
CATACAGAGCGGCGGCGACG

Product: nitrite and sulphite reductase 4Fe-4S region

Products: 3 NAD(P)+; NH4OH; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MYNTKELIKNAYRITSRRGYTALRLRVPGGHLAAEYLGLIQDIARRYGNGTVHLTTRQGFEIPGIPLDKVPEVNQLLAPM
LQQEAALGVAIENIHAGYPAAGTRNVTACIGSRVCPFANFDTTALAQKIEGLIYPNHYHVKIAITGCPNDCIKAHLQDIG
IIGQVEPEYDPGRCIACQACVKNCRQFIVGALELVNYQVERDGKRCLGCGECILQCPMAAWTRGRQYYRIVALGRTGKKS
PRLAANFLECIDEKAVLQVIANLYRYIERHIDRSLPKEHVGYIVDRTGYQVFRDELLDGVDLGPKGRVARELPFYGYSYD
RDLLWSK

Sequences:

>Translated_327_residues
MYNTKELIKNAYRITSRRGYTALRLRVPGGHLAAEYLGLIQDIARRYGNGTVHLTTRQGFEIPGIPLDKVPEVNQLLAPM
LQQEAALGVAIENIHAGYPAAGTRNVTACIGSRVCPFANFDTTALAQKIEGLIYPNHYHVKIAITGCPNDCIKAHLQDIG
IIGQVEPEYDPGRCIACQACVKNCRQFIVGALELVNYQVERDGKRCLGCGECILQCPMAAWTRGRQYYRIVALGRTGKKS
PRLAANFLECIDEKAVLQVIANLYRYIERHIDRSLPKEHVGYIVDRTGYQVFRDELLDGVDLGPKGRVARELPFYGYSYD
RDLLWSK
>Mature_327_residues
MYNTKELIKNAYRITSRRGYTALRLRVPGGHLAAEYLGLIQDIARRYGNGTVHLTTRQGFEIPGIPLDKVPEVNQLLAPM
LQQEAALGVAIENIHAGYPAAGTRNVTACIGSRVCPFANFDTTALAQKIEGLIYPNHYHVKIAITGCPNDCIKAHLQDIG
IIGQVEPEYDPGRCIACQACVKNCRQFIVGALELVNYQVERDGKRCLGCGECILQCPMAAWTRGRQYYRIVALGRTGKKS
PRLAANFLECIDEKAVLQVIANLYRYIERHIDRSLPKEHVGYIVDRTGYQVFRDELLDGVDLGPKGRVARELPFYGYSYD
RDLLWSK

Specific function: This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine [H]

COG id: COG2221

COG function: function code C; Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066
- InterPro:   IPR014261 [H]

Pfam domain/function: PF00037 Fer4; PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: 1.7.1.4 [C]

Molecular weight: Translated: 36617; Mature: 36617

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00365 NIR_SIR ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNTKELIKNAYRITSRRGYTALRLRVPGGHLAAEYLGLIQDIARRYGNGTVHLTTRQGF
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
EIPGIPLDKVPEVNQLLAPMLQQEAALGVAIENIHAGYPAAGTRNVTACIGSRVCPFANF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCC
DTTALAQKIEGLIYPNHYHVKIAITGCPNDCIKAHLQDIGIIGQVEPEYDPGRCIACQAC
CHHHHHHHHCCEECCCEEEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHH
VKNCRQFIVGALELVNYQVERDGKRCLGCGECILQCPMAAWTRGRQYYRIVALGRTGKKS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCEEEEEEEECCCCCCC
PRLAANFLECIDEKAVLQVIANLYRYIERHIDRSLPKEHVGYIVDRTGYQVFRDELLDGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEECCCHHHHHHHHHCCC
DLGPKGRVARELPFYGYSYDRDLLWSK
CCCCCCCCHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYNTKELIKNAYRITSRRGYTALRLRVPGGHLAAEYLGLIQDIARRYGNGTVHLTTRQGF
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
EIPGIPLDKVPEVNQLLAPMLQQEAALGVAIENIHAGYPAAGTRNVTACIGSRVCPFANF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCC
DTTALAQKIEGLIYPNHYHVKIAITGCPNDCIKAHLQDIGIIGQVEPEYDPGRCIACQAC
CHHHHHHHHCCEECCCEEEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHH
VKNCRQFIVGALELVNYQVERDGKRCLGCGECILQCPMAAWTRGRQYYRIVALGRTGKKS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCEEEEEEEECCCCCCC
PRLAANFLECIDEKAVLQVIANLYRYIERHIDRSLPKEHVGYIVDRTGYQVFRDELLDGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEECCCHHHHHHHHHCCC
DLGPKGRVARELPFYGYSYDRDLLWSK
CCCCCCCCHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD; NAD+; NADH; Siroheme [C]

Metal ions: Iron [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.4 {NO2-}} 0.005 {NO2-}} 0.016 {NADH}} 5.3 {hydroxylamine}} [C]

Substrates: 3 NAD(P)H; nitrite [C]

Specific reaction: 3 NAD(P)H + nitrite = 3 NAD(P)+ + NH4OH + H2O [C]

General reaction: Redox reaction [C]

Inhibitor: 1, 10-Phenanthroline; 2, 2'-Bipyridine; Arsenite; CN-; NAD+; NADP+; NaN3; p-Chloromercuribenzoate; SO32- [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]