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The map label for this gene is fur [H]

Identifier: 83589995

GI number: 83589995

Start: 1178713

End: 1179180

Strand: Reverse

Name: fur [H]

Synonym: Moth_1147

Alternate gene names: 83589995

Gene position: 1179180-1178713 (Counterclockwise)

Preceding gene: 83589996

Following gene: 83589994

Centisome position: 44.86

GC content: 48.29

Gene sequence:

>468_bases
ATGAAAAATAAACTCAATGCTATCTGTCAAAAACTCCAACAATCGGAATATAAGGTAACGCCCCAGCGTCAGGTAATCCT
GAAAACCTTCCTTGAGCATGCCACTGAACACCTGAGCGCCGAGGAGGTCTACAATATTGTTAAAGGCCAGCATCCCGATA
TCGGCCTGGCTACCGTCTATCGTACCCTGGACCTCCTGGCCGAACTCGACATTTTAACCAAGATCAATTTTGGTGATGGC
CGCACCCGCTACGAAATGGTCCAGCACGAGGCCCATCACCATCACCATATGATCTGCCTGGGATGCGGCCGAGTTCAGGA
ATTTGACGCCGATTTACTGGAATCCCTGGAAAACTTGTTAACCAGAAAAACTGGTTTTCAGATCACCGACCACCAGTTGA
AATTCTACGGCTATTGTCGGGAATGTGCCGCTAAAAGCGAGGATAAGTCGGGTTCAGGAGATATTTGA

Upstream 100 bases:

>100_bases
CGTCACCAGGGTGAATTAAAAATTGCCACTCAACCGGAGCTGGCCCTGGCGGGCCAGGGGTTTACCGAAGCCCTGGCAGT
AATTAACGACCAGGTGTATC

Downstream 100 bases:

>100_bases
CGTACGATTATTGGCATATATGGAAGGAATTGTCATAGACAAGGGCGAAAAATAAGGACAGGATGGATATGAAAGGGAGC
GATGGAAATGTCCAGTCCTG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MKNKLNAICQKLQQSEYKVTPQRQVILKTFLEHATEHLSAEEVYNIVKGQHPDIGLATVYRTLDLLAELDILTKINFGDG
RTRYEMVQHEAHHHHHMICLGCGRVQEFDADLLESLENLLTRKTGFQITDHQLKFYGYCRECAAKSEDKSGSGDI

Sequences:

>Translated_155_residues
MKNKLNAICQKLQQSEYKVTPQRQVILKTFLEHATEHLSAEEVYNIVKGQHPDIGLATVYRTLDLLAELDILTKINFGDG
RTRYEMVQHEAHHHHHMICLGCGRVQEFDADLLESLENLLTRKTGFQITDHQLKFYGYCRECAAKSEDKSGSGDI
>Mature_155_residues
MKNKLNAICQKLQQSEYKVTPQRQVILKTFLEHATEHLSAEEVYNIVKGQHPDIGLATVYRTLDLLAELDILTKINFGDG
RTRYEMVQHEAHHHHHMICLGCGRVQEFDADLLESLENLLTRKTGFQITDHQLKFYGYCRECAAKSEDKSGSGDI

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=142, Percent_Identity=37.3239436619718, Blast_Score=99, Evalue=9e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17770; Mature: 17770

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLNAICQKLQQSEYKVTPQRQVILKTFLEHATEHLSAEEVYNIVKGQHPDIGLATVY
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHH
RTLDLLAELDILTKINFGDGRTRYEMVQHEAHHHHHMICLGCGRVQEFDADLLESLENLL
HHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHH
TRKTGFQITDHQLKFYGYCRECAAKSEDKSGSGDI
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKNKLNAICQKLQQSEYKVTPQRQVILKTFLEHATEHLSAEEVYNIVKGQHPDIGLATVY
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHH
RTLDLLAELDILTKINFGDGRTRYEMVQHEAHHHHHMICLGCGRVQEFDADLLESLENLL
HHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHH
TRKTGFQITDHQLKFYGYCRECAAKSEDKSGSGDI
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]