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The map label for this gene is fusA

Identifier: 83589990

GI number: 83589990

Start: 1173034

End: 1175076

Strand: Reverse

Name: fusA

Synonym: Moth_1142

Alternate gene names: 83589990

Gene position: 1175076-1173034 (Counterclockwise)

Preceding gene: 83589992

Following gene: 83589989

Centisome position: 44.7

GC content: 54.23

Gene sequence:

>2043_bases
ATGAAGGTTTACCCCAGTACCAGCATCAGGAACGTAGCTATAGTCGCCCACGGCGGTGCCGGTAAGACCAGCCTGACGGA
AGCGCTCCTTTATAACGCCGGTGCTACCAAACGCCTGGGGCGGGTTGACGAGGGTAATACTGTAACCGACTACCTTCCCG
AAGAAATTAAGCGCAAGGTTACTACCAACTCCGCATTGGCCGTGGCCGAGTGGCAGGATAATAAGATAAATCTACTGGAT
ACCCCCGGTTACAGTGACTTCTTTGGCGAGGTGGTAGGCGCCCTGCGGGTGGTAGATAGTCTGCTGGTAGTAGTTAGCGC
TGTGGCCGGGGTAGAGGTCCAGACAGAGGTTGTATGGGAAACGGCGGACAATCATCATCTGCCGCGGATCACCTATGTAA
ATAAAATGGACCGGGAGAACGCCAATTTCCAGAAAGCTGTGGAATCGATGCGAGAGCGTTTGAGCGGCCATATAGTCCCT
GTCCAGTTGCCCATAGGCGAGGCGGAAAACTTTACCGGAATTATCGATATCCTCAACCAAAAGGCCTATACCTACGATAA
CGGCAGTGAAAAAGAGATACCAGTTCCGGCGGAATATGCCGATGAGGTTGCCAGCCTGCGGGAAGCCTTGATTGAAGCTG
CTGCCGAAGGCGATGATGAACTGCTGATGAAATACCTGGACGGAAAAGAACTTTCCAGCGAAGAAATCCGCTCCGGCTTG
AAAAAAGCCGTTGCCGAAGGCAAGGCCATTCCTGTTCTCTGCGGCTCAGCCTGGAAGAATATGGCTGTCAAACCCGTCCT
GGACTATATAATAAACTACCTACCTTCCCCCGTTGAAGCTACCGGCAAGGATGCCGCCGCCCTCGAGGGTGAGAACCTGG
CTGCCCTGGTATTTAAGACCATAGCCGATCCCTATGTTGGTAAATTAAGCATGTTCCGGGTCTATAGCGGCGTTCTGAAA
TCCGACTCCACGGTCTACAACGTCAACCGGGAAAGCGAGGAAAAAATCGGCCAGCTCTTCTCCCTCCAGGGCAAAAACCA
GCTGCCGGTCACGGAGATGAAACCAGGGGATATAGGAGCTATAGCCAAACTCCAGGTTACCACCACCGGTGACACCCTTA
CCACCAAAGCCAACCCGGTCCGCCTGAAAGGTATTGACTTCCCGGAACCGACCCTGCCGGTGGCCATCAAACCTAAGAGC
AAGGGCGATGAAGATAAACTCAGCAACGCCCTGGCGCGGTTGCTGGAGGAAGACCCCACCCTGCGCCTGAACAAAAATAC
CGAGACCAGGGAAACCATCCTCACCGGAATGGGAGAATCCCACCTGGATATCACCCTGGAACGGCTGCAGCGCAAATTTG
GCGTGGAGGTGGAAATGAGCACCCCCACAGTACCTTACCGGGAAACCATTCGCGCCGCAGTTAACCATATAGAAGGTAAG
CATAAAAAACAAACGGGCGGCCACGGCCAGTACGGCCACGTCTTTATCGACATGGCTCCCCTGCCGGATAAGGAATTTGA
ATTCACCGAGACCATCTTCGGCGGCGCCGTGCCGCGCCAGTATATCCCGGCGGTTGAGAAGGGTATCCGCGAGGCCATGC
AGGAAGGCATCCTGGCCGGCTACCCGGTGACTAATATCAAGGTCAACCTGGCCGACGGTTCTTACCACCCGGTTGACTCC
TCTGAAATGGCTTTCAAGGTTGCTGCCGGCCTGGCCTTCCGCAAAGCAGTAGAACAGGCCAAACCGGTGTTGCTTGAGCC
CATAATGAACGTGGAGATAACGGTACCTGAACAGTTTATGGGCGACATTATGGGCGATTTAAACAGCCGCCGCGGCCGTA
TCCTGGGTATGGAACCCCAGGGTAAAAACCAGGTCATCCGCGCCCAGGTTCCCCTGGCAGAAATGTACCGTTACGCTATT
GACTTGAAGTCCATCACCCAGGCCCGCGGCCACTTTAAAATGGATTTTGCCCAGTACGAAGAGGTCCCGGCCAGCATTGC
TGAGAAGATCATCCAGCAGGCTAAAGCTAAAAAGGAAGAGTAA

Upstream 100 bases:

>100_bases
AAATATTTCGCCGAAAAAAGAGGATTTTTTCAAAGGGAAGGCAAATATATTCCTTATTAAGTTTTTGTTAACCGATGAAG
GATGAGGAGGGCTAATTTTA

Downstream 100 bases:

>100_bases
CGAAGAAGTCTACCAGTACCATTGCCCCCTCTACGGAGGGGGCTTTACTCAATAAGCTCAAAGTGTAGGCGACAGTATCG
GTATGAATTGGCCAATGCTA

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKVYPSTSIRNVAIVAHGGAGKTSLTEALLYNAGATKRLGRVDEGNTVTDYLPEEIKRKVTTNSALAVAEWQDNKINLLD
TPGYSDFFGEVVGALRVVDSLLVVVSAVAGVEVQTEVVWETADNHHLPRITYVNKMDRENANFQKAVESMRERLSGHIVP
VQLPIGEAENFTGIIDILNQKAYTYDNGSEKEIPVPAEYADEVASLREALIEAAAEGDDELLMKYLDGKELSSEEIRSGL
KKAVAEGKAIPVLCGSAWKNMAVKPVLDYIINYLPSPVEATGKDAAALEGENLAALVFKTIADPYVGKLSMFRVYSGVLK
SDSTVYNVNRESEEKIGQLFSLQGKNQLPVTEMKPGDIGAIAKLQVTTTGDTLTTKANPVRLKGIDFPEPTLPVAIKPKS
KGDEDKLSNALARLLEEDPTLRLNKNTETRETILTGMGESHLDITLERLQRKFGVEVEMSTPTVPYRETIRAAVNHIEGK
HKKQTGGHGQYGHVFIDMAPLPDKEFEFTETIFGGAVPRQYIPAVEKGIREAMQEGILAGYPVTNIKVNLADGSYHPVDS
SEMAFKVAAGLAFRKAVEQAKPVLLEPIMNVEITVPEQFMGDIMGDLNSRRGRILGMEPQGKNQVIRAQVPLAEMYRYAI
DLKSITQARGHFKMDFAQYEEVPASIAEKIIQQAKAKKEE

Sequences:

>Translated_680_residues
MKVYPSTSIRNVAIVAHGGAGKTSLTEALLYNAGATKRLGRVDEGNTVTDYLPEEIKRKVTTNSALAVAEWQDNKINLLD
TPGYSDFFGEVVGALRVVDSLLVVVSAVAGVEVQTEVVWETADNHHLPRITYVNKMDRENANFQKAVESMRERLSGHIVP
VQLPIGEAENFTGIIDILNQKAYTYDNGSEKEIPVPAEYADEVASLREALIEAAAEGDDELLMKYLDGKELSSEEIRSGL
KKAVAEGKAIPVLCGSAWKNMAVKPVLDYIINYLPSPVEATGKDAAALEGENLAALVFKTIADPYVGKLSMFRVYSGVLK
SDSTVYNVNRESEEKIGQLFSLQGKNQLPVTEMKPGDIGAIAKLQVTTTGDTLTTKANPVRLKGIDFPEPTLPVAIKPKS
KGDEDKLSNALARLLEEDPTLRLNKNTETRETILTGMGESHLDITLERLQRKFGVEVEMSTPTVPYRETIRAAVNHIEGK
HKKQTGGHGQYGHVFIDMAPLPDKEFEFTETIFGGAVPRQYIPAVEKGIREAMQEGILAGYPVTNIKVNLADGSYHPVDS
SEMAFKVAAGLAFRKAVEQAKPVLLEPIMNVEITVPEQFMGDIMGDLNSRRGRILGMEPQGKNQVIRAQVPLAEMYRYAI
DLKSITQARGHFKMDFAQYEEVPASIAEKIIQQAKAKKEE
>Mature_680_residues
MKVYPSTSIRNVAIVAHGGAGKTSLTEALLYNAGATKRLGRVDEGNTVTDYLPEEIKRKVTTNSALAVAEWQDNKINLLD
TPGYSDFFGEVVGALRVVDSLLVVVSAVAGVEVQTEVVWETADNHHLPRITYVNKMDRENANFQKAVESMRERLSGHIVP
VQLPIGEAENFTGIIDILNQKAYTYDNGSEKEIPVPAEYADEVASLREALIEAAAEGDDELLMKYLDGKELSSEEIRSGL
KKAVAEGKAIPVLCGSAWKNMAVKPVLDYIINYLPSPVEATGKDAAALEGENLAALVFKTIADPYVGKLSMFRVYSGVLK
SDSTVYNVNRESEEKIGQLFSLQGKNQLPVTEMKPGDIGAIAKLQVTTTGDTLTTKANPVRLKGIDFPEPTLPVAIKPKS
KGDEDKLSNALARLLEEDPTLRLNKNTETRETILTGMGESHLDITLERLQRKFGVEVEMSTPTVPYRETIRAAVNHIEGK
HKKQTGGHGQYGHVFIDMAPLPDKEFEFTETIFGGAVPRQYIPAVEKGIREAMQEGILAGYPVTNIKVNLADGSYHPVDS
SEMAFKVAAGLAFRKAVEQAKPVLLEPIMNVEITVPEQFMGDIMGDLNSRRGRILGMEPQGKNQVIRAQVPLAEMYRYAI
DLKSITQARGHFKMDFAQYEEVPASIAEKIIQQAKAKKEE

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=701, Percent_Identity=34.8074179743224, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI19923640, Length=701, Percent_Identity=33.6661911554922, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI25306287, Length=701, Percent_Identity=31.811697574893, Blast_Score=340, Evalue=3e-93,
Organism=Homo sapiens, GI25306283, Length=435, Percent_Identity=35.8620689655172, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI4503483, Length=818, Percent_Identity=25.3056234718826, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94966754, Length=138, Percent_Identity=32.6086956521739, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI157426893, Length=158, Percent_Identity=33.5443037974684, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1789738, Length=698, Percent_Identity=43.2664756446991, Blast_Score=601, Evalue=1e-173,
Organism=Escherichia coli, GI1790835, Length=457, Percent_Identity=26.2582056892779, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI48994988, Length=133, Percent_Identity=38.3458646616541, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788922, Length=210, Percent_Identity=27.1428571428571, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17533571, Length=684, Percent_Identity=33.9181286549708, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17556745, Length=704, Percent_Identity=27.9829545454545, Blast_Score=265, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI17506493, Length=808, Percent_Identity=25.2475247524752, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17557151, Length=147, Percent_Identity=35.3741496598639, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71988819, Length=136, Percent_Identity=33.8235294117647, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988811, Length=136, Percent_Identity=33.8235294117647, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323098, Length=697, Percent_Identity=34.8637015781922, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322359, Length=796, Percent_Identity=30.9045226130653, Blast_Score=349, Evalue=8e-97,
Organism=Saccharomyces cerevisiae, GI6324707, Length=511, Percent_Identity=24.853228962818, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320593, Length=511, Percent_Identity=24.853228962818, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24582462, Length=693, Percent_Identity=34.9206349206349, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI221458488, Length=718, Percent_Identity=31.3370473537604, Blast_Score=301, Evalue=9e-82,
Organism=Drosophila melanogaster, GI24585711, Length=830, Percent_Identity=25.0602409638554, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24585713, Length=830, Percent_Identity=25.0602409638554, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24585709, Length=830, Percent_Identity=25.0602409638554, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI78706572, Length=255, Percent_Identity=29.0196078431373, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 74656; Mature: 74656

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYPSTSIRNVAIVAHGGAGKTSLTEALLYNAGATKRLGRVDEGNTVTDYLPEEIKRKV
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHCCCCCCCCCHHHHCHHHHHHHH
TTNSALAVAEWQDNKINLLDTPGYSDFFGEVVGALRVVDSLLVVVSAVAGVEVQTEVVWE
CCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
TADNHHLPRITYVNKMDRENANFQKAVESMRERLSGHIVPVQLPIGEAENFTGIIDILNQ
CCCCCCCCEEEECCHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCC
KAYTYDNGSEKEIPVPAEYADEVASLREALIEAAAEGDDELLMKYLDGKELSSEEIRSGL
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHH
KKAVAEGKAIPVLCGSAWKNMAVKPVLDYIINYLPSPVEATGKDAAALEGENLAALVFKT
HHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHH
IADPYVGKLSMFRVYSGVLKSDSTVYNVNRESEEKIGQLFSLQGKNQLPVTEMKPGDIGA
HCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
IAKLQVTTTGDTLTTKANPVRLKGIDFPEPTLPVAIKPKSKGDEDKLSNALARLLEEDPT
EEEEEEEECCCEEEECCCCEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
LRLNKNTETRETILTGMGESHLDITLERLQRKFGVEVEMSTPTVPYRETIRAAVNHIEGK
EEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCC
HKKQTGGHGQYGHVFIDMAPLPDKEFEFTETIFGGAVPRQYIPAVEKGIREAMQEGILAG
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEC
YPVTNIKVNLADGSYHPVDSSEMAFKVAAGLAFRKAVEQAKPVLLEPIMNVEITVPEQFM
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCHHHH
GDIMGDLNSRRGRILGMEPQGKNQVIRAQVPLAEMYRYAIDLKSITQARGHFKMDFAQYE
HHHHHHCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECHHHHH
EVPASIAEKIIQQAKAKKEE
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVYPSTSIRNVAIVAHGGAGKTSLTEALLYNAGATKRLGRVDEGNTVTDYLPEEIKRKV
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHCCCCCCCCCHHHHCHHHHHHHH
TTNSALAVAEWQDNKINLLDTPGYSDFFGEVVGALRVVDSLLVVVSAVAGVEVQTEVVWE
CCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
TADNHHLPRITYVNKMDRENANFQKAVESMRERLSGHIVPVQLPIGEAENFTGIIDILNQ
CCCCCCCCEEEECCHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCC
KAYTYDNGSEKEIPVPAEYADEVASLREALIEAAAEGDDELLMKYLDGKELSSEEIRSGL
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHH
KKAVAEGKAIPVLCGSAWKNMAVKPVLDYIINYLPSPVEATGKDAAALEGENLAALVFKT
HHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHH
IADPYVGKLSMFRVYSGVLKSDSTVYNVNRESEEKIGQLFSLQGKNQLPVTEMKPGDIGA
HCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
IAKLQVTTTGDTLTTKANPVRLKGIDFPEPTLPVAIKPKSKGDEDKLSNALARLLEEDPT
EEEEEEEECCCEEEECCCCEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
LRLNKNTETRETILTGMGESHLDITLERLQRKFGVEVEMSTPTVPYRETIRAAVNHIEGK
EEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCC
HKKQTGGHGQYGHVFIDMAPLPDKEFEFTETIFGGAVPRQYIPAVEKGIREAMQEGILAG
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEC
YPVTNIKVNLADGSYHPVDSSEMAFKVAAGLAFRKAVEQAKPVLLEPIMNVEITVPEQFM
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCHHHH
GDIMGDLNSRRGRILGMEPQGKNQVIRAQVPLAEMYRYAIDLKSITQARGHFKMDFAQYE
HHHHHHCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECHHHHH
EVPASIAEKIIQQAKAKKEE
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA