Click here to switch to the map view.

The map label for this gene is gltA [H]

Identifier: 83589970

GI number: 83589970

Start: 1149813

End: 1151159

Strand: Reverse

Name: gltA [H]

Synonym: Moth_1122

Alternate gene names: 83589970

Gene position: 1151159-1149813 (Counterclockwise)

Preceding gene: 83589972

Following gene: 83589969

Centisome position: 43.79

GC content: 46.77

Gene sequence:

>1347_bases
ATGGATCTCCAGGCCTGTCTTGATTATTACTGCCAGCTGGCGGAAAAAAATAATACGATTGATCCGGATTTATATGAAAA
ATATAACGTCAAGCGCGGGCTAAGAAATAAAGACGGCACCGGTGTCCTAGTCGGTTTAACAGAGATCGGGGAAGTCCATG
GCTATATCCTTGATGAAGGGGAAAGAACCCCCGATCACGGTCGCTTGCTCTACCGGGGAATTGATATCTGGGATATTGTA
AGGGGCTTTCAGCAAGAAGGGCGCTTCGGTTTTGAGGAAGTCTGTTACCTGTTACTCTTTGGGGAATTGCCTGACAAGAA
AAGGCTGGAGGAATTCACTCATCTCCTTGCTGAACACAGGTCCCTTCCCGATGGTTTTGTAGAAGACATGATTCTTAAGG
CCCCCAGTAACGATATTATGAATAAATTAGCCCGTAGTGTCCTGGCGGCTTACTCCTACGACCCCAATCCAGATGATATA
AGCATCCGCAATGTTCTCAGGCAATGCATCGAGCTTATCGCCCGGTTTCCCATTATGGTAGCCTATGGGTATCAGGCGAA
GGCTCACTACTATGAGAATAAAAGTCTCTATATCCATCTGCCCCAGACAGAGCTAAGTACGGCCGAGAACTTCCTGTACA
TGATCCGTCCAGACAACCAGTACACATCCCTCGAAGCAGAGTTGCTGGACCTGGCCCTGGTGCTCCACGCCGAGCATGGC
GGCGGTAATAACTCGGCCTTCACCGTCCACGTTGTATCTTCAACAGGCACTGATACTTATTCCGTAATAGCCGCCGCAAC
CGGGTCTTTAAAAGGGCCCAAGCACGGCGGGGCCAATATTAAGGTCATGAAAATGATCGAAGATATAAAGAACAACGTTA
AGGACTGGCATGACGAGGAAGAATTAAGGAATTACCTTATTAAAATCTTACGCAAGGAGGCCTTTGACCGGAGCGGCTTA
ATCTATGGTATCGGCCATGCCGTTTATACTCTTTCAGATCCCAGGGCTGTTTTATTAAAACAAAAGGCAGCCGAACTTGC
CCGGGAAAAGGACATGGAAGATGAATTTGGCCTTTACCTGGCTATAGAAAAAATGGCACCGGAACTCTTTGTTGCCGAAA
AGAAGGTCGATAAGGTGGTCGCTCCTAATGTTGACTTTTATTCCGGTTTTGTTTATAAAATGTTAAATATTCCCATAGAG
TTATATACTCCCATTTTTGCCATATCCAGAATAGCCGGCTGGTGCGCCCACCGGATTGAAGAGCTGGTAAGTGGCGGTAA
AATCTTCAGGCCGGCTTATAAAAATGTCCTTGGCAAGAAGAGTTATATACCCCTGGAACAGAGGTAG

Upstream 100 bases:

>100_bases
GAACTTCACCGTATCCGGGGCAACCAGATAATCATCGACCCCGAACGGGGACCGGAAAATAAATAAAAAAAGTTCATAGG
GAGAGGTGTTGACCTTAAAG

Downstream 100 bases:

>100_bases
AACAAAAACCCGTTTTACGGATAAAGGTAGTAGAAAATAGATAAGGGAGAAGGCAAAATATTGGGCTTAGAAATCTGCGG
GAGCGAACACGGTTCGTCTG

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDLQACLDYYCQLAEKNNTIDPDLYEKYNVKRGLRNKDGTGVLVGLTEIGEVHGYILDEGERTPDHGRLLYRGIDIWDIV
RGFQQEGRFGFEEVCYLLLFGELPDKKRLEEFTHLLAEHRSLPDGFVEDMILKAPSNDIMNKLARSVLAAYSYDPNPDDI
SIRNVLRQCIELIARFPIMVAYGYQAKAHYYENKSLYIHLPQTELSTAENFLYMIRPDNQYTSLEAELLDLALVLHAEHG
GGNNSAFTVHVVSSTGTDTYSVIAAATGSLKGPKHGGANIKVMKMIEDIKNNVKDWHDEEELRNYLIKILRKEAFDRSGL
IYGIGHAVYTLSDPRAVLLKQKAAELAREKDMEDEFGLYLAIEKMAPELFVAEKKVDKVVAPNVDFYSGFVYKMLNIPIE
LYTPIFAISRIAGWCAHRIEELVSGGKIFRPAYKNVLGKKSYIPLEQR

Sequences:

>Translated_448_residues
MDLQACLDYYCQLAEKNNTIDPDLYEKYNVKRGLRNKDGTGVLVGLTEIGEVHGYILDEGERTPDHGRLLYRGIDIWDIV
RGFQQEGRFGFEEVCYLLLFGELPDKKRLEEFTHLLAEHRSLPDGFVEDMILKAPSNDIMNKLARSVLAAYSYDPNPDDI
SIRNVLRQCIELIARFPIMVAYGYQAKAHYYENKSLYIHLPQTELSTAENFLYMIRPDNQYTSLEAELLDLALVLHAEHG
GGNNSAFTVHVVSSTGTDTYSVIAAATGSLKGPKHGGANIKVMKMIEDIKNNVKDWHDEEELRNYLIKILRKEAFDRSGL
IYGIGHAVYTLSDPRAVLLKQKAAELAREKDMEDEFGLYLAIEKMAPELFVAEKKVDKVVAPNVDFYSGFVYKMLNIPIE
LYTPIFAISRIAGWCAHRIEELVSGGKIFRPAYKNVLGKKSYIPLEQR
>Mature_448_residues
MDLQACLDYYCQLAEKNNTIDPDLYEKYNVKRGLRNKDGTGVLVGLTEIGEVHGYILDEGERTPDHGRLLYRGIDIWDIV
RGFQQEGRFGFEEVCYLLLFGELPDKKRLEEFTHLLAEHRSLPDGFVEDMILKAPSNDIMNKLARSVLAAYSYDPNPDDI
SIRNVLRQCIELIARFPIMVAYGYQAKAHYYENKSLYIHLPQTELSTAENFLYMIRPDNQYTSLEAELLDLALVLHAEHG
GGNNSAFTVHVVSSTGTDTYSVIAAATGSLKGPKHGGANIKVMKMIEDIKNNVKDWHDEEELRNYLIKILRKEAFDRSGL
IYGIGHAVYTLSDPRAVLLKQKAAELAREKDMEDEFGLYLAIEKMAPELFVAEKKVDKVVAPNVDFYSGFVYKMLNIPIE
LYTPIFAISRIAGWCAHRIEELVSGGKIFRPAYKNVLGKKSYIPLEQR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=364, Percent_Identity=28.2967032967033, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1786939, Length=378, Percent_Identity=32.5396825396825, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786527, Length=382, Percent_Identity=29.0575916230367, Blast_Score=146, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17555174, Length=352, Percent_Identity=27.5568181818182, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319850, Length=394, Percent_Identity=26.3959390862944, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324328, Length=393, Percent_Identity=25.6997455470738, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325257, Length=403, Percent_Identity=25.3101736972705, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640124, Length=352, Percent_Identity=31.25, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24640126, Length=352, Percent_Identity=31.25, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356863, Length=381, Percent_Identity=28.0839895013123, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 50903; Mature: 50903

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLQACLDYYCQLAEKNNTIDPDLYEKYNVKRGLRNKDGTGVLVGLTEIGEVHGYILDEG
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCCEEECCC
ERTPDHGRLLYRGIDIWDIVRGFQQEGRFGFEEVCYLLLFGELPDKKRLEEFTHLLAEHR
CCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
SLPDGFVEDMILKAPSNDIMNKLARSVLAAYSYDPNPDDISIRNVLRQCIELIARFPIMV
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
AYGYQAKAHYYENKSLYIHLPQTELSTAENFLYMIRPDNQYTSLEAELLDLALVLHAEHG
EECCCCEEEEEECCEEEEEECCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHEEECCC
GGNNSAFTVHVVSSTGTDTYSVIAAATGSLKGPKHGGANIKVMKMIEDIKNNVKDWHDEE
CCCCCEEEEEEEECCCCCHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
ELRNYLIKILRKEAFDRSGLIYGIGHAVYTLSDPRAVLLKQKAAELAREKDMEDEFGLYL
HHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEE
AIEKMAPELFVAEKKVDKVVAPNVDFYSGFVYKMLNIPIELYTPIFAISRIAGWCAHRIE
EEHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ELVSGGKIFRPAYKNVLGKKSYIPLEQR
HHHCCCCEECHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDLQACLDYYCQLAEKNNTIDPDLYEKYNVKRGLRNKDGTGVLVGLTEIGEVHGYILDEG
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCCEEECCC
ERTPDHGRLLYRGIDIWDIVRGFQQEGRFGFEEVCYLLLFGELPDKKRLEEFTHLLAEHR
CCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
SLPDGFVEDMILKAPSNDIMNKLARSVLAAYSYDPNPDDISIRNVLRQCIELIARFPIMV
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
AYGYQAKAHYYENKSLYIHLPQTELSTAENFLYMIRPDNQYTSLEAELLDLALVLHAEHG
EECCCCEEEEEECCEEEEEECCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHEEECCC
GGNNSAFTVHVVSSTGTDTYSVIAAATGSLKGPKHGGANIKVMKMIEDIKNNVKDWHDEE
CCCCCEEEEEEEECCCCCHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
ELRNYLIKILRKEAFDRSGLIYGIGHAVYTLSDPRAVLLKQKAAELAREKDMEDEFGLYL
HHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEE
AIEKMAPELFVAEKKVDKVVAPNVDFYSGFVYKMLNIPIELYTPIFAISRIAGWCAHRIE
EEHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ELVSGGKIFRPAYKNVLGKKSYIPLEQR
HHHCCCCEECHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]