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The map label for this gene is hgdC [H]

Identifier: 83589854

GI number: 83589854

Start: 1033601

End: 1034368

Strand: Reverse

Name: hgdC [H]

Synonym: Moth_1005

Alternate gene names: 83589854

Gene position: 1034368-1033601 (Counterclockwise)

Preceding gene: 83589855

Following gene: 83589853

Centisome position: 39.35

GC content: 62.24

Gene sequence:

>768_bases
TTGAGTCTAACTGCGGGAGTAGATATCGGCTCCTTGACCACCAAAGCAGTAATAGTCCGGGACGGCCGGATGGTGGGAGC
CGCCGTCCTTAAGAGTGGCGTTAACAGCGTCGAGATCGCCGAAAAGGCTTTACAGGAAGCCCTGGAACAGGCCGGAGCAG
GCGCAGAGTCCCTGGACGGCATTGTCGCCACAGGCTATGGCCGTATCCGGGTGCCCTTCGCCCAGCGCCGGGTCACCGAA
ATAACCTGCCACGCCCGGGGAATTTATCACCTCTGGCCGGAAGTACGCACGGTCATCGATATCGGCGGCCAGGACAGCAA
AGTCATCCTCCTGGATGCCGGGGGCAAGGTACGGGATTTTGTCATGAACGAGAAGTGTGCCGCCGGTACCGGCCGTTTCC
TGGAAGTCATGGCCGGTGCCCTGGATGTCCCGGTGGAGGAAATGGGGGCCATCTCCCAGCAGGCAGGCCAGGGCGCCAGC
ATTAGCAGCATGTGCACCGTCTTTGCCGAATCCGAAGTTGTTTCCCTGGTGGCCGAAGGGCGTCCGGTGGCAGAAATAAT
CAGGGGCCTGCATAATGCCGTCGCCCAGCGGGTAGTGGCCATGGCCCAACGGGTAGGCTGGGAAGAGCCGGTGGCCATGA
CGGGCGGGGTGGCCAAAAACCCGGGAGTGGTAAAAAGCCTGGAAGAAACCCTGGGCACCAGCATCCGCGTACCCCCGGAC
CCGCAAATAATAGGGGCTCTGGGGGCGGCCCTGCTGGCGATCGGGTAG

Upstream 100 bases:

>100_bases
ATTGTGTCGATCAAAGTAAGTACGCCCCCGGCGCTACCAGAACGCGCCTGGAAGGTTTCCTGGAAATGCTATTATAAAAA
ACACCGGGAGGTTATGCCCT

Downstream 100 bases:

>100_bases
GAAAGCCAAGGGAACTGCGCCTCCAGCTCAAACCAGGACCGCAAAAGTTACTCAACCACCACCTCCTTTATTGCGTAGCG
AATAGTTTCGTTTACTTGTA

Product: CoA enzyme activase

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSLTAGVDIGSLTTKAVIVRDGRMVGAAVLKSGVNSVEIAEKALQEALEQAGAGAESLDGIVATGYGRIRVPFAQRRVTE
ITCHARGIYHLWPEVRTVIDIGGQDSKVILLDAGGKVRDFVMNEKCAAGTGRFLEVMAGALDVPVEEMGAISQQAGQGAS
ISSMCTVFAESEVVSLVAEGRPVAEIIRGLHNAVAQRVVAMAQRVGWEEPVAMTGGVAKNPGVVKSLEETLGTSIRVPPD
PQIIGALGAALLAIG

Sequences:

>Translated_255_residues
MSLTAGVDIGSLTTKAVIVRDGRMVGAAVLKSGVNSVEIAEKALQEALEQAGAGAESLDGIVATGYGRIRVPFAQRRVTE
ITCHARGIYHLWPEVRTVIDIGGQDSKVILLDAGGKVRDFVMNEKCAAGTGRFLEVMAGALDVPVEEMGAISQQAGQGAS
ISSMCTVFAESEVVSLVAEGRPVAEIIRGLHNAVAQRVVAMAQRVGWEEPVAMTGGVAKNPGVVKSLEETLGTSIRVPPD
PQIIGALGAALLAIG
>Mature_254_residues
SLTAGVDIGSLTTKAVIVRDGRMVGAAVLKSGVNSVEIAEKALQEALEQAGAGAESLDGIVATGYGRIRVPFAQRRVTEI
TCHARGIYHLWPEVRTVIDIGGQDSKVILLDAGGKVRDFVMNEKCAAGTGRFLEVMAGALDVPVEEMGAISQQAGQGASI
SSMCTVFAESEVVSLVAEGRPVAEIIRGLHNAVAQRVVAMAQRVGWEEPVAMTGGVAKNPGVVKSLEETLGTSIRVPPDP
QIIGALGAALLAIG

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=252, Percent_Identity=42.4603174603175, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 26409; Mature: 26278

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTAGVDIGSLTTKAVIVRDGRMVGAAVLKSGVNSVEIAEKALQEALEQAGAGAESLDG
CCCCCCCCCCCHHEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCC
IVATGYGRIRVPFAQRRVTEITCHARGIYHLWPEVRTVIDIGGQDSKVILLDAGGKVRDF
EEEECCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
VMNEKCAAGTGRFLEVMAGALDVPVEEMGAISQQAGQGASISSMCTVFAESEVVSLVAEG
HHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
RPVAEIIRGLHNAVAQRVVAMAQRVGWEEPVAMTGGVAKNPGVVKSLEETLGTSIRVPPD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCC
PQIIGALGAALLAIG
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLTAGVDIGSLTTKAVIVRDGRMVGAAVLKSGVNSVEIAEKALQEALEQAGAGAESLDG
CCCCCCCCCCHHEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCC
IVATGYGRIRVPFAQRRVTEITCHARGIYHLWPEVRTVIDIGGQDSKVILLDAGGKVRDF
EEEECCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
VMNEKCAAGTGRFLEVMAGALDVPVEEMGAISQQAGQGASISSMCTVFAESEVVSLVAEG
HHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
RPVAEIIRGLHNAVAQRVVAMAQRVGWEEPVAMTGGVAKNPGVVKSLEETLGTSIRVPPD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCC
PQIIGALGAALLAIG
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]