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The map label for this gene is mcpB [H]

Identifier: 83589366

GI number: 83589366

Start: 519708

End: 521234

Strand: Reverse

Name: mcpB [H]

Synonym: Moth_0502

Alternate gene names: 83589366

Gene position: 521234-519708 (Counterclockwise)

Preceding gene: 83589369

Following gene: 83589365

Centisome position: 19.83

GC content: 51.6

Gene sequence:

>1527_bases
ATGATTTCTTTTGCTTTATGGGGAACCGCCCTAACGGGATGGGTTGTGGCTGTGGTTCTCTGGAAGAGATATAGCAATGC
CCAGGCAGATTTAAAGGAATTCCTCGACAGCCTGGGTCAGGGCGATATAGTCCGAGCGGAAGGATTCTTTCGAACCCATA
GTTTTTCTATGGCTCTGGGGGAAAGTACGCGCATGGTTCTCGAAAGATTCTTTGAAATCATTGCTTTCATTCAGAAAGTC
GCCGACGAACTAAATTATACAGCTTCATTATTCGTACAAGAAACCGTAGCTGGCAATACCAGCTTCCGGGAAATGGCCGC
CGCCTTGCAGGATATTGCCGGGGGCGCTGACGAGCAGGCGCATGCCTCCCAAAAAACAGCCGAAAATGTTGGTCAGTTCA
CCAATTTAGCCGAAGAAATCGCCAGCCGTTCCCAAATGAGTTTTACCCTGGGTAAAGAGGCACTATCCAAGGTACAAGCG
GGCAGGGAATTACTAGAAAAACTGATCGACGAAATGAAAAATGTAGCCTCTTTTAATACCGAAGCGGCCACAGAGATGGA
AGACCTGGAAGGAAAAATAGCACGGATCAATGAATTTGTGCACACAATCGATCACCTAGCGGGCCAGACCAATCTCCTTT
CCCTTAACGCTGCCATTGAAGCAGCCCGGGCCGGAGAACAGGGCCGCGGCTTCGCGGTGGTGGCCGAAGAAGTGAGAAAA
CTGGCTGAAGAATCAGCGGGGGCGGCCCGTCATATAACCGAACTGGCAGAAGAGATTCAGGCCCGGGCCGGCAGGGCTGC
TCTCCAGGTAAAAAACAGCGCTGAACTGGTAAATAATAACGCCCTTCGCAGCAAGGAGGTAGAAACAGCTTTTGAAGCCA
TCGGCCGCGCCGTCAACCAAGCAGCAAAGGCGAGCGAAGAAATAACCAGGTATACTGAACAACAATTGACCCACGTCAAG
ATGGCCAACGACAACGCTGCTCGCATGGCCGCCGTTGCTGAACAAACGGCAGCCAGCATAGAGCAGATTTATGCCTCCAG
TTCTGAACAACAAAACGCAATGGCCAGGATAGAGAAGAATGCCCGGGAAATATCGCAGATGGCCGACAATTTCTTTAAAC
TGGCCTCCGAATATACCAGAAACTGCTGGGATGAAAACCTGTGCCAAAAATTGGTACGGGATGGGCTTGATAATCTCCGC
CGGCTGGCCTCCACGCCGGAGGTTCAATCCATGGAAGTTGATAAAATAAAACCCCTTTTAGATGAAGCAGCAGCTACAAT
GCCAATCGTGAAGACCATCCGGGCTGTAGACCCGGACGGAAATACCGTCTATAGTCAACCGCCGGGCAAAGTAACCAATT
GGTCCTTCCGCCCATGGTTCCAGGCGGCGAAAAGAGGGCAAGAATATCATACTCAACCTTTCATTACCCAGGGAACCGGC
CGCCTGGCAATCACTGTTGCCGTACCGGTGCATGGGGGAGACGCCGGGATTGTAGGTGTACTGGCCGCCAACATTGCCCC
GGCCTGA

Upstream 100 bases:

>100_bases
TGAAGGTTTTAAATTTAAACCATATCAGCCGGCAGGACATGCTGCCAATTAAGCGAATTTAATGATAAAGGCTCTAGTAA
AAGTGGGGGAATAAAAGAAA

Downstream 100 bases:

>100_bases
AATACCTTCGTCTCCTCCCGGGCGGATCACAAAAAGGCTTTTAGACTAATGTTTGCCCCCCAATTTCCCATACTCCACAG
GCAGCCCGAAAACCATCATT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MISFALWGTALTGWVVAVVLWKRYSNAQADLKEFLDSLGQGDIVRAEGFFRTHSFSMALGESTRMVLERFFEIIAFIQKV
ADELNYTASLFVQETVAGNTSFREMAAALQDIAGGADEQAHASQKTAENVGQFTNLAEEIASRSQMSFTLGKEALSKVQA
GRELLEKLIDEMKNVASFNTEAATEMEDLEGKIARINEFVHTIDHLAGQTNLLSLNAAIEAARAGEQGRGFAVVAEEVRK
LAEESAGAARHITELAEEIQARAGRAALQVKNSAELVNNNALRSKEVETAFEAIGRAVNQAAKASEEITRYTEQQLTHVK
MANDNAARMAAVAEQTAASIEQIYASSSEQQNAMARIEKNAREISQMADNFFKLASEYTRNCWDENLCQKLVRDGLDNLR
RLASTPEVQSMEVDKIKPLLDEAAATMPIVKTIRAVDPDGNTVYSQPPGKVTNWSFRPWFQAAKRGQEYHTQPFITQGTG
RLAITVAVPVHGGDAGIVGVLAANIAPA

Sequences:

>Translated_508_residues
MISFALWGTALTGWVVAVVLWKRYSNAQADLKEFLDSLGQGDIVRAEGFFRTHSFSMALGESTRMVLERFFEIIAFIQKV
ADELNYTASLFVQETVAGNTSFREMAAALQDIAGGADEQAHASQKTAENVGQFTNLAEEIASRSQMSFTLGKEALSKVQA
GRELLEKLIDEMKNVASFNTEAATEMEDLEGKIARINEFVHTIDHLAGQTNLLSLNAAIEAARAGEQGRGFAVVAEEVRK
LAEESAGAARHITELAEEIQARAGRAALQVKNSAELVNNNALRSKEVETAFEAIGRAVNQAAKASEEITRYTEQQLTHVK
MANDNAARMAAVAEQTAASIEQIYASSSEQQNAMARIEKNAREISQMADNFFKLASEYTRNCWDENLCQKLVRDGLDNLR
RLASTPEVQSMEVDKIKPLLDEAAATMPIVKTIRAVDPDGNTVYSQPPGKVTNWSFRPWFQAAKRGQEYHTQPFITQGTG
RLAITVAVPVHGGDAGIVGVLAANIAPA
>Mature_508_residues
MISFALWGTALTGWVVAVVLWKRYSNAQADLKEFLDSLGQGDIVRAEGFFRTHSFSMALGESTRMVLERFFEIIAFIQKV
ADELNYTASLFVQETVAGNTSFREMAAALQDIAGGADEQAHASQKTAENVGQFTNLAEEIASRSQMSFTLGKEALSKVQA
GRELLEKLIDEMKNVASFNTEAATEMEDLEGKIARINEFVHTIDHLAGQTNLLSLNAAIEAARAGEQGRGFAVVAEEVRK
LAEESAGAARHITELAEEIQARAGRAALQVKNSAELVNNNALRSKEVETAFEAIGRAVNQAAKASEEITRYTEQQLTHVK
MANDNAARMAAVAEQTAASIEQIYASSSEQQNAMARIEKNAREISQMADNFFKLASEYTRNCWDENLCQKLVRDGLDNLR
RLASTPEVQSMEVDKIKPLLDEAAATMPIVKTIRAVDPDGNTVYSQPPGKVTNWSFRPWFQAAKRGQEYHTQPFITQGTG
RLAITVAVPVHGGDAGIVGVLAANIAPA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=224, Percent_Identity=36.1607142857143, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788194, Length=344, Percent_Identity=29.0697674418605, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI2367378, Length=218, Percent_Identity=31.651376146789, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787690, Length=257, Percent_Identity=30.7392996108949, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=236, Percent_Identity=33.0508474576271, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55447; Mature: 55447

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFALWGTALTGWVVAVVLWKRYSNAQADLKEFLDSLGQGDIVRAEGFFRTHSFSMALG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHC
ESTRMVLERFFEIIAFIQKVADELNYTASLFVQETVAGNTSFREMAAALQDIAGGADEQA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHH
HASQKTAENVGQFTNLAEEIASRSQMSFTLGKEALSKVQAGRELLEKLIDEMKNVASFNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EAATEMEDLEGKIARINEFVHTIDHLAGQTNLLSLNAAIEAARAGEQGRGFAVVAEEVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHH
LAEESAGAARHITELAEEIQARAGRAALQVKNSAELVNNNALRSKEVETAFEAIGRAVNQ
HHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AAKASEEITRYTEQQLTHVKMANDNAARMAAVAEQTAASIEQIYASSSEQQNAMARIEKN
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AREISQMADNFFKLASEYTRNCWDENLCQKLVRDGLDNLRRLASTPEVQSMEVDKIKPLL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
DEAAATMPIVKTIRAVDPDGNTVYSQPPGKVTNWSFRPWFQAAKRGQEYHTQPFITQGTG
HHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEECCCC
RLAITVAVPVHGGDAGIVGVLAANIAPA
CEEEEEEEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MISFALWGTALTGWVVAVVLWKRYSNAQADLKEFLDSLGQGDIVRAEGFFRTHSFSMALG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHC
ESTRMVLERFFEIIAFIQKVADELNYTASLFVQETVAGNTSFREMAAALQDIAGGADEQA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHH
HASQKTAENVGQFTNLAEEIASRSQMSFTLGKEALSKVQAGRELLEKLIDEMKNVASFNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EAATEMEDLEGKIARINEFVHTIDHLAGQTNLLSLNAAIEAARAGEQGRGFAVVAEEVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHH
LAEESAGAARHITELAEEIQARAGRAALQVKNSAELVNNNALRSKEVETAFEAIGRAVNQ
HHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AAKASEEITRYTEQQLTHVKMANDNAARMAAVAEQTAASIEQIYASSSEQQNAMARIEKN
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AREISQMADNFFKLASEYTRNCWDENLCQKLVRDGLDNLRRLASTPEVQSMEVDKIKPLL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
DEAAATMPIVKTIRAVDPDGNTVYSQPPGKVTNWSFRPWFQAAKRGQEYHTQPFITQGTG
HHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEECCCC
RLAITVAVPVHGGDAGIVGVLAANIAPA
CEEEEEEEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]