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The map label for this gene is folB [H]

Identifier: 83589275

GI number: 83589275

Start: 412557

End: 412925

Strand: Reverse

Name: folB [H]

Synonym: Moth_0407

Alternate gene names: 83589275

Gene position: 412925-412557 (Counterclockwise)

Preceding gene: 83589276

Following gene: 83589272

Centisome position: 15.71

GC content: 60.16

Gene sequence:

>369_bases
TTGGGTCAGGATAAGATTATTTTAGCCGGGCTGGAGTTTTATGGCTTCCACGGCAACCATCCGGCAGAGCAGCAGTTGGG
GCAGCCCTTTATTGTCGACCTCGAACTCTACCTGGACCTGGAACCTGCCGGGAGGACCGATGCTCTGGAAGCCACCGTCA
ACTACGGCCAGGTCTACCGCCTGGTGCAGGAAATAGTCACCGGCCGCCCCTATAAACTCCTGGAGGCCCTGGCCGCGGCC
ATCAGCGACGGCATTCTGGCCGGTTTCCCGGTGGACGAGGTCCTGGTGCGTGTAAAAAAACCCCGGGCACCACTGCCCGG
GAGCTTTGACTACGCCGCCGTTGAGATCCGGCGCCGGAGAAAAGAATAG

Upstream 100 bases:

>100_bases
TTACCTCCGCCGTCCGGGGTCTTTTCCGCCGCGACCAGGCCGCCCGGGCGGAAGCTATGTCCCTTATCCAGGGTCGCTAA
GCAGAAAGGGGGTCAACTCT

Downstream 100 bases:

>100_bases
TTTTAGAACAGCAGGGAATATATCTTATCCGTTACCCTGGCGAAGGCTTCGTCCTTCATATTCCGCGGCCGGGGCAGGTC
CACCCTGACATCGGCCAGGA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MGQDKIILAGLEFYGFHGNHPAEQQLGQPFIVDLELYLDLEPAGRTDALEATVNYGQVYRLVQEIVTGRPYKLLEALAAA
ISDGILAGFPVDEVLVRVKKPRAPLPGSFDYAAVEIRRRRKE

Sequences:

>Translated_122_residues
MGQDKIILAGLEFYGFHGNHPAEQQLGQPFIVDLELYLDLEPAGRTDALEATVNYGQVYRLVQEIVTGRPYKLLEALAAA
ISDGILAGFPVDEVLVRVKKPRAPLPGSFDYAAVEIRRRRKE
>Mature_121_residues
GQDKIILAGLEFYGFHGNHPAEQQLGQPFIVDLELYLDLEPAGRTDALEATVNYGQVYRLVQEIVTGRPYKLLEALAAAI
SDGILAGFPVDEVLVRVKKPRAPLPGSFDYAAVEIRRRRKE

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13566; Mature: 13435

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQDKIILAGLEFYGFHGNHPAEQQLGQPFIVDLELYLDLEPAGRTDALEATVNYGQVYR
CCCCCEEEEEEEEECCCCCCCHHHHCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
LVQEIVTGRPYKLLEALAAAISDGILAGFPVDEVLVRVKKPRAPLPGSFDYAAVEIRRRR
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
KE
CC
>Mature Secondary Structure 
GQDKIILAGLEFYGFHGNHPAEQQLGQPFIVDLELYLDLEPAGRTDALEATVNYGQVYR
CCCCEEEEEEEEECCCCCCCHHHHCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
LVQEIVTGRPYKLLEALAAAISDGILAGFPVDEVLVRVKKPRAPLPGSFDYAAVEIRRRR
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]