Click here to switch to the map view.

The map label for this gene is xerC

Identifier: 83313349

GI number: 83313349

Start: 4659354

End: 4660298

Strand: Reverse

Name: xerC

Synonym: amb4250

Alternate gene names: 83313349

Gene position: 4660298-4659354 (Counterclockwise)

Preceding gene: 83313350

Following gene: 83313348

Centisome position: 93.82

GC content: 69.63

Gene sequence:

>945_bases
ATGCCTCCCAGTCCCATCCATTTCGCGGCAAAGGCCGATCTGGCCCGCGCGGTGGAATCGTGGTGGCAGTGGCTGGGATC
CGAGCGGCGGGCCTCGTCCCATACCCTGGACGGCTATGGCCGCGACCTGGCCGCCTTCCTGACCTTCCTGACCGAGCATC
TGGCCGCCGAGCCCGATCTGGCCGCTCTGGCAAGCCTGGGGGCGGGGGATTTCCGCGCCTTCCTGGCGCGCCGCACCCAG
GACGGGTTGGGCCGGTCGTCCCTGGCCCGCCTGATGTCCACCCTGCGCGGCTTCTTCAAGTTTCTCGACCGCCACGATCT
GGTCCACAACCCGGCGCTCAAGGCGGTGAAGTCGCCGCGCCCGCCGAAATCGGTTCCCAAGCCCCTGGCCCCCGACGAGG
CGCTGGAAGCCTTGTCCAGCGCGGGCGAATTGCATGACGAGCCCTGGCTGGCGGCCCGCGACGTGGCGCTGTTCACCCTG
CTTTACGGTGCGGGGCTGCGCCTGGGCGAGGCCCTGTCGCTGACCCGCCGCGACCTGCCCAAGGGCGACACCATGGTCAT
CACCGGCAAGGGCAACAAGCAGCGGGTGGTCCCCGTGCTGCCCGTGGTCCGGGACGCCATCGCCGATTACCTGAAGCGCC
TGCCCTATCCGGCCGAGCCCACCGACCCGATCTTTCTCGGCGCGCGCGGCGGGCCGCTCAATCCCGGCGTGGTGCAGCGG
CAGATGCGCCGCCTCAGACAGATGATGGGCCTGCCCGAGACCGCCACGCCCCATGCGCTGCGGCATTCCTTCGCCACCCA
TCTGCTGGCCGGCGGCGGCGATCTCCGGACCATTCAGGAATTGCTGGGCCATTCCTCGCTGTCCACCACTCAGCGCTATA
CCGAGGTGGATGCGGCGCGTCTCACCCGCGTCTATCGTGACGCCCATCCGAGGGCCAAGGCATGA

Upstream 100 bases:

>100_bases
ATCGCTTCGGCGACGATCCGCTGGCAGGCTCCGCCTAGGCACGCCACCTTGTCGCCCCGGGGCAGGCCTCGGGGCGACTC
TTCCCGGAGCGTTGGTTCCC

Downstream 100 bases:

>100_bases
GTCTGGTCATTTCCTTCGATCTGCCCGTCGAGGCCGACACCATCCGCCTGGGCCGCAAGCTGGCCGCCCTGGTCCGTCCC
GGCGACGTCATCGCCCTGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPPSPIHFAAKADLARAVESWWQWLGSERRASSHTLDGYGRDLAAFLTFLTEHLAAEPDLAALASLGAGDFRAFLARRTQ
DGLGRSSLARLMSTLRGFFKFLDRHDLVHNPALKAVKSPRPPKSVPKPLAPDEALEALSSAGELHDEPWLAARDVALFTL
LYGAGLRLGEALSLTRRDLPKGDTMVITGKGNKQRVVPVLPVVRDAIADYLKRLPYPAEPTDPIFLGARGGPLNPGVVQR
QMRRLRQMMGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHSSLSTTQRYTEVDAARLTRVYRDAHPRAKA

Sequences:

>Translated_314_residues
MPPSPIHFAAKADLARAVESWWQWLGSERRASSHTLDGYGRDLAAFLTFLTEHLAAEPDLAALASLGAGDFRAFLARRTQ
DGLGRSSLARLMSTLRGFFKFLDRHDLVHNPALKAVKSPRPPKSVPKPLAPDEALEALSSAGELHDEPWLAARDVALFTL
LYGAGLRLGEALSLTRRDLPKGDTMVITGKGNKQRVVPVLPVVRDAIADYLKRLPYPAEPTDPIFLGARGGPLNPGVVQR
QMRRLRQMMGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHSSLSTTQRYTEVDAARLTRVYRDAHPRAKA
>Mature_313_residues
PPSPIHFAAKADLARAVESWWQWLGSERRASSHTLDGYGRDLAAFLTFLTEHLAAEPDLAALASLGAGDFRAFLARRTQD
GLGRSSLARLMSTLRGFFKFLDRHDLVHNPALKAVKSPRPPKSVPKPLAPDEALEALSSAGELHDEPWLAARDVALFTLL
YGAGLRLGEALSLTRRDLPKGDTMVITGKGNKQRVVPVLPVVRDAIADYLKRLPYPAEPTDPIFLGARGGPLNPGVVQRQ
MRRLRQMMGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHSSLSTTQRYTEVDAARLTRVYRDAHPRAKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=307, Percent_Identity=39.413680781759, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=35.1791530944625, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1790768, Length=154, Percent_Identity=33.7662337662338, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34401; Mature: 34270

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSPIHFAAKADLARAVESWWQWLGSERRASSHTLDGYGRDLAAFLTFLTEHLAAEPDL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
AALASLGAGDFRAFLARRTQDGLGRSSLARLMSTLRGFFKFLDRHDLVHNPALKAVKSPR
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPKSVPKPLAPDEALEALSSAGELHDEPWLAARDVALFTLLYGAGLRLGEALSLTRRDLP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
KGDTMVITGKGNKQRVVPVLPVVRDAIADYLKRLPYPAEPTDPIFLGARGGPLNPGVVQR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHH
QMRRLRQMMGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHSSLSTTQRYTEVDAAR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LTRVYRDAHPRAKA
HHHHHHHCCCCCCC
>Mature Secondary Structure 
PPSPIHFAAKADLARAVESWWQWLGSERRASSHTLDGYGRDLAAFLTFLTEHLAAEPDL
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
AALASLGAGDFRAFLARRTQDGLGRSSLARLMSTLRGFFKFLDRHDLVHNPALKAVKSPR
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPKSVPKPLAPDEALEALSSAGELHDEPWLAARDVALFTLLYGAGLRLGEALSLTRRDLP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
KGDTMVITGKGNKQRVVPVLPVVRDAIADYLKRLPYPAEPTDPIFLGARGGPLNPGVVQR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHH
QMRRLRQMMGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHSSLSTTQRYTEVDAAR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LTRVYRDAHPRAKA
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]