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The map label for this gene is atpD

Identifier: 83313238

GI number: 83313238

Start: 4544377

End: 4545801

Strand: Reverse

Name: atpD

Synonym: amb4139

Alternate gene names: 83313238

Gene position: 4545801-4544377 (Counterclockwise)

Preceding gene: 83313239

Following gene: 83313237

Centisome position: 91.52

GC content: 65.33

Gene sequence:

>1425_bases
ATGGCAAACAAGAACGTCGGCACGATTACCCAGGTCCTGGGCGCCGTCGTGGACGTGCGCTTCGACGGCCAGCTGCCGGC
CATCCTCAGCGCGCTTCACCTGGAACATCAGGGCAAGAAGCTGGTTCTCGAAGTCGCTCAGCATCTGGGCGAGTCCACCG
TGCGTACCATCGCCATGGACTCCACGGACGGTCTGACCCGTGGCACCGAAGTGGTGGACACCGGCGCCGCCATCCAGATG
CCCGTCGGCCCCGAGACCCTGGGCCGCATCATCAACGTGATCGGCGAGCCCATCGACGAGCGCGGCCCCATCGGCAACAA
GACCACCCTGCCGATCCATGCCGACGCCCCGGAATTCGTCGACCAGTCCACCGAGACCGAGATCCTGGTCACCGGCATCA
AGGTCATCGACCTGCTGGCCCCGTACTGCAAGGGCGGCAAGATCGGCCTGTGCGGCGGCGCCGGCGTGGGCAAGACCGTG
CTGATCATGGAGCTGATCAACAACATCGCCAAGGCGCACGGCGGTTACTCGGTGTTCGCCGGCGTGGGCGAGCGTACCCG
TGAAGGCAACGACCTCTATCACGAGATGATCGAGTCGGGCGTCATCAAGCTGGACGGCCCGGGCTCCAAGGTGGCCCTGG
TGTACGGCCAGATGAACGAGCCCCCGGGCGCCCGTGCCCGCGTCGCCCTGTCGGGCCTGACCGTCGCCGAGTACTTCCGC
GACGTGGAAGGTCAGGACGTGCTGTTCTTCGTGGACAACATCTTCCGCTTCACTCAGGCCGGTTCGGAAGTGTCCGCGCT
GCTGGGCCGCATCCCGTCGGCGGTGGGCTATCAGCCCACTCTCGCCACCGACATGGGCGCCCTGCAGGAGCGCATCACCT
CCACCAAGAAGGGCTCGATCACCTCGGTGCAGGCCATTTACGTGCCGGCCGACGATCTCACCGACCCGGCTCCGGCCACG
TCGTTCGCCCACTTGGACGCCACCACCGTGCTGAATCGTCAGATCGCCGAGCTGGGCATCTACCCGGCCGTGGATCCGCT
CGACTCCACCTCTCGCGTTCTGGATCCCCGCGTGGTCGGCAACGATCACTACCAGACCGCCCGCGACGTGCAGCGCATCC
TGCAGACCTACAAGTCGCTGCAGGACATCATCGCCATCCTGGGCATGGACGAGCTGTCGGAAGAGGACAAGCTGGTCGTG
TCGCGCGCTCGTAAGATCCAGCGCTTCCTGTCCCAGCCCTTCCACGTGGCCGAAATCTTCACCGGTTCGCCGGGCAAGCT
GGTGGCCATCGACGACACCATCAAGGGCTTCAAGGCCATCGTCGCCGGCGAATACGACCACCTCCCCGAGGCTGCCTTCT
ACATGGTTGGCGGCATCGACGAGGTGATCGAGAAGGCCAAGAAGATGGCTGCCGAGGCGGCCTAA

Upstream 100 bases:

>100_bases
CGATCAAGTACAACCGGTCGCGCCAGGCCCAGATCACCAAGGAACTGATCGAAATCATCTCCGGCGCCGAAGCGCTGTGA
CGGAAGACTAGGAGCACACC

Downstream 100 bases:

>100_bases
GGCTTTCGGGAATAATTAGGGGCGGGTTCCTTCGGGGACCCGCCGCTAAAAAAGTTGAAGGACTCGCGGCATGGCCGAGA
AGATTCAGTTCGAATTGGTG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MANKNVGTITQVLGAVVDVRFDGQLPAILSALHLEHQGKKLVLEVAQHLGESTVRTIAMDSTDGLTRGTEVVDTGAAIQM
PVGPETLGRIINVIGEPIDERGPIGNKTTLPIHADAPEFVDQSTETEILVTGIKVIDLLAPYCKGGKIGLCGGAGVGKTV
LIMELINNIAKAHGGYSVFAGVGERTREGNDLYHEMIESGVIKLDGPGSKVALVYGQMNEPPGARARVALSGLTVAEYFR
DVEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKKGSITSVQAIYVPADDLTDPAPAT
SFAHLDATTVLNRQIAELGIYPAVDPLDSTSRVLDPRVVGNDHYQTARDVQRILQTYKSLQDIIAILGMDELSEEDKLVV
SRARKIQRFLSQPFHVAEIFTGSPGKLVAIDDTIKGFKAIVAGEYDHLPEAAFYMVGGIDEVIEKAKKMAAEAA

Sequences:

>Translated_474_residues
MANKNVGTITQVLGAVVDVRFDGQLPAILSALHLEHQGKKLVLEVAQHLGESTVRTIAMDSTDGLTRGTEVVDTGAAIQM
PVGPETLGRIINVIGEPIDERGPIGNKTTLPIHADAPEFVDQSTETEILVTGIKVIDLLAPYCKGGKIGLCGGAGVGKTV
LIMELINNIAKAHGGYSVFAGVGERTREGNDLYHEMIESGVIKLDGPGSKVALVYGQMNEPPGARARVALSGLTVAEYFR
DVEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKKGSITSVQAIYVPADDLTDPAPAT
SFAHLDATTVLNRQIAELGIYPAVDPLDSTSRVLDPRVVGNDHYQTARDVQRILQTYKSLQDIIAILGMDELSEEDKLVV
SRARKIQRFLSQPFHVAEIFTGSPGKLVAIDDTIKGFKAIVAGEYDHLPEAAFYMVGGIDEVIEKAKKMAAEAA
>Mature_473_residues
ANKNVGTITQVLGAVVDVRFDGQLPAILSALHLEHQGKKLVLEVAQHLGESTVRTIAMDSTDGLTRGTEVVDTGAAIQMP
VGPETLGRIINVIGEPIDERGPIGNKTTLPIHADAPEFVDQSTETEILVTGIKVIDLLAPYCKGGKIGLCGGAGVGKTVL
IMELINNIAKAHGGYSVFAGVGERTREGNDLYHEMIESGVIKLDGPGSKVALVYGQMNEPPGARARVALSGLTVAEYFRD
VEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATS
FAHLDATTVLNRQIAELGIYPAVDPLDSTSRVLDPRVVGNDHYQTARDVQRILQTYKSLQDIIAILGMDELSEEDKLVVS
RARKIQRFLSQPFHVAEIFTGSPGKLVAIDDTIKGFKAIVAGEYDHLPEAAFYMVGGIDEVIEKAKKMAAEAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=471, Percent_Identity=80.0424628450106, Blast_Score=766, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=301, Percent_Identity=28.2392026578073, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI50345984, Length=300, Percent_Identity=27, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4757810, Length=300, Percent_Identity=27, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19913426, Length=399, Percent_Identity=24.812030075188, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19913428, Length=417, Percent_Identity=24.7002398081535, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1790170, Length=464, Percent_Identity=70.0431034482759, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=313, Percent_Identity=31.629392971246, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790172, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=77.6824034334764, Blast_Score=745, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=301, Percent_Identity=28.9036544850498, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=25.3521126760563, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=388, Percent_Identity=23.9690721649485, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988080, Length=320, Percent_Identity=24.6875, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=320, Percent_Identity=24.375, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=272, Percent_Identity=23.8970588235294, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=77.0742358078603, Blast_Score=716, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=373, Percent_Identity=24.9329758713137, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=398, Percent_Identity=25.3768844221106, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24638766, Length=468, Percent_Identity=79.9145299145299, Blast_Score=762, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=466, Percent_Identity=71.244635193133, Blast_Score=676, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=90, Percent_Identity=66.6666666666667, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI20129479, Length=308, Percent_Identity=28.2467532467532, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24583988, Length=306, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583986, Length=306, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583984, Length=306, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583992, Length=306, Percent_Identity=29.0849673202614, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281361666, Length=362, Percent_Identity=25.6906077348066, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24646341, Length=362, Percent_Identity=25.6906077348066, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17136796, Length=362, Percent_Identity=25.6906077348066, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24658560, Length=300, Percent_Identity=26.6666666666667, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_MAGSA (Q2VZN2)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_423502.1
- HSSP:   P00829
- ProteinModelPortal:   Q2VZN2
- SMR:   Q2VZN2
- STRING:   Q2VZN2
- GeneID:   3803333
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb4139
- NMPDR:   fig|342108.5.peg.3719
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q2VZN2
- ProtClustDB:   PRK09280
- BioCyc:   MMAG342108:AMB4139-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50656; Mature: 50524

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKNVGTITQVLGAVVDVRFDGQLPAILSALHLEHQGKKLVLEVAQHLGESTVRTIAMD
CCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHEEEEC
STDGLTRGTEVVDTGAAIQMPVGPETLGRIINVIGEPIDERGPIGNKTTLPIHADAPEFV
CCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHH
DQSTETEILVTGIKVIDLLAPYCKGGKIGLCGGAGVGKTVLIMELINNIAKAHGGYSVFA
CCCCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEE
GVGERTREGNDLYHEMIESGVIKLDGPGSKVALVYGQMNEPPGARARVALSGLTVAEYFR
CCCCCCCCCHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHH
DVEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKKGSI
CCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCC
TSVQAIYVPADDLTDPAPATSFAHLDATTVLNRQIAELGIYPAVDPLDSTSRVLDPRVVG
EEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEECC
NDHYQTARDVQRILQTYKSLQDIIAILGMDELSEEDKLVVSRARKIQRFLSQPFHVAEIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
TGSPGKLVAIDDTIKGFKAIVAGEYDHLPEAAFYMVGGIDEVIEKAKKMAAEAA
ECCCCCEEEECCHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANKNVGTITQVLGAVVDVRFDGQLPAILSALHLEHQGKKLVLEVAQHLGESTVRTIAMD
CCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHEEEEC
STDGLTRGTEVVDTGAAIQMPVGPETLGRIINVIGEPIDERGPIGNKTTLPIHADAPEFV
CCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHH
DQSTETEILVTGIKVIDLLAPYCKGGKIGLCGGAGVGKTVLIMELINNIAKAHGGYSVFA
CCCCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEE
GVGERTREGNDLYHEMIESGVIKLDGPGSKVALVYGQMNEPPGARARVALSGLTVAEYFR
CCCCCCCCCHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHH
DVEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKKGSI
CCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCC
TSVQAIYVPADDLTDPAPATSFAHLDATTVLNRQIAELGIYPAVDPLDSTSRVLDPRVVG
EEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEECC
NDHYQTARDVQRILQTYKSLQDIIAILGMDELSEEDKLVVSRARKIQRFLSQPFHVAEIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
TGSPGKLVAIDDTIKGFKAIVAGEYDHLPEAAFYMVGGIDEVIEKAKKMAAEAA
ECCCCCEEEECCHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA