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The map label for this gene is aroB

Identifier: 83313024

GI number: 83313024

Start: 4337078

End: 4338193

Strand: Reverse

Name: aroB

Synonym: amb3925

Alternate gene names: 83313024

Gene position: 4338193-4337078 (Counterclockwise)

Preceding gene: 83313025

Following gene: 83313023

Centisome position: 87.34

GC content: 69.35

Gene sequence:

>1116_bases
ATGAGTGCCGCCGCCGAAGAGGTCATGGTCGAACTGGGCGAGCGCTCGTATCCGATCCATATCGGCCCCGGCCTGCTGGA
CCGGGCGGGCGAGCTGATCAAGCCGAAGATGCGGGGCGGCCGCGCCCTGGTGGTGACCGACGCCAACGTGGCGCCCCATT
ATCTAGAGCGGGTGCAGAAGAGCCTGGCCGAGGCCGGGGTGACCACCATGCATACGGTCATGCCCGCCGGCGAGCAGACC
AAGGACTTCAAGCATCTGGAAGCCCTGCTGGACGCCATGCTGGAAGCCCGCTCCGAGCGCGGCATCATGGTGGTGGCCCT
CGGCGGCGGCGTGGTGGGCGACCTCACCGGCTTTGCCGCCTCGATCCTGCTGCGCGGCGTGGATTTCGTGCAGATCCCCA
CCACCTTGCTGTCCCAGGTGGATTCCTCGGTGGGCGGCAAGACCGGCATCAACACCCGCCAGGGCAAGAACCTGATCGGC
AGCTTCTACCAGCCCCGGCTGGTGCTGGCCGACACCAGCGTGCTCAACACCCTGCCCCGGCGGCAGGTGCTGGCCGGCTA
TGCCGAGGTGGCCAAGTACGGGGTGATCGACGACGAACCGTTCTTCGCCTGGCTGGAGGAGAACGGGTCCAAAGTGGTGG
ACGGCGACCTGGAGGCCCGGCGTTACGCCGTCGCCACCTCGTGCCGCGCCAAGGCCCGCATCGTCGGCGCCGACGAGCGC
GAGGGCGGCGTGCGCGCCCTGCTCAATCTCGGCCACACCTTCGGCCATGCCCTGGAGGCCGAGACCGGCTTCTCCGAGGA
GATGCTGCACGGCGAGGCGGTGGCCATCGGCATGGTCATGGCGCTGCGCCTGTCGGCCCGCCTGGGGCTGGCCCCCGCGG
CCGACGCCGAGCGGCTGGAGCGTCACCTGCTGGCGGTGGGGCTGCCCGTCACCCTGCCCAAGCCCCGGCTGTGGGCGGTG
GACCGGCTGATTCACCACATGGCCGGCGACAAGAAGGTCAAGGACGGCAAGGTCACCTTCGTGATGGCCAAGGGCATCGG
CAAGAGCTTCCTGACCCGCGACGTGCCGGAAGCCGAGCTGGCCTCCATGCTGGCGGAGATGGCGTCGGGGTATTAG

Upstream 100 bases:

>100_bases
AAGCCGACATTATCGTCGAGTCCACCGACGAAGTCCCCGAAGCCACCGTGATCCGCGTCATGGAGGGGCTGATCACCTAT
CTGGATCTGGAGAAGACCGT

Downstream 100 bases:

>100_bases
AGCGGTGCGCACCCGGCAGGGGCAATCAAGGGGATAAGGCGATGTTGGACCAAGGGCCTCTCTTCCTGACCCTTTCAGTG
ATTGCCATCGTGGTGCTGCA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSAAAEEVMVELGERSYPIHIGPGLLDRAGELIKPKMRGGRALVVTDANVAPHYLERVQKSLAEAGVTTMHTVMPAGEQT
KDFKHLEALLDAMLEARSERGIMVVALGGGVVGDLTGFAASILLRGVDFVQIPTTLLSQVDSSVGGKTGINTRQGKNLIG
SFYQPRLVLADTSVLNTLPRRQVLAGYAEVAKYGVIDDEPFFAWLEENGSKVVDGDLEARRYAVATSCRAKARIVGADER
EGGVRALLNLGHTFGHALEAETGFSEEMLHGEAVAIGMVMALRLSARLGLAPAADAERLERHLLAVGLPVTLPKPRLWAV
DRLIHHMAGDKKVKDGKVTFVMAKGIGKSFLTRDVPEAELASMLAEMASGY

Sequences:

>Translated_371_residues
MSAAAEEVMVELGERSYPIHIGPGLLDRAGELIKPKMRGGRALVVTDANVAPHYLERVQKSLAEAGVTTMHTVMPAGEQT
KDFKHLEALLDAMLEARSERGIMVVALGGGVVGDLTGFAASILLRGVDFVQIPTTLLSQVDSSVGGKTGINTRQGKNLIG
SFYQPRLVLADTSVLNTLPRRQVLAGYAEVAKYGVIDDEPFFAWLEENGSKVVDGDLEARRYAVATSCRAKARIVGADER
EGGVRALLNLGHTFGHALEAETGFSEEMLHGEAVAIGMVMALRLSARLGLAPAADAERLERHLLAVGLPVTLPKPRLWAV
DRLIHHMAGDKKVKDGKVTFVMAKGIGKSFLTRDVPEAELASMLAEMASGY
>Mature_370_residues
SAAAEEVMVELGERSYPIHIGPGLLDRAGELIKPKMRGGRALVVTDANVAPHYLERVQKSLAEAGVTTMHTVMPAGEQTK
DFKHLEALLDAMLEARSERGIMVVALGGGVVGDLTGFAASILLRGVDFVQIPTTLLSQVDSSVGGKTGINTRQGKNLIGS
FYQPRLVLADTSVLNTLPRRQVLAGYAEVAKYGVIDDEPFFAWLEENGSKVVDGDLEARRYAVATSCRAKARIVGADERE
GGVRALLNLGHTFGHALEAETGFSEEMLHGEAVAIGMVMALRLSARLGLAPAADAERLERHLLAVGLPVTLPKPRLWAVD
RLIHHMAGDKKVKDGKVTFVMAKGIGKSFLTRDVPEAELASMLAEMASGY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=364, Percent_Identity=48.0769230769231, Blast_Score=300, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6320332, Length=373, Percent_Identity=37.2654155495979, Blast_Score=207, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39743; Mature: 39611

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAAEEVMVELGERSYPIHIGPGLLDRAGELIKPKMRGGRALVVTDANVAPHYLERVQK
CCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCHHHCCCCEEEEECCCCCHHHHHHHHH
SLAEAGVTTMHTVMPAGEQTKDFKHLEALLDAMLEARSERGIMVVALGGGVVGDLTGFAA
HHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
SILLRGVDFVQIPTTLLSQVDSSVGGKTGINTRQGKNLIGSFYQPRLVLADTSVLNTLPR
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCEEEEECCHHHHHCHH
RQVLAGYAEVAKYGVIDDEPFFAWLEENGSKVVDGDLEARRYAVATSCRAKARIVGADER
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCEEEECCCCC
EGGVRALLNLGHTFGHALEAETGFSEEMLHGEAVAIGMVMALRLSARLGLAPAADAERLE
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RHLLAVGLPVTLPKPRLWAVDRLIHHMAGDKKVKDGKVTFVMAKGIGKSFLTRDVPEAEL
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCHHHHHCCCCHHHH
ASMLAEMASGY
HHHHHHHHCCC
>Mature Secondary Structure 
SAAAEEVMVELGERSYPIHIGPGLLDRAGELIKPKMRGGRALVVTDANVAPHYLERVQK
CHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCHHHCCCCEEEEECCCCCHHHHHHHHH
SLAEAGVTTMHTVMPAGEQTKDFKHLEALLDAMLEARSERGIMVVALGGGVVGDLTGFAA
HHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
SILLRGVDFVQIPTTLLSQVDSSVGGKTGINTRQGKNLIGSFYQPRLVLADTSVLNTLPR
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCEEEEECCHHHHHCHH
RQVLAGYAEVAKYGVIDDEPFFAWLEENGSKVVDGDLEARRYAVATSCRAKARIVGADER
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCEEEECCCCC
EGGVRALLNLGHTFGHALEAETGFSEEMLHGEAVAIGMVMALRLSARLGLAPAADAERLE
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RHLLAVGLPVTLPKPRLWAVDRLIHHMAGDKKVKDGKVTFVMAKGIGKSFLTRDVPEAEL
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCHHHHHCCCCHHHH
ASMLAEMASGY
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA