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The map label for this gene is nadA [H]

Identifier: 83312985

GI number: 83312985

Start: 4293706

End: 4294728

Strand: Reverse

Name: nadA [H]

Synonym: amb3886

Alternate gene names: 83312985

Gene position: 4294728-4293706 (Counterclockwise)

Preceding gene: 83312987

Following gene: 83312984

Centisome position: 86.46

GC content: 63.73

Gene sequence:

>1023_bases
ATGACCGACACCATTGTTTTGCCCGCGCCCGGCGCCATGACCGAAGCCGACATCGACCCGACCCTCGATCTGGTCGCCGA
GATCGACCGCCTGCGCAAGGAGCGCAACGCGGTGATTCTGGCCCATTACTACCAAGAGGGCGAGATTCAGGACCTGGCGG
ACTTCGTCGGCGATTCGCTCGACCTGTCGCGCAAGGCGGCGGCCACCGATGCGGACATGATCGTGTTCTGCGGCGTGCGC
TTCATGGGCGAGGTGGCCAAGATACTGTCGCCGTCCAAGCTGGTGGTGATCCCCGATTCCGAAGCCGGCTGCTCGCTGGA
GGAATCCTGTCGCCCCGAGCCGTTCCGCGCTTTCCGGGAAAAGCACCCCGACCATATCGCGGTCACCTACATCAACTGCT
CGGCCGAGGTGAAGGCGCTGTCCGACGTGATCGTCACCTCGTCCAATGCCGAGGCGATCATTAGCCAACTGCCCGCCGAC
CGCCCCATCCTGTTCGCGCCCGACCGCCATCTGGGCGCCTATATGCAGAAGAAGACCGGGCGCGACATGACGCTGTGGCC
GGGCAGCTGCATCATCCACGAGCAATTCTCCGAGAAGGAGCTGGTCAAGCTGAAGGTTCGCCATCCCAAGGCCCTGGTGG
CGGCGCATCCGGAATGCCCGGACAGCATCCTGAACCATGCCGACCATGTGGGCTCGACCCGCAACATCCTGGATTTCGTG
CTGGCCAGCTCGGCCAAGGAATTCATCATCGCCACCGAGCAGCACATCATCCATCAGATGAGCAAGGCGGCGCCCGACAA
GACCTTCATTCCGGCCCCCGGCGCCGATGGCGGCTGTTCGTGCTCCAACTGCCCGTTCATGGCCAGGAACACCCTGGAGA
AGATCTATCTCTGCCTGAAGAACGACGCCCCCGCCATCACCGTGCCCGAGGATCTGCGCGTCGCGGCCCTGAAGCCGCTG
GAGCGCATGCTGGAGATGAGCAAGTCGGTCCCCATGTCCGGAGACAAGCCCAATGCGGCCTGA

Upstream 100 bases:

>100_bases
TGTCGGGGTGGGTGAAGGGTTGCTTTGCCCCCGCGATTCGTCCTTTACTTCCCCCTTAGTGAAGCGGGGGAATCCGTCCC
CCGGGAGAGAGCCCAGACCG

Downstream 100 bases:

>100_bases
GGCGGAGCTTGACTGGGACGACGCGCGGCGGGTCATCCTCGCCGCGCTGGCCGAGGACACGGGGGCGGACAAGGGCGGCG
AAGGCGAGGACATCACCTCG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTDTIVLPAPGAMTEADIDPTLDLVAEIDRLRKERNAVILAHYYQEGEIQDLADFVGDSLDLSRKAAATDADMIVFCGVR
FMGEVAKILSPSKLVVIPDSEAGCSLEESCRPEPFRAFREKHPDHIAVTYINCSAEVKALSDVIVTSSNAEAIISQLPAD
RPILFAPDRHLGAYMQKKTGRDMTLWPGSCIIHEQFSEKELVKLKVRHPKALVAAHPECPDSILNHADHVGSTRNILDFV
LASSAKEFIIATEQHIIHQMSKAAPDKTFIPAPGADGGCSCSNCPFMARNTLEKIYLCLKNDAPAITVPEDLRVAALKPL
ERMLEMSKSVPMSGDKPNAA

Sequences:

>Translated_340_residues
MTDTIVLPAPGAMTEADIDPTLDLVAEIDRLRKERNAVILAHYYQEGEIQDLADFVGDSLDLSRKAAATDADMIVFCGVR
FMGEVAKILSPSKLVVIPDSEAGCSLEESCRPEPFRAFREKHPDHIAVTYINCSAEVKALSDVIVTSSNAEAIISQLPAD
RPILFAPDRHLGAYMQKKTGRDMTLWPGSCIIHEQFSEKELVKLKVRHPKALVAAHPECPDSILNHADHVGSTRNILDFV
LASSAKEFIIATEQHIIHQMSKAAPDKTFIPAPGADGGCSCSNCPFMARNTLEKIYLCLKNDAPAITVPEDLRVAALKPL
ERMLEMSKSVPMSGDKPNAA
>Mature_339_residues
TDTIVLPAPGAMTEADIDPTLDLVAEIDRLRKERNAVILAHYYQEGEIQDLADFVGDSLDLSRKAAATDADMIVFCGVRF
MGEVAKILSPSKLVVIPDSEAGCSLEESCRPEPFRAFREKHPDHIAVTYINCSAEVKALSDVIVTSSNAEAIISQLPADR
PILFAPDRHLGAYMQKKTGRDMTLWPGSCIIHEQFSEKELVKLKVRHPKALVAAHPECPDSILNHADHVGSTRNILDFVL
ASSAKEFIIATEQHIIHQMSKAAPDKTFIPAPGADGGCSCSNCPFMARNTLEKIYLCLKNDAPAITVPEDLRVAALKPLE
RMLEMSKSVPMSGDKPNAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=338, Percent_Identity=42.3076923076923, Blast_Score=259, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37126; Mature: 36995

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTIVLPAPGAMTEADIDPTLDLVAEIDRLRKERNAVILAHYYQEGEIQDLADFVGDSL
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCC
DLSRKAAATDADMIVFCGVRFMGEVAKILSPSKLVVIPDSEAGCSLEESCRPEPFRAFRE
CCHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCHHHHHHH
KHPDHIAVTYINCSAEVKALSDVIVTSSNAEAIISQLPADRPILFAPDRHLGAYMQKKTG
CCCCEEEEEEEECCHHHHHHHHHEEECCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHCC
RDMTLWPGSCIIHEQFSEKELVKLKVRHPKALVAAHPECPDSILNHADHVGSTRNILDFV
CCEEECCCCEEEECCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHH
LASSAKEFIIATEQHIIHQMSKAAPDKTFIPAPGADGGCSCSNCPFMARNTLEKIYLCLK
HHCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
NDAPAITVPEDLRVAALKPLERMLEMSKSVPMSGDKPNAA
CCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TDTIVLPAPGAMTEADIDPTLDLVAEIDRLRKERNAVILAHYYQEGEIQDLADFVGDSL
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCC
DLSRKAAATDADMIVFCGVRFMGEVAKILSPSKLVVIPDSEAGCSLEESCRPEPFRAFRE
CCHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCHHHHHHH
KHPDHIAVTYINCSAEVKALSDVIVTSSNAEAIISQLPADRPILFAPDRHLGAYMQKKTG
CCCCEEEEEEEECCHHHHHHHHHEEECCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHCC
RDMTLWPGSCIIHEQFSEKELVKLKVRHPKALVAAHPECPDSILNHADHVGSTRNILDFV
CCEEECCCCEEEECCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHH
LASSAKEFIIATEQHIIHQMSKAAPDKTFIPAPGADGGCSCSNCPFMARNTLEKIYLCLK
HHCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
NDAPAITVPEDLRVAALKPLERMLEMSKSVPMSGDKPNAA
CCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA