Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 83312898

GI number: 83312898

Start: 4195267

End: 4195827

Strand: Reverse

Name: pgsA [H]

Synonym: amb3799

Alternate gene names: 83312898

Gene position: 4195827-4195267 (Counterclockwise)

Preceding gene: 83312899

Following gene: 83312897

Centisome position: 84.47

GC content: 66.84

Gene sequence:

>561_bases
ATGCTGACCAGCCTTCCCAACCTGCTGACACTGTCGCGGATCGTCGTGATTCCGTTGGTGGTCGGCCTGTTCTACGTGGA
CGGCGACGCCGCCCGCTGGGCCGCCTGCGCCCTGTTCGTGGCCGCCGCCGTCACCGACTGGTTCGACGGCTATCTGGCGC
GGTCGTGGAACCAGGTGTCCAAGTTCGGGCGCTTCCTCGACCCCATCGCCGACAAGCTGCTGGTGGCTTCGGTGCTGTTC
ATGCTGGCCGCCTTCGACCGGCTCAGCACGGTGTCCTTCCTGCCTGCCCTGGTCATCGTGCTGCGCGAGATCCTGGTCTC
GGGCCTGCGCGAATTCCTGGCCGAGGTGCGGGTGGGCATGCCGGTGTCCCGGCTGGCCAAGTGGAAGACCGCCATTCAGA
TGACCGCCATTCCGGTGCTGCTGGTGGGCGACGCCGCCACCTTCATGCCCACCCGGCTGGTGGGCGAGGTCGGCCTATGG
GCTGCCGCCATCCTGACCATCATTACCGGCTGGGACTACCTGCGCTCGGGCATGAGCCATATGGGGGAATCGGCGGAATG
A

Upstream 100 bases:

>100_bases
GGCCGGTCTGCCCGATCTGGAAAGCGTCGAGGGAATCAGCCACGCCATGGCCAAAAAGATTCATGACTACTTCCATCCCG
AGGGTTAGTATCCCGGCGTT

Downstream 100 bases:

>100_bases
AGGTGTTCGGCATCGCCGGGCGCTCCGGCATGGGCAAGACCTCGCTGATCATCCGCCTGATTCCCTGGTTTCGCGCCCAA
GGCATCACCATCTCCACCGT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLTSLPNLLTLSRIVVIPLVVGLFYVDGDAARWAACALFVAAAVTDWFDGYLARSWNQVSKFGRFLDPIADKLLVASVLF
MLAAFDRLSTVSFLPALVIVLREILVSGLREFLAEVRVGMPVSRLAKWKTAIQMTAIPVLLVGDAATFMPTRLVGEVGLW
AAAILTIITGWDYLRSGMSHMGESAE

Sequences:

>Translated_186_residues
MLTSLPNLLTLSRIVVIPLVVGLFYVDGDAARWAACALFVAAAVTDWFDGYLARSWNQVSKFGRFLDPIADKLLVASVLF
MLAAFDRLSTVSFLPALVIVLREILVSGLREFLAEVRVGMPVSRLAKWKTAIQMTAIPVLLVGDAATFMPTRLVGEVGLW
AAAILTIITGWDYLRSGMSHMGESAE
>Mature_186_residues
MLTSLPNLLTLSRIVVIPLVVGLFYVDGDAARWAACALFVAAAVTDWFDGYLARSWNQVSKFGRFLDPIADKLLVASVLF
MLAAFDRLSTVSFLPALVIVLREILVSGLREFLAEVRVGMPVSRLAKWKTAIQMTAIPVLLVGDAATFMPTRLVGEVGLW
AAAILTIITGWDYLRSGMSHMGESAE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=186, Percent_Identity=40.3225806451613, Blast_Score=116, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6320059, Length=155, Percent_Identity=30.3225806451613, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650130, Length=84, Percent_Identity=45.2380952380952, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24650126, Length=84, Percent_Identity=45.2380952380952, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24650128, Length=84, Percent_Identity=45.2380952380952, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20289; Mature: 20289

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSLPNLLTLSRIVVIPLVVGLFYVDGDAARWAACALFVAAAVTDWFDGYLARSWNQVS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGRFLDPIADKLLVASVLFMLAAFDRLSTVSFLPALVIVLREILVSGLREFLAEVRVGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVSRLAKWKTAIQMTAIPVLLVGDAATFMPTRLVGEVGLWAAAILTIITGWDYLRSGMSH
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGESAE
CCCCCC
>Mature Secondary Structure
MLTSLPNLLTLSRIVVIPLVVGLFYVDGDAARWAACALFVAAAVTDWFDGYLARSWNQVS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGRFLDPIADKLLVASVLFMLAAFDRLSTVSFLPALVIVLREILVSGLREFLAEVRVGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVSRLAKWKTAIQMTAIPVLLVGDAATFMPTRLVGEVGLWAAAILTIITGWDYLRSGMSH
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGESAE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA