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The map label for this gene is aphA [H]

Identifier: 83312754

GI number: 83312754

Start: 4019699

End: 4020832

Strand: Reverse

Name: aphA [H]

Synonym: amb3655

Alternate gene names: 83312754

Gene position: 4020832-4019699 (Counterclockwise)

Preceding gene: 83312755

Following gene: 83312753

Centisome position: 80.95

GC content: 63.32

Gene sequence:

>1134_bases
ATGCAGAACGACGAATTGCGGCGGGCCCAACTGGCTCTGGAAGAATCCCGCGACCGCTATGTCGATCTCTTTGAATTCGC
TCCGGTCGGCTATCTAATCCTGTCCCGTATTGGGGTAATCACCCAGATCAACCTGACCGGCGCGGCCTTGCTGGGAGTGG
AGCGCGCCGGGGTGATTGCCCAGCGCTTCGACGCCTTCGTCGCCGGCACCGACCATGACCGCTGGCATCGGCATCTGGCG
CATGCCCTCCACCATACCGGCCGGCACGAATGCGAGCTTGTCCTTCTGCGGGCGGACGGCAGGAACTTCAACGGCCATCT
CGATTGCCAGTTGCAGGAACAGGACGCAGCCCCGGTCCTGCGCGTCGCTCTGACCGATATCACGGTGCGCAAGACGGCCG
AGGCGGAACTGGCTGATACCCGCGAGGCGCTGCTGCGGGCTAACGAGAGACTGCGAGCCTCGAACCGGGACCTCGAGCAA
TTCGCCTACGTGGCCTCCCACGACTTGCAGGAGCCGCTGCGCATGGTGGTCAGCTATGGCCAACTGCTGGAAAGGAAGTA
TCACGACCGGCTGGACGACGACGCCCATACCTTCATCGACTTCATGGTCGAGGGCGGGGCCAGAATGCAGGCCATGGTCA
CCGACCTGCTGGAATTCTCGCGGGTCGACCGCATGGGAGGAGAGCGGGAGCCGTTCGACAGCGGCAAGGCGGTGGAGGAA
GCCAAGTTCAGCCTATCCCAGGCCATCGCGGAATCCGGCGCCGAGATCGGTCATGCCGGTCTGCCGGAGATCGTCTACGA
TAGCCACCAGTTCGTCCGGCTGATGCAAAACCTGATCGGTAACGCCCTTAAGTATCACGACCCGGGCCGACCGCCCAAGG
TCACCGTCACCGCCCGCCGCGACGGGCATCAATGGGAGTTTTCCGTCAGCGACAACGGCATCGGAATCGACCCGGCCTAT
TTCGAGCAGATATTCGCCGTTTTTCGCCGCCTCCATACCCGCGACCGGTACGGAGGCACCGGTATCGGCCTTGCCGTCTG
CAAGAAGATCGTCGAACATCATGGCGGTCGCATCTGGGTGGAATCGACCCCCGGGGCGGGCAGCGCGTTTTTCTTCACGG
CACCGGACCCCTGA

Upstream 100 bases:

>100_bases
GTGGAAAGGGGCTTTGATGAACCAGCACCCTGGCGACGAAACGCCGCCGTCACCAGAACACCTGCTCCACGAACTCCGCG
TCCACCAGATCGAACTGGAG

Downstream 100 bases:

>100_bases
CGCACCTGCGCCAAGGGCACGCAATCCCGCCAGGGCTCAGGAGTATTTCCGGTGACGAGCAAGACCTTGCCTCAGCCCCC
CGCGGCCGAACTGTCCATTG

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MQNDELRRAQLALEESRDRYVDLFEFAPVGYLILSRIGVITQINLTGAALLGVERAGVIAQRFDAFVAGTDHDRWHRHLA
HALHHTGRHECELVLLRADGRNFNGHLDCQLQEQDAAPVLRVALTDITVRKTAEAELADTREALLRANERLRASNRDLEQ
FAYVASHDLQEPLRMVVSYGQLLERKYHDRLDDDAHTFIDFMVEGGARMQAMVTDLLEFSRVDRMGGEREPFDSGKAVEE
AKFSLSQAIAESGAEIGHAGLPEIVYDSHQFVRLMQNLIGNALKYHDPGRPPKVTVTARRDGHQWEFSVSDNGIGIDPAY
FEQIFAVFRRLHTRDRYGGTGIGLAVCKKIVEHHGGRIWVESTPGAGSAFFFTAPDP

Sequences:

>Translated_377_residues
MQNDELRRAQLALEESRDRYVDLFEFAPVGYLILSRIGVITQINLTGAALLGVERAGVIAQRFDAFVAGTDHDRWHRHLA
HALHHTGRHECELVLLRADGRNFNGHLDCQLQEQDAAPVLRVALTDITVRKTAEAELADTREALLRANERLRASNRDLEQ
FAYVASHDLQEPLRMVVSYGQLLERKYHDRLDDDAHTFIDFMVEGGARMQAMVTDLLEFSRVDRMGGEREPFDSGKAVEE
AKFSLSQAIAESGAEIGHAGLPEIVYDSHQFVRLMQNLIGNALKYHDPGRPPKVTVTARRDGHQWEFSVSDNGIGIDPAY
FEQIFAVFRRLHTRDRYGGTGIGLAVCKKIVEHHGGRIWVESTPGAGSAFFFTAPDP
>Mature_377_residues
MQNDELRRAQLALEESRDRYVDLFEFAPVGYLILSRIGVITQINLTGAALLGVERAGVIAQRFDAFVAGTDHDRWHRHLA
HALHHTGRHECELVLLRADGRNFNGHLDCQLQEQDAAPVLRVALTDITVRKTAEAELADTREALLRANERLRASNRDLEQ
FAYVASHDLQEPLRMVVSYGQLLERKYHDRLDDDAHTFIDFMVEGGARMQAMVTDLLEFSRVDRMGGEREPFDSGKAVEE
AKFSLSQAIAESGAEIGHAGLPEIVYDSHQFVRLMQNLIGNALKYHDPGRPPKVTVTARRDGHQWEFSVSDNGIGIDPAY
FEQIFAVFRRLHTRDRYGGTGIGLAVCKKIVEHHGGRIWVESTPGAGSAFFFTAPDP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=225, Percent_Identity=28, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=26.5822784810127, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=26.6393442622951, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=24.0458015267176, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=29.0836653386454, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788549, Length=380, Percent_Identity=22.8947368421053, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=27.9661016949153, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=267, Percent_Identity=25.4681647940075, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788713, Length=279, Percent_Identity=23.2974910394265, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42334; Mature: 42334

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNDELRRAQLALEESRDRYVDLFEFAPVGYLILSRIGVITQINLTGAALLGVERAGVIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCHHHHHHHHHHHHHH
QRFDAFVAGTDHDRWHRHLAHALHHTGRHECELVLLRADGRNFNGHLDCQLQEQDAAPVL
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHH
RVALTDITVRKTAEAELADTREALLRANERLRASNRDLEQFAYVASHDLQEPLRMVVSYG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLLERKYHDRLDDDAHTFIDFMVEGGARMQAMVTDLLEFSRVDRMGGEREPFDSGKAVEE
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AKFSLSQAIAESGAEIGHAGLPEIVYDSHQFVRLMQNLIGNALKYHDPGRPPKVTVTARR
HHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
DGHQWEFSVSDNGIGIDPAYFEQIFAVFRRLHTRDRYGGTGIGLAVCKKIVEHHGGRIWV
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
ESTPGAGSAFFFTAPDP
ECCCCCCCEEEEECCCC
>Mature Secondary Structure
MQNDELRRAQLALEESRDRYVDLFEFAPVGYLILSRIGVITQINLTGAALLGVERAGVIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCHHHHHHHHHHHHHH
QRFDAFVAGTDHDRWHRHLAHALHHTGRHECELVLLRADGRNFNGHLDCQLQEQDAAPVL
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHH
RVALTDITVRKTAEAELADTREALLRANERLRASNRDLEQFAYVASHDLQEPLRMVVSYG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLLERKYHDRLDDDAHTFIDFMVEGGARMQAMVTDLLEFSRVDRMGGEREPFDSGKAVEE
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AKFSLSQAIAESGAEIGHAGLPEIVYDSHQFVRLMQNLIGNALKYHDPGRPPKVTVTARR
HHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
DGHQWEFSVSDNGIGIDPAYFEQIFAVFRRLHTRDRYGGTGIGLAVCKKIVEHHGGRIWV
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
ESTPGAGSAFFFTAPDP
ECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]