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The map label for this gene is cph1 [H]

Identifier: 83312635

GI number: 83312635

Start: 3886158

End: 3887981

Strand: Reverse

Name: cph1 [H]

Synonym: amb3536

Alternate gene names: 83312635

Gene position: 3887981-3886158 (Counterclockwise)

Preceding gene: 83312643

Following gene: 83312634

Centisome position: 78.27

GC content: 64.75

Gene sequence:

>1824_bases
ATGCCTTGGCAAGTTGGCTATTATGCTTTTCGTTGGCAAGTCCGGGGCGGGTGCGGGGCGCGCCGAAGAGAGGGGCGGAA
TCCATCGGATGTTCACCGTGACCAGGTTCATCGCGCGTCTGTCATGAGCGAGCGCAGGCGAATTCTCATTCTGATCGCCG
TCGTTCAGACGGTGGGTCTGGCGGCGCTGCTGATGCTGCCGCCGGGCCCGCCGGCCTGGGCGGTGGCTGGTCTCGGGGTG
GCGCTGACCCTGGTGCTGGTGGCGCGGTGCGGCCGGGCCGAAGGGGCCGCCCTCCAAGCCCTGCGGGCCGAGATTGGGCC
GCTGCGCAAGGAGCGCGACCGCCTCAGCCTGCTCTCCGAGGTGGTCAAGGAAAGCTCGGAACGCTATCGCGAATATTCCG
AGGCCGCCGCCGACTGGTTCTGGGAGAGCGACGCGGAACAGCGCTTCACCTTCTTCTCGTCGTCCTTCGAGACGGTGATG
AACATCATGTCCGACGACCTGCTGGGTAAGCGTTCGTGGGACATCGTCAGCGAGCGCATGGAGATCGATTCCGACCAGTG
GCAGGCCCATATCGCCGATCTGACCGCCCAGCGGCCGTTCCGCGACTTCAAGTACTGGCTGGAAGACGGTAACGGCCGGG
CGCGGTGGATCAAGGTCAACGGCCTGCCCCGGTTCGACGATGACGGCGTGTTCATCGGCTATCGCGGCACCGGCAGCGAC
ATCACCGCCGCGGTGGAGAACGCCCACCGCATGCACATGCTGAACCGCGCGGTGGAGCAGAGCCCCGTCTCCATCGTCAT
TACCGATCTCAACGCCGAGATCCAGTACGTCAACAGCAGTTTCCTGCGGATCACCGGCTATTCCATGGACGAGGTGATTG
GCCGCAACCCCCGCATCCTCAGGTCCGACACCACGCCGCCGGAAACCTTCCAGAACATGTGGGCCGCGCTGTCGGCCGGC
GAGAAGTGGGAAGGCGAGCTGATCAACCGGCGCAAAAGCGGAGAGCTTTACTGGGAACAGGCCACCATTCAGCCGATCCA
GAACATCGAAGGAGTCATCACCAACTACCTGGCCGTCAAGAGCGACATCACCGAGCAGAAGAAGGCCGCCGCCAAGCTGG
CCGAACTGGTGGAGGAACTGCGCCGCTCCAACGAGGAACTGGAACAGTTCGCCTATGTGGCCTCCCACGACCTGCGCCAG
CCCCTGCGCATGATCAGCGCCTATCTCGCCCTGTTGGAAAAGAAGCTTTCCGCCAGCTTCGACCAGGACGCCCGCGACTT
CTTCGGCTTTGCCATCGACGGCGCCCGGCGCCTGGACCGCATGATCGTCGATCTGCTGGAATATTCGCGCATCGGCCGCA
TCACCGCCCCCATGGAGCCGGTCAGCCTGGGCGAGGTAGTGAGCAATGCCCTCCGCTATCTCGAAGTGGCCGTCGCCGAG
AGCGGCTCCGAGGTGGTGGTGCCGGACGGTCTTCCGACCATTTCCGGCGATGGCGGCGAACTGGTCCGCCTGTTCCAGAA
CCTGATCGCCAATGCCATCAAGTACATGCCCGAAGGCCGCCAGCCGCGCATCGAGGTGCTCTGCCGCGCCCAGGGGGCGG
AATGGGTCGTGGGAGTCAAGGACAACGGCATCGGCATTCCTCCCGACGACCTGAAGCGGGTGTTCGGCATTTTCCAGCGC
CTGGTCGCCCGCGAGCAGTTCGAGGGCACCGGCATCGGCCTGGCGGTCTGCCGCAAGATCGCCGAGCACCACGGCGGACG
CATCTGGGTCGAGTCCGAAATGGGCGTCGGCAGCACCTTCCTCGTGGCTTTTCCCAAGGCCTGA

Upstream 100 bases:

>100_bases
GACAGAGCAAGGCTGCGATGACGATCGGTCTCATGGTCCTCTCCCGGCGGATAAGGATGGATCGGGAACATATTGTGTCA
TTGATATCATCCAAGGTGCC

Downstream 100 bases:

>100_bases
TTGCGACTTTTCCATATCGCTCCGATATCGCTTAACAGCCTATGCGGATCAGACTACCATTCACGTGGATACATGGGCGG
CCATTGAGGCCGCGCTAAGC

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MPWQVGYYAFRWQVRGGCGARRREGRNPSDVHRDQVHRASVMSERRRILILIAVVQTVGLAALLMLPPGPPAWAVAGLGV
ALTLVLVARCGRAEGAALQALRAEIGPLRKERDRLSLLSEVVKESSERYREYSEAAADWFWESDAEQRFTFFSSSFETVM
NIMSDDLLGKRSWDIVSERMEIDSDQWQAHIADLTAQRPFRDFKYWLEDGNGRARWIKVNGLPRFDDDGVFIGYRGTGSD
ITAAVENAHRMHMLNRAVEQSPVSIVITDLNAEIQYVNSSFLRITGYSMDEVIGRNPRILRSDTTPPETFQNMWAALSAG
EKWEGELINRRKSGELYWEQATIQPIQNIEGVITNYLAVKSDITEQKKAAAKLAELVEELRRSNEELEQFAYVASHDLRQ
PLRMISAYLALLEKKLSASFDQDARDFFGFAIDGARRLDRMIVDLLEYSRIGRITAPMEPVSLGEVVSNALRYLEVAVAE
SGSEVVVPDGLPTISGDGGELVRLFQNLIANAIKYMPEGRQPRIEVLCRAQGAEWVVGVKDNGIGIPPDDLKRVFGIFQR
LVAREQFEGTGIGLAVCRKIAEHHGGRIWVESEMGVGSTFLVAFPKA

Sequences:

>Translated_607_residues
MPWQVGYYAFRWQVRGGCGARRREGRNPSDVHRDQVHRASVMSERRRILILIAVVQTVGLAALLMLPPGPPAWAVAGLGV
ALTLVLVARCGRAEGAALQALRAEIGPLRKERDRLSLLSEVVKESSERYREYSEAAADWFWESDAEQRFTFFSSSFETVM
NIMSDDLLGKRSWDIVSERMEIDSDQWQAHIADLTAQRPFRDFKYWLEDGNGRARWIKVNGLPRFDDDGVFIGYRGTGSD
ITAAVENAHRMHMLNRAVEQSPVSIVITDLNAEIQYVNSSFLRITGYSMDEVIGRNPRILRSDTTPPETFQNMWAALSAG
EKWEGELINRRKSGELYWEQATIQPIQNIEGVITNYLAVKSDITEQKKAAAKLAELVEELRRSNEELEQFAYVASHDLRQ
PLRMISAYLALLEKKLSASFDQDARDFFGFAIDGARRLDRMIVDLLEYSRIGRITAPMEPVSLGEVVSNALRYLEVAVAE
SGSEVVVPDGLPTISGDGGELVRLFQNLIANAIKYMPEGRQPRIEVLCRAQGAEWVVGVKDNGIGIPPDDLKRVFGIFQR
LVAREQFEGTGIGLAVCRKIAEHHGGRIWVESEMGVGSTFLVAFPKA
>Mature_606_residues
PWQVGYYAFRWQVRGGCGARRREGRNPSDVHRDQVHRASVMSERRRILILIAVVQTVGLAALLMLPPGPPAWAVAGLGVA
LTLVLVARCGRAEGAALQALRAEIGPLRKERDRLSLLSEVVKESSERYREYSEAAADWFWESDAEQRFTFFSSSFETVMN
IMSDDLLGKRSWDIVSERMEIDSDQWQAHIADLTAQRPFRDFKYWLEDGNGRARWIKVNGLPRFDDDGVFIGYRGTGSDI
TAAVENAHRMHMLNRAVEQSPVSIVITDLNAEIQYVNSSFLRITGYSMDEVIGRNPRILRSDTTPPETFQNMWAALSAGE
KWEGELINRRKSGELYWEQATIQPIQNIEGVITNYLAVKSDITEQKKAAAKLAELVEELRRSNEELEQFAYVASHDLRQP
LRMISAYLALLEKKLSASFDQDARDFFGFAIDGARRLDRMIVDLLEYSRIGRITAPMEPVSLGEVVSNALRYLEVAVAES
GSEVVVPDGLPTISGDGGELVRLFQNLIANAIKYMPEGRQPRIEVLCRAQGAEWVVGVKDNGIGIPPDDLKRVFGIFQRL
VAREQFEGTGIGLAVCRKIAEHHGGRIWVESEMGVGSTFLVAFPKA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=30.7392996108949, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=32.7659574468085, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=353, Percent_Identity=24.6458923512748, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=29.2372881355932, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=28.0632411067194, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789453, Length=103, Percent_Identity=34.9514563106796, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786783, Length=274, Percent_Identity=25.5474452554745, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=22.093023255814, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=27.8260869565217, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=26.984126984127, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790551, Length=254, Percent_Identity=26.3779527559055, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68121; Mature: 67990

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWQVGYYAFRWQVRGGCGARRREGRNPSDVHRDQVHRASVMSERRRILILIAVVQTVGL
CCCCCCEEEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AALLMLPPGPPAWAVAGLGVALTLVLVARCGRAEGAALQALRAEIGPLRKERDRLSLLSE
HHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
VVKESSERYREYSEAAADWFWESDAEQRFTFFSSSFETVMNIMSDDLLGKRSWDIVSERM
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EIDSDQWQAHIADLTAQRPFRDFKYWLEDGNGRARWIKVNGLPRFDDDGVFIGYRGTGSD
HCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCH
ITAAVENAHRMHMLNRAVEQSPVSIVITDLNAEIQYVNSSFLRITGYSMDEVIGRNPRIL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEECCCHHHHHCCCCCEE
RSDTTPPETFQNMWAALSAGEKWEGELINRRKSGELYWEQATIQPIQNIEGVITNYLAVK
ECCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
SDITEQKKAAAKLAELVEELRRSNEELEQFAYVASHDLRQPLRMISAYLALLEKKLSASF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQDARDFFGFAIDGARRLDRMIVDLLEYSRIGRITAPMEPVSLGEVVSNALRYLEVAVAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
SGSEVVVPDGLPTISGDGGELVRLFQNLIANAIKYMPEGRQPRIEVLCRAQGAEWVVGVK
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCEEEEEC
DNGIGIPPDDLKRVFGIFQRLVAREQFEGTGIGLAVCRKIAEHHGGRIWVESEMGVGSTF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEE
LVAFPKA
EEEECCC
>Mature Secondary Structure 
PWQVGYYAFRWQVRGGCGARRREGRNPSDVHRDQVHRASVMSERRRILILIAVVQTVGL
CCCCCEEEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AALLMLPPGPPAWAVAGLGVALTLVLVARCGRAEGAALQALRAEIGPLRKERDRLSLLSE
HHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
VVKESSERYREYSEAAADWFWESDAEQRFTFFSSSFETVMNIMSDDLLGKRSWDIVSERM
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EIDSDQWQAHIADLTAQRPFRDFKYWLEDGNGRARWIKVNGLPRFDDDGVFIGYRGTGSD
HCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCH
ITAAVENAHRMHMLNRAVEQSPVSIVITDLNAEIQYVNSSFLRITGYSMDEVIGRNPRIL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEECCCHHHHHCCCCCEE
RSDTTPPETFQNMWAALSAGEKWEGELINRRKSGELYWEQATIQPIQNIEGVITNYLAVK
ECCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
SDITEQKKAAAKLAELVEELRRSNEELEQFAYVASHDLRQPLRMISAYLALLEKKLSASF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQDARDFFGFAIDGARRLDRMIVDLLEYSRIGRITAPMEPVSLGEVVSNALRYLEVAVAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
SGSEVVVPDGLPTISGDGGELVRLFQNLIANAIKYMPEGRQPRIEVLCRAQGAEWVVGVK
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCEEEEEC
DNGIGIPPDDLKRVFGIFQRLVAREQFEGTGIGLAVCRKIAEHHGGRIWVESEMGVGSTF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEE
LVAFPKA
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]