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The map label for this gene is mdtA [H]

Identifier: 83312535

GI number: 83312535

Start: 3766085

End: 3767377

Strand: Reverse

Name: mdtA [H]

Synonym: amb3436

Alternate gene names: 83312535

Gene position: 3767377-3766085 (Counterclockwise)

Preceding gene: 83312539

Following gene: 83312533

Centisome position: 75.85

GC content: 69.99

Gene sequence:

>1293_bases
GTGTTACCCTCTGTTACTGACAGGCCGGGGCGCTATGGTCATAATCCAGGCCGACGGAATTCCCAGGAGCGGGCCTTGCC
TTCCTTTGATCTCAAGAACCCTGTTTGGCGCAAGCGGGCGACCCTGGCCGGCGGTCTGGCGGCGGCGGCCGGTCTGGCGT
TCGCGCTGTGGCCCACGCCGCAGCCGGCTAAGACCGGCGGTCGGCCCGGCGGTCCCGACGGACGCCCGGTGGTGGTCACG
GTGACCAGCGTCGCCCGGCGCGACATGCCCATCTATCTCGACGCCATCGGCACGGTGCAGGCCTATAACACCGTCACGGT
GCGCTCGCGGGTCGACGGCGAACTGGTGGAGGTCCTGTTCAAGGAGGGCCAGGACGTTCATGCCGGCGACGTGCTGGCCC
AGATCGATCCCCGCACCTACCGCGCCCAATACGAGCAGGCCCTGGCCACCCGCGACAAGGACAGCGCCCAACTGGAGGCA
GCCAAGCGCGATCTGGCCCGCTATGTCAGCCTGGGCGACCGCGTCTCGGGCCAGAGCGTCGATACCCAGCGCGCCCTGGT
GCGCCAGCTGGAGGCCACGGTGCGGGCCGACGAGGCCTCGGCCTCCAATGCCAAGACCATGCTGTCCTATACGGTGATCG
CCGCGCCCATCGACGGGCGCACCGGCATGCGGCTGGTGGATCGCGGCAACATCGTGCGGGCGTCGGACGCCACCGGTCTG
GTGACGCTGACCCAGGTGCAGCCCATTTCGGTGGTCTTCACCCTGCCGCAGCAATCCCTGGCGGCGGTGAACGAGCAGTT
GCGCCTGGATGGCAAGCTCGCGGTTCAGGCCCTGCGGCCGGAAACCCGGGCGCTGGCCGACACGGGCGAGCTGGAACTGG
TGGACAACCAGATCGACCAGACCACCGGCACCATCAAGCTGAAGGCGGTGATGCCCAACGCCGAGCGCAAGCTGTGGCCG
GGCGGCTTCGTCAACGTGCGGCTGCTGCTGTCGACGCGCAAGGACGGGCTGGTGGTGCCGGCCCAGGCGGTGCAGCGCGG
CCCCCAGGGACCCTATGTCTTCGCCGTCAAGGAGGACCGCACCGTGGAGATGCGCGCGGTCAAGGTCGCCACCGTCGAGG
CGGGCCAGGCCCTGGTGGACGAAGGACTGGCCGAGGGTGACACCGTGGTGGTGGAGGGCACCGCCAAGCTGCAGCCCGGC
GCCCGCATCAGCACCGGCGACAAGGCCGGCGAGGGCCAGGGGCAAGGCCAGGGTCGCGGTGAGGGAAAGGGCCGCGCGGG
CAGGCCGCAATGA

Upstream 100 bases:

>100_bases
CCCCTTGCGAATGGGTAGTATCCTAGCGAGAGAATATGCATGAAGTATAAGTTTCTTATTAACCGAATGAAAATACCACA
GCAGCCCGGGGGCGAACACG

Downstream 100 bases:

>100_bases
CGCCCGGAATCCGGCCCAGAACGCATGACCCTGTCATCCTGACGACCAACGGGAGGAAGGATCTCGTCCTGGTCCGGCCC
GTCAGAATCGGCACCGTCCC

Product: membrane-fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MLPSVTDRPGRYGHNPGRRNSQERALPSFDLKNPVWRKRATLAGGLAAAAGLAFALWPTPQPAKTGGRPGGPDGRPVVVT
VTSVARRDMPIYLDAIGTVQAYNTVTVRSRVDGELVEVLFKEGQDVHAGDVLAQIDPRTYRAQYEQALATRDKDSAQLEA
AKRDLARYVSLGDRVSGQSVDTQRALVRQLEATVRADEASASNAKTMLSYTVIAAPIDGRTGMRLVDRGNIVRASDATGL
VTLTQVQPISVVFTLPQQSLAAVNEQLRLDGKLAVQALRPETRALADTGELELVDNQIDQTTGTIKLKAVMPNAERKLWP
GGFVNVRLLLSTRKDGLVVPAQAVQRGPQGPYVFAVKEDRTVEMRAVKVATVEAGQALVDEGLAEGDTVVVEGTAKLQPG
ARISTGDKAGEGQGQGQGRGEGKGRAGRPQ

Sequences:

>Translated_430_residues
MLPSVTDRPGRYGHNPGRRNSQERALPSFDLKNPVWRKRATLAGGLAAAAGLAFALWPTPQPAKTGGRPGGPDGRPVVVT
VTSVARRDMPIYLDAIGTVQAYNTVTVRSRVDGELVEVLFKEGQDVHAGDVLAQIDPRTYRAQYEQALATRDKDSAQLEA
AKRDLARYVSLGDRVSGQSVDTQRALVRQLEATVRADEASASNAKTMLSYTVIAAPIDGRTGMRLVDRGNIVRASDATGL
VTLTQVQPISVVFTLPQQSLAAVNEQLRLDGKLAVQALRPETRALADTGELELVDNQIDQTTGTIKLKAVMPNAERKLWP
GGFVNVRLLLSTRKDGLVVPAQAVQRGPQGPYVFAVKEDRTVEMRAVKVATVEAGQALVDEGLAEGDTVVVEGTAKLQPG
ARISTGDKAGEGQGQGQGRGEGKGRAGRPQ
>Mature_430_residues
MLPSVTDRPGRYGHNPGRRNSQERALPSFDLKNPVWRKRATLAGGLAAAAGLAFALWPTPQPAKTGGRPGGPDGRPVVVT
VTSVARRDMPIYLDAIGTVQAYNTVTVRSRVDGELVEVLFKEGQDVHAGDVLAQIDPRTYRAQYEQALATRDKDSAQLEA
AKRDLARYVSLGDRVSGQSVDTQRALVRQLEATVRADEASASNAKTMLSYTVIAAPIDGRTGMRLVDRGNIVRASDATGL
VTLTQVQPISVVFTLPQQSLAAVNEQLRLDGKLAVQALRPETRALADTGELELVDNQIDQTTGTIKLKAVMPNAERKLWP
GGFVNVRLLLSTRKDGLVVPAQAVQRGPQGPYVFAVKEDRTVEMRAVKVATVEAGQALVDEGLAEGDTVVVEGTAKLQPG
ARISTGDKAGEGQGQGQGRGEGKGRAGRPQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=346, Percent_Identity=41.0404624277457, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1786668, Length=334, Percent_Identity=34.4311377245509, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789665, Length=335, Percent_Identity=32.8358208955224, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789929, Length=310, Percent_Identity=30, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45902; Mature: 45902

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSVTDRPGRYGHNPGRRNSQERALPSFDLKNPVWRKRATLAGGLAAAAGLAFALWPTP
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCC
QPAKTGGRPGGPDGRPVVVTVTSVARRDMPIYLDAIGTVQAYNTVTVRSRVDGELVEVLF
CCCCCCCCCCCCCCCEEEEEEEHHHHCCCCEEEEECCCEEECEEEEEECCCCHHHHHHHH
KEGQDVHAGDVLAQIDPRTYRAQYEQALATRDKDSAQLEAAKRDLARYVSLGDRVSGQSV
HCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
DTQRALVRQLEATVRADEASASNAKTMLSYTVIAAPIDGRTGMRLVDRGNIVRASDATGL
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEECCCEEEECCCCCE
VTLTQVQPISVVFTLPQQSLAAVNEQLRLDGKLAVQALRPETRALADTGELELVDNQIDQ
EEEEEECEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCEEEECCHHCC
TTGTIKLKAVMPNAERKLWPGGFVNVRLLLSTRKDGLVVPAQAVQRGPQGPYVFAVKEDR
CCCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCEEECHHHHHCCCCCCEEEEEECCC
TVEMRAVKVATVEAGQALVDEGLAEGDTVVVEGTAKLQPGARISTGDKAGEGQGQGQGRG
EEEEEEEEEEEECCCHHHHHCCCCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCC
EGKGRAGRPQ
CCCCCCCCCC
>Mature Secondary Structure
MLPSVTDRPGRYGHNPGRRNSQERALPSFDLKNPVWRKRATLAGGLAAAAGLAFALWPTP
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCC
QPAKTGGRPGGPDGRPVVVTVTSVARRDMPIYLDAIGTVQAYNTVTVRSRVDGELVEVLF
CCCCCCCCCCCCCCCEEEEEEEHHHHCCCCEEEEECCCEEECEEEEEECCCCHHHHHHHH
KEGQDVHAGDVLAQIDPRTYRAQYEQALATRDKDSAQLEAAKRDLARYVSLGDRVSGQSV
HCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
DTQRALVRQLEATVRADEASASNAKTMLSYTVIAAPIDGRTGMRLVDRGNIVRASDATGL
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEECCCEEEECCCCCE
VTLTQVQPISVVFTLPQQSLAAVNEQLRLDGKLAVQALRPETRALADTGELELVDNQIDQ
EEEEEECEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCEEEECCHHCC
TTGTIKLKAVMPNAERKLWPGGFVNVRLLLSTRKDGLVVPAQAVQRGPQGPYVFAVKEDR
CCCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCEEECHHHHHCCCCCCEEEEEECCC
TVEMRAVKVATVEAGQALVDEGLAEGDTVVVEGTAKLQPGARISTGDKAGEGQGQGQGRG
EEEEEEEEEEEECCCHHHHHCCCCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCC
EGKGRAGRPQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA