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The map label for this gene is iscR [H]

Identifier: 83312129

GI number: 83312129

Start: 3272507

End: 3272980

Strand: Reverse

Name: iscR [H]

Synonym: amb3030

Alternate gene names: 83312129

Gene position: 3272980-3272507 (Counterclockwise)

Preceding gene: 83312130

Following gene: 83312128

Centisome position: 65.89

GC content: 63.92

Gene sequence:

>474_bases
GTGAAACTCAGCACCAAAGGACGCTACGCCGTCATGGCCATGGTCGATCTGGCCAGCCACTCCGAGGGAAGCCCGGTGGC
CCTGGCCGATATCGCCGAGCGCCAGGAGATTTCGCTCTCCTATCTCGAACAGCTGTTCGGCAAGCTTCGGAAGGGCGGGC
TGGTCAAGAGCGTGCGCGGTCCGGGCGGCGGCTATCTTTTGTCGCGAATCCCACAACAGACGCGCATATCCGACATTATC
CTGGCGGTGGACGAGCCGATCCAGACCACGCGCTGCTCGCCGGGCTCGCCGGCCGGCTGTCACAACAACAAGGGCCGCTG
CCTGACCCACGATCTGTGGGAAGAGCTGGGCAACCAGATTTACCTCTATCTCAGCTCGGTTTCCCTGGCCGATGTGTGCG
AACGCCGCATCCTGGGCAGCTCGGGCATGTTCCACGGCACCGCCGCTCCCTCTGGAGCCGTGGCGGCGCAATAA

Upstream 100 bases:

>100_bases
CTGAAGGGGCTGAACCGGGCGACAAGACCAAGCAAGTTGAAGCAGTAACCATGCCGGCCGGCGGGACAACAGGCCGGACT
CTGGAACGGGAGACCATATC

Downstream 100 bases:

>100_bases
GGGTCGGGAAAGGAAGGAACAGCGTGAGCAGGGCCGTCTACCTCGATTACAACTCCGGCGCCCCCGTGCGCCCCGAGGTG
GCGGCCGCCATGGTGGAGTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKLSTKGRYAVMAMVDLASHSEGSPVALADIAERQEISLSYLEQLFGKLRKGGLVKSVRGPGGGYLLSRIPQQTRISDII
LAVDEPIQTTRCSPGSPAGCHNNKGRCLTHDLWEELGNQIYLYLSSVSLADVCERRILGSSGMFHGTAAPSGAVAAQ

Sequences:

>Translated_157_residues
MKLSTKGRYAVMAMVDLASHSEGSPVALADIAERQEISLSYLEQLFGKLRKGGLVKSVRGPGGGYLLSRIPQQTRISDII
LAVDEPIQTTRCSPGSPAGCHNNKGRCLTHDLWEELGNQIYLYLSSVSLADVCERRILGSSGMFHGTAAPSGAVAAQ
>Mature_157_residues
MKLSTKGRYAVMAMVDLASHSEGSPVALADIAERQEISLSYLEQLFGKLRKGGLVKSVRGPGGGYLLSRIPQQTRISDII
LAVDEPIQTTRCSPGSPAGCHNNKGRCLTHDLWEELGNQIYLYLSSVSLADVCERRILGSSGMFHGTAAPSGAVAAQ

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=151, Percent_Identity=49.0066225165563, Blast_Score=137, Evalue=2e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16773; Mature: 16773

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTKGRYAVMAMVDLASHSEGSPVALADIAERQEISLSYLEQLFGKLRKGGLVKSVRG
CCCCCCCCEEEHEEHHHHCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCC
PGGGYLLSRIPQQTRISDIILAVDEPIQTTRCSPGSPAGCHNNKGRCLTHDLWEELGNQI
CCCCHHHHHCCCHHHHHHEEEECCCCCHHCCCCCCCCCCCCCCCCCEECHHHHHHHCCEE
YLYLSSVSLADVCERRILGSSGMFHGTAAPSGAVAAQ
EEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLSTKGRYAVMAMVDLASHSEGSPVALADIAERQEISLSYLEQLFGKLRKGGLVKSVRG
CCCCCCCCEEEHEEHHHHCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCC
PGGGYLLSRIPQQTRISDIILAVDEPIQTTRCSPGSPAGCHNNKGRCLTHDLWEELGNQI
CCCCHHHHHCCCHHHHHHEEEECCCCCHHCCCCCCCCCCCCCCCCCEECHHHHHHHCCEE
YLYLSSVSLADVCERRILGSSGMFHGTAAPSGAVAAQ
EEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]