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The map label for this gene is resA [H]

Identifier: 83312013

GI number: 83312013

Start: 3110318

End: 3110806

Strand: Reverse

Name: resA [H]

Synonym: amb2914

Alternate gene names: 83312013

Gene position: 3110806-3110318 (Counterclockwise)

Preceding gene: 83312014

Following gene: 83312012

Centisome position: 62.63

GC content: 66.26

Gene sequence:

>489_bases
ATGAGAGCGTTCCGTCTGTTGGCCGTCCTGCTGCTGTTGGCTGGGTGCGGCGAGGAGGGGGGCAAGGCCCCCCATGTGGG
CGATGCGCCGCCCGCCTTTAAGCTGAGCGCCCTGGACGGGGCGGTGGTGGATTATCCCGCCCAACTGTCCGGCAAGGTGG
TGGTGGTGCGGTTCTGGGCGACGTGGTGCCCATTCTGTAAGGACGAAATGAAGATGATCCAGGCCGTGTGGAGCCAGTCC
CGCGACAGGGGCTTCGAGGTTCTGGCGGTCAATGCCGGCCAGGACAAGGGCGACATCGACGGATTCGTCGCCAAGCTGGG
CGTGACCTATCCGGTGCTGCTGGACCCCGGCTCCAAGGTCACCCGGCAATACGGCGTCACCGGCCTGCCCATGACCCTGT
TCGTCGGCCGCGACGGCAGGATCAAAGGCCGCATCCTGGGCGAGACCGACGAGGCCACCTTCCGCCGCAAGCTGGAGGAG
CTGCTATGA

Upstream 100 bases:

>100_bases
TCGGCCTGTTCGGCGCGGTGACGCTGTGGCTGATCTGGCGCTCGCACCTGATCTTGCTGGAGCCCGAGCGGCTTTTGCCC
ATCCTGCCCGGAGGCCAACC

Downstream 100 bases:

>100_bases
ACAATACGCCGGAGCAGAGCTGCGACCTTTGCGGTCTGCCGGTGCTCAAGGACGGCCTACACTTGAAGGCCTCTGGGCGG
GAATACGCCTTTTGCTGCGA

Product: Thiol-disulfide isomerase and thioredoxins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRAFRLLAVLLLLAGCGEEGGKAPHVGDAPPAFKLSALDGAVVDYPAQLSGKVVVVRFWATWCPFCKDEMKMIQAVWSQS
RDRGFEVLAVNAGQDKGDIDGFVAKLGVTYPVLLDPGSKVTRQYGVTGLPMTLFVGRDGRIKGRILGETDEATFRRKLEE
LL

Sequences:

>Translated_162_residues
MRAFRLLAVLLLLAGCGEEGGKAPHVGDAPPAFKLSALDGAVVDYPAQLSGKVVVVRFWATWCPFCKDEMKMIQAVWSQS
RDRGFEVLAVNAGQDKGDIDGFVAKLGVTYPVLLDPGSKVTRQYGVTGLPMTLFVGRDGRIKGRILGETDEATFRRKLEE
LL
>Mature_162_residues
MRAFRLLAVLLLLAGCGEEGGKAPHVGDAPPAFKLSALDGAVVDYPAQLSGKVVVVRFWATWCPFCKDEMKMIQAVWSQS
RDRGFEVLAVNAGQDKGDIDGFVAKLGVTYPVLLDPGSKVTRQYGVTGLPMTLFVGRDGRIKGRILGETDEATFRRKLEE
LL

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=139, Percent_Identity=28.0575539568345, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 17627; Mature: 17627

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFRLLAVLLLLAGCGEEGGKAPHVGDAPPAFKLSALDGAVVDYPAQLSGKVVVVRFWA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCCCEEEEEEHH
TWCPFCKDEMKMIQAVWSQSRDRGFEVLAVNAGQDKGDIDGFVAKLGVTYPVLLDPGSKV
HHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHH
TRQYGVTGLPMTLFVGRDGRIKGRILGETDEATFRRKLEELL
HHHHCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHC
>Mature Secondary Structure
MRAFRLLAVLLLLAGCGEEGGKAPHVGDAPPAFKLSALDGAVVDYPAQLSGKVVVVRFWA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCCCEEEEEEHH
TWCPFCKDEMKMIQAVWSQSRDRGFEVLAVNAGQDKGDIDGFVAKLGVTYPVLLDPGSKV
HHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHH
TRQYGVTGLPMTLFVGRDGRIKGRILGETDEATFRRKLEELL
HHHHCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA