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The map label for this gene is nuoL [H]

Identifier: 83311875

GI number: 83311875

Start: 2962483

End: 2964411

Strand: Reverse

Name: nuoL [H]

Synonym: amb2776

Alternate gene names: 83311875

Gene position: 2964411-2962483 (Counterclockwise)

Preceding gene: 83311876

Following gene: 83311874

Centisome position: 59.68

GC content: 65.99

Gene sequence:

>1929_bases
ATGATCACTGCAACCGTATTCCTGCCGCTCCTTGGCGCCGTCGTCGCAGGCCTGTTCGGCCGCTTCATTGGTGATCGCGG
CGCGCAGATCGTCACCTGCGCCCTGCTGATCACCTCGGCGGTCCTGTCGGGGCTGATCTTCCAGAAGGTCGCCTTGGGGG
GCGAGGCCCAGACCGTGGTGGTCGCCGAGTGGATCCGTTCGGGCACCATGTCGGTGAACTGGTCGCTGAAGGTCGATACC
CTGACCGCCGTCATGCTGATCGTCGTCACCTGGGTGTCGGCGGCCGTGCACGTCTATTCGGTCGGCTATATGAGCCACGA
CCCCTCCATCTGGCGCTTCCACAGCTATCTGTCGCTGTTCACCTTCGCCATGCTGATGCTGGTGACCTCGGACAATCTGG
TGCAGATGTTCTTCGGCTGGGAGGGCGTCGGTGTCGCCTCCTACCTGCTGATCGGCTTCTGGTACGAGAAGCCCTCGGCC
TCGGCCGCCGCCATCAAGGCCTTCGTAGTCAACCGCGTCGGCGATTTCGGCTTCGCGCTGGGCATCTTCGGCGTGTATTT
CCTGTTCGGCTCTGTGGGCTTCGACGCCATCTTCGCCGCCGCGCCGGAAAAGGCCAACGCCACCGTGAACTTCTTCGGCG
GCCAGTGGCACGCCATCACCATCTGCTGCCTGCTGCTGTTCGTGGGCGCCATGGGCAAGTCGGCCCAGCTGGGCCTGCAT
ACCTGGCTGCCCGACGCCATGGAGGGCCCGACCCCGGTCTCCGCCCTGATCCATGCCGCCACCATGGTCACCGCCGGCGT
CTTCATGGTCGCCCGCATGAGCCCCCTGTTCGAATTCTCGGACACCGCGCTCACCGTGGTGACCGTGATCGGCGCCGCCA
CCGCCATCTTCGCGGCGACGGTGGGCTGCGTGCAGAACGACATAAAGCGGGTGATCGCCTATTCCACCTGCTCGCAGCTG
GGCTACATGTTCTTCGCCATCGGCGTGTCGGCCTATCAGGCCGCCATCTTCCACCTGATGACCCACGCCTTCTTCAAGGC
CCTGCTGTTCCTGGGCGCCGGCTCGGTGATCCACGCCATGAGCGACGAGCAGGACATCCGCCGCATGGGCGGCATCTGGA
AGCATGTCAAGGTCACCTGGGTGCTGATGTGGATCGGGTCGCTGGCCCTGGCCGGCGTGCCGTTCTTCGCCGGCTACTAT
TCCAAGGACACCATCCTGGAAGCCGCCTGGGCGTCGCACACCATCGCGGGGCAGGGGGCTTATTGGCTGGGCTGCACCGC
GGCCTTCCTGACCGCCTTCTACTCCTGGCGCCTGCTGCTGCTGACCTTCCACGGCCGTCCGCGCGCGGACGAGCATGTGA
TGGCCCATGTGCATGAGAGCCCGGCGGTGATGCTGATTCCGCTGCTGTTCCTGGCCACCGGCGCCCTGTTCGCCGGCTGG
GCGGGCTACGACATGTTCGTCGGCCATCACCAGCACGACTTCTGGCGCTCCGCCATCCTGGTGACCGAGGCTCATCCCTC
GCTGGAGAATGCCCATCACGTGCCGTCCTGGGTGGCCCTGCTGCCCACCGTGGTGGCGGTGTCGGGCATCGCCCTGGCCT
ATTTGTTCTACGTGTTCGCTCCGGGGCTACCCGGGGCACTGGCCGGCGCCTTCCGCGGCGTCCACCAGTTCCTGCTGAAC
AAGTGGTACTTCGACGAGCTGTACGACATGCTGTTCGTGAAGCCCGCCTTCAAGCTCGGCCGCGGTCTGTGGCAGGGTGG
CGACGGCGCGCTGATCGACGGCGTGGGTCCGGACGGCGTGGCGGCGGCGACCCGTGCGGTGGCGGCCAAGGTGGCTCGCG
CCCAGAGCGGCTACCTCTACCACTACGCCTACGCCATGCTGATCGGGGTGGCGGCCTTCGTCACCTGGTACATTTTCAAC
GCGCGCTGA

Upstream 100 bases:

>100_bases
GCGGCGGAAGCCGCCATCGGCCTGGCCATCGTCGTTGTCTTCTTCCGTAACCGCGGCACCATCGCGGTGGAAGAAATCAG
CCAGCTCAAGGGGTAAGCGG

Downstream 100 bases:

>100_bases
GGACGAGGAAGACGCCCCATGAACGACTGGCCCCTTCTCTCGCTGACCACGTTCCTGCCCCTGGCCGGAGCGCTGTTCAT
CCTCACCATCCGCGGCGAGA

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MITATVFLPLLGAVVAGLFGRFIGDRGAQIVTCALLITSAVLSGLIFQKVALGGEAQTVVVAEWIRSGTMSVNWSLKVDT
LTAVMLIVVTWVSAAVHVYSVGYMSHDPSIWRFHSYLSLFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFWYEKPSA
SAAAIKAFVVNRVGDFGFALGIFGVYFLFGSVGFDAIFAAAPEKANATVNFFGGQWHAITICCLLLFVGAMGKSAQLGLH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFEFSDTALTVVTVIGAATAIFAATVGCVQNDIKRVIAYSTCSQL
GYMFFAIGVSAYQAAIFHLMTHAFFKALLFLGAGSVIHAMSDEQDIRRMGGIWKHVKVTWVLMWIGSLALAGVPFFAGYY
SKDTILEAAWASHTIAGQGAYWLGCTAAFLTAFYSWRLLLLTFHGRPRADEHVMAHVHESPAVMLIPLLFLATGALFAGW
AGYDMFVGHHQHDFWRSAILVTEAHPSLENAHHVPSWVALLPTVVAVSGIALAYLFYVFAPGLPGALAGAFRGVHQFLLN
KWYFDELYDMLFVKPAFKLGRGLWQGGDGALIDGVGPDGVAAATRAVAAKVARAQSGYLYHYAYAMLIGVAAFVTWYIFN
AR

Sequences:

>Translated_642_residues
MITATVFLPLLGAVVAGLFGRFIGDRGAQIVTCALLITSAVLSGLIFQKVALGGEAQTVVVAEWIRSGTMSVNWSLKVDT
LTAVMLIVVTWVSAAVHVYSVGYMSHDPSIWRFHSYLSLFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFWYEKPSA
SAAAIKAFVVNRVGDFGFALGIFGVYFLFGSVGFDAIFAAAPEKANATVNFFGGQWHAITICCLLLFVGAMGKSAQLGLH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFEFSDTALTVVTVIGAATAIFAATVGCVQNDIKRVIAYSTCSQL
GYMFFAIGVSAYQAAIFHLMTHAFFKALLFLGAGSVIHAMSDEQDIRRMGGIWKHVKVTWVLMWIGSLALAGVPFFAGYY
SKDTILEAAWASHTIAGQGAYWLGCTAAFLTAFYSWRLLLLTFHGRPRADEHVMAHVHESPAVMLIPLLFLATGALFAGW
AGYDMFVGHHQHDFWRSAILVTEAHPSLENAHHVPSWVALLPTVVAVSGIALAYLFYVFAPGLPGALAGAFRGVHQFLLN
KWYFDELYDMLFVKPAFKLGRGLWQGGDGALIDGVGPDGVAAATRAVAAKVARAQSGYLYHYAYAMLIGVAAFVTWYIFN
AR
>Mature_642_residues
MITATVFLPLLGAVVAGLFGRFIGDRGAQIVTCALLITSAVLSGLIFQKVALGGEAQTVVVAEWIRSGTMSVNWSLKVDT
LTAVMLIVVTWVSAAVHVYSVGYMSHDPSIWRFHSYLSLFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFWYEKPSA
SAAAIKAFVVNRVGDFGFALGIFGVYFLFGSVGFDAIFAAAPEKANATVNFFGGQWHAITICCLLLFVGAMGKSAQLGLH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFEFSDTALTVVTVIGAATAIFAATVGCVQNDIKRVIAYSTCSQL
GYMFFAIGVSAYQAAIFHLMTHAFFKALLFLGAGSVIHAMSDEQDIRRMGGIWKHVKVTWVLMWIGSLALAGVPFFAGYY
SKDTILEAAWASHTIAGQGAYWLGCTAAFLTAFYSWRLLLLTFHGRPRADEHVMAHVHESPAVMLIPLLFLATGALFAGW
AGYDMFVGHHQHDFWRSAILVTEAHPSLENAHHVPSWVALLPTVVAVSGIALAYLFYVFAPGLPGALAGAFRGVHQFLLN
KWYFDELYDMLFVKPAFKLGRGLWQGGDGALIDGVGPDGVAAATRAVAAKVARAQSGYLYHYAYAMLIGVAAFVTWYIFN
AR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=432, Percent_Identity=43.287037037037, Blast_Score=335, Evalue=1e-91,
Organism=Escherichia coli, GI1788614, Length=642, Percent_Identity=38.9408099688474, Blast_Score=352, Evalue=5e-98,
Organism=Escherichia coli, GI1788829, Length=351, Percent_Identity=31.3390313390313, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1788831, Length=358, Percent_Identity=28.4916201117318, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1788827, Length=429, Percent_Identity=25.1748251748252, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI145693160, Length=363, Percent_Identity=22.3140495867769, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788613, Length=264, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367154, Length=213, Percent_Identity=27.6995305164319, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 69413; Mature: 69413

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITATVFLPLLGAVVAGLFGRFIGDRGAQIVTCALLITSAVLSGLIFQKVALGGEAQTVV
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VAEWIRSGTMSVNWSLKVDTLTAVMLIVVTWVSAAVHVYSVGYMSHDPSIWRFHSYLSLF
HHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
TFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFWYEKPSASAAAIKAFVVNRVGDFGFAL
HHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GIFGVYFLFGSVGFDAIFAAAPEKANATVNFFGGQWHAITICCLLLFVGAMGKSAQLGLH
HHHHHHHHHHHHCHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFEFSDTALTVVTVIGAATAIFAAT
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHH
VGCVQNDIKRVIAYSTCSQLGYMFFAIGVSAYQAAIFHLMTHAFFKALLFLGAGSVIHAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
SDEQDIRRMGGIWKHVKVTWVLMWIGSLALAGVPFFAGYYSKDTILEAAWASHTIAGQGA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCC
YWLGCTAAFLTAFYSWRLLLLTFHGRPRADEHVMAHVHESPAVMLIPLLFLATGALFAGW
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
AGYDMFVGHHQHDFWRSAILVTEAHPSLENAHHVPSWVALLPTVVAVSGIALAYLFYVFA
CCHHHHHCCCCHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PGLPGALAGAFRGVHQFLLNKWYFDELYDMLFVKPAFKLGRGLWQGGDGALIDGVGPDGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCHH
AAATRAVAAKVARAQSGYLYHYAYAMLIGVAAFVTWYIFNAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITATVFLPLLGAVVAGLFGRFIGDRGAQIVTCALLITSAVLSGLIFQKVALGGEAQTVV
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VAEWIRSGTMSVNWSLKVDTLTAVMLIVVTWVSAAVHVYSVGYMSHDPSIWRFHSYLSLF
HHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
TFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFWYEKPSASAAAIKAFVVNRVGDFGFAL
HHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GIFGVYFLFGSVGFDAIFAAAPEKANATVNFFGGQWHAITICCLLLFVGAMGKSAQLGLH
HHHHHHHHHHHHCHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFEFSDTALTVVTVIGAATAIFAAT
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHH
VGCVQNDIKRVIAYSTCSQLGYMFFAIGVSAYQAAIFHLMTHAFFKALLFLGAGSVIHAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
SDEQDIRRMGGIWKHVKVTWVLMWIGSLALAGVPFFAGYYSKDTILEAAWASHTIAGQGA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCC
YWLGCTAAFLTAFYSWRLLLLTFHGRPRADEHVMAHVHESPAVMLIPLLFLATGALFAGW
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
AGYDMFVGHHQHDFWRSAILVTEAHPSLENAHHVPSWVALLPTVVAVSGIALAYLFYVFA
CCHHHHHCCCCHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PGLPGALAGAFRGVHQFLLNKWYFDELYDMLFVKPAFKLGRGLWQGGDGALIDGVGPDGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCHH
AAATRAVAAKVARAQSGYLYHYAYAMLIGVAAFVTWYIFNAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]