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The map label for this gene is aphA [H]

Identifier: 83311835

GI number: 83311835

Start: 2921806

End: 2923956

Strand: Reverse

Name: aphA [H]

Synonym: amb2736

Alternate gene names: 83311835

Gene position: 2923956-2921806 (Counterclockwise)

Preceding gene: 83311837

Following gene: 83311832

Centisome position: 58.87

GC content: 64.39

Gene sequence:

>2151_bases
GTGGTTTCCCCATCAGGCCAAAGCTGTAAAATCGGGAGAATGAAAGCAGCGGGGCGAAACATGGATGCCGTTAGGCCGGC
GGGTCTCGGCGAGTCCGACGAGTCCGAGGCATTGGGATTCCGCCGGTTGCGCCGGTGGCTGGTTGCGGGTTTCGTGGCCG
CCAACCTGTTTTTCGCCATCGCCTACCTGGTCATGGTGTGGCTGGGGCCGCGCTACGCCCTGGAGGAGGCCGGACGCTCC
ACGAGCACCCTGGCCCTGGCGCTGTCCGAGCAGGTGGAGGCGACTATTCGCTCCGAGGCCGCCATCCTGACCTCGCTGCA
GCGCGAGATCCGGAGCCGGGGCGGCGTGGCGGCCTTCGATGAAACCGCGTGGTACCAGATGTTCATGGCTCATCTGGACC
TTTTCAGCGACGATCCCGCCGACAAGCCCATGCACGCCCTGTTCTTCGTGGATTCCACTGGCATCGCCTCGGCCAGTTCG
GTCAGCAACCCTACCCGGCAGGCCGACGCCTCCATGCGGCCGTATTTCATCTTTCACCGCGATCATCCCGGCGACGAACT
GCATATCTCCGAGATTTCCCAGTCCAAGATCACCGGATTGTGGGTTTTCTTTCTGACCCAGAGGATCAACGGGCCGGATG
GTTCGTTTCAGGGCGTGCTCGGCATGTCGCTGCGCATCAACCGGTTCGAGGAGCTGTTCGCCCATCTTCGCCTGCCCGCC
GACGGGTCCATCGTCATCCAGCGTCTGGACGGGGCGCCCTTGTTCCGCCACCCCTTCACCGAGGCCTTCGCCACCTCCCA
GCCGGGCAGCCTTCCCCGCGTGGCCGGCATGGTGGCCAAGGGGGCGGGCGCCCACGAGCAGGTCAGCCCCTTCGACGGTA
AGACCCGCATCATCGGCTATAACGTCGGACGGCATTATCCCATCCTGGCCTCGGCCACGGTGACGCGCGAGGGCGCGCTG
GCCGGCTGGTACCGCACCTTGTCGTGGTTCACCGGGCTGGGGCTGGCCGCTCTGGGCTTGGGCGCGATACTGTTCATATT
CGCGCTGAAGCATTTGGGAAGCCTGGAGCGCGAGGCCCGCATGCGGCGCCTGTCCCAGACCGTCGACCAAAATCCCAACA
TGATCCTCACCACGGATTCCCGGGGGGTGATCGACTACGCCAATTCCAGCTTCTACCGTTTCACCGGCTTTGAGCCCGAC
CAGGTGATCGGCGCCACGCCGCGCATTCTCAAGTCCGACGAGACGCCGCCCGAGGTCTTCGTCGATCTGTGGCAGACCAT
CCGGGCGGGGCGGGAATGGCGTGGCGAGTTGGTCAATCGTCGCAGGGACGGCCAAACCTATTGGGCATCCGTGGTCATCT
CGCCGGTGCTCGACGAGGAAAGCGGGCTCTGCGGCTTCGTCGGCATGCAGGAGGATATCAGCGAGCGCAAGCGCATCGAA
GGGCGGGTGGCGGAATTGGTCGCCGAGCTCAAGCGATCCAACGAGGAGCTTGAGAATTTCGCCTACGTTGCCTCTCACGA
CCTGCGCCAGCCGCTGCGCATGATCAATTCCTATCTCGGCCTGCTGCGCAAGCGGCTGGCCGCCTCCTTCGACCAGGAAG
CCGAAGAGTTCTTCGCCTTTGCCTCTGACGGCGCCAGACGTCTGGACCTCATGATTGTCGACCTGCTGGAGTTTTCGCGC
ATCGGCAAGCAATCGACCCGGGAGATGCTCGACCTCAATGGGGTGGTGGCCGACGGGATGCAGAATCTTGCCGTGGCCAT
CCGCGATTGTGGGGCGGAGATCAGCGTGGCCCCCGGCCTGCCGACCATTCCGGGAGACCGGTCCGAGCTGACCCGCCTGT
TCCAGAACCTGATCGGCAACGCCCTGAAATACTGCCCCGAGGAGCGCAAGCCGGTGGTGGACATCTCGTGCCGCGATGGC
GGGCGGGAATGGATCCTTTCCGTCAGGGACAACGGCATCGGCATCGAGGCGGAGTGCCTGGAGAAGGTCTTCGGAATCTT
CCAGCGCATGGTCAGCCGCGACAAGTATGAAGGCACCGGCATCGGTCTTGCGGTGTGCCGCAAGATCGCCGAGCACCACG
GCGGCCGCATCTGGGTCGAGTCCGTGGTTGACCACGGCTCGACCTTCCACGTCGCCCTTCCCAAGGCATGA

Upstream 100 bases:

>100_bases
GCGGGGATGTAGCAATAATTTCGATTCCGATCATCTGCAATCTGGCGCAGGGGAAGTTTCCATGAAATTTATAGTTCATT
GGTAATATCTGGTGGATCAG

Downstream 100 bases:

>100_bases
TCAGACGCATTTGCGGATATAGGGCTTGTTGATCTCCCACAATTCGTCCAACAGCTTGACCGCGGCGTCCGAGGAATTGA
CCACAGGATCGGCCAGCAGC

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MVSPSGQSCKIGRMKAAGRNMDAVRPAGLGESDESEALGFRRLRRWLVAGFVAANLFFAIAYLVMVWLGPRYALEEAGRS
TSTLALALSEQVEATIRSEAAILTSLQREIRSRGGVAAFDETAWYQMFMAHLDLFSDDPADKPMHALFFVDSTGIASASS
VSNPTRQADASMRPYFIFHRDHPGDELHISEISQSKITGLWVFFLTQRINGPDGSFQGVLGMSLRINRFEELFAHLRLPA
DGSIVIQRLDGAPLFRHPFTEAFATSQPGSLPRVAGMVAKGAGAHEQVSPFDGKTRIIGYNVGRHYPILASATVTREGAL
AGWYRTLSWFTGLGLAALGLGAILFIFALKHLGSLEREARMRRLSQTVDQNPNMILTTDSRGVIDYANSSFYRFTGFEPD
QVIGATPRILKSDETPPEVFVDLWQTIRAGREWRGELVNRRRDGQTYWASVVISPVLDEESGLCGFVGMQEDISERKRIE
GRVAELVAELKRSNEELENFAYVASHDLRQPLRMINSYLGLLRKRLAASFDQEAEEFFAFASDGARRLDLMIVDLLEFSR
IGKQSTREMLDLNGVVADGMQNLAVAIRDCGAEISVAPGLPTIPGDRSELTRLFQNLIGNALKYCPEERKPVVDISCRDG
GREWILSVRDNGIGIEAECLEKVFGIFQRMVSRDKYEGTGIGLAVCRKIAEHHGGRIWVESVVDHGSTFHVALPKA

Sequences:

>Translated_716_residues
MVSPSGQSCKIGRMKAAGRNMDAVRPAGLGESDESEALGFRRLRRWLVAGFVAANLFFAIAYLVMVWLGPRYALEEAGRS
TSTLALALSEQVEATIRSEAAILTSLQREIRSRGGVAAFDETAWYQMFMAHLDLFSDDPADKPMHALFFVDSTGIASASS
VSNPTRQADASMRPYFIFHRDHPGDELHISEISQSKITGLWVFFLTQRINGPDGSFQGVLGMSLRINRFEELFAHLRLPA
DGSIVIQRLDGAPLFRHPFTEAFATSQPGSLPRVAGMVAKGAGAHEQVSPFDGKTRIIGYNVGRHYPILASATVTREGAL
AGWYRTLSWFTGLGLAALGLGAILFIFALKHLGSLEREARMRRLSQTVDQNPNMILTTDSRGVIDYANSSFYRFTGFEPD
QVIGATPRILKSDETPPEVFVDLWQTIRAGREWRGELVNRRRDGQTYWASVVISPVLDEESGLCGFVGMQEDISERKRIE
GRVAELVAELKRSNEELENFAYVASHDLRQPLRMINSYLGLLRKRLAASFDQEAEEFFAFASDGARRLDLMIVDLLEFSR
IGKQSTREMLDLNGVVADGMQNLAVAIRDCGAEISVAPGLPTIPGDRSELTRLFQNLIGNALKYCPEERKPVVDISCRDG
GREWILSVRDNGIGIEAECLEKVFGIFQRMVSRDKYEGTGIGLAVCRKIAEHHGGRIWVESVVDHGSTFHVALPKA
>Mature_716_residues
MVSPSGQSCKIGRMKAAGRNMDAVRPAGLGESDESEALGFRRLRRWLVAGFVAANLFFAIAYLVMVWLGPRYALEEAGRS
TSTLALALSEQVEATIRSEAAILTSLQREIRSRGGVAAFDETAWYQMFMAHLDLFSDDPADKPMHALFFVDSTGIASASS
VSNPTRQADASMRPYFIFHRDHPGDELHISEISQSKITGLWVFFLTQRINGPDGSFQGVLGMSLRINRFEELFAHLRLPA
DGSIVIQRLDGAPLFRHPFTEAFATSQPGSLPRVAGMVAKGAGAHEQVSPFDGKTRIIGYNVGRHYPILASATVTREGAL
AGWYRTLSWFTGLGLAALGLGAILFIFALKHLGSLEREARMRRLSQTVDQNPNMILTTDSRGVIDYANSSFYRFTGFEPD
QVIGATPRILKSDETPPEVFVDLWQTIRAGREWRGELVNRRRDGQTYWASVVISPVLDEESGLCGFVGMQEDISERKRIE
GRVAELVAELKRSNEELENFAYVASHDLRQPLRMINSYLGLLRKRLAASFDQEAEEFFAFASDGARRLDLMIVDLLEFSR
IGKQSTREMLDLNGVVADGMQNLAVAIRDCGAEISVAPGLPTIPGDRSELTRLFQNLIGNALKYCPEERKPVVDISCRDG
GREWILSVRDNGIGIEAECLEKVFGIFQRMVSRDKYEGTGIGLAVCRKIAEHHGGRIWVESVVDHGSTFHVALPKA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=378, Percent_Identity=26.4550264550265, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1788549, Length=346, Percent_Identity=25.7225433526012, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=280, Percent_Identity=28.9285714285714, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786912, Length=288, Percent_Identity=26.7361111111111, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=29.5964125560538, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=377, Percent_Identity=22.2811671087533, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=27.34375, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=27.2300469483568, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79286; Mature: 79286

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPSGQSCKIGRMKAAGRNMDAVRPAGLGESDESEALGFRRLRRWLVAGFVAANLFFAI
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLVMVWLGPRYALEEAGRSTSTLALALSEQVEATIRSEAAILTSLQREIRSRGGVAAFD
HHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
ETAWYQMFMAHLDLFSDDPADKPMHALFFVDSTGIASASSVSNPTRQADASMRPYFIFHR
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEEC
DHPGDELHISEISQSKITGLWVFFLTQRINGPDGSFQGVLGMSLRINRFEELFAHLRLPA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DGSIVIQRLDGAPLFRHPFTEAFATSQPGSLPRVAGMVAKGAGAHEQVSPFDGKTRIIGY
CCCEEEEECCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
NVGRHYPILASATVTREGALAGWYRTLSWFTGLGLAALGLGAILFIFALKHLGSLEREAR
ECCCCCCEEEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MRRLSQTVDQNPNMILTTDSRGVIDYANSSFYRFTGFEPDQVIGATPRILKSDETPPEVF
HHHHHHHHCCCCCEEEEECCCCEEEECCCCEEEECCCCCCHHCCCCCHHHCCCCCCHHHH
VDLWQTIRAGREWRGELVNRRRDGQTYWASVVISPVLDEESGLCGFVGMQEDISERKRIE
HHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHH
GRVAELVAELKRSNEELENFAYVASHDLRQPLRMINSYLGLLRKRLAASFDQEAEEFFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDGARRLDLMIVDLLEFSRIGKQSTREMLDLNGVVADGMQNLAVAIRDCGAEISVAPGL
HCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCC
PTIPGDRSELTRLFQNLIGNALKYCPEERKPVVDISCRDGGREWILSVRDNGIGIEAECL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHH
EKVFGIFQRMVSRDKYEGTGIGLAVCRKIAEHHGGRIWVESVVDHGSTFHVALPKA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MVSPSGQSCKIGRMKAAGRNMDAVRPAGLGESDESEALGFRRLRRWLVAGFVAANLFFAI
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLVMVWLGPRYALEEAGRSTSTLALALSEQVEATIRSEAAILTSLQREIRSRGGVAAFD
HHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
ETAWYQMFMAHLDLFSDDPADKPMHALFFVDSTGIASASSVSNPTRQADASMRPYFIFHR
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEEC
DHPGDELHISEISQSKITGLWVFFLTQRINGPDGSFQGVLGMSLRINRFEELFAHLRLPA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DGSIVIQRLDGAPLFRHPFTEAFATSQPGSLPRVAGMVAKGAGAHEQVSPFDGKTRIIGY
CCCEEEEECCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
NVGRHYPILASATVTREGALAGWYRTLSWFTGLGLAALGLGAILFIFALKHLGSLEREAR
ECCCCCCEEEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MRRLSQTVDQNPNMILTTDSRGVIDYANSSFYRFTGFEPDQVIGATPRILKSDETPPEVF
HHHHHHHHCCCCCEEEEECCCCEEEECCCCEEEECCCCCCHHCCCCCHHHCCCCCCHHHH
VDLWQTIRAGREWRGELVNRRRDGQTYWASVVISPVLDEESGLCGFVGMQEDISERKRIE
HHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHH
GRVAELVAELKRSNEELENFAYVASHDLRQPLRMINSYLGLLRKRLAASFDQEAEEFFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDGARRLDLMIVDLLEFSRIGKQSTREMLDLNGVVADGMQNLAVAIRDCGAEISVAPGL
HCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCC
PTIPGDRSELTRLFQNLIGNALKYCPEERKPVVDISCRDGGREWILSVRDNGIGIEAECL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHH
EKVFGIFQRMVSRDKYEGTGIGLAVCRKIAEHHGGRIWVESVVDHGSTFHVALPKA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]