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The map label for this gene is caiD [C]

Identifier: 83311660

GI number: 83311660

Start: 2743906

End: 2744964

Strand: Reverse

Name: caiD [C]

Synonym: amb2561

Alternate gene names: 83311660

Gene position: 2744964-2743906 (Counterclockwise)

Preceding gene: 83311665

Following gene: 83311659

Centisome position: 55.26

GC content: 65.72

Gene sequence:

>1059_bases
ATGGACGGCGAGACTCTCATCTCCAGCGGCGGGCGGCTTGGACGGATCGTTCTGAACCGGCCCAAGGTGCTGAACGCGCT
GTCCGCCCGGCAATACCACGACATCACCGCCTGTCTCGTCAGCTGGGAGAGCGATCCTGACGTGGCGGTGATTCTGATCG
AGGGCGAGGGCGAGCGGGCGTTCTGCGCCGGCGGCGACATCCGCATGGTGTGGGATGCGGCCCGGCGCGGTGATTCCGAG
TTCAGCCACGATGTCTTTCGCACGGAATACCGCCTTAACCGGCGCATCCATGCCTATCCAAAGCCTTACGTGTCGGTGCT
TGATGGCATCTGCATGGGGGGAGGGGCCAGATTGTCGGTCAATGGCCGGTTCCGCGTCGCCACCGAGCGTACCCGCTTCG
CCATGCCGGAGACGGGCATCGGCTTTTTTCCCGATGTGGGCGCCACCCATTTTCTCAACCGCTGTCCCGGTGATCTGGGA
CTCTATCTCGGCCTTACGGGCAAGCAGTTGGGGCCGGCGGACTGCCTGTGGGCGGGCATCGCCACCCATTTCGTCCCGGC
CGCCCGGGTGGATGACCTGCGAGCGGGATTGCGCGTCGCGGCGCAATCAGCCGATCCGGAGGATGCGGTGGAGGACGTTC
TGGCGCGCTTTCACCAGCCGGTCGCCGACGGGCCGCTGGTCCGGCACATGGAGGCGCTGGAGCGCTGCTTCGCCCCTCGG
CGCCTGGACGACATGATCGAAGCTCTGCGCCTGGATGGCGGACAATGGGCTTGGGACACCATCTGGGAATTGTCTGGGCG
CGCCCCATTCAGCCTGGCGGTGACTCTGCGGCAACTGCGCGAAGGCCGTGGAATGGGCTTCGATGATGCCATCCGGCGTG
AATTCCGCCTCACCTGGCGGTTCCTGCTGGGGCAGGATTTCCTTGAGGGAATCCGTGCCCAGGTCGTAGATAAGGACAGG
CGGCCCAACTGGAGTCCCTCCAGCCTGGCCGAGGTGGATGAACTGGCGGTCGCGGCCTGCTTCCAGACACTGGGCGACGA
CGAACTGCCGCTGCCGTGA

Upstream 100 bases:

>100_bases
GGTCGGCAACGAACGGGTCTTTGGCAATGGAAAAAATTTCACAAAGTTTTTTTGTTCTGTCAATCATAAATCTAGTCAGC
AAGTAGAGTAAGGGGCGGGC

Downstream 100 bases:

>100_bases
GGAGTGGGTGAGTGCGAGGGAATTGGGGATGAAGCCGGACGTCGATGCGGCCGAGGTGTTGTTCGAGTTCATTCGCCTTG
GCAATGCCGTCAAGGTGACG

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MDGETLISSGGRLGRIVLNRPKVLNALSARQYHDITACLVSWESDPDVAVILIEGEGERAFCAGGDIRMVWDAARRGDSE
FSHDVFRTEYRLNRRIHAYPKPYVSVLDGICMGGGARLSVNGRFRVATERTRFAMPETGIGFFPDVGATHFLNRCPGDLG
LYLGLTGKQLGPADCLWAGIATHFVPAARVDDLRAGLRVAAQSADPEDAVEDVLARFHQPVADGPLVRHMEALERCFAPR
RLDDMIEALRLDGGQWAWDTIWELSGRAPFSLAVTLRQLREGRGMGFDDAIRREFRLTWRFLLGQDFLEGIRAQVVDKDR
RPNWSPSSLAEVDELAVAACFQTLGDDELPLP

Sequences:

>Translated_352_residues
MDGETLISSGGRLGRIVLNRPKVLNALSARQYHDITACLVSWESDPDVAVILIEGEGERAFCAGGDIRMVWDAARRGDSE
FSHDVFRTEYRLNRRIHAYPKPYVSVLDGICMGGGARLSVNGRFRVATERTRFAMPETGIGFFPDVGATHFLNRCPGDLG
LYLGLTGKQLGPADCLWAGIATHFVPAARVDDLRAGLRVAAQSADPEDAVEDVLARFHQPVADGPLVRHMEALERCFAPR
RLDDMIEALRLDGGQWAWDTIWELSGRAPFSLAVTLRQLREGRGMGFDDAIRREFRLTWRFLLGQDFLEGIRAQVVDKDR
RPNWSPSSLAEVDELAVAACFQTLGDDELPLP
>Mature_352_residues
MDGETLISSGGRLGRIVLNRPKVLNALSARQYHDITACLVSWESDPDVAVILIEGEGERAFCAGGDIRMVWDAARRGDSE
FSHDVFRTEYRLNRRIHAYPKPYVSVLDGICMGGGARLSVNGRFRVATERTRFAMPETGIGFFPDVGATHFLNRCPGDLG
LYLGLTGKQLGPADCLWAGIATHFVPAARVDDLRAGLRVAAQSADPEDAVEDVLARFHQPVADGPLVRHMEALERCFAPR
RLDDMIEALRLDGGQWAWDTIWELSGRAPFSLAVTLRQLREGRGMGFDDAIRREFRLTWRFLLGQDFLEGIRAQVVDKDR
RPNWSPSSLAEVDELAVAACFQTLGDDELPLP

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=353, Percent_Identity=41.3597733711048, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI37594469, Length=300, Percent_Identity=41.6666666666667, Blast_Score=232, Evalue=3e-61,
Organism=Homo sapiens, GI194097323, Length=217, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI31542718, Length=190, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI221142681, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787659, Length=186, Percent_Identity=26.8817204301075, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788597, Length=145, Percent_Identity=26.8965517241379, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788682, Length=213, Percent_Identity=27.6995305164319, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=350, Percent_Identity=40.8571428571429, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI25144160, Length=350, Percent_Identity=40.8571428571429, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17554946, Length=192, Percent_Identity=31.7708333333333, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=227, Percent_Identity=27.3127753303965, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=339, Percent_Identity=34.2182890855457, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28571729, Length=345, Percent_Identity=40.8695652173913, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI28571730, Length=345, Percent_Identity=40.8695652173913, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI20129971, Length=202, Percent_Identity=29.2079207920792, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24653477, Length=202, Percent_Identity=29.2079207920792, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 39078; Mature: 39078

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGETLISSGGRLGRIVLNRPKVLNALSARQYHDITACLVSWESDPDVAVILIEGEGERA
CCCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCEE
FCAGGDIRMVWDAARRGDSEFSHDVFRTEYRLNRRIHAYPKPYVSVLDGICMGGGARLSV
EECCCCEEEEEHHHHCCCCHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCCEEEE
NGRFRVATERTRFAMPETGIGFFPDVGATHFLNRCPGDLGLYLGLTGKQLGPADCLWAGI
CCEEEEEECCHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
ATHFVPAARVDDLRAGLRVAAQSADPEDAVEDVLARFHQPVADGPLVRHMEALERCFAPR
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
RLDDMIEALRLDGGQWAWDTIWELSGRAPFSLAVTLRQLREGRGMGFDDAIRREFRLTWR
HHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLLGQDFLEGIRAQVVDKDRRPNWSPSSLAEVDELAVAACFQTLGDDELPLP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDGETLISSGGRLGRIVLNRPKVLNALSARQYHDITACLVSWESDPDVAVILIEGEGERA
CCCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCEE
FCAGGDIRMVWDAARRGDSEFSHDVFRTEYRLNRRIHAYPKPYVSVLDGICMGGGARLSV
EECCCCEEEEEHHHHCCCCHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCCEEEE
NGRFRVATERTRFAMPETGIGFFPDVGATHFLNRCPGDLGLYLGLTGKQLGPADCLWAGI
CCEEEEEECCHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
ATHFVPAARVDDLRAGLRVAAQSADPEDAVEDVLARFHQPVADGPLVRHMEALERCFAPR
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
RLDDMIEALRLDGGQWAWDTIWELSGRAPFSLAVTLRQLREGRGMGFDDAIRREFRLTWR
HHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLLGQDFLEGIRAQVVDKDRRPNWSPSSLAEVDELAVAACFQTLGDDELPLP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA