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The map label for this gene is ackA [H]

Identifier: 83311653

GI number: 83311653

Start: 2736349

End: 2737542

Strand: Reverse

Name: ackA [H]

Synonym: amb2554

Alternate gene names: 83311653

Gene position: 2737542-2736349 (Counterclockwise)

Preceding gene: 83311654

Following gene: 83311652

Centisome position: 55.11

GC content: 65.33

Gene sequence:

>1194_bases
ATGCGTGAAGGTATCCTGGTCATCAATGCCGGCTCGTCCAGCATCAAGTTCTCGCTCTACATCTCCAATGGCGACGAGAA
GCCGCTGCTGTCGTGCAAGGGGCAGGTGGAGGGCATCAACGTCGCCCCCCATTTCATCGCCAAGTCGCCCCATGGCGGGG
TGCTGAACGAGCAGCGCTGGCCCGACCAGCCGAACATGAGCCACGAGGCCCTGTTCAAGTACATGATCGAGTGGATCGAG
GCCCAGTTGGGCGATGCCGAGCTCAAGGCCGCCGGTCACCGGGTGGTCCACGGCGGCTCTCAGTACTCCCAGCCGCTGCT
GGTCAATGACGAGCTGATGGAAGAGCTGGAGAAGCTGATCCCCCTGGCGCCGCTGCACCAGCCCCATAATCTGGCCCCCA
TCCGCGCCCTGACCAAGGTCCATCCCGGCCTGACCCAGGTCGCCTGTTTCGATACCGCCTTCCACCGCTCCAATCCCTGG
ACGGCCCAGAGCTTCGCTCTGCCGCGCAAGATCACCGGCGAAGGCGTCAAGCGCTACGGCTTCCACGGCCTGTCCTACGA
ATTCATCGCCCGCCAGATGCGCCAGCTGTCTCCGGCGGCGGCACGGGGCAAGGTGGTGGTCTGCCATCTGGGCTCCGGCG
CCTCCATGTGCGCCATCGACGGCGGCAAGAGCGTGGCCAGCACCATGGGCTTTACCGCCGTGGACGGCCTGCCCATGGGC
ACCCGCACCGGAACCATGGATGCCGGCGTGATCCTTTACCTGCTGCAGCAGAAGGGCATGACCCCCAAGGAAATCGAGGA
CCTGCTGTACAAGCAGTCCGGCCTGCTGGGCGTGTCGGGGGTCAGCAACGACATGCGCATCCTGCTGGAAAGCTCGGAGC
CCCATGCCGCCGAGGCAGTCGAACTGTTCGTCTATCGCATCTCGCGCGAGCTGGGCTCGCTGGCCGCCGCCATGGGCGGG
CTGGATGCCCTGGTGTTCACCGCCGGCATCGGCGAGCGCTCGCCTCAGATCCGCGAGAGGGTCTGTGCCCATGCCGAGTG
GCTGGGGGTCGAGATGGACCAGGAAGCCAACCAGCGTGATTCCCTGCTGATCAGCGCCGCCGACAGCCCCGTCTCGGTTT
GGGTGATTCCCACCGACGAGGAGATGATGATCGCCAAGCACACCCGCGAGCTGTTACGGAGCTTGCGCGACTAG

Upstream 100 bases:

>100_bases
GTAATGCTTGTCCCTCGCCGGGCGCGGGCTTTCGCCCGCTTGGCCGCCGCCTCAATGGCGGCTGGATACGGCGAGTTGGC
CTCAATGGAGTTTGGGTCCT

Downstream 100 bases:

>100_bases
GTCGGAGCCACTACATGTGGTATGGCTATTGTGCTTCTGGTCAATTCCCTTGGGACATGGCACATTGGCGCCGCGACAGG
AACCAGTCGGGACCGATAAG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MREGILVINAGSSSIKFSLYISNGDEKPLLSCKGQVEGINVAPHFIAKSPHGGVLNEQRWPDQPNMSHEALFKYMIEWIE
AQLGDAELKAAGHRVVHGGSQYSQPLLVNDELMEELEKLIPLAPLHQPHNLAPIRALTKVHPGLTQVACFDTAFHRSNPW
TAQSFALPRKITGEGVKRYGFHGLSYEFIARQMRQLSPAAARGKVVVCHLGSGASMCAIDGGKSVASTMGFTAVDGLPMG
TRTGTMDAGVILYLLQQKGMTPKEIEDLLYKQSGLLGVSGVSNDMRILLESSEPHAAEAVELFVYRISRELGSLAAAMGG
LDALVFTAGIGERSPQIRERVCAHAEWLGVEMDQEANQRDSLLISAADSPVSVWVIPTDEEMMIAKHTRELLRSLRD

Sequences:

>Translated_397_residues
MREGILVINAGSSSIKFSLYISNGDEKPLLSCKGQVEGINVAPHFIAKSPHGGVLNEQRWPDQPNMSHEALFKYMIEWIE
AQLGDAELKAAGHRVVHGGSQYSQPLLVNDELMEELEKLIPLAPLHQPHNLAPIRALTKVHPGLTQVACFDTAFHRSNPW
TAQSFALPRKITGEGVKRYGFHGLSYEFIARQMRQLSPAAARGKVVVCHLGSGASMCAIDGGKSVASTMGFTAVDGLPMG
TRTGTMDAGVILYLLQQKGMTPKEIEDLLYKQSGLLGVSGVSNDMRILLESSEPHAAEAVELFVYRISRELGSLAAAMGG
LDALVFTAGIGERSPQIRERVCAHAEWLGVEMDQEANQRDSLLISAADSPVSVWVIPTDEEMMIAKHTRELLRSLRD
>Mature_397_residues
MREGILVINAGSSSIKFSLYISNGDEKPLLSCKGQVEGINVAPHFIAKSPHGGVLNEQRWPDQPNMSHEALFKYMIEWIE
AQLGDAELKAAGHRVVHGGSQYSQPLLVNDELMEELEKLIPLAPLHQPHNLAPIRALTKVHPGLTQVACFDTAFHRSNPW
TAQSFALPRKITGEGVKRYGFHGLSYEFIARQMRQLSPAAARGKVVVCHLGSGASMCAIDGGKSVASTMGFTAVDGLPMG
TRTGTMDAGVILYLLQQKGMTPKEIEDLLYKQSGLLGVSGVSNDMRILLESSEPHAAEAVELFVYRISRELGSLAAAMGG
LDALVFTAGIGERSPQIRERVCAHAEWLGVEMDQEANQRDSLLISAADSPVSVWVIPTDEEMMIAKHTRELLRSLRD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=390, Percent_Identity=38.7179487179487, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1788633, Length=401, Percent_Identity=34.6633416458853, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43258; Mature: 43258

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGILVINAGSSSIKFSLYISNGDEKPLLSCKGQVEGINVAPHFIAKSPHGGVLNEQRW
CCCCEEEEECCCCEEEEEEEEECCCCCCEEECCCCCCEEEECHHHHCCCCCCCCCCCCCC
PDQPNMSHEALFKYMIEWIEAQLGDAELKAAGHRVVHGGSQYSQPLLVNDELMEELEKLI
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCCEEECHHHHHHHHHHC
PLAPLHQPHNLAPIRALTKVHPGLTQVACFDTAFHRSNPWTAQSFALPRKITGEGVKRYG
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCHHCCCCHHHHC
FHGLSYEFIARQMRQLSPAAARGKVVVCHLGSGASMCAIDGGKSVASTMGFTAVDGLPMG
CCCCCHHHHHHHHHHCCCHHHCCCEEEEEECCCCCEEEECCCCHHHHHCCCHHCCCCCCC
TRTGTMDAGVILYLLQQKGMTPKEIEDLLYKQSGLLGVSGVSNDMRILLESSEPHAAEAV
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHH
ELFVYRISRELGSLAAAMGGLDALVFTAGIGERSPQIRERVCAHAEWLGVEMDQEANQRD
HHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
SLLISAADSPVSVWVIPTDEEMMIAKHTRELLRSLRD
CEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MREGILVINAGSSSIKFSLYISNGDEKPLLSCKGQVEGINVAPHFIAKSPHGGVLNEQRW
CCCCEEEEECCCCEEEEEEEEECCCCCCEEECCCCCCEEEECHHHHCCCCCCCCCCCCCC
PDQPNMSHEALFKYMIEWIEAQLGDAELKAAGHRVVHGGSQYSQPLLVNDELMEELEKLI
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCCEEECHHHHHHHHHHC
PLAPLHQPHNLAPIRALTKVHPGLTQVACFDTAFHRSNPWTAQSFALPRKITGEGVKRYG
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCHHCCCCHHHHC
FHGLSYEFIARQMRQLSPAAARGKVVVCHLGSGASMCAIDGGKSVASTMGFTAVDGLPMG
CCCCCHHHHHHHHHHCCCHHHCCCEEEEEECCCCCEEEECCCCHHHHHCCCHHCCCCCCC
TRTGTMDAGVILYLLQQKGMTPKEIEDLLYKQSGLLGVSGVSNDMRILLESSEPHAAEAV
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHH
ELFVYRISRELGSLAAAMGGLDALVFTAGIGERSPQIRERVCAHAEWLGVEMDQEANQRD
HHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
SLLISAADSPVSVWVIPTDEEMMIAKHTRELLRSLRD
CEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA