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The map label for this gene is argS

Identifier: 83311628

GI number: 83311628

Start: 2710282

End: 2712012

Strand: Reverse

Name: argS

Synonym: amb2529

Alternate gene names: 83311628

Gene position: 2712012-2710282 (Counterclockwise)

Preceding gene: 83311629

Following gene: 83311627

Centisome position: 54.6

GC content: 66.15

Gene sequence:

>1731_bases
ATGAACCTGTTCAAATACTTCCGCGAAGAAATTATCAAGTCGGTCGAAGCGATCGTTCCCGGCCTCGACACCTCCAAGGT
GACGGCCGAGCCGCCGCGAGAGGTCAGCCACGGCGACGTGGCCACCAATGCCGCCATGGTGCTGACCAAGGCGGCGGGCA
TGAAGCCCCGCGATCTGGCCGAGAAGATCGCCGAGGTTTTGCGCGCCCATCCGGCGGTGACCGGAGTGGAGGTGGCCGGT
CCCGGCTTCATCAACCTGCGTCTCGCCGATTCCTTCTGGTTCGAGCGTCTGGCCGAGGTTCTCGCCGCCGGAACCGCCTA
TGGCCAGTCGGACCTGGGCCGGGGCCACAAGGTCAACGTGGAATACGTCTCGGCCAACCCCACCGGTCCCATGCATATCG
GCCACGCCCGCGGCGCGGTGTTCGGCGATGCCCTGGCCTCGCTGCTGGTCAAGGCCGGCTATGACGTGACCCGCGAGTAC
TATGTCAACGACGCCGGCTCCCAGGTGGACGTCCTGGCCCGCTCGGCCTTCCTGCGCTACCGGGAAGCCCTGGGCGAGGA
AATCGGCGAGATCCCCGAAGGCCTGTATCCCGGCGAATACCTCAAGCCCGCCGGTGAGGCCCTGGCCAAGAAGCATGGCC
CTGCGCTGAAGGACAAGCCCGAGGAAGAGTGGCTGCCCGAGCTGCGCGGCTTTGCCGTCGACGCCATGCTGGACATGATC
AAGGGTGATCTGGCTGGGCTGGGCGTGCGCCACGACGTGTTCGTCTCCGAGCGCGGGCTGGTGGAGGCCGGCAAGGTTCA
GGACGCCCTGGACTATCTGACCGCCAAGGGCCTGATCTACGAAGGCGTGCTGGAGCCCCCCAAGGGCAAGCTGCCTGACG
ATTGGGAGGCGCGGCCGCAAACCCTGTTCAAGGCCACCGAGTTCGGCGACGACGTCGACCGTCCGCTGAAAAAGTCGGAC
GGCTCGTGGACCTATTTCGCCTCGGACATCGCCTATCACCTGGACAAATACCGACGCGGCTTCGGCGCGATGATCGACGT
GTGGGGCGCCGATCACGGCGGCTACGTCAAGCGCATGCAGGCGGCGGTCAAGGCGGTGAGCGAGGGCGGCGGCGATCTCG
ACGTCAAGCTCTGCCAGATGGTCAACCTCTTGAAGGGCGGCCAGCCCTACAAGATGAGCAAGCGGGCCGGTACCTTCGTC
ACGCTGCGCGACCTGGTGGAGGCGGTGGGCAAGGACGTGGTCCGCTTCATCATGCTGACCCGCAAGAACGACGCCCATCT
GGATTTCGATCTGGACAAGGTGCTGGAGCAGAGCCGCGATAATCCGGTGTTCTACGTCCAGTACGCCCATGCCCGCTGTC
ACTCGGTGATGCGCCACGCCGCCGGCATGTGGCCGGACGCCGTGGGCCCGGTCCCCGGCGTCGAGGTTCTGGCACACTTG
ACCGACCCGGCCGAGCTTGGTTTGATCAGGCTGTTGGCCGGTTGGCCGCGCCTGGTGGAAAGCGCGGCCGAGGCCCACGA
GCCGCATCGCGTGGCGTTCTACCTTTACGACTTGGCCGCCGCCTTCCATGGGCTGTGGAACAAGGGCAAGGACGACACCA
GCCTGCGGTTCCTGATCGAGGACGACCGCGAGCTGTCCTTGGCCCGCCTGGGCCTGCTGCGCGCGGTGGTGGGGGTGATC
GCCTCGGGGCTTGGCATCTTCGGTGTCGCCCCGGTCGAAGAGATGCGTTGA

Upstream 100 bases:

>100_bases
CCGCCCGCGTGGTGGCCGATTACATTGCCGGCATGACTGATCGTTTTGCCCTCGACGAGCACCGCCGGCTGTTCGACCTG
CAAGAGAAGCCTTGAGAAAA

Downstream 100 bases:

>100_bases
TAAGGGGAGACGCGCTGATATGGCCAAAAGCCCTGGCGACGATTACGAGCGTGACCTGCTGGATATCATTCCCGAGCGCT
ATAATGACGCCGATGCCGAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNLFKYFREEIIKSVEAIVPGLDTSKVTAEPPREVSHGDVATNAAMVLTKAAGMKPRDLAEKIAEVLRAHPAVTGVEVAG
PGFINLRLADSFWFERLAEVLAAGTAYGQSDLGRGHKVNVEYVSANPTGPMHIGHARGAVFGDALASLLVKAGYDVTREY
YVNDAGSQVDVLARSAFLRYREALGEEIGEIPEGLYPGEYLKPAGEALAKKHGPALKDKPEEEWLPELRGFAVDAMLDMI
KGDLAGLGVRHDVFVSERGLVEAGKVQDALDYLTAKGLIYEGVLEPPKGKLPDDWEARPQTLFKATEFGDDVDRPLKKSD
GSWTYFASDIAYHLDKYRRGFGAMIDVWGADHGGYVKRMQAAVKAVSEGGGDLDVKLCQMVNLLKGGQPYKMSKRAGTFV
TLRDLVEAVGKDVVRFIMLTRKNDAHLDFDLDKVLEQSRDNPVFYVQYAHARCHSVMRHAAGMWPDAVGPVPGVEVLAHL
TDPAELGLIRLLAGWPRLVESAAEAHEPHRVAFYLYDLAAAFHGLWNKGKDDTSLRFLIEDDRELSLARLGLLRAVVGVI
ASGLGIFGVAPVEEMR

Sequences:

>Translated_576_residues
MNLFKYFREEIIKSVEAIVPGLDTSKVTAEPPREVSHGDVATNAAMVLTKAAGMKPRDLAEKIAEVLRAHPAVTGVEVAG
PGFINLRLADSFWFERLAEVLAAGTAYGQSDLGRGHKVNVEYVSANPTGPMHIGHARGAVFGDALASLLVKAGYDVTREY
YVNDAGSQVDVLARSAFLRYREALGEEIGEIPEGLYPGEYLKPAGEALAKKHGPALKDKPEEEWLPELRGFAVDAMLDMI
KGDLAGLGVRHDVFVSERGLVEAGKVQDALDYLTAKGLIYEGVLEPPKGKLPDDWEARPQTLFKATEFGDDVDRPLKKSD
GSWTYFASDIAYHLDKYRRGFGAMIDVWGADHGGYVKRMQAAVKAVSEGGGDLDVKLCQMVNLLKGGQPYKMSKRAGTFV
TLRDLVEAVGKDVVRFIMLTRKNDAHLDFDLDKVLEQSRDNPVFYVQYAHARCHSVMRHAAGMWPDAVGPVPGVEVLAHL
TDPAELGLIRLLAGWPRLVESAAEAHEPHRVAFYLYDLAAAFHGLWNKGKDDTSLRFLIEDDRELSLARLGLLRAVVGVI
ASGLGIFGVAPVEEMR
>Mature_576_residues
MNLFKYFREEIIKSVEAIVPGLDTSKVTAEPPREVSHGDVATNAAMVLTKAAGMKPRDLAEKIAEVLRAHPAVTGVEVAG
PGFINLRLADSFWFERLAEVLAAGTAYGQSDLGRGHKVNVEYVSANPTGPMHIGHARGAVFGDALASLLVKAGYDVTREY
YVNDAGSQVDVLARSAFLRYREALGEEIGEIPEGLYPGEYLKPAGEALAKKHGPALKDKPEEEWLPELRGFAVDAMLDMI
KGDLAGLGVRHDVFVSERGLVEAGKVQDALDYLTAKGLIYEGVLEPPKGKLPDDWEARPQTLFKATEFGDDVDRPLKKSD
GSWTYFASDIAYHLDKYRRGFGAMIDVWGADHGGYVKRMQAAVKAVSEGGGDLDVKLCQMVNLLKGGQPYKMSKRAGTFV
TLRDLVEAVGKDVVRFIMLTRKNDAHLDFDLDKVLEQSRDNPVFYVQYAHARCHSVMRHAAGMWPDAVGPVPGVEVLAHL
TDPAELGLIRLLAGWPRLVESAAEAHEPHRVAFYLYDLAAAFHGLWNKGKDDTSLRFLIEDDRELSLARLGLLRAVVGVI
ASGLGIFGVAPVEEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=628, Percent_Identity=24.3630573248408, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1788184, Length=596, Percent_Identity=26.3422818791946, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71985068, Length=560, Percent_Identity=23.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985061, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320548, Length=640, Percent_Identity=26.09375, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI18859963, Length=612, Percent_Identity=22.3856209150327, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571570, Length=504, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MAGSA (Q2W492)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_421892.1
- ProteinModelPortal:   Q2W492
- STRING:   Q2W492
- GeneID:   3805634
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2529
- NMPDR:   fig|342108.5.peg.2231
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- PhylomeDB:   Q2W492
- ProtClustDB:   PRK01611
- BioCyc:   MMAG342108:AMB2529-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63000; Mature: 63000

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFKYFREEIIKSVEAIVPGLDTSKVTAEPPREVSHGDVATNAAMVLTKAAGMKPRDLA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
EKIAEVLRAHPAVTGVEVAGPGFINLRLADSFWFERLAEVLAAGTAYGQSDLGRGHKVNV
HHHHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEE
EYVSANPTGPMHIGHARGAVFGDALASLLVKAGYDVTREYYVNDAGSQVDVLARSAFLRY
EEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHHHEECCCCCHHHHHHHHHHHHH
REALGEEIGEIPEGLYPGEYLKPAGEALAKKHGPALKDKPEEEWLPELRGFAVDAMLDMI
HHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGDLAGLGVRHDVFVSERGLVEAGKVQDALDYLTAKGLIYEGVLEPPKGKLPDDWEARPQ
HHHHHCCCCCHHEEECCCCCCCHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCHH
TLFKATEFGDDVDRPLKKSDGSWTYFASDIAYHLDKYRRGFGAMIDVWGADHGGYVKRMQ
HHHHHHHCCCHHCCHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
AAVKAVSEGGGDLDVKLCQMVNLLKGGQPYKMSKRAGTFVTLRDLVEAVGKDVVRFIMLT
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RKNDAHLDFDLDKVLEQSRDNPVFYVQYAHARCHSVMRHAAGMWPDAVGPVPGVEVLAHL
CCCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHC
TDPAELGLIRLLAGWPRLVESAAEAHEPHRVAFYLYDLAAAFHGLWNKGKDDTSLRFLIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
DDRELSLARLGLLRAVVGVIASGLGIFGVAPVEEMR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
>Mature Secondary Structure
MNLFKYFREEIIKSVEAIVPGLDTSKVTAEPPREVSHGDVATNAAMVLTKAAGMKPRDLA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
EKIAEVLRAHPAVTGVEVAGPGFINLRLADSFWFERLAEVLAAGTAYGQSDLGRGHKVNV
HHHHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEE
EYVSANPTGPMHIGHARGAVFGDALASLLVKAGYDVTREYYVNDAGSQVDVLARSAFLRY
EEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHHHEECCCCCHHHHHHHHHHHHH
REALGEEIGEIPEGLYPGEYLKPAGEALAKKHGPALKDKPEEEWLPELRGFAVDAMLDMI
HHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGDLAGLGVRHDVFVSERGLVEAGKVQDALDYLTAKGLIYEGVLEPPKGKLPDDWEARPQ
HHHHHCCCCCHHEEECCCCCCCHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCHH
TLFKATEFGDDVDRPLKKSDGSWTYFASDIAYHLDKYRRGFGAMIDVWGADHGGYVKRMQ
HHHHHHHCCCHHCCHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
AAVKAVSEGGGDLDVKLCQMVNLLKGGQPYKMSKRAGTFVTLRDLVEAVGKDVVRFIMLT
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RKNDAHLDFDLDKVLEQSRDNPVFYVQYAHARCHSVMRHAAGMWPDAVGPVPGVEVLAHL
CCCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHC
TDPAELGLIRLLAGWPRLVESAAEAHEPHRVAFYLYDLAAAFHGLWNKGKDDTSLRFLIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
DDRELSLARLGLLRAVVGVIASGLGIFGVAPVEEMR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA