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The map label for this gene is aphA [H]

Identifier: 83311312

GI number: 83311312

Start: 2412184

End: 2414055

Strand: Reverse

Name: aphA [H]

Synonym: amb2213

Alternate gene names: 83311312

Gene position: 2414055-2412184 (Counterclockwise)

Preceding gene: 83311313

Following gene: 83311307

Centisome position: 48.6

GC content: 64.58

Gene sequence:

>1872_bases
ATGACCTTTGCCAGCGCCCTGGCCCGCCGAGGCAGCGTCGCCCATCGCCTGATCATCCGTCTAGGCGTGACGGGCCTTGC
CGTAGCGCTCCTCATCGCGGCCGGGCTGGTCACCGCCGATTACCAGATCACCCTCCAGCGGACGGACGAGCGCTTCCACC
AGATCGAGGCGGGCTATCTGGCCAGCGTGACGGAAAACGTCTGGCTGCAGGATGGCGAGCGCCTGGGCCAACTGGTGGCC
GGCATTCGCCAGACGCCCTATGTCCAGCTCGTCCGCGTCACCGACGAGACCGGAGCCGTCCTGGTTGCGGATGGCCCCGG
CGGCGACGGCGAGATGATCACCAGACGCTATCCCCTGGCGCGGGTCTATTACGGCAAGGAACTGCGCATCGGCTTGCTGG
AGGTCTCGGTGAGCCAACGCCTGCTTCTGCGGCCCGTCCTCCACCGGGCCGGATTGCTGCTCCTGGCCAACATCATCCTG
ATGGCGGGAATTCTTGCCGCCCTTTACTGGCAGGTCTACCGGCTGATCGCTCAGCCGCTTGCCCAAATGGCCGCCCATGT
GCGCCACATGAACCTGGACCGGGCCGATTGGGAAATGCAACTGGTCTCTCCCCACGACGAGTTGAAGGACCTGGCGGCGG
CCTATGCCGAGATGCGCCAAGCCATCGATCAGGGCTATCACGCCCTGCGGTCCAGAGAGGAACATCTGCGCATTGTATTT
GACAACTCGCCCGTTTCCCTTTGGGAAGAGGATTTTTCCAGGGTCAAGCGAGAGGTGGACGCCCTGCGCGGGTCCATGGA
TCTGGAAATCGAGGTCTATCTGGAGGCCCATCCGGACTTCGTCGTCCGCTGCGCCGCCCTGGTGGAGGTGGTCAACGTCA
ACGCCGCCACCCTGGCTCTGCACAATGCCCCCAGCCGGGCGGCGCTGCTCGGCAACCTGCAAAAAACATTCACCACCGCG
TCATTCCACACCTTTCGCCGCCAGATCGTCGCCATATGGAAGGGCGAGACCGAACTGTCCGTGGAAGGCGAGGTCAAGAC
CCTCAGCGGTGACCGGCGCCAGGTCATGCTCCACTGGCGCGTTCCCCCCGGCCATGAAGGCTGTCTCGACCGGGTGTTGG
TGGCGCTGGAAAACATTACCGAGCGCAAAGCGGCCGAGCAGGCCCTGGCTGCCTCGCTGGAAAAGCTGGTCCGTACCAAC
CAGGAACTGGAGAGGTTGACCGAGATCACCGCCCACGACCTGCAGGAACCGGCACGCGGCATCGTCAGCTTCAGCCAGTT
ACTCGAGCGCCGCATCGGCCCGACGCTGGACGCCGACACGAGCGATTTGCTGGGCTACCTGACCAATGCCGGCCGGCGGA
TGCAAGATCAGGTCCGCGGCCTTCTCGCCTATGCCCAGGTCGCACCGCTGGATTCCCCCGTCGAGCCGCAAAGCCTGGAT
GCGGCTCTGCATGGAGCATGTGAAGCCTTGGCCGATCCGATCGGACAATGCGGCGCCGTCGTTGAGGCGGAGCCGCTGCC
CCGGGTGATGGGCAACGAGGCCCTTCTTATCGACCTTTTCATCCGGTTGATCGACAATGCCCTGAAGTTTGCGCGCGCCG
AGGCGCCACCGCGCATCACCATTACGGCGAGCGTCAGCGACACCATGGTCACCGTCGCCGTGGCGGATCACGGCATCGGT
ATCCTGCCCTCCTATGCCGACGATGTTTTCCAGGTGTTCCGGCGGCTCCATGGCCCCGACCACTTCCCTGGCGTGGGGAT
CGGCCTGGCCATCTGCCGTAAGATCGTCGAGCGCCTGGGCGGCAACATCTGGATCGACACTACGGTCACCGAAGGTTGCA
CCGTTCGCTTCAGCCTGCCGCCTGCCCCATAG

Upstream 100 bases:

>100_bases
CCATGGCCGAAGCGCTGCGGCGGATGAAAGCCGACGGCTCCTACGAGACCATTGCCCGCAAAGTCTTCGGAGGACTCGGC
TCCTCGGTGACGGAGATGAA

Downstream 100 bases:

>100_bases
AAAAAAGGGCACCACCCGACGGATGGCGCCCTTCGACATCAATGGACGAAATTTTACAGCCCCCAGCCGTTGGCCTGTTC
CCGCGCCGAAAGCGAGAAGG

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTFASALARRGSVAHRLIIRLGVTGLAVALLIAAGLVTADYQITLQRTDERFHQIEAGYLASVTENVWLQDGERLGQLVA
GIRQTPYVQLVRVTDETGAVLVADGPGGDGEMITRRYPLARVYYGKELRIGLLEVSVSQRLLLRPVLHRAGLLLLANIIL
MAGILAALYWQVYRLIAQPLAQMAAHVRHMNLDRADWEMQLVSPHDELKDLAAAYAEMRQAIDQGYHALRSREEHLRIVF
DNSPVSLWEEDFSRVKREVDALRGSMDLEIEVYLEAHPDFVVRCAALVEVVNVNAATLALHNAPSRAALLGNLQKTFTTA
SFHTFRRQIVAIWKGETELSVEGEVKTLSGDRRQVMLHWRVPPGHEGCLDRVLVALENITERKAAEQALAASLEKLVRTN
QELERLTEITAHDLQEPARGIVSFSQLLERRIGPTLDADTSDLLGYLTNAGRRMQDQVRGLLAYAQVAPLDSPVEPQSLD
AALHGACEALADPIGQCGAVVEAEPLPRVMGNEALLIDLFIRLIDNALKFARAEAPPRITITASVSDTMVTVAVADHGIG
ILPSYADDVFQVFRRLHGPDHFPGVGIGLAICRKIVERLGGNIWIDTTVTEGCTVRFSLPPAP

Sequences:

>Translated_623_residues
MTFASALARRGSVAHRLIIRLGVTGLAVALLIAAGLVTADYQITLQRTDERFHQIEAGYLASVTENVWLQDGERLGQLVA
GIRQTPYVQLVRVTDETGAVLVADGPGGDGEMITRRYPLARVYYGKELRIGLLEVSVSQRLLLRPVLHRAGLLLLANIIL
MAGILAALYWQVYRLIAQPLAQMAAHVRHMNLDRADWEMQLVSPHDELKDLAAAYAEMRQAIDQGYHALRSREEHLRIVF
DNSPVSLWEEDFSRVKREVDALRGSMDLEIEVYLEAHPDFVVRCAALVEVVNVNAATLALHNAPSRAALLGNLQKTFTTA
SFHTFRRQIVAIWKGETELSVEGEVKTLSGDRRQVMLHWRVPPGHEGCLDRVLVALENITERKAAEQALAASLEKLVRTN
QELERLTEITAHDLQEPARGIVSFSQLLERRIGPTLDADTSDLLGYLTNAGRRMQDQVRGLLAYAQVAPLDSPVEPQSLD
AALHGACEALADPIGQCGAVVEAEPLPRVMGNEALLIDLFIRLIDNALKFARAEAPPRITITASVSDTMVTVAVADHGIG
ILPSYADDVFQVFRRLHGPDHFPGVGIGLAICRKIVERLGGNIWIDTTVTEGCTVRFSLPPAP
>Mature_622_residues
TFASALARRGSVAHRLIIRLGVTGLAVALLIAAGLVTADYQITLQRTDERFHQIEAGYLASVTENVWLQDGERLGQLVAG
IRQTPYVQLVRVTDETGAVLVADGPGGDGEMITRRYPLARVYYGKELRIGLLEVSVSQRLLLRPVLHRAGLLLLANIILM
AGILAALYWQVYRLIAQPLAQMAAHVRHMNLDRADWEMQLVSPHDELKDLAAAYAEMRQAIDQGYHALRSREEHLRIVFD
NSPVSLWEEDFSRVKREVDALRGSMDLEIEVYLEAHPDFVVRCAALVEVVNVNAATLALHNAPSRAALLGNLQKTFTTAS
FHTFRRQIVAIWKGETELSVEGEVKTLSGDRRQVMLHWRVPPGHEGCLDRVLVALENITERKAAEQALAASLEKLVRTNQ
ELERLTEITAHDLQEPARGIVSFSQLLERRIGPTLDADTSDLLGYLTNAGRRMQDQVRGLLAYAQVAPLDSPVEPQSLDA
ALHGACEALADPIGQCGAVVEAEPLPRVMGNEALLIDLFIRLIDNALKFARAEAPPRITITASVSDTMVTVAVADHGIGI
LPSYADDVFQVFRRLHGPDHFPGVGIGLAICRKIVERLGGNIWIDTTVTEGCTVRFSLPPAP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=300, Percent_Identity=27.3333333333333, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68599; Mature: 68468

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFASALARRGSVAHRLIIRLGVTGLAVALLIAAGLVTADYQITLQRTDERFHQIEAGYL
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHH
ASVTENVWLQDGERLGQLVAGIRQTPYVQLVRVTDETGAVLVADGPGGDGEMITRRYPLA
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEECCCCC
RVYYGKELRIGLLEVSVSQRLLLRPVLHRAGLLLLANIILMAGILAALYWQVYRLIAQPL
EEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQMAAHVRHMNLDRADWEMQLVSPHDELKDLAAAYAEMRQAIDQGYHALRSREEHLRIVF
HHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
DNSPVSLWEEDFSRVKREVDALRGSMDLEIEVYLEAHPDFVVRCAALVEVVNVNAATLAL
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHEEEE
HNAPSRAALLGNLQKTFTTASFHTFRRQIVAIWKGETELSVEGEVKTLSGDRRQVMLHWR
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCEEECCCCCEEEEEEEE
VPPGHEGCLDRVLVALENITERKAAEQALAASLEKLVRTNQELERLTEITAHDLQEPARG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVSFSQLLERRIGPTLDADTSDLLGYLTNAGRRMQDQVRGLLAYAQVAPLDSPVEPQSLD
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AALHGACEALADPIGQCGAVVEAEPLPRVMGNEALLIDLFIRLIDNALKFARAEAPPRIT
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITASVSDTMVTVAVADHGIGILPSYADDVFQVFRRLHGPDHFPGVGIGLAICRKIVERLG
EEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
GNIWIDTTVTEGCTVRFSLPPAP
CCEEEEEEECCCEEEEEECCCCC
>Mature Secondary Structure 
TFASALARRGSVAHRLIIRLGVTGLAVALLIAAGLVTADYQITLQRTDERFHQIEAGYL
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHH
ASVTENVWLQDGERLGQLVAGIRQTPYVQLVRVTDETGAVLVADGPGGDGEMITRRYPLA
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEECCCCC
RVYYGKELRIGLLEVSVSQRLLLRPVLHRAGLLLLANIILMAGILAALYWQVYRLIAQPL
EEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQMAAHVRHMNLDRADWEMQLVSPHDELKDLAAAYAEMRQAIDQGYHALRSREEHLRIVF
HHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
DNSPVSLWEEDFSRVKREVDALRGSMDLEIEVYLEAHPDFVVRCAALVEVVNVNAATLAL
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHEEEE
HNAPSRAALLGNLQKTFTTASFHTFRRQIVAIWKGETELSVEGEVKTLSGDRRQVMLHWR
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCEEECCCCCEEEEEEEE
VPPGHEGCLDRVLVALENITERKAAEQALAASLEKLVRTNQELERLTEITAHDLQEPARG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVSFSQLLERRIGPTLDADTSDLLGYLTNAGRRMQDQVRGLLAYAQVAPLDSPVEPQSLD
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AALHGACEALADPIGQCGAVVEAEPLPRVMGNEALLIDLFIRLIDNALKFARAEAPPRIT
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITASVSDTMVTVAVADHGIGILPSYADDVFQVFRRLHGPDHFPGVGIGLAICRKIVERLG
EEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
GNIWIDTTVTEGCTVRFSLPPAP
CCEEEEEEECCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]