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The map label for this gene is appC [H]

Identifier: 83311075

GI number: 83311075

Start: 2135302

End: 2135538

Strand: Reverse

Name: appC [H]

Synonym: amb1976

Alternate gene names: 83311075

Gene position: 2135538-2135302 (Counterclockwise)

Preceding gene: 83311076

Following gene: 83311072

Centisome position: 42.99

GC content: 67.93

Gene sequence:

>237_bases
GTGGGCAACATCATCCTGATCGAAAGCGCCCTGTCCTTCCTGGGCCTCGGCATCCGCCCACCCCTGGCGTCATGGGGCAA
CATGCTGACCGGGGCCATGGACGTCGTCTGGAGCGCCCCACTGATGGCCTTCTGGCCGGGCGCCGCCATCTTCGCCACCG
TGCTGGGCTTCAACCTGCTGGGCGATGGATTGCAGCGGGCCCTGGACCCCAAGGGGCAGACCGCCCTCAGTGGCTGA

Upstream 100 bases:

>100_bases
TGCGCGCAGCCGAGGCCATGGGCGCCCGGCCCGGCCGGATCATGCTGCGCCACATCCTCCCCAATGTGGCCTCGCCCATG
GTGGTGGCACCACCCTGTCG

Downstream 100 bases:

>100_bases
ACAGCACCGGCACCGTCATGGAATCCAGCATGTGCCGGGTGGCGCCGCCCAGAACCATCTCGCGCAGGCGCGAGCGGCCA
TAGCCGCCCATGACCATCAG

Product: hypothetical protein

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 78; Mature: 77

Protein sequence:

>78_residues
MGNIILIESALSFLGLGIRPPLASWGNMLTGAMDVVWSAPLMAFWPGAAIFATVLGFNLLGDGLQRALDPKGQTALSG

Sequences:

>Translated_78_residues
MGNIILIESALSFLGLGIRPPLASWGNMLTGAMDVVWSAPLMAFWPGAAIFATVLGFNLLGDGLQRALDPKGQTALSG
>Mature_77_residues
GNIILIESALSFLGLGIRPPLASWGNMLTGAMDVVWSAPLMAFWPGAAIFATVLGFNLLGDGLQRALDPKGQTALSG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789889, Length=71, Percent_Identity=46.4788732394366, Blast_Score=76, Evalue=4e-16,
Organism=Escherichia coli, GI1787054, Length=71, Percent_Identity=54.9295774647887, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1789964, Length=69, Percent_Identity=52.1739130434783, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1787498, Length=71, Percent_Identity=43.6619718309859, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1787760, Length=72, Percent_Identity=43.0555555555556, Blast_Score=59, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 8101; Mature: 7969

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIILIESALSFLGLGIRPPLASWGNMLTGAMDVVWSAPLMAFWPGAAIFATVLGFNLL
CCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
GDGLQRALDPKGQTALSG
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GNIILIESALSFLGLGIRPPLASWGNMLTGAMDVVWSAPLMAFWPGAAIFATVLGFNLL
CCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
GDGLQRALDPKGQTALSG
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]