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The map label for this gene is nodT [H]

Identifier: 83310973

GI number: 83310973

Start: 2018669

End: 2020099

Strand: Reverse

Name: nodT [H]

Synonym: amb1874

Alternate gene names: 83310973

Gene position: 2020099-2018669 (Counterclockwise)

Preceding gene: 83310974

Following gene: 83310972

Centisome position: 40.67

GC content: 71.42

Gene sequence:

>1431_bases
ATGTCTAAGCGCAAGATCGCTCCCTCCGCCCTGGTGCTGACCGGGCTGCTGCTCGCCGCCTGCACCAGCCCGGCCGGGCC
GCAAGATTCCGGGATCGAGACCCCGTCCCTGTGGAGCCGCCTGACCGGAAGCGCGCCGGCCAAGGCCGACCCCACCGCGC
CGCTGGTCCTGGGCCCCGATGCTGAGGTCGAGCAGACCTGGTGGCGACGCTTCGGCGATCCCACCCTCGACACCCTGGTG
GCCGACGCCCTGGCCGGCAACCAGACCCTGGCCATGGCCAAGGCTCGGGTCGAGGAGGCCCAGGCGGCGCGCGGCCTCGC
CCGCTCGCGTCTGCTGCCCGACATCTCCGCCGCCGGCTCGGCCCAGCGCGCCAATCAGGGCTACGCCACCGGCGACAAGG
CGGTGGGCGTGGCCGAGATCGACCTCAAGGCCACCTGGGAGCTGGACCTGTTCGGCCGCAATCAAGCCCGCATGGCCGAG
GCCAACGCCCTGCTGCAATCGGAGGAAGCCACCCGCCAGGGCGTGCGGGTGGCGCTGCTGGCCGAGGTGGCGCGGTCCTA
TTTCGACCTGCGCGACGCCATCCGCCAGATCGAATTGACCCGCCAGAACCTGGGAACCCAGCGCCGCACCCTGGAGATCA
TCCGCGCCCAGCGCCAGGGCGCCCTGGCCAGCGATTTCGACGTCCAGCGGGCCGGGGCCCGGGTCTCGGCCACCGAGGCC
CTGATTCCGTCCCTGGAGACCGCCCGCGACGTGGCCTTGAACCGGCTGTCCGTGCTGTTGGGCCGCGTGCCCGGCGGCCG
TGACGCCCTGCTGGCCGAACTGCCGCAGGCCAAGCCCCTCAATCCGAGCGTCGCCATCGCCGCCCCGGCCAAGGTGCTGG
CGGCACGGCCCGACGTGCGCGCCGCCGAGCGCCGCTTCGCCGCCAGCCTGTCGGCCAAGGACGCCGCCACCGCCGAACTG
TTTCCCAATATCTCGCTGGCCGCTCTGTTCGGCACCCAGACCGCCACCCCGATGAATGCCACGCCCTGGGGCATCGGCCT
GACCCTGGTCCAGCCGATCCTTAATTTCGGCCGCATCGAATCCCAGATCGACGCCGCCGACGCCCGCCAGCGCCAAGCCT
TCCTGGCCTATCAGCGCAGCGTGCTGGAAGCGCTGGAAGACATGGAAAACGCCCTGTCGCGCTATGGCCACGAAGCCGGC
CGCAATGTCGCGCTCGCCACCGGCGTGGCCCAAAATCGCCGGGCTTCGGAGCTGGCGCATACCCAGTTTACCAACGGCTA
TACCGGCCTGCTCGACGTCCTGGTGGCGGAACGCGACCTGCTGGACGCCGAAGCGGCCCAGGCCGCCTCCGATACCAGCC
TCCGCCGGAATCTGATCGCCATCTACGCCGCGGCGGGAGGCGGCTGGGACGACAGCGCCGACGGAAGGTGA

Upstream 100 bases:

>100_bases
CTGGGCGTCACGTTCTTCGGCCTGTTCCTCACCCCCGTCTTCTACGTCCTCATGCGCGCGCTGGAAAAGCGCGTCACCGG
AACCGAAAAGGTGCACCACC

Downstream 100 bases:

>100_bases
CCCGATGGCGCCATAAGCCCTGAAAAGGCAACGCCATTCCCCTGGTCAGACGGCGTCAGCCATGCTTCACTGATGCTCGT
TTTGGGGGCTGATGGGGGCC

Product: Outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSKRKIAPSALVLTGLLLAACTSPAGPQDSGIETPSLWSRLTGSAPAKADPTAPLVLGPDAEVEQTWWRRFGDPTLDTLV
ADALAGNQTLAMAKARVEEAQAARGLARSRLLPDISAAGSAQRANQGYATGDKAVGVAEIDLKATWELDLFGRNQARMAE
ANALLQSEEATRQGVRVALLAEVARSYFDLRDAIRQIELTRQNLGTQRRTLEIIRAQRQGALASDFDVQRAGARVSATEA
LIPSLETARDVALNRLSVLLGRVPGGRDALLAELPQAKPLNPSVAIAAPAKVLAARPDVRAAERRFAASLSAKDAATAEL
FPNISLAALFGTQTATPMNATPWGIGLTLVQPILNFGRIESQIDAADARQRQAFLAYQRSVLEALEDMENALSRYGHEAG
RNVALATGVAQNRRASELAHTQFTNGYTGLLDVLVAERDLLDAEAAQAASDTSLRRNLIAIYAAAGGGWDDSADGR

Sequences:

>Translated_476_residues
MSKRKIAPSALVLTGLLLAACTSPAGPQDSGIETPSLWSRLTGSAPAKADPTAPLVLGPDAEVEQTWWRRFGDPTLDTLV
ADALAGNQTLAMAKARVEEAQAARGLARSRLLPDISAAGSAQRANQGYATGDKAVGVAEIDLKATWELDLFGRNQARMAE
ANALLQSEEATRQGVRVALLAEVARSYFDLRDAIRQIELTRQNLGTQRRTLEIIRAQRQGALASDFDVQRAGARVSATEA
LIPSLETARDVALNRLSVLLGRVPGGRDALLAELPQAKPLNPSVAIAAPAKVLAARPDVRAAERRFAASLSAKDAATAEL
FPNISLAALFGTQTATPMNATPWGIGLTLVQPILNFGRIESQIDAADARQRQAFLAYQRSVLEALEDMENALSRYGHEAG
RNVALATGVAQNRRASELAHTQFTNGYTGLLDVLVAERDLLDAEAAQAASDTSLRRNLIAIYAAAGGGWDDSADGR
>Mature_475_residues
SKRKIAPSALVLTGLLLAACTSPAGPQDSGIETPSLWSRLTGSAPAKADPTAPLVLGPDAEVEQTWWRRFGDPTLDTLVA
DALAGNQTLAMAKARVEEAQAARGLARSRLLPDISAAGSAQRANQGYATGDKAVGVAEIDLKATWELDLFGRNQARMAEA
NALLQSEEATRQGVRVALLAEVARSYFDLRDAIRQIELTRQNLGTQRRTLEIIRAQRQGALASDFDVQRAGARVSATEAL
IPSLETARDVALNRLSVLLGRVPGGRDALLAELPQAKPLNPSVAIAAPAKVLAARPDVRAAERRFAASLSAKDAATAELF
PNISLAALFGTQTATPMNATPWGIGLTLVQPILNFGRIESQIDAADARQRQAFLAYQRSVLEALEDMENALSRYGHEAGR
NVALATGVAQNRRASELAHTQFTNGYTGLLDVLVAERDLLDAEAAQAASDTSLRRNLIAIYAAAGGGWDDSADGR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=462, Percent_Identity=28.3549783549784, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI2367348, Length=362, Percent_Identity=26.7955801104972, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50536; Mature: 50404

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRKIAPSALVLTGLLLAACTSPAGPQDSGIETPSLWSRLTGSAPAKADPTAPLVLGPD
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCC
AEVEQTWWRRFGDPTLDTLVADALAGNQTLAMAKARVEEAQAARGLARSRLLPDISAAGS
CCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
AQRANQGYATGDKAVGVAEIDLKATWELDLFGRNQARMAEANALLQSEEATRQGVRVALL
HHHCCCCCCCCCCCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
AEVARSYFDLRDAIRQIELTRQNLGTQRRTLEIIRAQRQGALASDFDVQRAGARVSATEA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHH
LIPSLETARDVALNRLSVLLGRVPGGRDALLAELPQAKPLNPSVAIAAPAKVLAARPDVR
HHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCHHHHHCCCCHH
AAERRFAASLSAKDAATAELFPNISLAALFGTQTATPMNATPWGIGLTLVQPILNFGRIE
HHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SQIDAADARQRQAFLAYQRSVLEALEDMENALSRYGHEAGRNVALATGVAQNRRASELAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCHHHHHHH
TQFTNGYTGLLDVLVAERDLLDAEAAQAASDTSLRRNLIAIYAAAGGGWDDSADGR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SKRKIAPSALVLTGLLLAACTSPAGPQDSGIETPSLWSRLTGSAPAKADPTAPLVLGPD
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCC
AEVEQTWWRRFGDPTLDTLVADALAGNQTLAMAKARVEEAQAARGLARSRLLPDISAAGS
CCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
AQRANQGYATGDKAVGVAEIDLKATWELDLFGRNQARMAEANALLQSEEATRQGVRVALL
HHHCCCCCCCCCCCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
AEVARSYFDLRDAIRQIELTRQNLGTQRRTLEIIRAQRQGALASDFDVQRAGARVSATEA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHH
LIPSLETARDVALNRLSVLLGRVPGGRDALLAELPQAKPLNPSVAIAAPAKVLAARPDVR
HHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCHHHHHCCCCHH
AAERRFAASLSAKDAATAELFPNISLAALFGTQTATPMNATPWGIGLTLVQPILNFGRIE
HHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SQIDAADARQRQAFLAYQRSVLEALEDMENALSRYGHEAGRNVALATGVAQNRRASELAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCHHHHHHH
TQFTNGYTGLLDVLVAERDLLDAEAAQAASDTSLRRNLIAIYAAAGGGWDDSADGR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]