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The map label for this gene is csd1 [H]

Identifier: 83310948

GI number: 83310948

Start: 1990714

End: 1992498

Strand: Reverse

Name: csd1 [H]

Synonym: amb1849

Alternate gene names: 83310948

Gene position: 1992498-1990714 (Counterclockwise)

Preceding gene: 83310949

Following gene: 83310942

Centisome position: 40.11

GC content: 69.86

Gene sequence:

>1785_bases
ATGACCCAGCCGCTCTCCCTCGAGCTGCCGTCTTCTCCCTCCCCGGCGGCATTGCCCGCCGGGGATTGGGAGGAACCGTC
AGCGGGCTTCGCCGGCGCCCCCGATGCCCGGCTGATCGCCCAGATGGCCAACGCCCTGTTCAGCGCCCAGCCCGGCCAGT
CGGCTCCCTCCTTCGGCGTGGCGCCGCCCTCGCTCCCGCTGATCGAGGCAGCCCCCACCGGCGGATTCGTGCCGCCCGGC
GTGCCGGCGCCCCCCTCGGTCGGCAACGTCACCCCGGTGCCTCAGGTGCCGCAGGTGGGACCGCTGGCCGCCGCCCCCGC
CGCCCCTCCCGGCAACCCTGCCGCCTTTCCGCCCACCGTGCTGCCGGGCGAGCCGGATTTGCGGGGCGTCCTCAACCAGT
TGGGCGACGTAGTGCGCCTAGTGCCTCCCGGCCACGGGATCGAGCCGCCCGCCGCCGCTCCAGAACCGCCGCCCGGTCCG
TCGACTGAGTCCCCCCCATTGCTGGCCATCGAGTTGCGGCCCGATCTGGTCCCCGACCTCAGGGGGACCTCGTCGCGGGT
CGGGGTCTTCGACGCCCATGCGGTCAAGCGCGACTTTCCCATCCTGAACCAGCAGGTTCACGGCAAGCCGCTGATCTGGC
TGGACAACGCCGCCACCACCCAGAAGCCGCGCCAGGTGATCGAACGCCTGACGCGCTATTACGAGCACGAGAACTCCAAC
ATCCACCGCGCCGCCCATGCCCTGGCGGCCCGCTCTACCGACGCCTACGAGGCGGCCCGGGAAAAGACCCGGCGCTTTCT
CAATGCCGGCTCCACCGAGGAAATCGTCTTCGTCAGGGGCGCCACCGAAGGCATCAACCTGATCGCCAAGGCCTGGGGCG
AGCGCAACGTGCGTGAAGGCGACGAGATCGTCGTCACCTGGCTGGAGCACCACGCCAACATCGTGCCCTGGCAGCAATTA
GCCGCCAAGGTTGGTGCCCGGCTGCGCGTCGCCCCGGTGGATGATTCGGGCCAGATCATCCTGGAGGAGTACGAGAAGCT
CCTGGGTCCCCGCACCCGCCTCGTCTCGCTGACCCAGGTGTCCAACGCGCTGGGCACCGTCACCCCGGCCGCTGAAATGA
CCGCCATGGCCCATCGCCACGGCGCACTGGTGCTGGTGGACGGCGCCCAGGCGGTGTCGCACATGCCCGTCGACGTCCAG
GCCCTGGACTGCGACTTCTACGTCTTTTCCGGCCACAAGGTGTTCGCCCCCACCGGCATCGGCGCGGTGTTCGGCAAAAA
GGCGGTGCTGGAGCACATGCCGCCCTGGCAGGGCGGCGGCAACATGATCGCCGACGTCACCTTCGAGAAGACCCTGTTCC
AGCCCGCCCCCGCCCGCTTCGAGGCGGGGACCGGCAACATCGCCGACGCGGTGGGTCTGGGGGCGGCCATCGACTACGTG
GAAGCCATCGGCATGGCGACCATCGCCGCCTGGGAGCATCAGTTGCTGGAATACGGCACCCAGGGGCTGCTCTCCATCCC
CGGCCTGCGCCTGGTCGGCACGGCGAAGGAGAAGGCCGGCGTGCTGTCCTTCGTCATCGATGGCTGCCGCACCGAGGACA
TCGGCAAGGCTCTCGACGGCGAGGGCATCGCCGTGCGCTCCGGCCATCACTGCGCCCAGCCCATCCTGCGCCGCTTCGGC
GTGGAATCCACGGTGCGGCCGTCACTGGCCTTCTACAACACGTACGAGGATCTGGACGCGTTGGTGAACGCGCTCAGACG
CCTCCCGTCGGCGCGGGGAATATAG

Upstream 100 bases:

>100_bases
TCTCGCTCTATTGCTCGGCCGCCTTGCTCACCGAGGATGCGCTGGCGGTGCTCGAGGATGTCGAGGTCGATCACTACTTC
GATTACGACAAGAAGTTCGC

Downstream 100 bases:

>100_bases
CGAAAGCGTCATGGCCGGGCTTGTCCCGGCCATCCACGCCGGATACTTCAGATGTCGTACATCAGCACCGTTTCGGCGCG
CGCCTTGCTGACCCGCATGT

Product: cysteine desulfurase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTQPLSLELPSSPSPAALPAGDWEEPSAGFAGAPDARLIAQMANALFSAQPGQSAPSFGVAPPSLPLIEAAPTGGFVPPG
VPAPPSVGNVTPVPQVPQVGPLAAAPAAPPGNPAAFPPTVLPGEPDLRGVLNQLGDVVRLVPPGHGIEPPAAAPEPPPGP
STESPPLLAIELRPDLVPDLRGTSSRVGVFDAHAVKRDFPILNQQVHGKPLIWLDNAATTQKPRQVIERLTRYYEHENSN
IHRAAHALAARSTDAYEAAREKTRRFLNAGSTEEIVFVRGATEGINLIAKAWGERNVREGDEIVVTWLEHHANIVPWQQL
AAKVGARLRVAPVDDSGQIILEEYEKLLGPRTRLVSLTQVSNALGTVTPAAEMTAMAHRHGALVLVDGAQAVSHMPVDVQ
ALDCDFYVFSGHKVFAPTGIGAVFGKKAVLEHMPPWQGGGNMIADVTFEKTLFQPAPARFEAGTGNIADAVGLGAAIDYV
EAIGMATIAAWEHQLLEYGTQGLLSIPGLRLVGTAKEKAGVLSFVIDGCRTEDIGKALDGEGIAVRSGHHCAQPILRRFG
VESTVRPSLAFYNTYEDLDALVNALRRLPSARGI

Sequences:

>Translated_594_residues
MTQPLSLELPSSPSPAALPAGDWEEPSAGFAGAPDARLIAQMANALFSAQPGQSAPSFGVAPPSLPLIEAAPTGGFVPPG
VPAPPSVGNVTPVPQVPQVGPLAAAPAAPPGNPAAFPPTVLPGEPDLRGVLNQLGDVVRLVPPGHGIEPPAAAPEPPPGP
STESPPLLAIELRPDLVPDLRGTSSRVGVFDAHAVKRDFPILNQQVHGKPLIWLDNAATTQKPRQVIERLTRYYEHENSN
IHRAAHALAARSTDAYEAAREKTRRFLNAGSTEEIVFVRGATEGINLIAKAWGERNVREGDEIVVTWLEHHANIVPWQQL
AAKVGARLRVAPVDDSGQIILEEYEKLLGPRTRLVSLTQVSNALGTVTPAAEMTAMAHRHGALVLVDGAQAVSHMPVDVQ
ALDCDFYVFSGHKVFAPTGIGAVFGKKAVLEHMPPWQGGGNMIADVTFEKTLFQPAPARFEAGTGNIADAVGLGAAIDYV
EAIGMATIAAWEHQLLEYGTQGLLSIPGLRLVGTAKEKAGVLSFVIDGCRTEDIGKALDGEGIAVRSGHHCAQPILRRFG
VESTVRPSLAFYNTYEDLDALVNALRRLPSARGI
>Mature_593_residues
TQPLSLELPSSPSPAALPAGDWEEPSAGFAGAPDARLIAQMANALFSAQPGQSAPSFGVAPPSLPLIEAAPTGGFVPPGV
PAPPSVGNVTPVPQVPQVGPLAAAPAAPPGNPAAFPPTVLPGEPDLRGVLNQLGDVVRLVPPGHGIEPPAAAPEPPPGPS
TESPPLLAIELRPDLVPDLRGTSSRVGVFDAHAVKRDFPILNQQVHGKPLIWLDNAATTQKPRQVIERLTRYYEHENSNI
HRAAHALAARSTDAYEAAREKTRRFLNAGSTEEIVFVRGATEGINLIAKAWGERNVREGDEIVVTWLEHHANIVPWQQLA
AKVGARLRVAPVDDSGQIILEEYEKLLGPRTRLVSLTQVSNALGTVTPAAEMTAMAHRHGALVLVDGAQAVSHMPVDVQA
LDCDFYVFSGHKVFAPTGIGAVFGKKAVLEHMPPWQGGGNMIADVTFEKTLFQPAPARFEAGTGNIADAVGLGAAIDYVE
AIGMATIAAWEHQLLEYGTQGLLSIPGLRLVGTAKEKAGVLSFVIDGCRTEDIGKALDGEGIAVRSGHHCAQPILRRFGV
ESTVRPSLAFYNTYEDLDALVNALRRLPSARGI

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=389, Percent_Identity=26.2210796915167, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI156713448, Length=437, Percent_Identity=25.4004576659039, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787970, Length=406, Percent_Identity=51.4778325123153, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1789175, Length=401, Percent_Identity=40.8977556109726, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI48994898, Length=391, Percent_Identity=27.6214833759591, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=216, Percent_Identity=26.3888888888889, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=350, Percent_Identity=26, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=30.1310043668122, Blast_Score=113, Evalue=7e-26,
Organism=Drosophila melanogaster, GI20129463, Length=401, Percent_Identity=27.431421446384, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 62701; Mature: 62570

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPLSLELPSSPSPAALPAGDWEEPSAGFAGAPDARLIAQMANALFSAQPGQSAPSFGV
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
APPSLPLIEAAPTGGFVPPGVPAPPSVGNVTPVPQVPQVGPLAAAPAAPPGNPAAFPPTV
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPGEPDLRGVLNQLGDVVRLVPPGHGIEPPAAAPEPPPGPSTESPPLLAIELRPDLVPDL
CCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
RGTSSRVGVFDAHAVKRDFPILNQQVHGKPLIWLDNAATTQKPRQVIERLTRYYEHENSN
CCCCCCCCEEEHHHHHHCCCHHCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
IHRAAHALAARSTDAYEAAREKTRRFLNAGSTEEIVFVRGATEGINLIAKAWGERNVREG
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCC
DEIVVTWLEHHANIVPWQQLAAKVGARLRVAPVDDSGQIILEEYEKLLGPRTRLVSLTQV
CCEEEEEHHHCCCCCCHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCHHHEEEHHHH
SNALGTVTPAAEMTAMAHRHGALVLVDGAQAVSHMPVDVQALDCDFYVFSGHKVFAPTGI
HHHHHCCCCHHHHHHHHHHCCCEEEEECHHHHHCCCCEEEEEEEEEEEEECCEEECCCCC
GAVFGKKAVLEHMPPWQGGGNMIADVTFEKTLFQPAPARFEAGTGNIADAVGLGAAIDYV
HHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
EAIGMATIAAWEHQLLEYGTQGLLSIPGLRLVGTAKEKAGVLSFVIDGCRTEDIGKALDG
HHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHCCC
EGIAVRSGHHCAQPILRRFGVESTVRPSLAFYNTYEDLDALVNALRRLPSARGI
CCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQPLSLELPSSPSPAALPAGDWEEPSAGFAGAPDARLIAQMANALFSAQPGQSAPSFGV
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
APPSLPLIEAAPTGGFVPPGVPAPPSVGNVTPVPQVPQVGPLAAAPAAPPGNPAAFPPTV
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPGEPDLRGVLNQLGDVVRLVPPGHGIEPPAAAPEPPPGPSTESPPLLAIELRPDLVPDL
CCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
RGTSSRVGVFDAHAVKRDFPILNQQVHGKPLIWLDNAATTQKPRQVIERLTRYYEHENSN
CCCCCCCCEEEHHHHHHCCCHHCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
IHRAAHALAARSTDAYEAAREKTRRFLNAGSTEEIVFVRGATEGINLIAKAWGERNVREG
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCC
DEIVVTWLEHHANIVPWQQLAAKVGARLRVAPVDDSGQIILEEYEKLLGPRTRLVSLTQV
CCEEEEEHHHCCCCCCHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCHHHEEEHHHH
SNALGTVTPAAEMTAMAHRHGALVLVDGAQAVSHMPVDVQALDCDFYVFSGHKVFAPTGI
HHHHHCCCCHHHHHHHHHHCCCEEEEECHHHHHCCCCEEEEEEEEEEEEECCEEECCCCC
GAVFGKKAVLEHMPPWQGGGNMIADVTFEKTLFQPAPARFEAGTGNIADAVGLGAAIDYV
HHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
EAIGMATIAAWEHQLLEYGTQGLLSIPGLRLVGTAKEKAGVLSFVIDGCRTEDIGKALDG
HHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHCCC
EGIAVRSGHHCAQPILRRFGVESTVRPSLAFYNTYEDLDALVNALRRLPSARGI
CCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]