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The map label for this gene is ppiD [H]

Identifier: 83310913

GI number: 83310913

Start: 1954403

End: 1956274

Strand: Reverse

Name: ppiD [H]

Synonym: amb1814

Alternate gene names: 83310913

Gene position: 1956274-1954403 (Counterclockwise)

Preceding gene: 83310923

Following gene: 83310912

Centisome position: 39.38

GC content: 67.68

Gene sequence:

>1872_bases
ATGCTCGACGTATTTCGCACCGCTTCGAAGACCTGGATCGTCAGGTTACTGTTCGCCCTTCTGGCCCTGAGCTTCGTGGC
CTGGGGCGCCGGCGACGTGGTCCGCGGCGGCGTCGGCCGCAGCCCGGCCATCGAGATCGGCCGCACCTCCATGTCGGCGG
CCGAGGTCATGGGTGAGTTCAAGCGCGAGGTCGAGCGTCTGCAGCCGTTGTTCGGCGGCAAGCTGACCGCCGAGGACGCC
CGCAAGATGGGCATGCTGGACCGCACCATCGATTCGCTGATCGCCCGCACCCTGATCGACGAGGCGGCCCGCTCGCTGGG
CCTTGCCGCCACCGACGAGACCATTTTGCGCCGTGTGGCCTCCAACCCCGCCTTCAAGGGGCCGACGGGCCAGTTCGACC
GCGACCTCTTCCGCTCGCGCCTCTCGCGCCTTGGCCACACCGAGGACAGCTTCATGAAGACCGAGCGCACCAACATGGTG
CGCAACCAGATGGTGGAGACCGTCGCCGCCGGCATCGGCGCGCCCCAGGCCCTGACCGATCCGCTGCTGGCCTGGCGGGA
GGAGCGCCGGGTGGCCGAGACCTTCCTGATCAAGGATGAGTCCACGCCCCTGCCCGCCGCCCCCGACGCGGCCGTGCTGG
AAGCCTATTACAAGGACAACGTCAGCCGGTTCATGGCGCCGGAATTCCGGGCGCTGACCGTTCTGCTGCTGCGTCCCTCC
GACGTGGCCGGCGGCATCGACATCGACGAGGAGATGGTGCGCGACGCTTACCGGCAGCGCATCGAGGAATTCTCCACGCC
GGAACGCCGCGCCGTGTCGCAGATCGTCTTCGACGAGTCTTCCGCCGCCGCCAAGGCCACCGATCTGGTGACCGGGGGCA
AGGATCTGGCGACCATTGCTAAGGCTCTGAACAGCGAGATCATCGATCTGGGCGTCATCGAGAAGAACGACCTGCCCGAA
GGACTGGCCGAGGCGGTGTTCAAGCTGTCCTCCGGCGCCACCAGCCAACCCGTCAAGACGGCGCTGGGCTGGCACGTGGT
CAAGGTCTCTCAGATTCAGCCCGGCCGCACCCGCTCCTTCGACGAGGTCAAGGCGCAACTGGAGCAGGACATGCGCAAGG
AAAAGGCCACGGACGGCCTGTCCGAACTGGCCAATCGCGTTGAGGACGCGTTGGGCGGCGGCGCCACCCTGGAAGAAGCG
GCCAAGCGCCACAACCTCAAGACCGTCAAGATCGCCGCCGTGGACGCTCAGGGCCGCGGTGCCGACGGCAAGCCGGTGGC
CGATCTTCCCAAATCCGACCAGTTCCTGGACGTGGCCTTCCACACCGACCAAAACACCGAAAGCCCGCTGACCGAAGTGC
CCAATAACGGCTACTTCCTGCTGCACGTCGATGGCGTCACCGCGCCCGCTCCCAAGCCCTTGGCCGAGATCAGGTCCGAG
GTGGTCGCCACCTGGCAGGCCGAACGCCGCCAGGAGCAGGCCCGCGACAAGGCCCTGAAGCTGGCTGACCGCATCAAGGT
CGGCGAAGGCATCGCCCAGGTGGCCCTTTCGGCCGGCGCCAAGCTGGAAACCTCGAAGCCGTTCGTCCGCGAGCCGGCCG
AAGGCACAGCGCTGCCGGCCACCATCATCGCCGAACTGTTCAAGGCCCAGCCGGGAGGAATCGCCACCGCGCCGGTCCAG
GGCGGCACCCTGGTGGCCCGACTGGCCAAGGTGGTGACCTTCGACACCAACGCCAATCCCGCCCTGACCCAGGCGGCCCG
CCAGCGCGTGTCGCAGGCGGTGGCCACCGACATTGCCGACCAGTACATCGCCGCCCTGAACGCCTCCATCGGCGTCAAGG
TGGACCGTCCCCAACTGACCCGCGAAGAGTAG

Upstream 100 bases:

>100_bases
TCCATGTTGCGGCCCCCCTGCCCCCTCCTTATTATGCCGCCAGCCCAGGGCGGCCGGCATCCGGCACGCCCCAACATCTT
TTGCGGACTCGGCCCAATCC

Downstream 100 bases:

>100_bases
CAGCGTCACCATGAGCCATCAGCCCGACTTCTCCGCCTTTGCCGCAGCCTATGACGATGGCAAGCCTCAGGTGGTCTGGC
GGGTGTTGGTGGCCGACCTG

Product: parvulin-like peptidyl-prolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MLDVFRTASKTWIVRLLFALLALSFVAWGAGDVVRGGVGRSPAIEIGRTSMSAAEVMGEFKREVERLQPLFGGKLTAEDA
RKMGMLDRTIDSLIARTLIDEAARSLGLAATDETILRRVASNPAFKGPTGQFDRDLFRSRLSRLGHTEDSFMKTERTNMV
RNQMVETVAAGIGAPQALTDPLLAWREERRVAETFLIKDESTPLPAAPDAAVLEAYYKDNVSRFMAPEFRALTVLLLRPS
DVAGGIDIDEEMVRDAYRQRIEEFSTPERRAVSQIVFDESSAAAKATDLVTGGKDLATIAKALNSEIIDLGVIEKNDLPE
GLAEAVFKLSSGATSQPVKTALGWHVVKVSQIQPGRTRSFDEVKAQLEQDMRKEKATDGLSELANRVEDALGGGATLEEA
AKRHNLKTVKIAAVDAQGRGADGKPVADLPKSDQFLDVAFHTDQNTESPLTEVPNNGYFLLHVDGVTAPAPKPLAEIRSE
VVATWQAERRQEQARDKALKLADRIKVGEGIAQVALSAGAKLETSKPFVREPAEGTALPATIIAELFKAQPGGIATAPVQ
GGTLVARLAKVVTFDTNANPALTQAARQRVSQAVATDIADQYIAALNASIGVKVDRPQLTREE

Sequences:

>Translated_623_residues
MLDVFRTASKTWIVRLLFALLALSFVAWGAGDVVRGGVGRSPAIEIGRTSMSAAEVMGEFKREVERLQPLFGGKLTAEDA
RKMGMLDRTIDSLIARTLIDEAARSLGLAATDETILRRVASNPAFKGPTGQFDRDLFRSRLSRLGHTEDSFMKTERTNMV
RNQMVETVAAGIGAPQALTDPLLAWREERRVAETFLIKDESTPLPAAPDAAVLEAYYKDNVSRFMAPEFRALTVLLLRPS
DVAGGIDIDEEMVRDAYRQRIEEFSTPERRAVSQIVFDESSAAAKATDLVTGGKDLATIAKALNSEIIDLGVIEKNDLPE
GLAEAVFKLSSGATSQPVKTALGWHVVKVSQIQPGRTRSFDEVKAQLEQDMRKEKATDGLSELANRVEDALGGGATLEEA
AKRHNLKTVKIAAVDAQGRGADGKPVADLPKSDQFLDVAFHTDQNTESPLTEVPNNGYFLLHVDGVTAPAPKPLAEIRSE
VVATWQAERRQEQARDKALKLADRIKVGEGIAQVALSAGAKLETSKPFVREPAEGTALPATIIAELFKAQPGGIATAPVQ
GGTLVARLAKVVTFDTNANPALTQAARQRVSQAVATDIADQYIAALNASIGVKVDRPQLTREE
>Mature_623_residues
MLDVFRTASKTWIVRLLFALLALSFVAWGAGDVVRGGVGRSPAIEIGRTSMSAAEVMGEFKREVERLQPLFGGKLTAEDA
RKMGMLDRTIDSLIARTLIDEAARSLGLAATDETILRRVASNPAFKGPTGQFDRDLFRSRLSRLGHTEDSFMKTERTNMV
RNQMVETVAAGIGAPQALTDPLLAWREERRVAETFLIKDESTPLPAAPDAAVLEAYYKDNVSRFMAPEFRALTVLLLRPS
DVAGGIDIDEEMVRDAYRQRIEEFSTPERRAVSQIVFDESSAAAKATDLVTGGKDLATIAKALNSEIIDLGVIEKNDLPE
GLAEAVFKLSSGATSQPVKTALGWHVVKVSQIQPGRTRSFDEVKAQLEQDMRKEKATDGLSELANRVEDALGGGATLEEA
AKRHNLKTVKIAAVDAQGRGADGKPVADLPKSDQFLDVAFHTDQNTESPLTEVPNNGYFLLHVDGVTAPAPKPLAEIRSE
VVATWQAERRQEQARDKALKLADRIKVGEGIAQVALSAGAKLETSKPFVREPAEGTALPATIIAELFKAQPGGIATAPVQ
GGTLVARLAKVVTFDTNANPALTQAARQRVSQAVATDIADQYIAALNASIGVKVDRPQLTREE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=610, Percent_Identity=25.9016393442623, Blast_Score=166, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67307; Mature: 67307

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVFRTASKTWIVRLLFALLALSFVAWGAGDVVRGGVGRSPAIEIGRTSMSAAEVMGEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHCCCHHHHHHHHHHH
KREVERLQPLFGGKLTAEDARKMGMLDRTIDSLIARTLIDEAARSLGLAATDETILRRVA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SNPAFKGPTGQFDRDLFRSRLSRLGHTEDSFMKTERTNMVRNQMVETVAAGIGAPQALTD
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
PLLAWREERRVAETFLIKDESTPLPAAPDAAVLEAYYKDNVSRFMAPEFRALTVLLLRPS
HHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEEEECCC
DVAGGIDIDEEMVRDAYRQRIEEFSTPERRAVSQIVFDESSAAAKATDLVTGGKDLATIA
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHH
KALNSEIIDLGVIEKNDLPEGLAEAVFKLSSGATSQPVKTALGWHVVKVSQIQPGRTRSF
HHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCEEEEEEECCCCCCCCCH
DEVKAQLEQDMRKEKATDGLSELANRVEDALGGGATLEEAAKRHNLKTVKIAAVDAQGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCC
ADGKPVADLPKSDQFLDVAFHTDQNTESPLTEVPNNGYFLLHVDGVTAPAPKPLAEIRSE
CCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCHHHHHHH
VVATWQAERRQEQARDKALKLADRIKVGEGIAQVALSAGAKLETSKPFVREPAEGTALPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCHH
TIIAELFKAQPGGIATAPVQGGTLVARLAKVVTFDTNANPALTQAARQRVSQAVATDIAD
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
QYIAALNASIGVKVDRPQLTREE
HHHHHHCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MLDVFRTASKTWIVRLLFALLALSFVAWGAGDVVRGGVGRSPAIEIGRTSMSAAEVMGEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHCCCHHHHHHHHHHH
KREVERLQPLFGGKLTAEDARKMGMLDRTIDSLIARTLIDEAARSLGLAATDETILRRVA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SNPAFKGPTGQFDRDLFRSRLSRLGHTEDSFMKTERTNMVRNQMVETVAAGIGAPQALTD
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
PLLAWREERRVAETFLIKDESTPLPAAPDAAVLEAYYKDNVSRFMAPEFRALTVLLLRPS
HHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEEEECCC
DVAGGIDIDEEMVRDAYRQRIEEFSTPERRAVSQIVFDESSAAAKATDLVTGGKDLATIA
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHH
KALNSEIIDLGVIEKNDLPEGLAEAVFKLSSGATSQPVKTALGWHVVKVSQIQPGRTRSF
HHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCEEEEEEECCCCCCCCCH
DEVKAQLEQDMRKEKATDGLSELANRVEDALGGGATLEEAAKRHNLKTVKIAAVDAQGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCC
ADGKPVADLPKSDQFLDVAFHTDQNTESPLTEVPNNGYFLLHVDGVTAPAPKPLAEIRSE
CCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCHHHHHHH
VVATWQAERRQEQARDKALKLADRIKVGEGIAQVALSAGAKLETSKPFVREPAEGTALPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCHH
TIIAELFKAQPGGIATAPVQGGTLVARLAKVVTFDTNANPALTQAARQRVSQAVATDIAD
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
QYIAALNASIGVKVDRPQLTREE
HHHHHHCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]