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The map label for this gene is uppP2

Identifier: 83310646

GI number: 83310646

Start: 1678064

End: 1678849

Strand: Reverse

Name: uppP2

Synonym: amb1547

Alternate gene names: 83310646

Gene position: 1678849-1678064 (Counterclockwise)

Preceding gene: 83310647

Following gene: 83310643

Centisome position: 33.8

GC content: 65.78

Gene sequence:

>786_bases
ATGCTTGAAGCCCTGCTCCTCGGTGTCGTCGAGGGCCTGACCGAATTCCTGCCCATCTCCAGCACCGCCCATCTGATGCT
GATCGGCGACATGCTCGGATTCGAGGGACCACCCGGCAAGACCTACGAGATCGTCGTCCAGTTGGGCGCCATCCTGGCAG
TCTGCGTGGTGTTCCGCCAGCGCCTGTGGGGCGTGGCGACCACCATCACCCAGCCGCGCTCCTTCGCCTTCGCCCGCAAC
GTCATGGTGGCGTTCCTGCCGGCGGCGGTGATCGGGGCCACGTTGTACAAGTACATCAAGCAGATGCTGGAATCGCCGCT
GGTCGCCGCCATCGCCCTGGTGGTGGGCGGCGTCGCCATCCTGGTCATCGAGCGTCTGGTGAAAAGAGCCCGTATCCACG
ATATCGAGGACATGTCCCCCGCTTTGGCCCTGGGTGTCGGATTCTGCCAGGTCCTGGCCATGGTGCCCGGCGTGTCCCGG
GCCGGCGCCACCATCATGGGCTCCATGCTGCTGGGCCTCGACCGCCGGGCCGCCGCCGAGTTTTCGTTCTTCCTGGCCAT
CCCCACCATGTGCGGCGCTTCGGCCTATTCCCTGTATAAGAACTGGGCCACCCTGTCCTTCGACGGCGCCGGCCTGATCG
CTCTGGGCTTCGTCGCGGCCTTCCTGTCCGCCCTGGTGGTGGTCAAGGGCTTCATCGGCTTTGTCGGCCGCCACGGCTTC
GCCCCCTTCGCCTGGTACCGGATCGCCTTCGGCTCGTTGATGGCGGTTCTGATCCTGATGCGCTGA

Upstream 100 bases:

>100_bases
CAAGTGTCTCTGCCGTCCCCCGTTTACCGGTTGCGAAAACCGGCCTCCCCGCCCATGATCCGGCCCGACCGCAACCCCGA
TTGGATCCTCCATGCTTGCC

Downstream 100 bases:

>100_bases
GGAAGCGGCCGTCCGACCCCGGCGTCGGACGGCCCGCCGTCACCCTCTTGGGCTATCGCCCAAAACCCATCCGGGGAGAA
CCCCGGTCCCCCCTTATCTT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLEALLLGVVEGLTEFLPISSTAHLMLIGDMLGFEGPPGKTYEIVVQLGAILAVCVVFRQRLWGVATTITQPRSFAFARN
VMVAFLPAAVIGATLYKYIKQMLESPLVAAIALVVGGVAILVIERLVKRARIHDIEDMSPALALGVGFCQVLAMVPGVSR
AGATIMGSMLLGLDRRAAAEFSFFLAIPTMCGASAYSLYKNWATLSFDGAGLIALGFVAAFLSALVVVKGFIGFVGRHGF
APFAWYRIAFGSLMAVLILMR

Sequences:

>Translated_261_residues
MLEALLLGVVEGLTEFLPISSTAHLMLIGDMLGFEGPPGKTYEIVVQLGAILAVCVVFRQRLWGVATTITQPRSFAFARN
VMVAFLPAAVIGATLYKYIKQMLESPLVAAIALVVGGVAILVIERLVKRARIHDIEDMSPALALGVGFCQVLAMVPGVSR
AGATIMGSMLLGLDRRAAAEFSFFLAIPTMCGASAYSLYKNWATLSFDGAGLIALGFVAAFLSALVVVKGFIGFVGRHGF
APFAWYRIAFGSLMAVLILMR
>Mature_261_residues
MLEALLLGVVEGLTEFLPISSTAHLMLIGDMLGFEGPPGKTYEIVVQLGAILAVCVVFRQRLWGVATTITQPRSFAFARN
VMVAFLPAAVIGATLYKYIKQMLESPLVAAIALVVGGVAILVIERLVKRARIHDIEDMSPALALGVGFCQVLAMVPGVSR
AGATIMGSMLLGLDRRAAAEFSFFLAIPTMCGASAYSLYKNWATLSFDGAGLIALGFVAAFLSALVVVKGFIGFVGRHGF
APFAWYRIAFGSLMAVLILMR

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=256, Percent_Identity=43.75, Blast_Score=196, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_MAGSA (Q2W724)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_420910.1
- STRING:   Q2W724
- GeneID:   3806467
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb1547
- NMPDR:   fig|342108.5.peg.1380
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   PERENVT
- PhylomeDB:   Q2W724
- ProtClustDB:   PRK00281
- BioCyc:   MMAG342108:AMB1547-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 27808; Mature: 27808

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x103e6de8)-; HASH(0x1116030c)-; HASH(0x11b8400c)-; HASH(0x11b83e20)-; HASH(0x1168bdc8)-; HASH(0x116fdc84)-; HASH(0x116fdc9c)-; HASH(0x114ba69c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEALLLGVVEGLTEFLPISSTAHLMLIGDMLGFEGPPGKTYEIVVQLGAILAVCVVFRQ
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RLWGVATTITQPRSFAFARNVMVAFLPAAVIGATLYKYIKQMLESPLVAAIALVVGGVAI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LVIERLVKRARIHDIEDMSPALALGVGFCQVLAMVPGVSRAGATIMGSMLLGLDRRAAAE
HHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHH
FSFFLAIPTMCGASAYSLYKNWATLSFDGAGLIALGFVAAFLSALVVVKGFIGFVGRHGF
HHHHHHHHHHHCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APFAWYRIAFGSLMAVLILMR
CHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLEALLLGVVEGLTEFLPISSTAHLMLIGDMLGFEGPPGKTYEIVVQLGAILAVCVVFRQ
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RLWGVATTITQPRSFAFARNVMVAFLPAAVIGATLYKYIKQMLESPLVAAIALVVGGVAI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LVIERLVKRARIHDIEDMSPALALGVGFCQVLAMVPGVSRAGATIMGSMLLGLDRRAAAE
HHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHH
FSFFLAIPTMCGASAYSLYKNWATLSFDGAGLIALGFVAAFLSALVVVKGFIGFVGRHGF
HHHHHHHHHHHCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APFAWYRIAFGSLMAVLILMR
CHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA